CD81 Monoclonal Antibody (M38), FITC | Invitrogen A15753 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD81 Monoclonal Antibody (M38), FITC

catalog :

A15753

quantity :

100 Tests

price :

US 203.00

clonality :

monoclonal

host :

mouse

conjugate :

FITC

clone name :

M38

reactivity :

human, cat

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig 8c	Bagashev A, Sotillo E, Tang C, Black K, Perazzelli J, Seeholzer S, et al. CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum. Mol Cell Biol. 2018;38: pubmed publisher
	Benke M, Ze xf6 ld A, Kittel x, Khamari D, Hritz I, Horv xe1 th M, et al. MiR-200b categorizes patients into pancreas cystic lesion subgroups with different malignant potential. Sci Rep. 2023;13:19820 pubmed publisher
	Bernuz M, Pallar xe8 s Rusi xf1 ol A, Rossi R, Fern xe1 ndez Senac C, Mart xed M, Pividori M. Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications. Methods Mol Biol. 2023;2668:257-276 pubmed publisher
	Malik S, Saltzman W, Bahal R. Extracellular vesicles mediated exocytosis of antisense peptide nucleic acids. Mol Ther Nucleic Acids. 2021;25:302-315 pubmed publisher
	Szvicsek Z, Oszvald Á, Szabó L, Sándor G, Kelemen A, Soós A, et al. Extracellular vesicle release from intestinal organoids is modulated by Apc mutation and other colorectal cancer progression factors. Cell Mol Life Sci. 2019;76:2463-2476 pubmed publisher
	Perge P, Butz H, Pezzani R, Bancos I, Nagy Z, Pálóczi K, et al. Evaluation and diagnostic potential of circulating extracellular vesicle-associated microRNAs in adrenocortical tumors. Sci Rep. 2017;7:5474 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD81 Monoclonal Antibody (M38), FITC

Catalog # :

A15753

Quantity :

100 Tests

Price :

US 203.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Feline, Human, Rabbit

Applications :

Flow Cytometry: 20 uL/1x10^6 cells

Species :

Feline, Human, Rabbit

Clone :

M38

Isotype :

IgG1

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. Like members of the tetraspanin family that include CD9, CD37, CD53, CD63, and CD82, CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that is known to complex with integrins. CD81 appears to promote muscle cell fusion and support myotube maintenance. CD81 associates with CD19, CD21, Leu 13, and integrins on cell membrane and acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. CD81 is also localized in the tumor-suppressor gene region and is a candidate gene for malignancies.

Immunogen :

MOLT-4 (human T-ALL cell line)

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 20 uL/1x10^6 cells

Aliases :

26 kDa cell surface protein TAPA-1; CD 81 antigen; Cd81; CD81 antigen; CD81 antigen (target of antiproliferative antibody 1); CD81 molecule; CVID6; S5.7; Tapa1; Tapa-1; Target of the antiproliferative antibody 1; Tetraspanin28; tetraspanin-28; Tspan28; Tspan-28

more info or order :

Invitrogen product webpage