E-cadherin Monoclonal Antibody (67A4), FITC | Invitrogen A15757 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

E-cadherin Monoclonal Antibody (67A4), FITC

catalog :

A15757

quantity :

100 Tests

price :

US 203.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

67A4

reactivity :

human

application :

immunocytochemistry, flow cytometry

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:100; loading ...; fig s12b, s12a immunocytochemistry; human; 1:100; loading ...; fig s1d	Liu Y, Xue M, Du S, Feng W, Zhang K, Zhang L, et al. Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT. Nat Commun. 2019;10:1637 pubmed publisher
immunocytochemistry; human; 1:100; loading ...; fig 4a	Cirillo N, Hassona Y, Celentano A, Lim K, Manchella S, Parkinson E, et al. Cancer-associated fibroblasts regulate keratinocyte cell-cell adhesion via TGF-Î²-dependent pathways in genotype-specific oral cancer. Carcinogenesis. 2017;38:76-85 pubmed publisher
	Kutova O, Sencha L, Pospelov A, Dobrynina O, Brilkina A, Cherkasova E, et al. Comparative Analysis of Cell-Cell Contact Abundance in Ovarian Carcinoma Cells Cultured in Two- and Three-Dimensional In Vitro Models. Biology (Basel). 2020;9: pubmed publisher

product information

Product Type :

Antibody

Product Name :

E-cadherin Monoclonal Antibody (67A4), FITC

Catalog # :

A15757

Quantity :

100 Tests

Price :

US 203.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human

Applications :

Flow Cytometry: 20 uL/1x10^6 cells

Species :

Human

Clone :

67A4

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

Immunogen :

T-47D cells

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 20 uL/1x10^6 cells

Aliases :

AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin

more info or order :

Invitrogen product webpage