MEKK3 Monoclonal Antibody (D36G5) | Invitrogen A16697 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MEKK3 Monoclonal Antibody (D36G5)

catalog :

A16697

quantity :

100µL

price :

US 309.00

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

D36G5

reactivity :

human

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

MEKK3 Monoclonal Antibody (D36G5)

Catalog # :

A16697

Quantity :

100µL

Price :

US 309.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human

Clone :

D36G5

Isotype :

IgG

Storage :

-20°C

Description :

This gene product is a 626-amino acid polypeptide that is 96.5% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4.6-kb transcript that appears to be ubiquitously expressed. This protein directly regulates the stress-activated protein kinase and extracellular signal-regulated protein kinase pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B-dependent reporter gene, consistent with a role in the SAPK pathway. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Immunogen :

synthetic peptide corresponding to residues surrounding Pro310 of human MEKK3 protein.

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

MAPKKK3, MEKK3, MAP/ERK kinase kinase 3, MAPK/ERK kinase kinase 3, MEK kinase 3, MEKK 3