| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; 1:500; loading ...; fig 1b
| Wanet A, Caruso M, Domelevo Entfellner J, Najar M, Fattaccioli A, Demazy C, et al. The Transcription Factor 7-Like 2-Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Axis Connects Mitochondrial Biogenesis and Metabolic Shift with Stem Cell Commitment to Hepatic Differentiation. Stem Cells. 2017;35:2184-2197 pubmed publisher |
- western blot; mouse; loading ...; fig 6b
| Schatton D, Pla Martín D, Marx M, Hansen H, Mourier A, Nemazanyy I, et al. CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017;216:675-693 pubmed publisher |
- western blot; mouse; loading ...; fig 5c
| Volonte D, Liu Z, Shiva S, Galbiati F. Caveolin-1 controls mitochondrial function through regulation of m-AAA mitochondrial protease. Aging (Albany NY). 2016;8:2355-2369 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5e
| Spendiff S, Vuda M, Gouspillou G, Aare S, Pérez A, Morais J, et al. Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol. 2016;594:7361-7379 pubmed publisher |
- western blot; mouse; loading ...; fig 3d
| Yan S, Du F, Wu L, Zhang Z, Zhong C, Yu Q, et al. F1F0 ATP Synthase-Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline. Diabetes. 2016;65:3482-3494 pubmed |
- western blot; mouse; loading ...; fig 5c
| Liu J, Liu J, Holmström K, Menazza S, Parks R, Fergusson M, et al. MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload. Cell Rep. 2016;16:1561-1573 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed publisher |
- western blot; mouse; fig 1
| Hwang H, Dornbos P, Steidemann M, Dunivin T, Rizzo M, LaPres J. Mitochondrial-targeted aryl hydrocarbon receptor and the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cellular respiration and the mitochondrial proteome. Toxicol Appl Pharmacol. 2016;304:121-32 pubmed publisher |
- western blot; mouse; fig 1
| Aizawa S, Fujiwara Y, Contu V, Hase K, Takahashi M, Kikuchi H, et al. Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes. Autophagy. 2016;12:565-78 pubmed publisher |
- western blot; mouse; 1:2000; fig 1
| Nomura M, Liu J, Rovira I, Gonzalez Hurtado E, Lee J, Wolfgang M, et al. Fatty acid oxidation in macrophage polarization. Nat Immunol. 2016;17:216-7 pubmed publisher |
- western blot; human; 1:2000; fig 7
| E L, Swerdlow R. Lactate's effect on human neuroblastoma cell bioenergetic fluxes. Biochem Pharmacol. 2016;99:88-100 pubmed publisher |
| Mattiolo P, Yuste V, Boix J, Ribas J. Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation. Biochem Pharmacol. 2015;98:573-86 pubmed publisher |
| Ferry A, Parlakian A, Joanne P, Fraysse B, Mgrditchian T, Roy P, et al. Mechanical Overloading Increases Maximal Force and Reduces Fragility in Hind Limb Skeletal Muscle from Mdx Mouse. Am J Pathol. 2015;185:2012-24 pubmed publisher |
| Michel S, Canonne M, Arnould T, Renard P. Inhibition of mitochondrial genome expression triggers the activation of CHOP-10 by a cell signaling dependent on the integrated stress response but not the mitochondrial unfolded protein response. Mitochondrion. 2015;21:58-68 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Zhou L, Park S, Xu L, Xia X, Ye J, Su L, et al. Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice. Nat Commun. 2015;6:5949 pubmed publisher |
- western blot; rat; 1:200000
| Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed publisher |
- immunohistochemistry; mouse; 1:750
| de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed |
| White A, Philp A, Fridolfsson H, Schilling J, Murphy A, Hamilton D, et al. High-fat diet-induced impairment of skeletal muscle insulin sensitivity is not prevented by SIRT1 overexpression. Am J Physiol Endocrinol Metab. 2014;307:E764-72 pubmed publisher |
- western blot; mouse; 1:1000
| Jousse C, Muranishi Y, Parry L, Montaurier C, Even P, Launay J, et al. Perinatal protein malnutrition affects mitochondrial function in adult and results in a resistance to high fat diet-induced obesity. PLoS ONE. 2014;9:e104896 pubmed publisher |
- western blot; human; 1:500; fig s1
| Wanet A, Remacle N, Najar M, Sokal E, Arnould T, Najimi M, et al. Mitochondrial remodeling in hepatic differentiation and dedifferentiation. Int J Biochem Cell Biol. 2014;54:174-85 pubmed publisher |
- western blot; mouse; 1:2000
| E L, Burns J, Swerdlow R. Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. Neurobiol Aging. 2014;35:2574-2583 pubmed publisher |
| Watanabe M, Funakoshi T, Unuma K, Aki T, Uemura K. Activation of the ubiquitin-proteasome system against arsenic trioxide cardiotoxicity involves ubiquitin ligase Parkin for mitochondrial homeostasis. Toxicology. 2014;322:43-50 pubmed publisher |
- western blot; human; 1:1000
| Tan E, Villar M, E L, Lu J, Selfridge J, Artigues A, et al. Altering O-linked ?-N-acetylglucosamine cycling disrupts mitochondrial function. J Biol Chem. 2014;289:14719-30 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100
- immunocytochemistry; mouse; fig 1
- western blot; mouse
| Laker R, Xu P, Ryall K, Sujkowski A, Kenwood B, Chain K, et al. A novel MitoTimer reporter gene for mitochondrial content, structure, stress, and damage in vivo. J Biol Chem. 2014;289:12005-15 pubmed publisher |
- western blot; mouse; fig 7
| Tappenden D, Hwang H, Yang L, Thomas R, LaPres J. The Aryl-Hydrocarbon Receptor Protein Interaction Network (AHR-PIN) as Identified by Tandem Affinity Purification (TAP) and Mass Spectrometry. J Toxicol. 2013;2013:279829 pubmed publisher |
| Wang C, Wang J, Liu Z, Ma X, Wang X, Jin H, et al. Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma. Carcinogenesis. 2014;35:1500-9 pubmed publisher |
- western blot; mouse; 1:2,000
| Yoshioka H, Katsu M, Sakata H, Okami N, Wakai T, Kinouchi H, et al. The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J Cereb Blood Flow Metab. 2013;33:1658-65 pubmed publisher |
- western blot; mouse; 1:10000; fig 4
| Wallace M, Russell A. Striated muscle activator of Rho signaling is required for myotube survival but does not influence basal protein synthesis or degradation. Am J Physiol Cell Physiol. 2013;305:C414-26 pubmed publisher |
- western blot; mouse; fig 2
| Kim S, Asaka M, Higashida K, Takahashi Y, Holloszy J, Han D. ?-Adrenergic stimulation does not activate p38 MAP kinase or induce PGC-1? in skeletal muscle. Am J Physiol Endocrinol Metab. 2013;304:E844-52 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Menzies K, Singh K, Saleem A, Hood D. Sirtuin 1-mediated effects of exercise and resveratrol on mitochondrial biogenesis. J Biol Chem. 2013;288:6968-79 pubmed publisher |
- western blot; mouse; fig 5
| Akundi R, Zhi L, Sullivan P, Bueler H. Shared and cell type-specific mitochondrial defects and metabolic adaptations in primary cells from PINK1-deficient mice. Neurodegener Dis. 2013;12:136-49 pubmed publisher |
- western blot; mouse; fig 2
| Li B, Chauvin C, De Paulis D, De Oliveira F, Gharib A, Vial G, et al. Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D. Biochim Biophys Acta. 2012;1817:1628-34 pubmed publisher |
| Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, et al. Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes. PLoS ONE. 2012;7:e37378 pubmed publisher |
- western blot; mouse; 1:2000; fig 11
| E L, Lu J, Burns J, Swerdlow R. Effect of exercise on mouse liver and brain bioenergetic infrastructures. Exp Physiol. 2013;98:207-19 pubmed publisher |
- western blot; mouse; 1:800; fig 4
| Rouviere C, Corona B, Ingalls C. Oxidative capacity and fatigability in run-trained malignant hyperthermia-susceptible mice. Muscle Nerve. 2012;45:586-96 pubmed publisher |
- western blot; mouse; fig 3
| Sun Y, Yang D, Kuan C. Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis. J Neurosci Methods. 2012;203:122-9 pubmed publisher |
- immunohistochemistry; rat; 1:1000; fig 8
| Esteve Rudd J, Fernández Sánchez L, Lax P, de Juan E, Martín Nieto J, Cuenca N. Rotenone induces degeneration of photoreceptors and impairs the dopaminergic system in the rat retina. Neurobiol Dis. 2011;44:102-15 pubmed publisher |
- western blot; mouse; 1:500; fig 1
| Uguccioni G, Hood D. The importance of PGC-1? in contractile activity-induced mitochondrial adaptations. Am J Physiol Endocrinol Metab. 2011;300:E361-71 pubmed publisher |
- western blot; human; 0.5 ug/ml; fig 4
| Lu J, Wang K, Rodova M, Esteves R, Berry D, E L, et al. Polymorphic variation in cytochrome oxidase subunit genes. J Alzheimers Dis. 2010;21:141-54 pubmed publisher |
- immunohistochemistry - paraffin section; rat
- western blot; rat; 1:1000
| Ogawa K, Harada K, Endo Y, Sagawa S, Inoue M. Heterogeneous levels of oxidative phosphorylation enzymes in rat adrenal glands. Acta Histochem. 2011;113:24-31 pubmed publisher |
| Roudier E, Chapados N, Decary S, Gineste C, Le Bel C, Lavoie J, et al. Angiomotin p80/p130 ratio: a new indicator of exercise-induced angiogenic activity in skeletal muscles from obese and non-obese rats?. J Physiol. 2009;587:4105-19 pubmed publisher |
- western blot; rat; 1:100; fig 1d
| Weisová P, Concannon C, Devocelle M, Prehn J, Ward M. Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. J Neurosci. 2009;29:2997-3008 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Mitsuishi M, Miyashita K, Itoh H. cGMP rescues mitochondrial dysfunction induced by glucose and insulin in myocytes. Biochem Biophys Res Commun. 2008;367:840-5 pubmed publisher |
- western blot; mouse; fig 1
| Jin J, Whittaker R, Glassy M, Barlow S, Gottlieb R, Glembotski C. Localization of phosphorylated alphaB-crystallin to heart mitochondria during ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2008;294:H337-44 pubmed |
| Oishi Y, Ogata T, Yamamoto K, Terada M, Ohira T, Ohira Y, et al. Cellular adaptations in soleus muscle during recovery after hindlimb unloading. Acta Physiol (Oxf). 2008;192:381-95 pubmed |
- western blot; human; 1:1000; fig 1
| Campian J, Gao X, Qian M, Eaton J. Cytochrome C oxidase activity and oxygen tolerance. J Biol Chem. 2007;282:12430-8 pubmed |
- western blot; mouse; fig 6
| Adhami F, Liao G, Morozov Y, Schloemer A, Schmithorst V, Lorenz J, et al. Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy. Am J Pathol. 2006;169:566-83 pubmed |
- western blot; rat; 1:5000
| Endo H, Kamada H, Nito C, Nishi T, Chan P. Mitochondrial translocation of p53 mediates release of cytochrome c and hippocampal CA1 neuronal death after transient global cerebral ischemia in rats. J Neurosci. 2006;26:7974-83 pubmed |
| Ming L, Wang P, Bank A, Yu J, Zhang L. PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells. J Biol Chem. 2006;281:16034-42 pubmed |
- western blot; African green monkey
| Sarkar S, Floto R, Berger Z, Imarisio S, Cordenier A, Pasco M, et al. Lithium induces autophagy by inhibiting inositol monophosphatase. J Cell Biol. 2005;170:1101-11 pubmed |
- western blot; mouse; 1:500; fig 3
| Wong H, Fricker M, Wyttenbach A, Villunger A, Michalak E, Strasser A, et al. Mutually exclusive subsets of BH3-only proteins are activated by the p53 and c-Jun N-terminal kinase/c-Jun signaling pathways during cortical neuron apoptosis induced by arsenite. Mol Cell Biol. 2005;25:8732-47 pubmed |
- western blot; rat; 0.1 ug/ml
| Bu L, Lephart E. Soy isoflavones modulate the expression of BAD and neuron-specific beta III tubulin in male rat brain. Neurosci Lett. 2005;385:153-7 pubmed |
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| Rodolfo C, Mormone E, Matarrese P, Ciccosanti F, Farrace M, Garofano E, et al. Tissue transglutaminase is a multifunctional BH3-only protein. J Biol Chem. 2004;279:54783-92 pubmed |
| Cao J, Semenova M, Solovyan V, Han J, Coffey E, Courtney M. Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death. J Biol Chem. 2004;279:35903-13 pubmed |
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| Kim T, Zhao Y, Ding W, Shin J, He X, Seo Y, et al. Bid-cardiolipin interaction at mitochondrial contact site contributes to mitochondrial cristae reorganization and cytochrome C release. Mol Biol Cell. 2004;15:3061-72 pubmed |
| Watts J, Kline J, Thornton L, Grattan R, Brar S. Metabolic dysfunction and depletion of mitochondria in hearts of septic rats. J Mol Cell Cardiol. 2004;36:141-50 pubmed |
| Soane L, Cho H, Niculescu F, Rus H, Shin M. C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway. J Immunol. 2001;167:2305-11 pubmed |
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| Wagenknecht B, Hermisson M, Groscurth P, Liston P, Krammer P, Weller M. Proteasome inhibitor-induced apoptosis of glioma cells involves the processing of multiple caspases and cytochrome c release. J Neurochem. 2000;75:2288-97 pubmed |
| Zhou H, Li X, Meinkoth J, Pittman R. Akt regulates cell survival and apoptosis at a postmitochondrial level. J Cell Biol. 2000;151:483-94 pubmed |
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| Liu H, Lo C, Jones B, Pradhan Z, Srinivasan A, Valentino K, et al. Inhibition of c-Myc expression sensitizes hepatocytes to tumor necrosis factor-induced apoptosis and necrosis. J Biol Chem. 2000;275:40155-62 pubmed |
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| Liu M, Spremulli L. Interaction of mammalian mitochondrial ribosomes with the inner membrane. J Biol Chem. 2000;275:29400-6 pubmed |
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| Taanman J, Bodnar A, Cooper J, Morris A, Clayton P, Leonard J, et al. Molecular mechanisms in mitochondrial DNA depletion syndrome. Hum Mol Genet. 1997;6:935-42 pubmed |
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| Capaldi R, Halphen D, Zhang Y, Yanamura W. Complexity and tissue specificity of the mitochondrial respiratory chain. J Bioenerg Biomembr. 1988;20:291-311 pubmed |
| Han J, Kim S, Ryu M, Jang Y, Lee M, Ju X, et al. Chloramphenicol Mitigates Oxidative Stress by Inhibiting Translation of Mitochondrial Complex I in Dopaminergic Neurons of Toxin-Induced Parkinson's Disease Model. Oxid Med Cell Longev. 2019;2019:4174803 pubmed publisher |
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| Knickelbein K, Tong J, Chen D, Wang Y, Misale S, Bardelli A, et al. Restoring PUMA induction overcomes KRAS-mediated resistance to anti-EGFR antibodies in colorectal cancer. Oncogene. 2018;37:4599-4610 pubmed publisher |
| Ruiz M, Bégou M, Launay N, Ranea Robles P, Bianchi P, López Erauskin J, et al. OXIDATIVE STRESS AND MITOCHONDRIAL DYNAMICS MALFUNCTION ARE LINKED IN PELIZAEUS-MERZBACHER DISEASE. Brain Pathol. 2017;: pubmed publisher |
| Koh J, Hancock C, Terada S, Higashida K, Holloszy J, Han D. PPARβ Is Essential for Maintaining Normal Levels of PGC-1α and Mitochondria and for the Increase in Muscle Mitochondria Induced by Exercise. Cell Metab. 2017;25:1176-1185.e5 pubmed publisher |
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| Zheng X, He K, Zhang L, Yu J. Crizotinib induces PUMA-dependent apoptosis in colon cancer cells. Mol Cancer Ther. 2013;12:777-86 pubmed publisher |
| Unuma K, Aki T, Matsuda S, Funakoshi T, Yoshida K, Uemura K. Inducer of heme oxygenase-1 cobalt protoporphyrin accelerates autophagy and suppresses oxidative damages during lipopolysaccharide treatment in rat liver. Hepatol Res. 2013;43:91-6 pubmed publisher |
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| Grossman G, Watson R, Pauer G, Bollinger K, Hagstrom S. Immunocytochemical evidence of Tulp1-dependent outer segment protein transport pathways in photoreceptor cells. Exp Eye Res. 2011;93:658-68 pubmed publisher |
| Heidler J, Al Furoukh N, Kukat C, Salwig I, Ingelmann M, Seibel P, et al. Nitric oxide-associated protein 1 (NOA1) is necessary for oxygen-dependent regulation of mitochondrial respiratory complexes. J Biol Chem. 2011;286:32086-93 pubmed publisher |
| Lu J, E L, Wang W, Frontera J, Zhu H, Wang W, et al. Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice. J Neurochem. 2011;117:154-63 pubmed publisher |
| Dudgeon C, Wang P, Sun X, Peng R, Sun Q, Yu J, et al. PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01. Mol Cancer Ther. 2010;9:2893-902 pubmed publisher |
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| Niizuma K, Endo H, Nito C, Myer D, Chan P. Potential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemia. Stroke. 2009;40:618-25 pubmed publisher |
| Gupta D, Crosby M, Almasan A, Macklis R. Regulation of CD20 expression by radiation-induced changes in intracellular redox status. Free Radic Biol Med. 2008;44:614-23 pubmed |
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| Pláteník J, Balcar V, Yoneda Y, Mioduszewska B, Buchal R, Hynek R, et al. Apparent presence of Ser133-phosphorylated cyclic AMP response element binding protein (pCREB) in brain mitochondria is due to cross-reactivity of pCREB antibodies with pyruvate dehydrogenase. J Neurochem. 2005;95:1446-60 pubmed |
| Stiburek L, Vesela K, Hansikova H, Pecina P, Tesarova M, Cerna L, et al. Tissue-specific cytochrome c oxidase assembly defects due to mutations in SCO2 and SURF1. Biochem J. 2005;392:625-32 pubmed |
| Shi T, Wang F, Stieren E, Tong Q. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem. 2005;280:13560-7 pubmed |
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