CD14 Monoclonal Antibody (61D3), APC-Cyanine7 | Invitrogen A15453 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD14 Monoclonal Antibody (61D3), APC-Cyanine7

catalog :

A15453

quantity :

100 ug

price :

US 443.00

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

61D3

reactivity :

crab eating macaque, human, dogs

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s14b	Poletto E, Colella P, Pimentel Vera L, Khan S, Tomatsu S, Baldo G, et al. Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation. Mol Ther Methods Clin Dev. 2022;25:392-409 pubmed publisher
flow cytometry; human; loading ...; fig 2a	Liu Q, Ou Q, Chen H, Gao Y, Liu Y, Xu Y, et al. Differential expression and predictive value of monocyte scavenger receptor CD163 in populations with different tuberculosis infection statuses. BMC Infect Dis. 2019;19:1006 pubmed publisher
flow cytometry; human; loading ...; fig s3a	Taylor J, Cash M, Santostefano K, Nakanishi M, Terada N, Wallet M. CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages. J Leukoc Biol. 2018;: pubmed publisher
flow cytometry; human; loading ...; fig s1a	Lopes F, BÃ¡lint Å, Valvo S, Felce J, Hessel E, Dustin M, et al. Membrane nanoclusters of FcÎ³RI segregate from inhibitory SIRPÎ± upon activation of human macrophages. J Cell Biol. 2017;216:1123-1141 pubmed publisher
flow cytometry; human; 1:5; loading ...	Lu X, Chen Q, Rong Y, Yang G, Li C, Xu N, et al. LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells. Nat Commun. 2016;7:12719 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CD14 Monoclonal Antibody (61D3), APC-Cyanine7

Catalog # :

A15453

Quantity :

100 ug

Price :

US 443.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Canine, Cynomolgus Monkey, Human

Applications :

Flow Cytometry: 10 uL/1x10^6 cells

Species :

Canine, Cynomolgus Monkey, Human

Clone :

61D3

Isotype :

IgG1, kappa

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

CD14 is a 55 kDa GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils. CD14 also serves as a multifunctional lipopolysaccharide receptor, and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Alternative splicing results in multiple transcript variants encoding the same CD14 isoform. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and Croup.

Immunogen :

Human CD14 from Human peripheral monocytes

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 10 uL/1x10^6 cells

Aliases :

CD 14; CD14; CD14 antigen; CD14 molecule; cd14 monocyte; lipopolysaccharide receptor; lipoprotein receptor; LPSR antibody; monocyte differentiation antigen CD14; Monocyte differentiation antigen CD14, membrane-bound form; Monocyte differentiation antigen CD14, urinary form; monocyte differentiation antigen CD14; LOW QUALITY PROTEIN: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein; myeloid membrane glycoprotein precursor; sCD14; soluble CD14

more info or order :

Invitrogen product webpage