SCD1 Monoclonal Antibody (C12H5) | Invitrogen A13996 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SCD1 Monoclonal Antibody (C12H5)

catalog :

A13996

quantity :

100µL

price :

US 309.00

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

C12H5

reactivity :

mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 1

Reference
Stein S, Lemos V, Xu P, Demagny H, Wang X, Ryu D, et al. Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease. J Clin Invest. 2017;127:583-592 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SCD1 Monoclonal Antibody (C12H5)

Catalog # :

A13996

Quantity :

100µL

Price :

US 309.00

Clonality :

Monoclonal

Purity :

purified

Host :

Rabbit

Reactivity :

Mouse

Applications :

Immunofluorescence: 1:100, Immunohistochemistry: 1:200, Immunoprecipitation: Assay Dependent, Western Blot: 1:1,000

Species :

Mouse

Clone :

C12H5

Isotype :

IgG

Storage :

-20°C

Description :

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999); Wang et al., 2005).

Immunogen :

Synthetic peptide corresponding to residues surrounding Leu35 of mouse SCD1.

Format :

Liquid

Applications w/Dilutions :

Immunofluorescence: 1:100, Immunohistochemistry: 1:200, Immunoprecipitation: Assay Dependent, Western Blot: 1:1,000

Aliases :

OTTHUMP00000020280, acyl-CoA desaturase, delta(9)-desaturase, delta-9-desaturase, fatty acid desaturase, predicted protein of HQ0998, stearoyl-CoA desaturase opposite strand