This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Bcl-xL Monoclonal Antibody (7B2.5), Biotin
catalog :
A15375
quantity :
100 ug
price :
US 460.00
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
7B2.5

The same clone is also sold as:
reactivity :
human, mouse, rat, rhesus macaque
application :
flow cytometry
product information
Product Type :
Antibody
Product Name :
Bcl-xL Monoclonal Antibody (7B2.5), Biotin
Catalog # :
A15375
Quantity :
100 ug
Price :
US 460.00
Clonality :
Monoclonal
Purity :
purified
Host :
Mouse
Reactivity :
Human, Mouse, Rat, Rhesus Monkey
Applications :
Flow Cytometry: 3 ug/1x10^6 cells
Species :
Human, Mouse, Rat, Rhesus Monkey
Clone :
7B2.5
Isotype :
IgG3, kappa
Storage :
4 C
Description :
BCL-XL is a part of the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL-XL is located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential and controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Immunogen :
Recombinant Bcl-xS from Recombinant human Bcl-xS
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 3 ug/1x10^6 cells
Aliases :
anti-apoptosis regulatory protein; apoptosis regulator Bcl-X; B cell lymphoma 2 like; B cell lymphoma like X; B-cell leukemia/lymphoma x; Bcl(X)L; BCL2 like 1; Bcl2l; BCL2L1; bcl2-L-1; BCL2-like 1; Bcl-2-like protein 1; BCLX; bcl-x; BCLXL; Bcl-XL; BCL-XL/S; BCLXS; bcl-xS; Blc2l; DKFZp781P2092; EGK_02534; OTTHUMP00000030550; OTTHUMP00000030552; OTTHUMP00000030555; OTTHUMP00000030556; OTTHUMP00000030557; PPP1R52; protein phosphatase 1, regulatory subunit 52; RP5-857M17.3
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA