P-Selectin Monoclonal Antibody (AK4), APC | Invitrogen A15728 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

P-Selectin Monoclonal Antibody (AK4), APC

catalog :

A15728

quantity :

100 Tests

price :

US 257.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

AK4

The same clone is also sold as:

Exbio: T8-667-T100, 1B-667-C025, 11-667-C100, 1P-667-T100, 1F-667-T025, 11-667-C025, 1B-667-C100, 1F-667-T100, 1A-667-T100, 1P-667-T025, 1A-667-T025, T8-667-T025, 12-667-C100
Santa Cruz Biotechnology: sc-19996, sc-19996 L
BioLegend: 304941, 304928, 304926, 260362, 304951, 304925, 304929, 304910, 304908, 304947, 986404, 304937, 260364, 304903, 304945, 304924, 986402, 304914, 304943, 304931, 304935, 304906, 304927, 304942, 304940, 304933, 304902, 304939, 304916, 304905, 304930, 304936, 304922, 304920, 304904, 304938, 304918, 304948, 304949, 304932, 304944, 304921, 304919
BD Biosciences: 555522, 551345, 555523, 550888, 555524
OriGene: AM26020BT-N, AM26020PU-N, AM26020AC-N, AM26020FC-N, AM26020RP-N, AM26020LE-N

reactivity :

human

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

P-Selectin Monoclonal Antibody (AK4), APC

Catalog # :

A15728

Quantity :

100 Tests

Price :

US 257.00

Clonality :

Monoclonal

Purity :

Size-exclusion chromatography

Host :

Mouse

Reactivity :

Human, Non-human primate

Applications :

Flow Cytometry: 10 uL/1x10^6 cells

Species :

Human, Non-human primate

Clone :

AK4

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. From there, it can be rapidly brought to the cell surface after exposure to thrombin, histamine, complement 5a, Ca21 ionophores, or adenosine diphosphate. P-selectin protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. P-selectin plays an important role in adhesive processes between leucocytes and endothelial cells, and is a calcium dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens found on neutrophils and monocytes. P-selectin is constitutively expressed in inflammation and contributes to atherogenesis, thrombosis and tissue destruction. Clinically, P-selectin is used to distinguish heparin induced thrombocytopenia with and without thrombosis.

Immunogen :

Human platelets

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 10 uL/1x10^6 cells

Aliases :

CD62; CD62 antigen-like family member P; CD62P; CD62P antigen; CD62P; CD62 homolog; FLJ45155; GMP140; GMP-140; GMRP; Granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; Grmp; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; Platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; PSELECT; P-selectin; P-selectin precursor; RP1-86F14.2; selectin P; selectin P (granule membrane protein 140kDa, antigen CD62); selectin, platelet; Selp