NOTCH3 Monoclonal Antibody (D11B8) | Invitrogen A16683 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NOTCH3 Monoclonal Antibody (D11B8)

catalog :

A16683

quantity :

100µL

price :

US 309.00

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

D11B8

reactivity :

human

application :

western blot, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

NOTCH3 Monoclonal Antibody (D11B8)

Catalog # :

A16683

Quantity :

100µL

Price :

US 309.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Species :

Human

Clone :

D11B8

Isotype :

IgG

Storage :

-20°C

Description :

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

Immunogen :

synthetic peptide corresponding to residues surrounding Glu2312 of human Notch3 protein.

Format :

Liquid

Applications w/Dilutions :

Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent

Aliases :

CADASIL, CASIL, Notch homolog 3, neurogenic locus notch homolog protein 3