This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
secondary antibody
product name :
F(ab')2-Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 647
catalog :
A-21246
quantity :
500 ug
price :
US 238.00
citations: 57
Reference
Baldrighi M, Doreth C, Li Y, Zhao X, Warner E, Chenoweth H, et al. PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models. J Clin Invest. 2023;133: pubmed publisher
Garg R, Endzhievskaya S, Williamson M. B-type Plexins promote the GTPase activity of Ran to affect androgen receptor nuclear translocation in prostate cancer. Cancer Gene Ther. 2023;30:1513-1523 pubmed publisher
Chuntharpursat Bon E, Povstyan O, Ludlow M, Carrier D, Debant M, Shi J, et al. PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Commun Biol. 2023;6:358 pubmed publisher
Jeremiah N, Ferran H, Antoniadou K, De Azevedo K, Nikolic J, Maurin M, et al. RELA tunes innate-like interferon I/III responses in human T cells. J Exp Med. 2023;220: pubmed publisher
Mlynarczyk C, Teater M, Pae J, Chin C, Wang L, Arulraj T, et al. BTG1 mutation yields supercompetitive B cells primed for malignant transformation. Science. 2023;379:eabj7412 pubmed publisher
Hennig P, Di Filippo M, Bilfeld G, Mellett M, Beer H. High p62 expression suppresses the NLRP1 inflammasome and increases stress resistance in cutaneous SCC cells. Cell Death Dis. 2022;13:1077 pubmed publisher
Lee J, Kim W, Park E, Cho J. Neocortical synaptic engrams for remote contextual memories. Nat Neurosci. 2022;: pubmed publisher
Oo J, P xe1 lfi K, Warwick T, Wittig I, Prieto Garcia C, Matkovic V, et al. Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell Rep. 2022;41:111670 pubmed publisher
Muusse T, Lee M, Kim H, Parat M, Nanson J, Kobe B, et al. Flow cytometric reporter assays provide robust functional analysis of signaling complexes. J Biol Chem. 2022;298:102666 pubmed publisher
Prasai B, Haber G, Strub M, Ahn R, Ciemniecki J, Sochacki K, et al. The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells. Nat Commun. 2021;12:3970 pubmed publisher
Deliz Aguirre R, Cao F, Gerpott F, Auevechanichkul N, Chupanova M, Mun Y, et al. MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling. J Cell Biol. 2021;220: pubmed publisher
Brinck Andersen N, Jørgensen S, Skipper K, Larsen S, Heinz J, Thomsen M, et al. Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient. Autophagy. 2020;:1-16 pubmed publisher
Rigon M, Hörner S, Straka T, Bieback K, Gretz N, Hafner M, et al. Effects of ASC Application on Endplate Regeneration Upon Glycerol-Induced Muscle Damage. Front Mol Neurosci. 2020;13:107 pubmed publisher
Zwettler F, Spindler M, Reinhard S, Klein T, Kurz A, Benavente R, et al. Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy. Nat Commun. 2020;11:3222 pubmed publisher
Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al. Spt6 is a maintenance factor for centromeric CENP-A. Nat Commun. 2020;11:2919 pubmed publisher
Lachance V, Wang Q, Sweet E, Choi I, Cai C, Zhuang X, et al. Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. Mol Neurodegener. 2019;14:43 pubmed publisher
Deng Z, Lim J, Wang Q, Purtell K, Wu S, Palomo G, et al. ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway. Autophagy. 2019;:1-15 pubmed publisher
Vivancos Stalin L, Gualandi M, Schulte J, Renella R, Shakhova O, M xfc hlethaler Mottet A. Expression of the Neuroblastoma-Associated ALK-F1174L Activating Mutation During Embryogenesis Impairs the Differentiation of Neural Crest Progenitors in Sympathetic Ganglia. Front Oncol. 2019;9:275 pubmed publisher
Klicks J, Maßlo C, Kluth A, Rudolf R, Hafner M. A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells. BMC Cancer. 2019;19:402 pubmed publisher
Reinkemeier C, Girona G, Lemke E. Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes. Science. 2019;363: pubmed publisher
Gentili M, Lahaye X, Nadalin F, Nader G, Puig Lombardi E, Hervé S, et al. The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus. Cell Rep. 2019;26:2377-2393.e13 pubmed publisher
Lee D, Tan W, Anene Nzelu C, Lee C, Li P, Luu T, et al. Robust CTCF-Based Chromatin Architecture Underpins Epigenetic Changes in the Heart Failure Stress-Gene Response. Circulation. 2019;139:1937-1956 pubmed publisher
Ueda M, El Jurdi N, Cooper B, Caimi P, Baer L, Kolk M, et al. Low-Dose Azacitidine with DNMT1 Level Monitoring to Treat Post-Transplantation Acute Myelogenous Leukemia or Myelodysplastic Syndrome Relapse. Biol Blood Marrow Transplant. 2019;25:1122-1127 pubmed publisher
Keklikoglou I, Cianciaruso C, Güç E, Squadrito M, Spring L, Tazzyman S, et al. Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nat Cell Biol. 2019;21:190-202 pubmed publisher
Cabral J, Oh H, Knipe D. ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress. elife. 2018;7: pubmed publisher
Keller J, Chen J, Simpson S, Wang E, Lilascharoen V, George O, et al. Voluntary urination control by brainstem neurons that relax the urethral sphincter. Nat Neurosci. 2018;21:1229-1238 pubmed publisher
Harrison C, Laubitz D, Ohland C, Midura Kiela M, Patil K, Besselsen D, et al. Microbial dysbiosis associated with impaired intestinal Na+/H+ exchange accelerates and exacerbates colitis in ex-germ free mice. Mucosal Immunol. 2018;11:1329-1341 pubmed publisher
Monguió Tortajada M, Franquesa M, Sarrias M, Borras F. Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes. Cell Death Dis. 2018;9:499 pubmed publisher
Adams S, Maezawa S, Alavattam K, Abe H, Sakashita A, Shroder M, et al. RNF8 and SCML2 cooperate to regulate ubiquitination and H3K27 acetylation for escape gene activation on the sex chromosomes. PLoS Genet. 2018;14:e1007233 pubmed publisher
Löfdahl A, Wenglén C, Rydell Törmänen K, Westergren Thorsson G, Larsson Callerfelt A. Effects of 5-Hydroxytryptamine Class 2 Receptor Antagonists on Bronchoconstriction and Pulmonary Remodeling Processes. Am J Pathol. 2018;188:1113-1119 pubmed publisher
Dambaeva S, Schneiderman S, Jaiswal M, Agrawal V, Katara G, Gilman Sachs A, et al. Interleukin 22 prevents lipopolysaccharide- induced preterm labor in mice. Biol Reprod. 2018;98:299-308 pubmed publisher
Haas K, Lee M, Esposito A, Venkitaraman A. Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites. Nucleic Acids Res. 2018;46:2398-2416 pubmed publisher
Draper J, Sroczynska P, Fadlullah M, Patel R, Newton G, Breitwieser W, et al. A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects. PLoS Genet. 2018;14:e1007127 pubmed publisher
Lund K, Olsen C, Wong J, Olsen P, Solberg N, Høgset A, et al. 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. J Exp Clin Cancer Res. 2017;36:187 pubmed publisher
Pelliccia J, Jindal G, Burdine R. Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning. elife. 2017;6: pubmed publisher
Litteljohn D, Rudyk C, Dwyer Z, Farmer K, Fortin T, Hayley S. The impact of murine LRRK2 G2019S transgene overexpression on acute responses to inflammatory challenge. Brain Behav Immun. 2018;67:246-256 pubmed publisher
Molokie R, Lavelle D, Gowhari M, Pacini M, Krauz L, Hassan J, et al. Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study. PLoS Med. 2017;14:e1002382 pubmed publisher
van Nierop G, van Luijn M, Michels S, Melief M, Janssen M, Langerak A, et al. Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients. Acta Neuropathol. 2017;134:383-401 pubmed publisher
He G, Shi Y, Lim J, Bellido T, Ni J, Long F. Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth. Bone Res. 2017;5:17016 pubmed publisher
Quadrato G, Nguyen T, Macosko E, Sherwood J, Min Yang S, Berger D, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53 pubmed publisher
Pohar J, Yamamoto C, Fukui R, Cajnko M, Miyake K, Jerala R, et al. Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA. J Immunol. 2017;198:2093-2104 pubmed publisher
Froehlich J, Versapuech M, Megrelis L, Largeteau Q, Meunier S, Tanchot C, et al. FAM65B controls the proliferation of transformed and primary T cells. Oncotarget. 2016;7:63215-63225 pubmed publisher
Otsuka K, Suzuki K. Differences in Radiation Dose Response between Small and Large Intestinal Crypts. Radiat Res. 2016;186:302-14 pubmed publisher
Goode D, Obier N, Vijayabaskar M, Lie A Ling M, Lilly A, Hannah R, et al. Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation. Dev Cell. 2016;36:572-87 pubmed publisher
Vedyaykin A, Vishnyakov I, Polinovskaya V, Khodorkovskii M, Sabantsev A. New insights into FtsZ rearrangements during the cell division of Escherichia coli from single-molecule localization microscopy of fixed cells. Microbiologyopen. 2016;5:378-86 pubmed publisher
Liu G, Gradstedt H, Ermert D, Englund E, Singh B, Su Y, et al. Moraxella catarrhalis Evades Host Innate Immunity via Targeting Cartilage Oligomeric Matrix Protein. J Immunol. 2016;196:1249-58 pubmed publisher
Mohammed H, Russell I, Stark R, Rueda O, Hickey T, Tarulli G, et al. Progesterone receptor modulates ERα action in breast cancer. Nature. 2015;523:313-7 pubmed publisher
Sanjurjo L, Amézaga N, Aran G, Naranjo Gómez M, Arias L, Armengol C, et al. The human CD5L/AIM-CD36 axis: A novel autophagy inducer in macrophages that modulates inflammatory responses. Autophagy. 2015;11:487-502 pubmed publisher
Steinmetz B, Hackl H, Slabáková E, Schwarzinger I, Smějová M, Spittler A, et al. The oncogene EVI1 enhances transcriptional and biological responses of human myeloid cells to all-trans retinoic acid. Cell Cycle. 2014;13:2931-43 pubmed publisher
Fitzpatrick P, Shattil S, Ablooglu A. C-terminal COOH of integrin ?1 is necessary for ?1 association with the kindlin-2 adapter protein. J Biol Chem. 2014;289:11183-93 pubmed publisher
Okada T, Nitta T, Kaji K, Takashima A, Oda H, Tamehiro N, et al. Differential function of Themis CABIT domains during T cell development. PLoS ONE. 2014;9:e89115 pubmed publisher
Bondar C, Araya R, Guzmán L, Rua E, Chopita N, Chirdo F. Role of CXCR3/CXCL10 axis in immune cell recruitment into the small intestine in celiac disease. PLoS ONE. 2014;9:e89068 pubmed publisher
Olivier N, Keller D, GONCZY P, Manley S. Resolution doubling in 3D-STORM imaging through improved buffers. PLoS ONE. 2013;8:e69004 pubmed publisher
Jarboui M, Bidoia C, Woods E, Roe B, Wynne K, Elia G, et al. Nucleolar protein trafficking in response to HIV-1 Tat: rewiring the nucleolus. PLoS ONE. 2012;7:e48702 pubmed publisher
Lin W, Inatomi O, Lee C, Kallis Y, Otto W, Jeffery R, et al. Bone marrow-derived cells contribute to cerulein-induced pancreatic fibrosis in the mouse. Int J Exp Pathol. 2012;93:130-8 pubmed publisher
Miyamoto K, Furusawa T, Ohnuki M, Goel S, Tokunaga T, Minami N, et al. Reprogramming events of mammalian somatic cells induced by Xenopus laevis egg extracts. Mol Reprod Dev. 2007;74:1268-77 pubmed
Gavrikov K, Nilson J, Dmitriev A, Zucker C, Mangel S. Dendritic compartmentalization of chloride cotransporters underlies directional responses of starburst amacrine cells in retina. Proc Natl Acad Sci U S A. 2006;103:18793-8 pubmed
product information
Product Type :
Secondary Antibody
Product Name :
F(ab')2-Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 647
Catalog # :
A-21246
Quantity :
500 ug
Price :
US 238.00
Clonality :
Polyclonal
Purity :
purified
Host :
F(ab')2-Goat
Reactivity :
Rabbit
Applications :
Immunocytochemistry: 1:500-1:2,000, Western Blot: 1:5,000-1:10,000
Species :
Rabbit
Isotype :
IgG
Storage :
4 C, store in dark
Description :
Anti-Rabbit secondary antibodies are affinity-purified antibodies with well-characterized specificity for rabbit immunoglobulins and are useful in the detection, sorting or purification of its specified target. Secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody. Most commonly, secondary antibodies are generated by immunizing the host animal with a pooled population of immunoglobulins from the target species and can be further purified and modified (i.e. immunoaffinity chromatography, antibody fragmentation, label conjugation, etc.) to generate highly specific reagents.
Immunogen :
Gamma Immunoglobins Heavy and Light chains
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:500-1:2,000, Western Blot: 1:5,000-1:10,000
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA