NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

antibody

CD33 Monoclonal Antibody (WM53), PerCP

A15804

100 Tests

US 250.00

monoclonal

mouse

PerCP

WM53

The same clone is also sold as:

• ImmuQuest: IQ473
• Novus Biologicals: NBP3-09095
• OriGene: SM1103PT, SM1103PS, SM1103P, SM1103APC, SM1103F, SM1103R
• Abcam: ab206634, ab213050, ab234216
• Exbio: 1F-662-T100, 1P-662-T025, T8-662-T100, 1A-662-T025, PC-662-T025, T8-662-T025, 12-662-C100, A7-662-T100, 1A-662-T100, T9-662-T025, T7-662-T100, A7-662-T025, T9-662-T100, T4-662-T100, 11-662-C025, 11-662-C100, PC-662-T100, 1P-662-T100, 1F-662-T025, T4-662-T025
• BD Biosciences: 555450, 555449, 562492, 561816, 561157, 551378, 561817, 562854, 551377
• Bio-Rad: MCA1271A700, MCA1271SBUV575, MCA1271SBV790, MCA1271SBV570, MCA1271SBV610, MCA1271A700T, MCA1271SBB675, MCA1271SBUV400, MCA1271SBR670, MCA1271SBV670, MCA1271SBV515, MCA1271SBUV510, MCA1271APC, MCA1271SBR715, MCA1271SBR815, MCA1271, MCA1271SBY800, MCA1271F, MCA1271PE, MCA1271SBUV445, MCA1271SBV440, MCA1271SBV475, MCA1271SBY720, MCA1271SBV710, MCA1271SBV760, MCA1271SBUV795, MCA1271GA, MCA1271SBB615, MCA1271SBB810, MCA1271SBB580, MCA1271SBB765, MCA1271A647, MCA1271SBB700, MCA1271SBY605, MCA1271SBR775, MCA1271SBY665, MCA1271SBUV740, MCA1271SBUV605, MCA1271SBY575, MCA1271SBUV665
• BioLegend: 303426, 303435, 983908, 303430, 303444, 303416, 303404, 303406, 303407, 260130, 983906, 260186, 303443, 303433, 983910, 983904, 303417, 303424, 303453, 303434, 303429, 303447, 303448, 303413, 983902, 303422, 303441, 303440, 303427, 303454, 303402, 303432, 303421, 303415, 303450, 303431, 303403, 303408, 303439, 303436, 303414, 303451, 303438, 303452, 303449, 303442, 303445, 303428, 303423, 303437, 303419, 260366, 260192

CD33 Monoclonal Antibody (WM53), PerCP

A15804

100 Tests

US 250.00

Monoclonal

Size-exclusion chromatography

Mouse

Human, Non-human primate

Flow Cytometry: 10 uL/1x10^6 cells

Human, Non-human primate

WM53

IgG1

4 C, store in dark, DO NOT FREEZE!

CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. CD33 is also expressed on, and is a useful marker for, peripheral monocytes. CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias. Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.

Human AML cells

Liquid

Flow Cytometry: 10 uL/1x10^6 cells

CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3