CaMKII alpha Monoclonal Antibody (D11A10) | Invitrogen A16650 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CaMKII alpha Monoclonal Antibody (D11A10)

catalog :

A16650

quantity :

100µL

price :

US 309.00

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

D11A10

reactivity :

human

application :

western blot

product information

Product Type :

Antibody

Product Name :

CaMKII alpha Monoclonal Antibody (D11A10)

Catalog # :

A16650

Quantity :

100µL

Price :

US 309.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human

Applications :

Western Blot: Assay Dependent

Species :

Human

Clone :

D11A10

Isotype :

IgG

Storage :

-20°C

Description :

Ca2+/Calmodulin-Dependent Protein Kinase II (CaM Kinase II) is a multi-functional calcium and calmodulin-dependent protein kinase that mediates cellular response to a wide variety of intercellular signals (Kennedy, 1998; Schulman and Hanson, 1993). CaM Kinase II has been shown to regulate diverse cellular functions including synaptic plasticity, neurotransmitter synthesis and release, gene expression, ion channel function, carbohydrate metabolism, cytoskeletal function, and Ca2+-homeostasis (Gleason et al., 2003; Soderling, 2000; Hudmon and Schulman, 2002). Phosphorylation of Thr286 on the kinase produces an autonomously active form of CaM Kinase II (Meng et al., 2003; Picciotto et al., 1993). Autophosphorylation of Thr305 inhibits the activity CaM Kinase II. Phosphorylation at this site appears to reduce the association of CaM Kinase II with the PSD andreduces LTP and learning (Elgersma et al., 2002

Immunogen :

synthetic peptide surrounding Val184 of human CaMKII-alpha.

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay Dependent

Aliases :

calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase II alpha-B subunit, calcium/calmodulin-dependent protein kinase type II alpha chain, Calci