This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TCR gamma/delta Monoclonal Antibody (UC7-13D5), FITC
catalog :
A15406
quantity :
100 ug
price :
US 377.00
clonality :
monoclonal
host :
hamsters
conjugate :
FITC
clone name :
UC7-13D5

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
TCR gamma/delta Monoclonal Antibody (UC7-13D5), FITC
Catalog # :
A15406
Quantity :
100 ug
Price :
US 377.00
Clonality :
Monoclonal
Purity :
purified
Host :
Armenian Hamster
Reactivity :
Mouse
Applications :
Flow Cytometry: 1 ug/1x10^6 cells
Species :
Mouse
Clone :
UC7-13D5
Isotype :
IgG3
Storage :
4 C, store in dark
Description :
TCR gamma/delta (T-cell receptor gamma/delta) are specialized T-cells in the immune system. The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response. TCR recognition of self-peptides has been linked to autoimmune disease. Mutant self-peptides have been associated with tumors. Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome. Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The autoantibodies block TH1-mediated inflammatory auto-destructive reactions and are believed to be a method by which the immune system compensates for disease. Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP). However, a small number of T cells lack both CD4 and CD8 (double negative, DN). Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders. Gamma-delta T cells are primarily found within the epithelium. They show less TCR diversity and recognize antigens differently than alpha-beta T cells. Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
Immunogen :
This Armenian hamster IgG is specific to the -gamma -delta T-cell receptor (TCR) complex.
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1 ug/1x10^6 cells
Aliases :
RGD1311300; similar to T cell receptor V delta 6; T cell receptor gamma locus; T3/TCR complex; TCR delta gamma; TCR gamma/delta; TCR-CD3 complex; Tcrg; Trg; Trg@
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA