OCT4 Monoclonal Antibody (C30A3) | Invitrogen A13998 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

OCT4 Monoclonal Antibody (C30A3)

catalog :

A13998

quantity :

100µL

price :

US 299.00

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

C30A3

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:400; loading ...; fig s1	Aguisanda F, Yeh C, Chen C, Li R, Beers J, Zou J, et al. Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics. Orphanet J Rare Dis. 2017;12:120 pubmed publisher
immunocytochemistry; human; 1:2500; fig s1 western blot; human; 1:1000	Fang D, Yan S, Yu Q, Chen D, Yan S. Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons. Sci Rep. 2016;6:31462 pubmed publisher
immunocytochemistry; human; 1:100; loading ...; fig 1d	Long Y, Xu M, Li R, Dai S, Beers J, Chen G, et al. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Transl Med. 2016;5:1644-1655 pubmed
immunocytochemistry; mouse; 1:50	Mallol A, PiquÃ© L, SantalÃ³ J, IbÃ¡Ã±ez E. Morphokinetics of cloned mouse embryos treated with epigenetic drugs and blastocyst prediction. Reproduction. 2016;151:203-14 pubmed publisher
immunocytochemistry; human; 1:100; fig 1	Alves C, Dariolli R, Jorge F, Monteiro M, Maximino J, Martins R, et al. Gene expression profiling for human iPS-derived motor neurons from sporadic ALS patients reveals a strong association between mitochondrial functions and neurodegeneration. Front Cell Neurosci. 2015;9:289 pubmed publisher
immunocytochemistry; human; 1:500; fig 4 western blot; human; 1:500; fig 2	Sun D, Liao G, Liu K, Jian H. Endosialinâ€‘expressing bone sarcoma stemâ€‘like cells are highly tumorâ€‘initiating and invasive. Mol Med Rep. 2015;12:5665-70 pubmed publisher
	Quintanilla R. Cellular characterization of human pluripotent stem cells. Methods Mol Biol. 2013;997:179-90 pubmed publisher

product information

Product Type :

Antibody

Product Name :

OCT4 Monoclonal Antibody (C30A3)

Catalog # :

A13998

Quantity :

100µL

Price :

US 299.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:600, Immunofluorescence: 1:400, Western Blot: 1:1,000

Species :

Human, Mouse

Clone :

C30A3

Isotype :

IgG

Storage :

-20°C

Description :

POU5F1, also commonly known as Oct-4, is a maternally expressed octamer-binding protein that was the first transcription factor described for the early stages of development. The role of POU5F1 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing POU5F1, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.

Immunogen :

Recombinant protein specific to the amino terminus of human Oct-4A

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:600, Immunofluorescence: 1:400, Western Blot: 1:1,000

Aliases :

Oct-3, Oct-4, OCT3, OCT4, OTF-3, OTF3, OTF4, POU domain transcription factor OCT4, POU5F1, Homo sapiens POU class 5 homeobox 1 transcript variant 1, DADB-104B20.2, OTF-3, OTF3, OTF4, POU-type homeodomain-containing DNA-binding protein, octamer-binding protein 3, octamer-binding protein 4, octamer-binding transcription factor 3, octamer-binding transcription factor-3