This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-10 Monoclonal Antibody (JES5-16E3), FITC
catalog :
A15376
quantity :
100 ug
price :
US 253.00
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
JES5-16E3

The same clone is also sold as:
reactivity :
mouse
application :
flow cytometry
citations: 1
Reference
Bjarnadóttir K, Benkhoucha M, Merkler D, Weber M, Payne N, Bernard C, et al. B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation. Sci Rep. 2016;6:34594 pubmed publisher
product information
Product Type :
Antibody
Product Name :
IL-10 Monoclonal Antibody (JES5-16E3), FITC
Catalog # :
A15376
Quantity :
100 ug
Price :
US 253.00
Clonality :
Monoclonal
Purity :
purified
Host :
Rat
Reactivity :
Mouse
Applications :
ELISA: 1 ug/10^6 cells, Flow Cytometry: 1 ug/1x10^6 cells
Species :
Mouse
Clone :
JES5-16E3
Isotype :
IgG2b, kappa
Storage :
4 C, store in dark
Description :
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
Immunogen :
E. coli-expressed recombinant mouse IL-10 from E. coli-expressed mouse IL-10
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/10^6 cells, Flow Cytometry: 1 ug/1x10^6 cells
Aliases :
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA