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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NMDAR2A Polyclonal Antibody
catalog :
A-6473
quantity :
10µg
price :
US 439
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5d
Sclip A, Sudhof T. LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:500; fig 2
Lie E, Ko J, Choi S, Roh J, Cho Y, Noh R, et al. SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion. Nat Commun. 2016;7:12328 pubmed publisher
  • western blot; mouse; 1:500
Sceniak M, Lang M, Enomoto A, James Howell C, Hermes D, Katz D. Mechanisms of Functional Hypoconnectivity in the Medial Prefrontal Cortex of Mecp2 Null Mice. Cereb Cortex. 2016;26:1938-1956 pubmed publisher
Yakoub A, Sadek M. Development and Characterization of Human Cerebral Organoids: An Optimized Protocol. Cell Transplant. 2018;27:393-406 pubmed publisher
Lisek M, Ferenc B, Studzian M, Pulaski L, Guo F, Zylinska L, et al. Glutamate Deregulation in Ketamine-Induced Psychosis-A Potential Role of PSD95, NMDA Receptor and PMCA Interaction. Front Cell Neurosci. 2017;11:181 pubmed publisher
Ma Q, Ying M, Sui X, Zhang H, Huang H, Yang L, et al. Chronic copper exposure causes spatial memory impairment, selective loss of hippocampal synaptic proteins, and activation of PKR/eIF2α pathway in mice. J Alzheimers Dis. 2015;43:1413-27 pubmed publisher
product information
Product Type :
Antibody
Product Name :
NMDAR2A Polyclonal Antibody
Catalog # :
A-6473
Quantity :
10µg
Price :
US 439
Clonality :
Polyclonal
Purity :
IgG fraction
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: Assay Dependent, Immunofluorescence: 1:500-1:5000, Immunohistochemistry (Frozen): 1:500-1:5000, Immunoprecipitation: 3 µL, Western Blot: 1:100-1:500
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen :
Fusion protein containing amino acid residues 1253–1391 of the C-terminal region of rat brain subunit 2A
Format :
Lyophilized
Applications w/Dilutions :
ELISA: Assay Dependent, Immunofluorescence: 1:500-1:5000, Immunohistochemistry (Frozen): 1:500-1:5000, Immunoprecipitation: 3 µL, Western Blot: 1:100-1:500
Aliases :
EPND; FESD; GluN2A; GluRepsilon1; Glutamate [NMDA] receptor subunit epsilon-1; glutamate ionotropic receptor NMDA type subunit 2A; glutamate receptor; Glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, NMDA2A (epsilon 1); glutamate receptor, ionotropic, N-methyl D-aspartate 2A; Grin2a; hNR2A; LKS; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NR2A; OTTHUMP00000160135; OTTHUMP00000174531
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA