Synapsin 1 Polyclonal Antibody | Invitrogen A-6442 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Synapsin 1 Polyclonal Antibody

catalog :

A-6442

quantity :

10 µg

price :

US 259.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:50; fig 5b	Mazzulli J, Zunke F, Tsunemi T, Toker N, Jeon S, Burbulla L, et al. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. J Neurosci. 2016;36:7693-706 pubmed publisher
immunohistochemistry; rat; 1:200; fig 4 immunocytochemistry; human; 1:200; fig 4	Gunewardene N, Crombie D, Dottori M, Nayagam B. Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived Neurons In Vitro. Stem Cells Int. 2016;2016:1781202 pubmed publisher
	Evans H, Benetatos J, van Roijen M, Bodea L, Götz J. Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling. EMBO J. 2019;38:e101174 pubmed publisher
	Milesi C, Alberici P, Pozzi B, Oldani A, Beznoussenko G, Raimondi A, et al. Redundant and nonredundant organismal functions of EPS15 and EPS15L1. Life Sci Alliance. 2019;2: pubmed publisher
	Driscoll N, Richardson A, Maleski K, Anasori B, Adewole O, Lelyukh P, et al. Two-Dimensional Ti3C2 MXene for High-Resolution Neural Interfaces. ACS Nano. 2018;12:10419-10429 pubmed publisher
	Zunke F, Moise A, Belur N, Gelyana E, Stojkovska I, Dzaferbegovic H, et al. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron. 2018;97:92-107.e10 pubmed publisher
	Paolicelli R, Jawaid A, Henstridge C, Valeri A, Merlini M, Robinson J, et al. TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss. Neuron. 2017;95:297-308.e6 pubmed publisher
	Struzyna L, Wolf J, Mietus C, Adewole D, Chen H, Smith D, et al. Rebuilding Brain Circuitry with Living Micro-Tissue Engineered Neural Networks. Tissue Eng Part A. 2015;21:2744-56 pubmed publisher
	Coyle D, Li J, Baccei M. Regional differentiation of retinoic acid-induced human pluripotent embryonic carcinoma stem cell neurons. PLoS ONE. 2011;6:e16174 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Synapsin 1 Polyclonal Antibody

Catalog # :

A-6442

Quantity :

10 µg

Price :

US 259.00

Clonality :

Polyclonal

Purity :

IgG fraction

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:500-1:5,000, Immunohistochemistry (Frozen): 1:500-1:5,000, Western Blot: 1:500-1:1,000

Species :

Bovine, Human, Mouse, Rat

Isotype :

IgG

Storage :

-20°C

Description :

SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Immunogen :

Purified bovine brain Synapsin 1

Format :

Lyophilized

Applications w/Dilutions :

Immunocytochemistry: 1:500-1:5,000, Immunohistochemistry (Frozen): 1:500-1:5,000, Western Blot: 1:500-1:1,000

Aliases :

Brain protein 4.1; SYN1; Syn-1; SYN1a; SYN1b; Syn1-S; synapsin 1; synapsin I; synapsin Ia; synapsin Ib; synapsin-1; SYNI; truncated synapsin 1-S

more info or order :

Invitrogen product webpage