Phospho-SHP-2 (Tyr580) Monoclonal Antibody (D66F10) | Invitrogen A16691 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-SHP-2 (Tyr580) Monoclonal Antibody (D66F10)

catalog :

A16691

quantity :

100µL

price :

US 309.00

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

D66F10

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

product information

Product Type :

Antibody

Product Name :

Phospho-SHP-2 (Tyr580) Monoclonal Antibody (D66F10)

Catalog # :

A16691

Quantity :

100µL

Price :

US 309.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human

Clone :

D66F10

Isotype :

IgG

Storage :

-20°C

Description :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Immunogen :

synthetic phosphopeptide corresponding to residues surrounding Tyr580 of human SHP2 protein.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2, PTP-2C, protein tyrosine phosphatase-2, protein-tyrosine phosphatase 1D, protein-tyrosine phosphatase 2C, tyrosine-protein phosphatase non-receptor type 11