ATPIF1 Monoclonal Antibody (5E2D7) | Invitrogen A-21355 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ATPIF1 Monoclonal Antibody (5E2D7)

catalog :

A-21355

quantity :

100 µg

price :

US 339.00

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5E2D7

reactivity :

African green monkey, human, mouse, rat, dogs, bovine

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 6a	Xing M, Peterman M, Davis R, Oegema K, Shiau A, Field S. GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. Mol Biol Cell. 2016;27:3828-3840 pubmed
immunocytochemistry; dogs; 1:300; loading ...; fig 2b	Das A, Nag S, Mason A, BARROSO M. Endosome-mitochondria interactions are modulated by iron release from transferrin. J Cell Biol. 2016;214:831-45 pubmed publisher
immunohistochemistry - paraffin section; bovine; fig 2	Rigoglio N, Fátima L, Hanassaka J, Pinto G, Machado A, Gimenes L, et al. Equine chorionic gonadotropin alters luteal cell morphologic features related to progesterone synthesis. Theriogenology. 2013;79:673-9 pubmed publisher
western blot; African green monkey	Baird N, York J, Nunberg J. Arenavirus infection induces discrete cytosolic structures for RNA replication. J Virol. 2012;86:11301-10 pubmed
immunohistochemistry - paraffin section; mouse; 1:1000; fig 1	Lauritzen K, Cheng C, Wiksen H, Bergersen L, Klungland A. Mitochondrial DNA toxicity compromises mitochondrial dynamics and induces hippocampal antioxidant defenses. DNA Repair (Amst). 2011;10:639-53 pubmed publisher
	Sharanek A, Burban A, Laaper M, Heckel E, Joyal J, Soleimani V, et al. OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation. Nat Commun. 2020;11:4116 pubmed publisher
	Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, et al. Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. JCI Insight. 2018;3: pubmed publisher
	Nakamura J, Fujikawa M, Yoshida M. IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice. Biosci Rep. 2013;33: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ATPIF1 Monoclonal Antibody (5E2D7)

Catalog # :

A-21355

Quantity :

100 µg

Price :

US 339.00

Clonality :

Monoclonal

Purity :

purified

Host :

Mouse

Reactivity :

Bovine, Human, Mouse, Rat

Applications :

Immunocytochemistry: 1-5 µg/mL, Western Blot: 1 µg/mL

Species :

Bovine, Human, Mouse, Rat

Clone :

5E2D7

Isotype :

IgG1, kappa

Storage :

4° C

Description :

Complex V, also called F1F0 ATPase or ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP + phosphate to ATP, in oxidative phosphorylation, and as a proton pumping ATPase. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The enzyme was thought to be localized exclusively to mitochondria; however, it has recently been identified on the plasma membrane of several cell types including hepatocytes where it functions as the HDL receptor, on endothelial cells where it may act as the angiostatin receptor, and on the surface of cancer cells. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits; while the F0 consists of a, b, and c subunits. The enzyme in mammals is composed of 17 subunits, five of which make up the easily detached F1. The remainder subunits are components of two stalk domains and the proton pumping F0 part of the machinery. Two of the subunits of the F0 part are encoded on mitochondrial DNA while the other subunits are nuclearly encoded. Mutations in the mitochondrial-encoded subunits of ATP synthase (Complex V) cause OXPHOS disease.

Immunogen :

Recombinant IF1.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-5 µg/mL, Western Blot: 1 µg/mL

Aliases :

ATP synthase F1 subunit epsilon; ATP synthase inhibitor protein; ATP synthase inhibitory factor subunit 1; Atp5if1; ATPase inhibitor (rat mitochondrial IF1 protein); ATPase inhibitor protein; ATPase inhibitor, mitochondrial; ATPase inhibitory factor 1; ATPase inhibitory factor 1, precursor; ATPI; Atpif1; ATPIP; IF(1); IF1; IF1PA; inhibitor of F(1)F(o)-ATPase; IP

more info or order :

Invitrogen product webpage