TCR beta Monoclonal Antibody (H57-597), PE-Cyanine5.5 | Invitrogen A15410 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TCR beta Monoclonal Antibody (H57-597), PE-Cyanine5.5

catalog :

A15410

quantity :

100 ug

price :

US 374.00

clonality :

monoclonal

host :

hamsters

conjugate :

PE-Cy5.5

clone name :

H57-597

The same clone is also sold as:

Exbio: 12-571-C100, 11-571-C100
Rockland Immunochemicals: 200-B08-N92, 200-B02-N92, 200-B26-N92
BioLegend: 109231, 109246, 109238, 109206, 109221, 109216, 109251, 109227, 109201, 109207, 109218, 109230, 109243, 109265, 109233, 109261, 109211, 109224, 109247, 109256, 109225, 109235, 109254, 109241, 109208, 109263, 109217, 109245, 109234, 285073, 109220, 109223, 109258, 109202, 109219, 109209, 109259, 109204, 109255, 109222, 109229, 109249, 109226, 109264, 109228, 109203, 109210, 109215, 109212, 109239, 109205, 109253, 109257, 109240

reactivity :

mouse

application :

flow cytometry

citations: 1

Reference
Jandl C, Liu S, Canete P, Warren J, Hughes W, Vogelzang A, et al. IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2. Nat Commun. 2017;8:14647 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TCR beta Monoclonal Antibody (H57-597), PE-Cyanine5.5

Catalog # :

A15410

Quantity :

100 ug

Price :

US 374.00

Clonality :

Monoclonal

Purity :

purified

Host :

Armenian Hamster

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.2 ug/1x10^6 cells

Species :

Mouse

Clone :

H57-597

Isotype :

IgG2

Storage :

4 C, store in dark, DO NOT FREEZE!

Description :

The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5). T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). A small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.

Immunogen :

TCR affinity purified from mouse T cell hybridoma DO-11.101

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.2 ug/1x10^6 cells

Aliases :

bTCR; FLJ22602; MGC117436; MGC22624; MGC23964; MGC71411; T cell receptor beta chain; t-cell antigen receptor; T-cell receptor; TCR beta; Tcra; Tcrb; TCRbeta; TCRD; Tib; TRA