CD53 Monoclonal Antibody (MEM-53), PE | Invitrogen A15769 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD53 Monoclonal Antibody (MEM-53), PE

catalog :

A15769

quantity :

100 tests

price :

US 227

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

MEM-53

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD53 Monoclonal Antibody (MEM-53), PE

Catalog # :

A15769

Quantity :

100 tests

Price :

US 227

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: Assay Dependent

Species :

Human

Clone :

MEM-53

Isotype :

IgG1

Storage :

4° C

Description :

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumor cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.

Immunogen :

Human CD53

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: Assay Dependent

Aliases :

AI323659; antigen MOX44 identified by monoclonal antibody MRC-OX44; CD53; CD53 antigen; CD53 glycoprotein; CD53 molecule; CD53 tetraspan antigen; cell surface antigen; cell surface glycoprotein CD53; Leukocyte antigen MRC OX-44; leukocyte surface antigen CD53; MOX44; OX44; Ox-44; Tetraspanin-25; transmembrane glycoprotein; TSPAN25; tspan-25