CD45.2 Monoclonal Antibody (104), Alexa Fluor 647 | Invitrogen A14737 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD45.2 Monoclonal Antibody (104), Alexa Fluor 647

catalog :

A14737

quantity :

25 ug

price :

US 163.00

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

104

The same clone is also sold as:

BioLegend: 109837, 109827, 109836, 109847, 109819, 285023, 109803, 109813, 109862, 109818, 109851, 109829, 109831, 109857, 109843, 109830, 109825, 109853, 109835, 109821, 109822, 109863, 109824, 109807, 109859, 109823, 109861, 109850, 109868, 109867, 285018, 109802, 109805, 109839, 109826, 109815, 109806, 109845, 109855, 109817, 109816, 109852, 109838, 109828, 109846, 109832, 109814, 109864, 109808, 109804, 109841, 109820, 109833
Abcam: ab210184, ab210187
OriGene: AM08063C5-N, AM08063BT-N, AM08063RP-N, AM08063FC-N, AM08063AC5-N, AM08063PU-N, AM08063RC7-N, AM08063RC5-N
BD Biosciences: 552950, 561874, 561875, 558702, 553772, 562129, 553771, 560697, 564616, 560693, 560695, 560694, 740490, 560696, 562130, 563685
Tonbo Biosciences: 65-0454
Rockland Immunochemicals: 200-326-N86, 200-308-N86, 200-302-N86

reactivity :

mouse

application :

flow cytometry

product information

Product Type :

Antibody

Product Name :

CD45.2 Monoclonal Antibody (104), Alexa Fluor 647

Catalog # :

A14737

Quantity :

25 ug

Price :

US 163.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Mouse

Applications :

Flow Cytometry: 0.3 ug/1x10^6 cells

Species :

Mouse

Clone :

104

Isotype :

IgG2a, kappa

Storage :

4 C, store in dark

Description :

CD45.2 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes. CD45.2 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases. CD45.2 protein exists as multiple isoforms as a result of alternative splicing; these isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. Besides the role in immunoreceptor signaling, CD45.2 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells.

Immunogen :

B10.S mouse thymocytes and splenocytes.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 0.3 ug/1x10^6 cells

Aliases :

B220; Cd45; CD45 antigen; CD45R; GP180; LCA; L-CA; leukocyte common antigen; loc; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; protein tyrosine phosphatase, receptor type, C; Ptprc; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein