CD137 Monoclonal Antibody (4B4-1), Alexa Fluor 647 | Invitrogen A51019 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD137 Monoclonal Antibody (4B4-1), Alexa Fluor 647

catalog :

A51019

quantity :

100 Tests

price :

US 385.00

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

4B4-1

The same clone is also sold as:

Abcam: ab234169
BioLegend: 309847, 309845, 309802, 309803, 309831, 309852, 309818, 309841, 309809, 309830, 309822, 309821, 309833, 309850, 309810, 309806, 309848, 309844, 309819, 309825, 309843, 309824, 309827, 309813, 309853, 309849, 309804, 309814, 309820, 309837, 309823, 309851, 309826, 309828, 309839, 309808, 309817, 309829, 309842, 309816, 309832, 309835, 309834
Bio-Rad: MCA6117APC, MCA6117
Exbio: 1P-143-T100, 12-143-C100, 1P-143-T025, 11-143-C100, 1A-143-T100, 11-143-C025
BD Biosciences: 555956, 555955, 552533, 561702, 550890

reactivity :

human

application :

flow cytometry

citations: 3

Reference
Foldvari Z, Knetter C, Yang W, Gjerdingen T, Bollineni R, Tran T, et al. A systematic safety pipeline for selection of T-cell receptors to enter clinical use. NPJ Vaccines. 2023;8:126 pubmed publisher
Meyer S, Blaas I, Bollineni R, Delic Sarac M, Tran T, Knetter C, et al. Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants. Cell Rep. 2023;42:111995 pubmed publisher
Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, et al. Anti-tumour immunity induces aberrant peptide presentation in melanoma. Nature. 2021;590:332-337 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD137 Monoclonal Antibody (4B4-1), Alexa Fluor 647

Catalog # :

A51019

Quantity :

100 Tests

Price :

US 385.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 5 uL/1x10^6 cells

Species :

Human

Clone :

4B4-1

Isotype :

IgG1

Storage :

4 C, store in dark

Description :

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.

Immunogen :

Recombinant human CD137 ectodomain

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 uL/1x10^6 cells

Aliases :

4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9