product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
secondary antibody
product name :
Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
catalog :
A-11034
quantity :
1 mg
price :
US 239
more info or order :
citations: 561
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; Austrofundulus limnaeus; 1:1000; loading ...; fig 2a
Toni L, Padilla P. Developmentally arrested Austrofundulus limnaeus embryos have changes in post-translational modifications of histone H3. J Exp Biol. 2016;219:544-52 pubmed publisher
Li X, Liu X, Wang Y, Cao F, Chen Z, Hu Z, et al. Intervertebral disc degeneration in mice with type II diabetes induced by leptin receptor deficiency. BMC Musculoskelet Disord. 2020;21:77 pubmed publisher
Polubothu S, McGuire N, Al Olabi L, Baird W, Bulstrode N, Chalker J, et al. Does the gene matter? Genotype-phenotype and genotype-outcome associations in congenital melanocytic naevi. Br J Dermatol. 2020;182:434-443 pubmed publisher
Brydon E, Bronstein R, Buskin A, Lako M, Pierce E, Fernandez Godino R. AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/- iPSC-Derived RPE Cells. Mol Ther Methods Clin Dev. 2019;15:392-402 pubmed publisher
Serçin O, Reither S, Roidos P, Ballin N, Palikyras S, Baginska A, et al. A solid-phase transfection platform for arrayed CRISPR screens. Mol Syst Biol. 2019;15:e8983 pubmed publisher
Laviv T, Scholl B, Parra Bueno P, Foote B, Zhang C, Yan L, et al. In Vivo Imaging of the Coupling between Neuronal and CREB Activity in the Mouse Brain. Neuron. 2019;: pubmed publisher
Scott R, Arostegui M, Schweitzer R, Rossi F, Underhill T. Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration. Cell Stem Cell. 2019;25:797-813.e9 pubmed publisher
Gambardella L, McManus S, Moignard V, Sebukhan D, Delaune A, Andrews S, et al. BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium. Development. 2019;146: pubmed publisher
Chappidi N, Nascakova Z, Boleslavska B, Zellweger R, Isik E, Andrs M, et al. Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Mol Cell. 2019;: pubmed publisher
Sung Y, Jin P, Chu L, Hsu F, Wang M, Chang C, et al. Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies. Nat Nanotechnol. 2019;14:1160-1169 pubmed publisher
Odle R, Walker S, Oxley D, Kidger A, Balmanno K, Gilley R, et al. An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Mol Cell. 2019;: pubmed publisher
Zielinska A, Bellou E, Sharma N, Frombach A, Seres K, Gruhn J, et al. Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs. Curr Biol. 2019;29:3749-3765.e7 pubmed publisher
Woo D, Seo Y, Jung H, Kim S, Kim N, Park S, et al. Locally Activating TrkB Receptor Generates Actin Waves and Specifies Axonal Fate. Cell Chem Biol. 2019;26:1652-1663.e4 pubmed publisher
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, et al. TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering. Cell Rep. 2019;29:1130-1146.e8 pubmed publisher
Grajcarek J, Monlong J, Nishinaka Arai Y, Nakamura M, Nagai M, Matsuo S, et al. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nat Commun. 2019;10:4856 pubmed publisher
Ochs F, Karemore G, Miron E, Brown J, Sedlackova H, Rask M, et al. Stabilization of chromatin topology safeguards genome integrity. Nature. 2019;574:571-574 pubmed publisher
Akieda Y, Ogamino S, Furuie H, Ishitani S, Akiyoshi R, Nogami J, et al. Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo. Nat Commun. 2019;10:4710 pubmed publisher
Schlichting M, Díaz M, Xin J, Rosbash M. Neuron-specific knockouts indicate the importance of network communication to Drosophila rhythmicity. elife. 2019;8: pubmed publisher
Massey J, Chung D, Siwanowicz I, Stern D, Wittkopp P. The yellow gene influences Drosophila male mating success through sex comb melanization. elife. 2019;8: pubmed publisher
Shen A, Chen D, Kaur M, Bartels P, Xu B, Shi Q, et al. β-blockers augment L-type Ca2+ channel activity by targeting spatially restricted β2AR signaling in neurons. elife. 2019;8: pubmed publisher
Bonaventura J, Eldridge M, Hu F, Gomez J, Sánchez Soto M, Abramyan A, et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat Commun. 2019;10:4627 pubmed publisher
Wilson T, Valdivia S, Khan A, Ahn H, Adke A, Martinez Gonzalez S, et al. Dual and Opposing Functions of the Central Amygdala in the Modulation of Pain. Cell Rep. 2019;29:332-346.e5 pubmed publisher
Scheefhals N, Catsburg L, Westerveld M, Blanpied T, Hoogenraad C, MacGillavry H. Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Cell Rep. 2019;29:258-269.e8 pubmed publisher
Antinucci P, Folgueira M, Bianco I. Pretectal neurons control hunting behaviour. elife. 2019;8: pubmed publisher
Stine R, Sakers A, Teslaa T, Kissig M, Stine Z, Kwon C, et al. PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism. Cell Stem Cell. 2019;25:830-845.e8 pubmed publisher
Yu T, Gan S, Zhu Q, Dai D, Li N, Wang H, et al. Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24. Nat Commun. 2019;10:4353 pubmed publisher
Ma Y, Miracca G, Yu X, Harding E, Miao A, Yustos R, et al. Galanin Neurons Unite Sleep Homeostasis and α2-Adrenergic Sedation. Curr Biol. 2019;29:3315-3322.e3 pubmed publisher
Miller D, Lebowitz J, Guenther D, Refowich A, Hansen C, Maurer A, et al. Methamphetamine regulation of activity and topology of ventral midbrain networks. PLoS ONE. 2019;14:e0222957 pubmed publisher
Li J, Shang G, Chen Y, Brautigam C, Liou J, Zhang X, et al. Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands. elife. 2019;8: pubmed publisher
Samir P, Kesavardhana S, Patmore D, Gingras S, Malireddi R, Karki R, et al. DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome. Nature. 2019;573:590-594 pubmed publisher
Hernández Bule M, Medel E, Colastra C, Roldan R, Ubeda A. Response of neuroblastoma cells to RF currents as a function of the signal frequency. BMC Cancer. 2019;19:889 pubmed publisher
Fréal A, Rai D, Tas R, Pan X, Katrukha E, van de Willige D, et al. Feedback-Driven Assembly of the Axon Initial Segment. Neuron. 2019;104:305-321.e8 pubmed publisher
Labzin L, Bottermann M, Rodriguez Silvestre P, Foss S, Andersen J, Vaysburd M, et al. Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection. EMBO J. 2019;38:e101365 pubmed publisher
Sasaki K, Himeno A, Nakagawa T, Sasaki Y, Kiyonari H, Iwai K. Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death. Nat Commun. 2019;10:3878 pubmed publisher
Skrenkova K, Hemelikova K, Kolcheva M, Kortus S, Kaniaková M, Krausova B, et al. Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors. Sci Rep. 2019;9:12303 pubmed publisher
Lindhout F, Cao Y, Kevenaar J, Bodzęta A, Stucchi R, Boumpoutsari M, et al. VAP-SCRN1 interaction regulates dynamic endoplasmic reticulum remodeling and presynaptic function. EMBO J. 2019;:e101345 pubmed publisher
Kondo T, Hayashi S. Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea. elife. 2019;8: pubmed publisher
Pinto C, Khandekar A, Bhavna R, Kiesel P, Pigino G, Sonawane M. Microridges are apical epithelial projections formed of F-actin networks that organize the glycan layer. Sci Rep. 2019;9:12191 pubmed publisher
Martínez J, Tarallo D, Martinez Palma L, Victoria S, Bresque M, Rodriguez Bottero S, et al. Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells. Biochem J. 2019;476:2463-2486 pubmed publisher
Cohen Katsenelson K, Stender J, Kawashima A, Lordén G, Uchiyama S, Nizet V, et al. PHLPP1 counter-regulates STAT1-mediated inflammatory signaling. elife. 2019;8: pubmed publisher
Hill A, Jain P, Folan N, Ben Shahar Y. The Drosophila ERG channel seizure plays a role in the neuronal homeostatic stress response. PLoS Genet. 2019;15:e1008288 pubmed publisher
Soiberman U, Shehata A, Lu M, Young T, Daoud Y, Chakravarti S, et al. Small Molecule Modulation of the Integrated Stress Response Governs the Keratoconic Phenotype In Vitro. Invest Ophthalmol Vis Sci. 2019;60:3422-3431 pubmed publisher
Nichols E, Smith C. Synaptic-like Vesicles Facilitate Pioneer Axon Invasion. Curr Biol. 2019;29:2652-2664.e4 pubmed publisher
Zhovmer A, Tabdanov E, Miao H, Wen H, Chen J, Luo X, et al. The role of nonmuscle myosin 2A and 2B in the regulation of mesenchymal cell contact guidance. Mol Biol Cell. 2019;30:1961-1973 pubmed publisher
Li L, Martin Levilain J, Jiménez Sánchez C, Karaca M, Foti M, Martinou J, et al. In vivo stabilization of OPA1 in hepatocytes potentiates mitochondrial respiration and gluconeogenesis in a prohibitin-dependent way. J Biol Chem. 2019;294:12581-12598 pubmed publisher
Giraud S, Steichen C, Couturier P, Tillet S, Mallet V, Coudroy R, et al. Influence of Hypoxic Preservation Temperature on Endothelial Cells and Kidney Integrity. Biomed Res Int. 2019;2019:8572138 pubmed publisher
Booth A, Yue Z, Eykelenboom J, Stiff T, Luxton G, Hochegger H, et al. Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis. elife. 2019;8: pubmed publisher
Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, et al. DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B. Autophagy. 2019;:1-14 pubmed publisher
Georg I, Díaz Barreiro A, Morell M, Pey A, Alarcon Riquelme M. BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells. Cell Mol Immunol. 2019;: pubmed publisher
Sarkar C, Jones J, Hegdekar N, Thayer J, Kumar A, Faden A, et al. PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma. Autophagy. 2019;:1-20 pubmed publisher
Wilke G, Funkhouser Jones L, Wang Y, Ravindran S, Wang Q, Beatty W, et al. A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability. Cell Host Microbe. 2019;: pubmed publisher
Sengupta A, Holmes A. A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory. Neuron. 2019;: pubmed publisher
Gothe H, Bouwman B, Gusmao E, Piccinno R, Petrosino G, Sayols S, et al. Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations. Mol Cell. 2019;: pubmed publisher
Wu L, Xia M, Duan Y, Zhang L, Jiang H, Hu X, et al. Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans. Cell Death Dis. 2019;10:468 pubmed publisher
Wolfe K, Kofuji S, Yoshino H, Sasaki M, Okumura K, Sasaki A. Dynamic compartmentalization of purine nucleotide metabolic enzymes at leading edge in highly motile renal cell carcinoma. Biochem Biophys Res Commun. 2019;: pubmed publisher
Wang J, Liu J, Shao K, Han Y, Li G, Ming S, et al. PRRSV activates lipophagy to facilitate viral replication through down-regulation of NDRG1 expression. J Virol. 2019;: pubmed publisher
Shin Y, Moriya A, Tohnishi Y, Watanabe T, Imamura Y. Basement membrane-like structures containing NTH α1(IV) are formed around the endothelial cell network in a novel in vitro angiogenesis model. Am J Physiol Cell Physiol. 2019;317:C314-C325 pubmed publisher
Ahn J, Cho M, Sohn S, Lee J. Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape. Exp Mol Med. 2019;51:64 pubmed publisher
Caiazza C, D Agostino M, Passaro F, Faicchia D, Mallardo M, Paladino S, et al. Effects of Long-Term Citrate Treatment in the PC3 Prostate Cancer Cell Line. Int J Mol Sci. 2019;20: pubmed publisher
Zeitz M, Calhoun P, James C, Taetzsch T, George K, Robel S, et al. Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging. Cell Rep. 2019;27:2737-2747.e5 pubmed publisher
Ha S, Jeong S, Yi K, Chu J, Kim S, Kim E, et al. Autophagy Mediates Astrogenesis in Adult Hippocampal Neural Stem Cells. Exp Neurobiol. 2019;28:229-246 pubmed publisher
Niklaus L, Agop Nersesian C, Schmuckli Maurer J, Wacker R, Grünig V, Heussler V. Deciphering host lysosome-mediated elimination of Plasmodium berghei liver stage parasites. Sci Rep. 2019;9:7967 pubmed publisher
Civenni G, Bosotti R, Timpanaro A, Vazquez R, Merulla J, Pandit S, et al. Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer. Cell Metab. 2019;: pubmed publisher
Donadon I, Bussani E, Riccardi F, Licastro D, Romano G, Pianigiani G, et al. Rescue of spinal muscular atrophy mouse models with AAV9-Exon-specific U1 snRNA. Nucleic Acids Res. 2019;47:7618-7632 pubmed publisher
Persson E, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier J, et al. Protein crystallization promotes type 2 immunity and is reversible by antibody treatment. Science. 2019;364: pubmed publisher
Matthews B, Younger M, Vosshall L. The ion channel ppk301 controls freshwater egg-laying in the mosquito Aedes aegypti. elife. 2019;8: pubmed publisher
Rosas Salvans M, Scrofani J, Modol A, Vernos I. DnaJB6 is a RanGTP-regulated protein required for microtubule organization during mitosis. J Cell Sci. 2019;132: pubmed publisher
Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch K, Lillesaar C. Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. Biol Open. 2019;8: pubmed publisher
Sun Y, Ren Y, Yang F, He Y, Liang S, Guan L, et al. High-yield isolation of menstrual blood-derived endometrial stem cells by direct red blood cell lysis treatment. Biol Open. 2019;8: pubmed publisher
Kureel S, Mogha P, Khadpekar A, Kumar V, Joshi R, Das S, et al. Soft substrate maintains proliferative and adipogenic differentiation potential of human mesenchymal stem cells on long-term expansion by delaying senescence. Biol Open. 2019;8: pubmed publisher
Ritch S, Brandhagen B, Goyeneche A, Telleria C. Advanced assessment of migration and invasion of cancer cells in response to mifepristone therapy using double fluorescence cytochemical labeling. BMC Cancer. 2019;19:376 pubmed publisher
Ando T, Sekine S, Inagaki S, Misaki K, Badel L, Moriya H, et al. Nanopore Formation in the Cuticle of an Insect Olfactory Sensillum. Curr Biol. 2019;: pubmed publisher
Papanikos F, Clément J, Testa E, Ravindranathan R, Grey C, Dereli I, et al. Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes. Mol Cell. 2019;74:1069-1085.e11 pubmed publisher
Murru S, Hess S, Barth E, Almajan E, Schatton D, Hermans S, et al. Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. 2019;67:1526-1541 pubmed publisher
Wang Y, Brady K, Caiello B, Ackerson S, Stewart J. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association. Life Sci Alliance. 2019;2: pubmed publisher
Soltys J, Liu Y, Ritchie A, Wemlinger S, Schaller K, Schumann H, et al. Membrane assembly of aquaporin-4 autoantibodies regulates classical complement activation in neuromyelitis optica. J Clin Invest. 2019;129:2000-2013 pubmed publisher
Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher
Chakroborty D, Kurppa K, Paatero I, Ojala V, Koivu M, Tamirat M, et al. An unbiased in vitro screen for activating epidermal growth factor receptor mutations. J Biol Chem. 2019;294:9377-9389 pubmed publisher
Koster K, Francesconi W, Berton F, Alahmadi S, Srinivas R, Yoshii A. Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model. elife. 2019;8: pubmed publisher
Wiggins K, Parry A, Cassidy L, Humphry M, Webster S, Goodall J, et al. IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype. Aging Cell. 2019;18:e12946 pubmed publisher
Lacin H, Chen H, Long X, Singer R, Lee T, Truman J. Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS. elife. 2019;8: pubmed publisher
Gorla M, Santiago C, Chaudhari K, Layman A, Oliver P, Bashaw G. Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019;26:3298-3312.e4 pubmed publisher
Skjesol A, Yurchenko M, Bösl K, Gravastrand C, Nilsen K, Grøvdal L, et al. The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathog. 2019;15:e1007684 pubmed publisher
Ding Y, Lillvis J, Cande J, Berman G, Arthur B, Long X, et al. Neural Evolution of Context-Dependent Fly Song. Curr Biol. 2019;: pubmed publisher
Gong B, Kiyotani K, Sakata S, Nagano S, Kumehara S, Baba S, et al. Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer. J Exp Med. 2019;: pubmed publisher
Pujhari S, Brustolin M, Macias V, Nissly R, Nomura M, Kuchipudi S, et al. Heat shock protein 70 (Hsp70) mediates Zika virus entry, replication, and egress from host cells. Emerg Microbes Infect. 2019;8:8-16 pubmed publisher
Arceci A, Bonacci T, Wang X, Stewart K, Damrauer J, Hoadley K, et al. FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer. Cell Rep. 2019;26:3076-3086.e6 pubmed publisher
Riabinina O, Vernon S, Dickson B, Baines R. Split-QF System for Fine-Tuned Transgene Expression in Drosophila. Genetics. 2019;212:53-63 pubmed publisher
Jiang N, Rasmussen J, Clanton J, Rosenberg M, Luedke K, Cronan M, et al. A conserved morphogenetic mechanism for epidermal ensheathment of nociceptive sensory neurites. elife. 2019;8: pubmed publisher
Davidson L, Francis L, Cordiner R, Eaton J, Estell C, Macias S, et al. Rapid Depletion of DIS3, EXOSC10, or XRN2 Reveals the Immediate Impact of Exoribonucleolysis on Nuclear RNA Metabolism and Transcriptional Control. Cell Rep. 2019;26:2779-2791.e5 pubmed publisher
Vallardi G, Allan L, Crozier L, Saurin A. Division of labour between PP2A-B56 isoforms at the centromere and kinetochore. elife. 2019;8: pubmed publisher
Bowler M, Kong D, Sun S, Nanjundappa R, Evans L, Farmer V, et al. High-resolution characterization of centriole distal appendage morphology and dynamics by correlative STORM and electron microscopy. Nat Commun. 2019;10:993 pubmed publisher
Kamieniarz Gdula K, Gdula M, Panser K, Nojima T, Monks J, Wisniewski J, et al. Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination. Mol Cell. 2019;74:158-172.e9 pubmed publisher
Hsieh C, Yang W. Omegasome-proximal PtdIns(4,5)P2 couples F-actin mediated mitoaggregate disassembly with autophagosome formation during mitophagy. Nat Commun. 2019;10:969 pubmed publisher
Spies J, Lukas C, Somyajit K, Rask M, Lukas J, Neelsen K. 53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage. Nat Cell Biol. 2019;21:487-497 pubmed publisher
Keuss M, Hjerpe R, Hsia O, Gourlay R, Burchmore R, Trost M, et al. Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death. EMBO J. 2019;38: pubmed publisher
Gültekin Y, Steller H. Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila. Development. 2019;146: pubmed publisher
Bäck S, Necarsulmer J, Whitaker L, Coke L, Koivula P, Heathward E, et al. Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. Neuron. 2019;102:105-119.e8 pubmed publisher
Taneja N, Burnette D. Myosin IIA drives membrane bleb retraction. Mol Biol Cell. 2019;30:1051-1059 pubmed publisher
Pan X, Cao Y, Stucchi R, Hooikaas P, Portegies S, Will L, et al. MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon. Cell Rep. 2019;26:1988-1999.e6 pubmed publisher
Ogawa Y, Shiraki T, Asano Y, Muto A, Kawakami K, Suzuki Y, et al. Six6 and Six7 coordinately regulate expression of middle-wavelength opsins in zebrafish. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Korecki A, Hickmott J, Lam S, Dreolini L, Mathelier A, Baker O, et al. Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele. Genetics. 2019;211:1155-1177 pubmed publisher
Huntley M, Gao J, Termsarasab P, Wang L, Zeng S, Thammongkolchai T, et al. Association between TDP-43 and mitochondria in inclusion body myositis. Lab Invest. 2019;: pubmed publisher
Alpizar S, BAKER A, Gulledge A, Hoppa M. Loss of Neurofascin-186 Disrupts Alignment of AnkyrinG Relative to Its Binding Partners in the Axon Initial Segment. Front Cell Neurosci. 2019;13:1 pubmed publisher
Larson C, Sandoz K, Cockrell D, Heinzen R. Noncanonical Inhibition of mTORC1 by Coxiella burnetii Promotes Replication within a Phagolysosome-Like Vacuole. MBio. 2019;10: pubmed publisher
Liu R, Miller C, D Annibale C, Vo K, Jacobs A. Differential localizations of protein phosphatase 1 isoforms determine their physiological function in the heart. Acta Biochim Biophys Sin (Shanghai). 2019;51:323-330 pubmed publisher
Malaby H, Dumas M, Ohi R, Stumpff J. Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15. J Cell Biol. 2019;218:1218-1234 pubmed publisher
Ruiz K, Thaker T, Agnew C, Miller Vedam L, Trenker R, Herrera C, et al. Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. Nat Commun. 2019;10:531 pubmed publisher
Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, et al. PU.1 controls fibroblast polarization and tissue fibrosis. Nature. 2019;566:344-349 pubmed publisher
Addison W, Hall K, Kokabu S, Matsubara T, Fu M, Gori F, et al. Zfp423 Regulates Skeletal Muscle Regeneration and Proliferation. Mol Cell Biol. 2019;39: pubmed publisher
Nassour J, Radford R, Correia A, Fusté J, Schoell B, Jauch A, et al. Autophagic cell death restricts chromosomal instability during replicative crisis. Nature. 2019;565:659-663 pubmed publisher
Spence E, Dube S, Uezu A, Locke M, Soderblom E, Soderling S. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun. 2019;10:386 pubmed publisher
Zhou W, He Y, Rehman A, Kong Y, Hong S, Ding G, et al. Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus-CA3 projection. Nat Neurosci. 2019;22:205-217 pubmed publisher
Schilling T, Ali A, Leonhardt A, Borst A, Pujol Martí J. Transcriptional control of morphological properties of direction-selective T4/T5 neurons in Drosophila. Development. 2019;146: pubmed publisher
Hannaford M, Loyer N, Tonelli F, Zoltner M, Januschke J. A chemical-genetics approach to study the role of atypical Protein Kinase C in Drosophila. Development. 2019;146: pubmed publisher
Biggs R, Liu P, Stephens A, Marko J. Effects of altering histone post-translational modifications on mitotic chromosome structure and mechanics. Mol Biol Cell. 2019;:mbcE18090592 pubmed publisher
Mehto S, Jena K, Nath P, Chauhan S, Kolapalli S, Das S, et al. The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. Mol Cell. 2019;73:429-445.e7 pubmed publisher
Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand A, Robertson D, et al. RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019;73:413-428.e7 pubmed publisher
Kupferschmidt D, Augustin S, Johnson K, Lovinger D. Active Zone Proteins RIM1αβ Are Required for Normal Corticostriatal Transmission and Action Control. J Neurosci. 2019;39:1457-1470 pubmed publisher
Jones C, Hammer A, Cho Y, Sizemore G, Cukierman E, Yee L, et al. Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland. Neoplasia. 2019;21:132-145 pubmed publisher
Esquerre N, Basso L, Dubuquoy C, Djouina M, Chappard D, Blanpied C, et al. Aluminum Ingestion Promotes Colorectal Hypersensitivity in Rodents. Cell Mol Gastroenterol Hepatol. 2019;7:185-196 pubmed publisher
Huang T, Lin S, Malewicz N, Zhang Y, Zhang Y, Goulding M, et al. Identifying the pathways required for coping behaviours associated with sustained pain. Nature. 2019;565:86-90 pubmed publisher
Belfiore R, Rodin A, Ferreira E, Velázquez R, Branca C, Caccamo A, et al. Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice. Aging Cell. 2019;18:e12873 pubmed publisher
CHENG A, Yockteng Melgar J, Jarvis M, Malik Soni N, Borozan I, Carpenter M, et al. Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. Nat Microbiol. 2019;4:78-88 pubmed publisher
Motterlini R, Nikam A, Manin S, Ollivier A, Wilson J, Djouadi S, et al. HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide. Redox Biol. 2019;20:334-348 pubmed publisher
He Z, Gharaibeh R, Newsome R, Pope J, Dougherty M, Tomkovich S, et al. Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin. Gut. 2019;68:289-300 pubmed publisher
Werwein E, Cibis H, Hess D, Klempnauer K. Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization. Nucleic Acids Res. 2019;47:103-121 pubmed publisher
Sirko P, Gale J, Ashmore J. Intercellular Ca2+ signalling in the adult mouse cochlea. J Physiol. 2019;597:303-317 pubmed publisher
Guay C, Kruit J, Rome S, Menoud V, Mulder N, Jurdzinski A, et al. Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development. Cell Metab. 2019;29:348-361.e6 pubmed publisher
Chen M, Hsu W, Hsu S, Yang Y, Chuang T, Lin W, et al. PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency. Cell Death Differ. 2019;26:1221-1234 pubmed publisher
Stratikopoulos E, Kiess N, Szabolcs M, Pegno S, Kakit C, Wu X, et al. Mouse ER+/PIK3CAH1047R breast cancers caused by exogenous estrogen are heterogeneously dependent on estrogen and undergo BIM-dependent apoptosis with BH3 and PI3K agents. Oncogene. 2019;38:47-59 pubmed publisher
Bryant L, Lozynska O, Marsh A, Papp T, Van Gorder L, Serrano L, et al. Identification of a novel pathogenic missense mutation in PRPF31 using whole exome sequencing: a case report. Br J Ophthalmol. 2019;103:761-767 pubmed publisher
Verraes A, Cholley B, Galli T, Nola S. Comparative study of commercially available and homemade anti-VAMP7 antibodies using CRISPR/Cas9-depleted HeLa cells and VAMP7 knockout mice. F1000Res. 2018;7:1649 pubmed publisher
More J, Galusso N, Veloso P, Montecinos L, Finkelstein J, Sanchez G, et al. N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer's Disease Rat Model. Front Aging Neurosci. 2018;10:399 pubmed publisher
El Habta R, Sloniecka M, Kingham P, Backman L. The adipose tissue stromal vascular fraction secretome enhances the proliferation but inhibits the differentiation of myoblasts. Stem Cell Res Ther. 2018;9:352 pubmed publisher
Calise S, Abboud G, Kasahara H, Morel L, Chan E. Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments. Front Immunol. 2018;9:2789 pubmed publisher
Mereness J, Bhattacharya S, Wang Q, Ren Y, Pryhuber G, Mariani T. Type VI collagen promotes lung epithelial cell spreading and wound-closure. PLoS ONE. 2018;13:e0209095 pubmed publisher
Masola V, Bellin G, Vischini G, Dall Olmo L, Granata S, Gambaro G, et al. Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury. Oncotarget. 2018;9:36185-36201 pubmed publisher
Higo A, Kawashima T, Borg M, Zhao M, Lopez Vidriero I, Sakayama H, et al. Transcription factor DUO1 generated by neo-functionalization is associated with evolution of sperm differentiation in plants. Nat Commun. 2018;9:5283 pubmed publisher
Okamoto K, Ohishi T, Kuroiwa M, Iemura S, Natsume T, Seimiya H. MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs. Oncotarget. 2018;9:35844-35855 pubmed publisher
Ha H, Leal Ortiz S, Lalwani K, Kiyonaka S, Hamachi I, Mysore S, et al. Shank and Zinc Mediate an AMPA Receptor Subunit Switch in Developing Neurons. Front Mol Neurosci. 2018;11:405 pubmed publisher
Amrani N, Gao X, Liu P, Edraki A, Mir A, Ibraheim R, et al. NmeCas9 is an intrinsically high-fidelity genome-editing platform. Genome Biol. 2018;19:214 pubmed publisher
Šoltić D, Bowerman M, Stock J, Shorrock H, Gillingwater T, Fuller H. Multi-Study Proteomic and Bioinformatic Identification of Molecular Overlap between Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA). Brain Sci. 2018;8: pubmed publisher
Beldick S, Hong J, Altamentova S, Khazaei M, Hundal A, Zavvarian M, et al. Severe-combined immunodeficient rats can be used to generate a model of perinatal hypoxic-ischemic brain injury to facilitate studies of engrafted human neural stem cells. PLoS ONE. 2018;13:e0208105 pubmed publisher
Colina C, Puhl H, Ikeda S. Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons. Sci Rep. 2018;8:17379 pubmed publisher
Azorin P, Bonin F, Moukachar A, Ponceau A, Vacher S, Bieche I, et al. Distinct expression profiles and functions of Kindlins in breast cancer. J Exp Clin Cancer Res. 2018;37:281 pubmed publisher
Konjikusic M, Yeetong P, Boswell C, Lee C, Roberson E, Ittiwut R, et al. Mutations in Kinesin family member 6 reveal specific role in ependymal cell ciliogenesis and human neurological development. PLoS Genet. 2018;14:e1007817 pubmed publisher
Wang R, Deng X, Yuan C, Xin H, Liu G, Zhu Y, et al. IFT80 Improves Invasion Ability in Gastric Cancer Cell Line via ift80/p75NGFR/MMP9 Signaling. Int J Mol Sci. 2018;19: pubmed publisher
Domenech C, Maillard L, Rousseau A, Guidez F, Petit L, Pla M, et al. Studies in an Early Development Window Unveils a Severe HSC Defect in both Murine and Human Fanconi Anemia. Stem Cell Reports. 2018;11:1075-1091 pubmed publisher
Lee S, Abel E, Long F. Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018;9:4831 pubmed publisher
Ratnaparkhe M, Wong J, Wei P, Hlevnjak M, Kolb T, Simovic M, et al. Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors. Nat Commun. 2018;9:4760 pubmed publisher
Pill K, Melke J, Mühleder S, Pultar M, Rohringer S, Priglinger E, et al. Microvascular Networks From Endothelial Cells and Mesenchymal Stromal Cells From Adipose Tissue and Bone Marrow: A Comparison. Front Bioeng Biotechnol. 2018;6:156 pubmed publisher
Meseke M, Neumüller F, Brunne B, Li X, Anstötz M, Pohlkamp T, et al. Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin. Eneuro. 2018;5: pubmed publisher
Revinski D, Zaragosi L, Boutin C, Ruiz García S, Deprez M, Thomé V, et al. CDC20B is required for deuterosome-mediated centriole production in multiciliated cells. Nat Commun. 2018;9:4668 pubmed publisher
Moreno Vicente R, Pavón D, Martin Padura I, Català Montoro M, Díez Sánchez A, Quílez Álvarez A, et al. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep. 2018;25:1622-1635.e6 pubmed publisher
Rensing N, Moy B, Friedman J, Galindo R, Wong M. Longitudinal analysis of developmental changes in electroencephalography patterns and sleep-wake states of the neonatal mouse. PLoS ONE. 2018;13:e0207031 pubmed publisher
Deng Y, Pakdel M, Blank B, Sundberg E, Burd C, von Blume J. Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network. Dev Cell. 2018;47:464-478.e8 pubmed publisher
Soh H, Park S, Ryan K, Springer K, Maheshwari A, Tzingounis A. Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission. elife. 2018;7: pubmed publisher
Nguyen H, Labella S, Silva N, Jantsch V, Zetka M. C. elegans ZHP-4 is required at multiple distinct steps in the formation of crossovers and their transition to segregation competent chiasmata. PLoS Genet. 2018;14:e1007776 pubmed publisher
Thirunavukkarasu M, Selvaraju V, Joshi M, Coca Soliz V, Tapias L, Saad I, et al. Disruption of VEGF Mediated Flk-1 Signaling Leads to a Gradual Loss of Vessel Health and Cardiac Function During Myocardial Infarction: Potential Therapy With Pellino-1. J Am Heart Assoc. 2018;7:e007601 pubmed publisher
Osakada T, Ishii K, Mori H, Eguchi R, Ferrero D, Yoshihara Y, et al. Sexual rejection via a vomeronasal receptor-triggered limbic circuit. Nat Commun. 2018;9:4463 pubmed publisher
Bayo J, Tran T, Wang L, Peña Llopis S, Das A, Martinez E. Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks. Cell Rep. 2018;25:1040-1050.e5 pubmed publisher
Chen Y, Kozlov G, Fakih R, Funato Y, Miki H, Gehring K. The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg2+ efflux activity. J Biol Chem. 2018;293:19998-20007 pubmed publisher
Farhat K, Bodart G, Charlet Renard C, Desmet C, Moutschen M, Beguin Y, et al. Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae. Front Immunol. 2018;9:2175 pubmed publisher
Chandra S, Gray J, Kiosses W, Khurana A, Hitomi K, Crosby C, et al. Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nat Commun. 2018;9:4279 pubmed publisher
Gu A, Kho D, Johnson R, Graham E, O Carroll S. In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology. Biosensors (Basel). 2018;8: pubmed publisher
Yuan J, Ma Y, Huang T, Chen Y, Peng Y, Li B, et al. Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase. Mol Cell. 2018;72:380-394.e7 pubmed publisher
Beckers A, Ott T, Schuster Gossler K, Boldt K, Alten L, Ueffing M, et al. The evolutionary conserved FOXJ1 target gene Fam183b is essential for motile cilia in Xenopus but dispensable for ciliary function in mice. Sci Rep. 2018;8:14678 pubmed publisher
Eliason J, Afify A, Potter C, Matsumura L. A GAL80 Collection To Inhibit GAL4 Transgenes in Drosophila Olfactory Sensory Neurons. G3 (Bethesda). 2018;8:3661-3668 pubmed publisher
Wu Y, Lin C, Lin Y, Su W, Chiu W. Autophagy regulates vinorelbine sensitivity due to continued Keap1-mediated ROS generation in lung adenocarcinoma cells. Cell Death Discov. 2018;4:33 pubmed publisher
Hamanaka S, Umino A, Sato H, Hayama T, Yanagida A, Mizuno N, et al. Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation. Stem Cell Reports. 2018;11:988-997 pubmed publisher
Arai T, Tanaka M, Goda N. HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver. Sci Rep. 2018;8:14230 pubmed publisher
Stevenson M, Lensmire N, Swain R. Astrocytes and radial glia-like cells, but not neurons, display a nonapoptotic increase in caspase-3 expression following exercise. Brain Behav. 2018;8:e01110 pubmed publisher
Sun J, Larter N, Chahda J, Rioux D, Gumaste A, Carlson J. Humidity response depends on the small soluble protein Obp59a in Drosophila. elife. 2018;7: pubmed publisher
Basilicata M, Bruel A, Semplicio G, Valsecchi C, Aktas T, Duffourd Y, et al. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nat Genet. 2018;50:1442-1451 pubmed publisher
Wason M, Lu H, Yu L, Lahiri S, Mukherjee D, Shen C, et al. Cerium Oxide Nanoparticles Sensitize Pancreatic Cancer to Radiation Therapy through Oxidative Activation of the JNK Apoptotic Pathway. Cancers (Basel). 2018;10: pubmed publisher
Fetoni A, Zorzi V, Paciello F, Ziraldo G, Peres C, Raspa M, et al. Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway. Redox Biol. 2018;19:301-317 pubmed publisher
Yang H, Ralle M, Wolfgang M, Dhawan N, Burkhead J, Rodriguez S, et al. Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes. PLoS Biol. 2018;16:e2006519 pubmed publisher
Dunphy G, Flannery S, Almine J, Connolly D, Paulus C, Jønsson K, et al. Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage. Mol Cell. 2018;71:745-760.e5 pubmed publisher
Jia D, Augert A, Kim D, Eastwood E, Wu N, Ibrahim A, et al. Crebbp Loss Drives Small Cell Lung Cancer and Increases Sensitivity to HDAC Inhibition. Cancer Discov. 2018;8:1422-1437 pubmed publisher
Kim S, Lee Y, Tasaki T, Hwang J, Kang M, Yi E, et al. The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins. PLoS ONE. 2018;13:e0202260 pubmed publisher
Liu Q, Li S, Lu C, Yu C, Huang L. G protein γ subunit Gγ13 is essential for olfactory function and aggressive behavior in mice. Neuroreport. 2018;29:1333-1339 pubmed publisher
Han X, Li Y, Xu Y, Zhao X, Zhang Y, Yang X, et al. Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem. Nat Commun. 2018;9:3390 pubmed publisher
Smith B, Kiessling A, Lledo Garcia R, Dixon K, Catley M, Atherfold P, et al. Generation and characterization of a high affinity anti-human FcRn antibody, rozanolixizumab, and the effects of different molecular formats on the reduction of plasma IgG concentration. MAbs. 2018;: pubmed publisher
Preite S, Cannons J, Radtke A, Vujkovic Cvijin I, Gomez Rodriguez J, Volpi S, et al. Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity. Nat Immunol. 2018;19:986-1000 pubmed publisher
Kyogoku H, Wakayama T, Kitajima T, Miyano T. Single nucleolus precursor body formation in the pronucleus of mouse zygotes and SCNT embryos. PLoS ONE. 2018;13:e0202663 pubmed publisher
Tsafou K, Katschnig A, Radic Sarikas B, Mutz C, Iljin K, Schwentner R, et al. Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers. Oncotarget. 2018;9:31018-31031 pubmed publisher
Zhang Y, Liu S, Zhang Y, Goulding M, Wang Y, Ma Q. Timing Mechanisms Underlying Gate Control by Feedforward Inhibition. Neuron. 2018;99:941-955.e4 pubmed publisher
Unterer B, Wiesmann V, Gunasekaran M, Sticht H, Tenkerian C, Behrens J, et al. IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD. Biochem J. 2018;475:2955-2967 pubmed publisher
Peters M, Parker S, Grim J, Allard C, Levin J, Detrich H. Divergent Hemogen genes of teleosts and mammals share conserved roles in erythropoiesis: analysis using transgenic and mutant zebrafish. Biol Open. 2018;7: pubmed publisher
Bernard S, Myers M, Fang W, Zinda B, Smart C, Lambert D, et al. CXCL1 Derived from Mammary Fibroblasts Promotes Progression of Mammary Lesions to Invasive Carcinoma through CXCR2 Dependent Mechanisms. J Mammary Gland Biol Neoplasia. 2018;23:249-267 pubmed publisher
Nakazawa S, Mizuno H, Iwasato T. Differential dynamics of cortical neuron dendritic trees revealed by long-term in vivo imaging in neonates. Nat Commun. 2018;9:3106 pubmed publisher
Hollingsworth T, Radic M, Beranova Giorgianni S, Giorgianni F, Wang Y, Iannaccone A. Murine Retinal Citrullination Declines With Age and is Mainly Dependent on Peptidyl Arginine Deiminase 4 (PAD4). Invest Ophthalmol Vis Sci. 2018;59:3808-3815 pubmed publisher
Lebedeva E, Bagaev A, Pichugin A, Chulkina M, Lysenko A, Tutykhina I, et al. The differences in immunoadjuvant mechanisms of TLR3 and TLR4 agonists on the level of antigen-presenting cells during immunization with recombinant adenovirus vector. BMC Immunol. 2018;19:26 pubmed publisher
Riley J, Quarato G, Cloix C, Lopez J, O Prey J, Pearson M, et al. Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis. EMBO J. 2018;37: pubmed publisher
Kiang L, Ross B, Yao J, Shanmugam S, Andrews C, Hansen S, et al. Vitreous Cytokine Expression and a Murine Model Suggest a Key Role of Microglia in the Inflammatory Response to Retinal Detachment. Invest Ophthalmol Vis Sci. 2018;59:3767-3778 pubmed publisher
Majumder K, Wang J, Boftsi M, Fuller M, Rede J, Joshi T, et al. Parvovirus minute virus of mice interacts with sites of cellular DNA damage to establish and amplify its lytic infection. elife. 2018;7: pubmed publisher
Govorunova E, Sineshchekov O, Hemmati R, Janz R, Morelle O, Melkonian M, et al. Extending the Time Domain of Neuronal Silencing with Cryptophyte Anion Channelrhodopsins. Eneuro. 2018;5: pubmed publisher
Harding E, Yu X, Miao A, Andrews N, Ma Y, Ye Z, et al. A Neuronal Hub Binding Sleep Initiation and Body Cooling in Response to a Warm External Stimulus. Curr Biol. 2018;28:2263-2273.e4 pubmed publisher
Loureiro M, Zorzetto Fernandes A, Radoshitzky S, Chi X, Dallari S, Marooki N, et al. DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection. PLoS Pathog. 2018;14:e1007125 pubmed publisher
Muñoz Galdeano T, Reigada D, Del Águila A, Velez I, Caballero López M, Maza R, et al. Cell Specific Changes of Autophagy in a Mouse Model of Contusive Spinal Cord Injury. Front Cell Neurosci. 2018;12:164 pubmed publisher
Lund V, Madsen K, Kjaerulff O. Drosophila Rab2 controls endosome-lysosome fusion and LAMP delivery to late endosomes. Autophagy. 2018;14:1520-1542 pubmed publisher
Kelleher A, Milano Foster J, Behura S, Spencer T. Uterine glands coordinate on-time embryo implantation and impact endometrial decidualization for pregnancy success. Nat Commun. 2018;9:2435 pubmed publisher
Wang L, Cho Y, Tang Y, Wang J, Park J, Wu Y, et al. PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy. Cell Res. 2018;28:787-802 pubmed publisher
Ferrebee C, Li J, Haywood J, Pachura K, Robinson B, Hinrichs B, et al. Organic Solute Transporter α-β Protects Ileal Enterocytes From Bile Acid-Induced Injury. Cell Mol Gastroenterol Hepatol. 2018;5:499-522 pubmed publisher
Stanczyk P, Seidel M, White J, Viero C, George C, Zissimopoulos S, et al. Association of cardiac myosin-binding protein-C with the ryanodine receptor channel - putative retrograde regulation?. J Cell Sci. 2018;131: pubmed publisher
Zhang C, Gao J, Li M, Deng Y, Jiang C. p38? MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress. J Cell Sci. 2018;131: pubmed publisher
Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, et al. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. 2018;559:61-66 pubmed publisher
Jara O, Minogue P, Berthoud V, Beyer E. Chemical chaperone treatment improves levels and distributions of connexins in Cx50D47A mouse lenses. Exp Eye Res. 2018;175:192-198 pubmed publisher
Strunov A, Boldyreva L, Andreyeva E, Pavlova G, Popova J, Razuvaeva A, et al. Ultrastructural analysis of mitotic Drosophila S2 cells identifies distinctive microtubule and intracellular membrane behaviors. BMC Biol. 2018;16:68 pubmed publisher
Liang J, Fan J, Wang M, Niu Z, Zhang Z, Yuan L, et al. CDKN2A inhibits formation of homotypic cell-in-cell structures. Oncogenesis. 2018;7:50 pubmed publisher
Funabashi T, Katoh Y, Okazaki M, Sugawa M, Nakayama K. Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis. J Cell Biol. 2018;217:2867-2876 pubmed publisher
Velimezi G, Robinson Garcia L, Muñoz Martínez F, Wiegant W, Ferreira da Silva J, Owusu M, et al. Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48. Nat Commun. 2018;9:2280 pubmed publisher
Smith E, Angstadt S, Monteiro N, Zhang W, Khademhosseini A, Yelick P. Bioengineered Tooth Buds Exhibit Features of Natural Tooth Buds. J Dent Res. 2018;97:1144-1151 pubmed publisher
Shenoy P, Kuo A, Khan N, Gorham L, Nicholson J, Corradini L, et al. The Somatostatin Receptor-4 Agonist J-2156 Alleviates Mechanical Hypersensitivity in a Rat Model of Breast Cancer Induced Bone Pain. Front Pharmacol. 2018;9:495 pubmed publisher
Weinberger F, Nicol P, Starbatty J, Stubbendorff M, Becher P, Schrepfer S, et al. No effect of thymosin beta-4 on the expression of the transcription factor Islet-1 in the adult murine heart. Pharmacol Res Perspect. 2018;6:e00407 pubmed publisher
Hirono M, Watanabe S, Karube F, Fujiyama F, Kawahara S, Nagao S, et al. Perineuronal Nets in the Deep Cerebellar Nuclei Regulate GABAergic Transmission and Delay Eyeblink Conditioning. J Neurosci. 2018;38:6130-6144 pubmed publisher
Incontro S, Díaz Alonso J, Iafrati J, Vieira M, Asensio C, Sohal V, et al. The CaMKII/NMDA receptor complex controls hippocampal synaptic transmission by kinase-dependent and independent mechanisms. Nat Commun. 2018;9:2069 pubmed publisher
Baizabal J, Mistry M, Garcia M, Gómez N, Olukoya O, Tran D, et al. The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position. Neuron. 2018;98:945-962.e8 pubmed publisher
Hoffmann N, Weise S, Marinaro F, Vogel T, De Pietri Tonelli D. DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex. Front Neurosci. 2018;12:281 pubmed publisher
Bellelli R, Borel V, Logan C, Svendsen J, Cox D, Nye E, et al. Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Mol Cell. 2018;70:707-721.e7 pubmed publisher
Meng F, Li J, Yang X, Yuan X, Tang X. Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury. Int J Mol Med. 2018;42:851-860 pubmed publisher
Ribeiro de Almeida C, Dhir S, Dhir A, Moghaddam A, Sattentau Q, Meinhart A, et al. RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. Mol Cell. 2018;70:650-662.e8 pubmed publisher
Yu S, Li L, Tian W, Nie D, Mu W, Qiu F, et al. PEP06 polypeptide 30 exerts antitumour effect in colorectal carcinoma via inhibiting epithelial-mesenchymal transition. Br J Pharmacol. 2018;175:3111-3130 pubmed publisher
Lu F, Zhu J, Guo S, Wong B, Chehab F, Ferriero D, et al. Upregulation of cholesterol 24-hydroxylase following hypoxia-ischemia in neonatal mouse brain. Pediatr Res. 2018;83:1218-1227 pubmed publisher
Matsumoto N, Sekiya M, Tohyama K, Ishiyama Matsuura E, Sun Wada G, Wada Y, et al. Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment. Sci Rep. 2018;8:6701 pubmed publisher
Lee J, Miller J, Basu S, Kee T, Loo L. Building predictive in vitro pulmonary toxicity assays using high-throughput imaging and artificial intelligence. Arch Toxicol. 2018;92:2055-2075 pubmed publisher
Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed publisher
Takahashi C, Miyatake K, Kusakabe M, Nishida E. The atypical mitogen-activated protein kinase ERK3 is essential for establishment of epithelial architecture. J Biol Chem. 2018;293:8342-8361 pubmed publisher
Shosha E, Xu Z, Narayanan S, Lemtalsi T, Fouda A, Rojas M, et al. Mechanisms of Diabetes-Induced Endothelial Cell Senescence: Role of Arginase 1. Int J Mol Sci. 2018;19: pubmed publisher
Manian K, Bharathan S, Maddali M, Srivastava V, Srivastava A, Velayudhan S. Generation of an integration-free iPSC line (CSCRi005-A) from erythroid progenitor cells of a healthy Indian male individual. Stem Cell Res. 2018;29:148-151 pubmed publisher
Fang J, Yang J, Wu X, Zhang G, Li T, Wang X, et al. Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. Aging Cell. 2018;17:e12765 pubmed publisher
Cykowski M, Powell S, Appel J, Arumanayagam A, Rivera A, Appel S. Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis. Acta Neuropathol Commun. 2018;6:28 pubmed publisher
Pennington S, Klutho P, Xie L, Broadhurst K, Koval O, McCormick M, et al. Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription. Redox Biol. 2018;16:401-413 pubmed publisher
Kishimoto D, Kirino Y, Tamura M, Takeno M, Kunishita Y, Takase Minegishi K, et al. Dysregulated heme oxygenase-1low M2-like macrophages augment lupus nephritis via Bach1 induced by type I interferons. Arthritis Res Ther. 2018;20:64 pubmed publisher
Du S, McCall N, Park K, Guan Q, Fontina P, Ertel A, et al. Blockade of Tumor-Expressed PD-1 promotes lung cancer growth. Oncoimmunology. 2018;7:e1408747 pubmed publisher
Gong L, Liu F, Xiong Z, Qi R, Luo Z, Gong X, et al. Heterochromatin protects retinal pigment epithelium cells from oxidative damage by silencing p53 target genes. Proc Natl Acad Sci U S A. 2018;115:E3987-E3995 pubmed publisher
Tsunoda M, Miyamichi K, Eguchi R, Sakuma Y, Yoshihara Y, Kikusui T, et al. Identification of an Intra- and Inter-specific Tear Protein Signal in Rodents. Curr Biol. 2018;28:1213-1223.e6 pubmed publisher
Bazzani L, Donnini S, Giachetti A, Christofori G, Ziche M. PGE2 mediates EGFR internalization and nuclear translocation via caveolin endocytosis promoting its transcriptional activity and proliferation in human NSCLC cells. Oncotarget. 2018;9:14939-14958 pubmed publisher
Maruyama M, Hotta N, Nio Y, Hamagami K, Nagi T, Funata M, et al. Bombesin receptor subtype-3-expressing neurons regulate energy homeostasis through a novel neuronal pathway in the hypothalamus. Brain Behav. 2018;8:e00881 pubmed publisher
Guo X, Ma Z, Du B, Li T, Li W, Xu L, et al. Dop1 enhances conspecific olfactory attraction by inhibiting miR-9a maturation in locusts. Nat Commun. 2018;9:1193 pubmed publisher
Page T, Urbaniak A, Espirito Santo A, Danks L, Smallie T, Williams L, et al. Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-?B recruitment. Biochem Biophys Res Commun. 2018;499:260-266 pubmed publisher
Rayagiri S, Ranaldi D, Raven A, Mohamad Azhar N, Lefebvre O, Zammit P, et al. Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal. Nat Commun. 2018;9:1075 pubmed publisher
Chen H, Xing Y, Xia L, Chen Z, Yin S, Wang J. AAV-mediated NT-3 overexpression protects cochleae against noise-induced synaptopathy. Gene Ther. 2018;25:251-259 pubmed publisher
Shen A, Nieves Cintrón M, Deng Y, Shi Q, Chowdhury D, Qi J, et al. Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell. Nat Commun. 2018;9:1050 pubmed publisher
Wuttke T, Markopoulos F, Padmanabhan H, Wheeler A, Murthy V, Macklis J. Developmentally primed cortical neurons maintain fidelity of differentiation and establish appropriate functional connectivity after transplantation. Nat Neurosci. 2018;21:517-529 pubmed publisher
Ghézali G, Calvo C, Pillet L, Llense F, Ezan P, Pannasch U, et al. Connexin 30 controls astroglial polarization during postnatal brain development. Development. 2018;145: pubmed publisher
Kogut I, McCarthy S, Pavlova M, Astling D, Chen X, Jakimenko A, et al. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018;9:745 pubmed publisher
Akiyoshi S, Ishii T, Bai Z, Mombaerts P. Subpopulations of vomeronasal sensory neurons with coordinated coexpression of type 2 vomeronasal receptor genes are differentially dependent on Vmn2r1. Eur J Neurosci. 2018;47:887-900 pubmed publisher
Tsai K, Courtney D, Cullen B. Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. PLoS Pathog. 2018;14:e1006919 pubmed publisher
Gilbert A, Chevez Barrios P, Cykowski M. Perineurial-like Cells and EMA Expression in the Suprachoroidal Region of the Human Eye. J Histochem Cytochem. 2018;66:367-375 pubmed publisher
Carpier J, Zucchetti A, Bataille L, Dogniaux S, Shafaq Zadah M, Bardin S, et al. Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation. J Exp Med. 2018;215:1245-1265 pubmed publisher
Li R, Cauchy P, Ramamoorthy S, Boller S, Chavez L, Grosschedl R. Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming. Genes Dev. 2018;32:96-111 pubmed publisher
Xiong J, Kawagishi H, Yan Y, Liu J, Wells Q, Edmunds L, et al. A Metabolic Basis for Endothelial-to-Mesenchymal Transition. Mol Cell. 2018;69:689-698.e7 pubmed publisher
Gelegen C, Miracca G, Ran M, Harding E, Ye Z, Yu X, et al. Excitatory Pathways from the Lateral Habenula Enable Propofol-Induced Sedation. Curr Biol. 2018;28:580-587.e5 pubmed publisher
Puri S, Roy N, Russ H, Leonhardt L, French E, Roy R, et al. Replication confers β cell immaturity. Nat Commun. 2018;9:485 pubmed publisher
Tosic M, Allen A, Willmann D, Lepper C, Kim J, Duteil D, et al. Lsd1 regulates skeletal muscle regeneration and directs the fate of satellite cells. Nat Commun. 2018;9:366 pubmed publisher
Mishra J, More A, Kumar S. Elevated androgen levels induce hyperinsulinemia through increase in Ins1 transcription in pancreatic beta cells in female rats. Biol Reprod. 2018;98:520-531 pubmed publisher
Yatsenko A, Shcherbata H. Stereotypical architecture of the stem cell niche is spatiotemporally established by miR-125-dependent coordination of Notch and steroid signaling. Development. 2018;145: pubmed publisher
Dieguez H, Romeo H, González Fleitas M, Aranda M, Milne G, Rosenstein R, et al. Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice. Dis Model Mech. 2018;11: pubmed publisher
Stewart D, Marada S, Bodeen W, Truong A, Sakurada S, Pandit T, et al. Cleavage activates dispatched for Sonic Hedgehog ligand release. elife. 2018;7: pubmed publisher
Marchetti C, Zyner K, Ohnmacht S, Robson M, Haider S, Morton J, et al. Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule. J Med Chem. 2018;61:2500-2517 pubmed publisher
Espino Guarch M, Font Llitjós M, Murillo Cuesta S, Errasti Murugarren E, Celaya A, Girotto G, et al. Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss. elife. 2018;7: pubmed publisher
Yoshida S, Hagiwara Y, Tsuchiya M, Shinoda M, Koide M, Hatakeyama H, et al. Involvement of neutrophils and interleukin-18 in nociception in a mouse model of muscle pain. Mol Pain. 2018;14:1744806918757286 pubmed publisher
Panaliappan T, Wittmann W, Jidigam V, Mercurio S, Bertolini J, Sghari S, et al. Sox2 is required for olfactory pit formation and olfactory neurogenesis through BMP restriction and Hes5 upregulation. Development. 2018;145: pubmed publisher
Azasi Y, Lindergard G, Ghumra A, Mu J, Miller L, Rowe J. Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function. Proc Natl Acad Sci U S A. 2018;115:1063-1068 pubmed publisher
Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed publisher
Esmail S, Kartner N, Yao Y, Kim J, Reithmeier R, Manolson M. Molecular mechanisms of cutis laxa- and distal renal tubular acidosis-causing mutations in V-ATPase a subunits, ATP6V0A2 and ATP6V0A4. J Biol Chem. 2018;293:2787-2800 pubmed publisher
Mita P, Wudzinska A, Sun X, Andrade J, Nayak S, Kahler D, et al. LINE-1 protein localization and functional dynamics during the cell cycle. elife. 2018;7: pubmed publisher
Nüchel J, Ghatak S, Zuk A, Illerhaus A, Morgelin M, Schönborn K, et al. TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy. 2018;14:465-486 pubmed publisher
Smith M, Harley M, Kemp A, Wills J, Lee M, Arends M, et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 2018;44:217-232.e11 pubmed publisher
Wu D, Lee S, Luo J, Xia H, Gushchina S, Richardson P, et al. Intraneural Injection of ATP Stimulates Regeneration of Primary Sensory Axons in the Spinal Cord. J Neurosci. 2018;38:1351-1365 pubmed publisher
Hata K, Maeno Hikichi Y, Yumoto N, Burden S, Landmesser L. Distinct Roles of Different Presynaptic and Postsynaptic NCAM Isoforms in Early Motoneuron-Myotube Interactions Required for Functional Synapse Formation. J Neurosci. 2018;38:498-510 pubmed publisher
Liu W, Krump N, MacDonald M, You J. Merkel Cell Polyomavirus Infection of Animal Dermal Fibroblasts. J Virol. 2018;92: pubmed publisher
Payne E, Ramalingam D, Fox D, Klotman M. Polyploidy and Mitotic Cell Death Are Two Distinct HIV-1 Vpr-Driven Outcomes in Renal Tubule Epithelial Cells. J Virol. 2018;92: pubmed publisher
Murtuza M, Isokawa M. Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. J Neurochem. 2018;144:58-67 pubmed publisher
Terauchi A, Gavin E, Wilson J, Umemori H. Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis. Front Synaptic Neurosci. 2017;9:17 pubmed publisher
Zhang H, VOYTIK HARBIN S, Brookes S, Zhang L, Wallace J, Parker N, et al. Use of autologous adipose-derived mesenchymal stem cells for creation of laryngeal cartilage. Laryngoscope. 2017;: pubmed publisher
Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins. Cell. 2017;171:1692-1706.e18 pubmed publisher
Dufourt J, Bontonou G, Chartier A, Jahan C, Meunier A, Pierson S, et al. piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm. Nat Commun. 2017;8:1305 pubmed publisher
Stößel M, Rehra L, Haastert Talini K. Reflex-based grasping, skilled forelimb reaching, and electrodiagnostic evaluation for comprehensive analysis of functional recovery-The 7-mm rat median nerve gap repair model revisited. Brain Behav. 2017;7:e00813 pubmed publisher
Deng Z, Manz D, TORTI S, Torti F. Effects of ferroportin-mediated iron depletion in cells representative of different histological subtypes of prostate cancer. Antioxid Redox Signal. 2017;: pubmed publisher
Lehtimäki J, Fenix A, Kotila T, Balistreri G, Paavolainen L, Varjosalo M, et al. UNC-45a promotes myosin folding and stress fiber assembly. J Cell Biol. 2017;216:4053-4072 pubmed publisher
Xing J, Zhang A, Zhang H, Wang J, Li X, Zeng M, et al. TRIM29 promotes DNA virus infections by inhibiting innate immune response. Nat Commun. 2017;8:945 pubmed publisher
Farhy Tselnicker I, van Casteren A, Lee A, Chang V, Aricescu A, Allen N. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Neuron. 2017;96:428-445.e13 pubmed publisher
Li P, Fu X, Smith N, Ziobro J, Curiel J, Tenga M, et al. Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy. Neuron. 2017;96:387-401.e6 pubmed publisher
Zou J, Zhang B, Gutmann D, Wong M. Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age-dependent manner. Epilepsia. 2017;58:2053-2063 pubmed publisher
Dembitz V, Lalić H, Visnjic D. 5-Aminoimidazole-4-carboxamide ribonucleoside-induced autophagy flux during differentiation of monocytic leukemia cells. Cell Death Discov. 2017;3:17066 pubmed publisher
Kourtidis A, Necela B, Lin W, Lu R, Feathers R, Asmann Y, et al. Cadherin complexes recruit mRNAs and RISC to regulate epithelial cell signaling. J Cell Biol. 2017;216:3073-3085 pubmed publisher
Shao L, Saver M, Chung P, Ren Q, Lee T, Kent C, et al. Dissection of the Drosophila neuropeptide F circuit using a high-throughput two-choice assay. Proc Natl Acad Sci U S A. 2017;114:E8091-E8099 pubmed publisher
Chiang T, Wu H, Lee F. ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration. Mol Biol Cell. 2017;28:3013-3028 pubmed publisher
Kwun H, Wendzicki J, Shuda Y, Moore P, Chang Y. Merkel cell polyomavirus small T antigen induces genome instability by E3 ubiquitin ligase targeting. Oncogene. 2017;36:6784-6792 pubmed publisher
Yonekubo S, Tatemichi S, Maruyama K, Kobayashi M. Alpha1A-adrenoceptor antagonist improves underactive bladder associated with diabetic cystopathy via bladder blood flow in rats. BMC Urol. 2017;17:64 pubmed publisher
Dörpholz G, Murgai A, Jatzlau J, Horbelt D, Belverdi M, Heroven C, et al. IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation. Sci Rep. 2017;7:8778 pubmed publisher
Kanemaru H, Yamane F, Fukushima K, Matsuki T, Kawasaki T, Ebina I, et al. Antitumor effect of Batf2 through IL-12 p40 up-regulation in tumor-associated macrophages. Proc Natl Acad Sci U S A. 2017;114:E7331-E7340 pubmed publisher
Heilman P, Song S, Miranda C, Meyer K, Srivastava A, Knapp A, et al. HSPB1 mutations causing hereditary neuropathy in humans disrupt non-cell autonomous protection of motor neurons. Exp Neurol. 2017;297:101-109 pubmed publisher
Bohnenpoll T, Wittern A, Mamo T, Weiss A, Rudat C, Kleppa M, et al. A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017;13:e1006951 pubmed publisher
Lee M, Martinez Lozada Z, Krizman E, Robinson M. Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT-1 by a Notch-dependent mechanism. J Neurochem. 2017;143:489-506 pubmed publisher
Schedin Weiss S, Inoue M, Hromadkova L, Teranishi Y, Yamamoto N, Wiehager B, et al. Monoamine oxidase B is elevated in Alzheimer disease neurons, is associated with ?-secretase and regulates neuronal amyloid ?-peptide levels. Alzheimers Res Ther. 2017;9:57 pubmed publisher
Perroud J, Bernheim L, Frieden M, Koenig S. Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. J Cell Sci. 2017;130:3083-3093 pubmed publisher
Totland M, Bergsland C, Fykerud T, Knudsen L, Rasmussen N, Eide P, et al. The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions. J Cell Sci. 2017;130:2867-2882 pubmed publisher
Long K, Shipman K, Rbaibi Y, Menshikova E, Ritov V, Eshbach M, et al. Proximal tubule apical endocytosis is modulated by fluid shear stress via an mTOR-dependent pathway. Mol Biol Cell. 2017;28:2508-2517 pubmed publisher
Stenberg L, Stößel M, Ronchi G, Geuna S, Yin Y, Mommert S, et al. Regeneration of long-distance peripheral nerve defects after delayed reconstruction in healthy and diabetic rats is supported by immunomodulatory chitosan nerve guides. BMC Neurosci. 2017;18:53 pubmed publisher
Ishikawa Y, Okamoto N, Nakamura M, Kim H, Kamikouchi A. Anatomic and Physiologic Heterogeneity of Subgroup-A Auditory Sensory Neurons in Fruit Flies. Front Neural Circuits. 2017;11:46 pubmed publisher
Kan L, Grozhik A, Vedanayagam J, Patil D, Pang N, Lim K, et al. The m6A pathway facilitates sex determination in Drosophila. Nat Commun. 2017;8:15737 pubmed publisher
Mamo T, Wittern A, Kleppa M, Bohnenpoll T, Weiss A, Kispert A. BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017;26:3553-3563 pubmed publisher
Fang T, Kasbi K, Rothe S, Aziz W, Giese K. Age-dependent changes in autophosphorylation of alpha calcium/calmodulin dependent kinase II in hippocampus and amygdala after contextual fear conditioning. Brain Res Bull. 2017;134:18-23 pubmed publisher
Stefani C, González Rodríguez D, Senju Y, Doye A, Efimova N, Janel S, et al. Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation. Nat Commun. 2017;8:15839 pubmed publisher
Hindriksen S, Bramer A, Truong M, Vromans M, Post J, Verlaan Klink I, et al. Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells. PLoS ONE. 2017;12:e0179514 pubmed publisher
Takahashi H, Tsuboi H, Asashima H, Hirota T, Kondo Y, Moriyama M, et al. cDNA microarray analysis identifies NR4A2 as a novel molecule involved in the pathogenesis of Sjögren's syndrome. Clin Exp Immunol. 2017;190:96-109 pubmed publisher
Lange L, Marks M, Liu J, Wittler L, Bauer H, Piehl S, et al. Patterning and gastrulation defects caused by the tw18 lethal are due to loss of Ppp2r1a. Biol Open. 2017;6:752-764 pubmed publisher
Zane L, Chapus F, Pegoraro G, Misteli T. HiHiMap: single-cell quantitation of histones and histone posttranslational modifications across the cell cycle by high-throughput imaging. Mol Biol Cell. 2017;28:2290-2302 pubmed publisher
Tan S, Chadha S, Liu Y, Gabasova E, Perera D, Ahmed K, et al. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability. Cell. 2017;169:1105-1118.e15 pubmed publisher
Di Marco S, Hasanova Z, Kanagaraj R, Chappidi N, Altmannova V, Menon S, et al. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Mol Cell. 2017;66:658-671.e8 pubmed publisher
Gong F, Clouaire T, Aguirrebengoa M, Legube G, Miller K. Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair. J Cell Biol. 2017;216:1959-1974 pubmed publisher
DiGiuseppe S, Bienkowska Haba M, Guion L, Keiffer T, Sapp M. Human Papillomavirus Major Capsid Protein L1 Remains Associated with the Incoming Viral Genome throughout the Entry Process. J Virol. 2017;91: pubmed publisher
Young C, Eckert R, Adhikary G, Crumrine D, Elias P, Blumenberg M, et al. Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype. J Invest Dermatol. 2017;137:1868-1877 pubmed publisher
Ahadome S, Zhang C, Tannous E, Shen J, Zheng J. Small-molecule inhibition of Wnt signaling abrogates dexamethasone-induced phenotype of primary human trabecular meshwork cells. Exp Cell Res. 2017;357:116-123 pubmed publisher
Thul P, Ã…kesson L, Wiking M, Mahdessian D, Geladaki A, Ait Blal H, et al. A subcellular map of the human proteome. Science. 2017;356: pubmed publisher
Ugbode C, Smith I, Whalley B, Hirst W, Rattray M. Sonic hedgehog signalling mediates astrocyte crosstalk with neurons to confer neuroprotection. J Neurochem. 2017;142:429-443 pubmed publisher
Nieborowska Skorska M, Sullivan K, Dasgupta Y, Podszywalow Bartnicka P, Hoser G, Maifrede S, et al. Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells. J Clin Invest. 2017;127:2392-2406 pubmed publisher
Meng Z, Gong J, Chen Z, Sun J, Xiao Y, Wang L, et al. Glucose Sensing by Skeletal Myocytes Couples Nutrient Signaling to Systemic Homeostasis. Mol Cell. 2017;66:332-344.e4 pubmed publisher
Schludi M, Becker L, Garrett L, Gendron T, Zhou Q, Schreiber F, et al. Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss. Acta Neuropathol. 2017;134:241-254 pubmed publisher
Freeman L, Guo H, David C, Brickey W, JHA S, Ting J. NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes. J Exp Med. 2017;214:1351-1370 pubmed publisher
Corona B, Henderson B, Ward C, Greising S. Contribution of minced muscle graft progenitor cells to muscle fiber formation after volumetric muscle loss injury in wild-type and immune deficient mice. Physiol Rep. 2017;5: pubmed publisher
Morita M, Iwasaki R, Sato Y, Kobayashi T, Watanabe R, Oike T, et al. Elevation of pro-inflammatory cytokine levels following anti-resorptive drug treatment is required for osteonecrosis development in infectious osteomyelitis. Sci Rep. 2017;7:46322 pubmed publisher
Lagumersindez Denis N, Wrzos C, Mack M, Winkler A, van der Meer F, Reinert M, et al. Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis. Acta Neuropathol. 2017;134:15-34 pubmed publisher
Ross J, Webster R, Lechertier T, Reynolds L, Turmaine M, Bencze M, et al. Multiple roles of integrin-α3 at the neuromuscular junction. J Cell Sci. 2017;130:1772-1784 pubmed publisher
Vancevska A, Douglass K, Pfeiffer V, Manley S, Lingner J. The telomeric DNA damage response occurs in the absence of chromatin decompaction. Genes Dev. 2017;31:567-577 pubmed publisher
Calses P, Dhillon K, Tucker N, Chi Y, Huang J, Kawasumi M, et al. DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing. Cell Rep. 2017;19:162-174 pubmed publisher
Morita M, Takashima E, Ito D, Miura K, Thongkukiatkul A, Diouf A, et al. Immunoscreening of Plasmodium falciparum proteins expressed in a wheat germ cell-free system reveals a novel malaria vaccine candidate. Sci Rep. 2017;7:46086 pubmed publisher
Xiong G, Hindi S, Mann A, Gallot Y, Bohnert K, Cavener D, et al. The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration. elife. 2017;6: pubmed publisher
McFarland A, Luo S, Ahmed Qadri F, Zuck M, Thayer E, Goo Y, et al. Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State. Immunity. 2017;46:433-445 pubmed publisher
Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, et al. FMNL formins boost lamellipodial force generation. Nat Commun. 2017;8:14832 pubmed publisher
Hübner S, Sunny D, Pöhlke C, Ruhnau J, Vogelgesang A, Reich B, et al. Protective Effects of Fetal Zone Steroids Are Comparable to Estradiol in Hyperoxia-Induced Cell Death of Immature Glia. Endocrinology. 2017;158:1419-1435 pubmed publisher
Laporte M, Chatellard C, Vauchez V, Hemming F, Deloulme J, Vossier F, et al. Alix is required during development for normal growth of the mouse brain. Sci Rep. 2017;7:44767 pubmed publisher
Hubber A, Kubori T, Coban C, Matsuzawa T, Ogawa M, Kawabata T, et al. Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis. Sci Rep. 2017;7:44795 pubmed publisher
Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed publisher
Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed publisher
Jacquin E, Leclerc Mercier S, Judon C, Blanchard E, Fraitag S, Florey O. Pharmacological modulators of autophagy activate a parallel noncanonical pathway driving unconventional LC3 lipidation. Autophagy. 2017;13:854-867 pubmed publisher
Tatsumi K, Sakashita G, Nariai Y, Okazaki K, Kato H, Obayashi E, et al. G196 epitope tag system: a novel monoclonal antibody, G196, recognizes the small, soluble peptide DLVPR with high affinity. Sci Rep. 2017;7:43480 pubmed publisher
Miller A, Shah A, Aperi B, Kurpad S, Stemper B, Glavaski Joksimovic A. Acute death of astrocytes in blast-exposed rat organotypic hippocampal slice cultures. PLoS ONE. 2017;12:e0173167 pubmed publisher
Patel B, Fidalgo S, Wang C, Parmar L, Mandona K, Panossian A, et al. The TNF-α antagonist etanercept reverses age-related decreases in colonic SERT expression and faecal output in mice. Sci Rep. 2017;7:42754 pubmed publisher
Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, et al. Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis. Front Aging Neurosci. 2017;9:8 pubmed publisher
Almine J, O Hare C, Dunphy G, Haga I, Naik R, Atrih A, et al. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes. Nat Commun. 2017;8:14392 pubmed publisher
Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed publisher
Barca Mayo O, Pons Espinal M, Follert P, Armirotti A, Berdondini L, De Pietri Tonelli D. Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling. Nat Commun. 2017;8:14336 pubmed publisher
Katoh Y, Michisaka S, Nozaki S, Funabashi T, Hirano T, Takei R, et al. Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system. Mol Biol Cell. 2017;28:898-906 pubmed publisher
Zhang Y, Su S, Zhao S, Yang Z, Zhong C, Chen X, et al. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Nat Commun. 2017;8:14329 pubmed publisher
Biggins P, Brennan F, Taylor S, Woodruff T, Ruitenberg M. The Alternative Receptor for Complement Component 5a, C5aR2, Conveys Neuroprotection in Traumatic Spinal Cord Injury. J Neurotrauma. 2017;34:2075-2085 pubmed publisher
Wang L, Fu B, Li W, Patil G, Liu L, Dorf M, et al. Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction. Nat Commun. 2017;8:13876 pubmed publisher
Wang J, Lee J, Christian S, Dang Lawson M, Pritchard C, Freeman S, et al. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017;130:1094-1109 pubmed publisher
Zhu L, Almaca J, Dadi P, Hong H, Sakamoto W, Rossi M, et al. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nat Commun. 2017;8:14295 pubmed publisher
Servin Vences M, Moroni M, Lewin G, Poole K. Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes. elife. 2017;6: pubmed publisher
Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher
Tufail Y, Cook D, Fourgeaud L, Powers C, Merten K, Clark C, et al. Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia. Neuron. 2017;93:574-586.e8 pubmed publisher
Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, et al. Fibronectin-guided migration of carcinoma collectives. Nat Commun. 2017;8:14105 pubmed publisher
Yoo S, Latifkar A, Cerione R, Antonyak M. Cool-associated Tyrosine-phosphorylated Protein 1 Is Required for the Anchorage-independent Growth of Cervical Carcinoma Cells by Binding Paxillin and Promoting AKT Activation. J Biol Chem. 2017;292:3947-3957 pubmed publisher
Zhao D, Liang L, Wang S, Nakao T, Li Y, Liu L, et al. Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response. J Virol. 2017;91: pubmed publisher
Sheng N, Shi Y, Nicoll R. Amino-terminal domains of kainate receptors determine the differential dependence on Neto auxiliary subunits for trafficking. Proc Natl Acad Sci U S A. 2017;114:1159-1164 pubmed publisher
Wang Q, Fei P, Gu H, Zhang Y, Ke X, Liu Y. Different Phenotypes of the Two Chinese Probands with the Same c.889G>A (p.C162Y) Mutation in COCH Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromic Deafness 9. PLoS ONE. 2017;12:e0170011 pubmed publisher
Das D, Sengupta I, Sarkar N, Pal A, Saha D, Bandopadhyay M, et al. Anti-hepatitis B virus (HBV) response of imiquimod based toll like receptor 7 ligand in hbv-positive human hepatocelluar carcinoma cell line. BMC Infect Dis. 2017;17:76 pubmed publisher
Scott N, Rogers L, Prudova A, Brown N, Fortelny N, Overall C, et al. Interactome disassembly during apoptosis occurs independent of caspase cleavage. Mol Syst Biol. 2017;13:906 pubmed publisher
Eritja N, Chen B, Rodríguez Barrueco R, Santacana M, Gatius S, Vidal A, et al. Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer. Autophagy. 2017;13:608-624 pubmed publisher
Cai B, Wu J, Yu X, Su X, Wang R. FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions. MBio. 2017;8: pubmed publisher
Gerdøe Kristensen S, Lund V, Wandall H, Kjaerulff O. Mactosylceramide prevents glial cell overgrowth by inhibiting insulin and fibroblast growth factor receptor signaling. J Cell Physiol. 2017;232:3112-3127 pubmed publisher
Oh Y, Karube F, Takahashi S, Kobayashi K, Takada M, Uchigashima M, et al. Using a novel PV-Cre rat model to characterize pallidonigral cells and their terminations. Brain Struct Funct. 2017;222:2359-2378 pubmed publisher
Fry C, Johnson D, Ireland M, Noehren B. ACL injury reduces satellite cell abundance and promotes fibrogenic cell expansion within skeletal muscle. J Orthop Res. 2017;35:1876-1885 pubmed publisher
Hirano T, Katoh Y, Nakayama K. Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors. Mol Biol Cell. 2017;28:429-439 pubmed publisher
Ganesan M, Finsterwalder R, Leb H, Resch U, Neumüller K, de Martin R, et al. Three-Dimensional Coculture Model to Analyze the Cross Talk Between Endothelial and Smooth Muscle Cells. Tissue Eng Part C Methods. 2017;23:38-49 pubmed publisher
Yamamoto K, Sato K, Yukita M, Yasuda M, Omodaka K, Ryu M, et al. The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection. J Neurochem. 2017;140:495-508 pubmed publisher
Jusu S, Presley J, Kremer R. Phosphorylation of Human Retinoid X Receptor ? at Serine 260 Impairs Its Subcellular Localization, Receptor Interaction, Nuclear Mobility, and 1?,25-Dihydroxyvitamin D3-dependent DNA Binding in Ras-transformed Keratinocytes. J Biol Chem. 2017;292:1490-1509 pubmed publisher
Gao Y, Mruk D, Chen H, Lui W, Lee W, Cheng C. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin ?2 in the basement membrane. FASEB J. 2017;31:584-597 pubmed publisher
Zhu P, Liang L, Shao X, Luo W, Jiang S, Zhao Q, et al. Host Cellular Protein TRAPPC6AΔ Interacts with Influenza A Virus M2 Protein and Regulates Viral Propagation by Modulating M2 Trafficking. J Virol. 2017;91: pubmed publisher
Perez Sanchez J, Lorenzo L, Lecker I, Zurek A, Labrakakis C, Bridgwater E, et al. ?5GABAA Receptors Mediate Tonic Inhibition in the Spinal Cord Dorsal Horn and Contribute to the Resolution Of Hyperalgesia. J Neurosci Res. 2017;95:1307-1318 pubmed publisher
Goebbels S, Wieser G, Pieper A, Spitzer S, Weege B, Yan K, et al. A neuronal PI(3,4,5)P3-dependent program of oligodendrocyte precursor recruitment and myelination. Nat Neurosci. 2017;20:10-15 pubmed publisher
Biemans E, Jäkel L, de Waal R, Kuiperij H, Verbeek M. Limitations of the hCMEC/D3 cell line as a model for A? clearance by the human blood-brain barrier. J Neurosci Res. 2017;95:1513-1522 pubmed publisher
Li L, Chen J, Xiong G, St Clair D, Xu W, Xu R. Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. J Cell Sci. 2017;130:190-202 pubmed publisher
Barbier M, Houdayer C, Franchi G, Poncet F, Risold P. Melanin-concentrating hormone axons, but not orexin or tyrosine hydroxylase axons, innervate the claustrum in the rat: An immunohistochemical study. J Comp Neurol. 2017;525:1489-1498 pubmed publisher
Al Onaizi M, Parfitt G, Kolisnyk B, Law C, Guzman M, Barros D, et al. Regulation of Cognitive Processing by Hippocampal Cholinergic Tone. Cereb Cortex. 2017;27:1615-1628 pubmed publisher
Yeung H, Lo P, Ng D, Fong W. Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model. Cell Mol Immunol. 2017;14:223-234 pubmed publisher
Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar -, et al. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 2016;167:1264-1280.e18 pubmed publisher
Sohn J, Okamoto S, Kataoka N, Kaneko T, Nakamura K, Hioki H. Differential Inputs to the Perisomatic and Distal-Dendritic Compartments of VIP-Positive Neurons in Layer 2/3 of the Mouse Barrel Cortex. Front Neuroanat. 2016;10:124 pubmed publisher
Suzuki K, Yoshino D. Proliferation-Related Activity in Endothelial Cells Is Enhanced by Micropower Plasma. Biomed Res Int. 2016;2016:4651265 pubmed publisher
Lamprianou S, Gysemans C, Bou Saab J, Pontes H, Mathieu C, Meda P. Glibenclamide Prevents Diabetes in NOD Mice. PLoS ONE. 2016;11:e0168839 pubmed publisher
van de Ven R, de Groot J, Park D, van Domselaar R, de Jong D, Szuhai K, et al. p120-catenin prevents multinucleation through control of MKLP1-dependent RhoA activity during cytokinesis. Nat Commun. 2016;7:13874 pubmed publisher
Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed publisher
Kreger B, Johansen E, Cerione R, Antonyak M. The Enrichment of Survivin in Exosomes from Breast Cancer Cells Treated with Paclitaxel Promotes Cell Survival and Chemoresistance. Cancers (Basel). 2016;8: pubmed
Wang S, Jacquemyn J, Murru S, Martinelli P, Barth E, Langer T, et al. The Mitochondrial m-AAA Protease Prevents Demyelination and Hair Greying. PLoS Genet. 2016;12:e1006463 pubmed publisher
Dai S, Wang B, Li W, Wang L, Song X, Guo C, et al. Systemic application of 3-methyladenine markedly inhibited atherosclerotic lesion in ApoE-/- mice by modulating autophagy, foam cell formation and immune-negative molecules. Cell Death Dis. 2016;7:e2498 pubmed publisher
Paris N, Soroka A, Klose A, Liu W, Chakkalakal J. Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration. elife. 2016;5: pubmed publisher
de León Bautista M, Cárdenas Aguayo M, Casique Aguirre D, Almaraz Salinas M, Parraguirre Martínez S, Olivo Díaz A, et al. Immunological and Functional Characterization of RhoGDI3 and Its Molecular Targets RhoG and RhoB in Human Pancreatic Cancerous and Normal Cells. PLoS ONE. 2016;11:e0166370 pubmed publisher
Shatirishvili M, Burk A, Franz C, Pace G, Kastilan T, Breuhahn K, et al. Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress. Cell Death Dis. 2016;7:e2461 pubmed publisher
Capogrosso M, Milekovic T, Borton D, Wagner F, Moraud E, Mignardot J, et al. A brain-spine interface alleviating gait deficits after spinal cord injury in primates. Nature. 2016;539:284-288 pubmed publisher
Sinha R, Lee A, Rieke F, Haeseleer F. Lack of CaBP1/Caldendrin or CaBP2 Leads to Altered Ganglion Cell Responses. Eneuro. 2016;3: pubmed
Noordstra I, Liu Q, Nijenhuis W, Hua S, Jiang K, Baars M, et al. Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7. J Cell Sci. 2016;129:4278-4288 pubmed
Biswas U, Hempel K, Llano E, Pendas A, Jessberger R. Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis. PLoS Genet. 2016;12:e1006389 pubmed publisher
Kaneko Y, Pappas C, Tajiri N, Borlongan C. Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro. Sci Rep. 2016;6:35659 pubmed publisher
Kumar B, Dutta D, Iqbal J, Ansari M, Roy A, Chikoti L, et al. ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. PLoS Pathog. 2016;12:e1005960 pubmed publisher
Veglia E, Pini A, Moggio A, Grange C, Premoselli F, Miglio G, et al. Histamine type 1-receptor activation by low dose of histamine undermines human glomerular slit diaphragm integrity. Pharmacol Res. 2016;114:27-38 pubmed publisher
Chen N, Sugihara H, Kim J, Fu Z, Barak B, Sur M, et al. Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding. elife. 2016;5: pubmed publisher
Gómez Salinero J, López Olañeta M, Ortiz Sánchez P, Larrasa Alonso J, Gatto A, Felkin L, et al. The Calcineurin Variant CnA?1 Controls Mouse Embryonic Stem Cell Differentiation by Directing mTORC2 Membrane Localization and Activation. Cell Chem Biol. 2016;23:1372-1382 pubmed publisher
Wang J, Zhao S, Wei Y, Zhou Y, Shore P, Deng W. Cytoskeletal Filamin A Differentially Modulates RNA Polymerase III Gene Transcription in Transformed Cell Lines. J Biol Chem. 2016;291:25239-25246 pubmed
Ambite I, Puthia M, Nagy K, Cafaro C, Nadeem A, Butler D, et al. Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. PLoS Pathog. 2016;12:e1005848 pubmed publisher
Cvoro A, Bajić A, Zhang A, Simon M, Golic I, Sieglaff D, et al. Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PLoS ONE. 2016;11:e0164407 pubmed publisher
Rebman J, Kirchoff K, Walsh G. Cadherin-2 Is Required Cell Autonomously for Collective Migration of Facial Branchiomotor Neurons. PLoS ONE. 2016;11:e0164433 pubmed publisher
Parween S, Kostromina E, Nord C, Eriksson M, Lindstrom P, Ahlgren U. Intra-islet lesions and lobular variations in ?-cell mass expansion in ob/ob mice revealed by 3D imaging of intact pancreas. Sci Rep. 2016;6:34885 pubmed publisher
Kishi T, Mayanagi T, Iwabuchi S, Akasaka T, Sobue K. Myocardin-related transcription factor A (MRTF-A) activity-dependent cell adhesion is correlated to focal adhesion kinase (FAK) activity. Oncotarget. 2016;7:72113-72130 pubmed publisher
Khoutorsky A, Sorge R, Prager Khoutorsky M, Pawlowski S, Longo G, Jafarnejad S, et al. eIF2? phosphorylation controls thermal nociception. Proc Natl Acad Sci U S A. 2016;113:11949-11954 pubmed
Riabinina O, Task D, Marr E, Lin C, Alford R, O Brochta D, et al. Organization of olfactory centres in the malaria mosquito Anopheles gambiae. Nat Commun. 2016;7:13010 pubmed publisher
Murach K, Walton R, Fry C, Michaelis S, Groshong J, Finlin B, et al. Cycle training modulates satellite cell and transcriptional responses to a bout of resistance exercise. Physiol Rep. 2016;4: pubmed publisher
Casco Robles M, Islam M, Inami W, Tanaka H, Kunahong A, Yasumuro H, et al. Turning the fate of reprogramming cells from retinal disorder to regeneration by Pax6 in newts. Sci Rep. 2016;6:33761 pubmed publisher
Lin C, Potter C. Non-Mendelian Dominant Maternal Effects Caused by CRISPR/Cas9 Transgenic Components in Drosophila melanogaster. G3 (Bethesda). 2016;6:3685-3691 pubmed publisher
Valkenburg K, Amend S, Verdone J, van der Toom E, Hernandez J, Gorin M, et al. A simple selection-free method for detecting disseminated tumor cells (DTCs) in murine bone marrow. Oncotarget. 2016;7:69794-69803 pubmed publisher
Fykerud T, Knudsen L, Totland M, Sørensen V, Dahal Koirala S, Lothe R, et al. Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding. Cell Cycle. 2016;15:2943-2957 pubmed
Xie X, Tsai S, Tsai M. COUP-TFII regulates satellite cell function and muscular dystrophy. J Clin Invest. 2016;126:3929-3941 pubmed publisher
Yazdani A, Khoja Z, Johnstone A, Dale L, Rampakakis E, Wintermark P. Sildenafil Improves Brain Injury Recovery following Term Neonatal Hypoxia-Ischemia in Male Rat Pups. Dev Neurosci. 2016;38:251-263 pubmed
Clairfeuille T, Mas C, Chan A, Yang Z, Tello Lafoz M, Chandra M, et al. A molecular code for endosomal recycling of phosphorylated cargos by the SNX27-retromer complex. Nat Struct Mol Biol. 2016;23:921-932 pubmed publisher
Cunningham C, Li S, Vizeacoumar F, Bhanumathy K, Lee J, Parameswaran S, et al. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. 2016;7:61544-61561 pubmed publisher
Kalbe B, Schlimm M, Mohrhardt J, Scholz P, Jansen F, Hatt H, et al. Helional induces Ca2+ decrease and serotonin secretion of QGP-1 cells via a PKG-mediated pathway. J Mol Endocrinol. 2016;57:201-10 pubmed publisher
Inoue T, Griffin D, Huq R, Samuel E, Ruano S, Stinnett G, et al. Characterization of a novel MR-detectable nanoantioxidant that mitigates the recall immune response. NMR Biomed. 2016;29:1436-44 pubmed publisher
Piotrowski Daspit A, Nelson C. Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix. J Vis Exp. 2016;: pubmed publisher
Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, et al. Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice. J Mol Cell Cardiol. 2016;99:35-46 pubmed publisher
Hauck L, Grothe D, Billia F. p21(CIP1/WAF1)-dependent inhibition of cardiac hypertrophy in response to Angiotensin II involves Akt/Myc and pRb signaling. Peptides. 2016;83:38-48 pubmed publisher
López Montero N, Ramos Marquès E, Risco C, Garcia del Portillo F. Intracellular Salmonella induces aggrephagy of host endomembranes in persistent infections. Autophagy. 2016;12:1886-1901 pubmed
Zhang L, Ren F, Zhang X, Wang X, Shi H, Zhou L, et al. Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure. Dis Model Mech. 2016;9:799-809 pubmed publisher
Choi M, Ahn S, Yang E, Kim H, Chong Y, Kim H. Hippocampus-based contextual memory alters the morphological characteristics of astrocytes in the dentate gyrus. Mol Brain. 2016;9:72 pubmed publisher
Augustin V, Bold C, Wadle S, Langer J, Jabs R, Philippot C, et al. Functional anisotropic panglial networks in the lateral superior olive. Glia. 2016;64:1892-911 pubmed publisher
Foote C, Castorena Gonzalez J, Ramirez Perez F, Jia G, Hill M, Reyes Aldasoro C, et al. Arterial Stiffening in Western Diet-Fed Mice Is Associated with Increased Vascular Elastin, Transforming Growth Factor-?, and Plasma Neuraminidase. Front Physiol. 2016;7:285 pubmed publisher
Ortega de San Luis C, Pascual A. Simultaneous Detection of Both GDNF and GFR?1 Expression Patterns in the Mouse Central Nervous System. Front Neuroanat. 2016;10:73 pubmed publisher
Saisana M, Griffin S, May F. Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. Oncotarget. 2016;7:54445-54462 pubmed publisher
Kojima Y, Volkmer J, McKenna K, Civelek M, Lusis A, Miller C, et al. CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature. 2016;536:86-90 pubmed
Gallagher C, Walter P. Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. elife. 2016;5: pubmed publisher
Taneja N, Fenix A, Rathbun L, Millis B, Tyska M, Hehnly H, et al. Focal adhesions control cleavage furrow shape and spindle tilt during mitosis. Sci Rep. 2016;6:29846 pubmed publisher
Skytt D, Toft Kehler A, Brændstrup C, Cejvanovic S, Gurubaran I, Bergersen L, et al. Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Müller Cells and Retinal Ganglion Cells. Biomed Res Int. 2016;2016:1087647 pubmed publisher
Yang Y, Wang Z, Jin S, Gao D, Liu N, Chen S, et al. Opposite monosynaptic scaling of BLP-vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory. Nat Commun. 2016;7:11935 pubmed publisher
Avril M, Bernabeu M, Benjamin M, Brazier A, Smith J. Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells. MBio. 2016;7: pubmed publisher
Yagi R, Mabuchi Y, Mizunami M, Tanaka N. Convergence of multimodal sensory pathways to the mushroom body calyx in Drosophila melanogaster. Sci Rep. 2016;6:29481 pubmed publisher
Hewitt G, Carroll B, Sarallah R, Correia Melo C, Ogrodnik M, Nelson G, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 2016;12:1917-1930 pubmed
Pan H, Zhong X, Lee S. Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis. BMC Biochem. 2016;17:14 pubmed publisher
Fernández B, Fdez E, Gomez Suaga P, Gil F, Molina Villalba I, Ferrer I, et al. Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A. Autophagy. 2016;12:1487-506 pubmed publisher
Mona B, Avila J, Meredith D, Kollipara R, Johnson J. Regulating the dorsal neural tube expression of Ptf1a through a distal 3' enhancer. Dev Biol. 2016;418:216-225 pubmed publisher
van Veen J, Pringle D, McMahon M. P2A-Fluorophore Tagging of BRAF Tightly Links Expression to Fluorescence In Vivo. PLoS ONE. 2016;11:e0157661 pubmed publisher
Heman Ackah S, Bassett A, Wood M. Precision Modulation of Neurodegenerative Disease-Related Gene Expression in Human iPSC-Derived Neurons. Sci Rep. 2016;6:28420 pubmed publisher
Janeček M, Rossmann M, Sharma P, Emery A, Huggins D, Stockwell S, et al. Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2. Sci Rep. 2016;6:28528 pubmed publisher
Myers E, Yuan L, Felmlee M, Lin Y, Jiang Y, Pei Y, et al. A novel mutant Na+ /HCO3- cotransporter NBCe1 in a case of compound-heterozygous inheritance of proximal renal tubular acidosis. J Physiol. 2016;594:6267-6286 pubmed publisher
Lin C, Potter C. Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster. Genetics. 2016;203:1613-28 pubmed publisher
Ueno K, Takeuchi Y, Samura M, Tanaka Y, Nakamura T, Nishimoto A, et al. Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts. Sci Rep. 2016;6:28538 pubmed publisher
Meng X, Wang W, Lu H, He L, Chen W, Chao E, et al. Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders. elife. 2016;5: pubmed publisher
Ure K, Lu H, Wang W, Ito Ishida A, Wu Z, He L, et al. Restoration of Mecp2 expression in GABAergic neurons is sufficient to rescue multiple disease features in a mouse model of Rett syndrome. elife. 2016;5: pubmed publisher
Eymery A, Liu Z, Ozonov E, Stadler M, Peters A. The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos. Development. 2016;143:2767-79 pubmed publisher
Toneff M, Sreekumar A, Tinnirello A, Hollander P, Habib S, Li S, et al. The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states. BMC Biol. 2016;14:47 pubmed publisher
Stefaniuk M, Gualda E, Pawlowska M, Legutko D, Matryba P, Koza P, et al. Light-sheet microscopy imaging of a whole cleared rat brain with Thy1-GFP transgene. Sci Rep. 2016;6:28209 pubmed publisher
Farup J, Dalgas U, Keytsman C, Eijnde B, Wens I. High Intensity Training May Reverse the Fiber Type Specific Decline in Myogenic Stem Cells in Multiple Sclerosis Patients. Front Physiol. 2016;7:193 pubmed publisher
Gomez Diaz C, Bargeton B, Abuin L, Bukar N, Reina J, Bartoi T, et al. A CD36 ectodomain mediates insect pheromone detection via a putative tunnelling mechanism. Nat Commun. 2016;7:11866 pubmed publisher
Safaiyan S, Kannaiyan N, Snaidero N, Brioschi S, Biber K, Yona S, et al. Age-related myelin degradation burdens the clearance function of microglia during aging. Nat Neurosci. 2016;19:995-8 pubmed publisher
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
Sharma N, Kumawat K, Rastogi M, Basu A, Singh S. Japanese Encephalitis Virus exploits the microRNA-432 to regulate the expression of Suppressor of Cytokine Signaling (SOCS) 5. Sci Rep. 2016;6:27685 pubmed publisher
Geng F, Cheng X, Wu X, Yoo J, Cheng C, Guo J, et al. Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clin Cancer Res. 2016;22:5337-5348 pubmed
Prabhudesai S, Bensabeur F, Abdullah R, Basak I, Baez S, Alves G, et al. LRRK2 knockdown in zebrafish causes developmental defects, neuronal loss, and synuclein aggregation. J Neurosci Res. 2016;94:717-35 pubmed publisher
Penterling C, Drexler G, Böhland C, Stamp R, Wilke C, Braselmann H, et al. Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair. PLoS ONE. 2016;11:e0156599 pubmed publisher
Byrum M, Pondenis H, Fredrickson R, Wycislo K, Fan T. Downregulation of CXCR4 Expression and Functionality After Zoledronate Exposure in Canine Osteosarcoma. J Vet Intern Med. 2016;30:1187-96 pubmed publisher
Mathan J, Ismail S, McGhee J, McGhee C, Sherwin T. Sphere-forming cells from peripheral cornea demonstrate the ability to repopulate the ocular surface. Stem Cell Res Ther. 2016;7:81 pubmed publisher
Raman R, Damle I, Rote R, Banerjee S, Dingare C, Sonawane M. aPKC regulates apical localization of Lgl to restrict elongation of microridges in developing zebrafish epidermis. Nat Commun. 2016;7:11643 pubmed publisher
Uhlirova H, Kılıç K, Tian P, Thunemann M, Desjardins M, Saisan P, et al. Cell type specificity of neurovascular coupling in cerebral cortex. elife. 2016;5: pubmed publisher
Hilbers F, Luijsterburg M, Wiegant W, Meijers C, Völker Albert M, Boonen R, et al. Functional Analysis of Missense Variants in the Putative Breast Cancer Susceptibility Gene XRCC2. Hum Mutat. 2016;37:914-25 pubmed publisher
Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, et al. Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. Am J Physiol Gastrointest Liver Physiol. 2016;311:G396-411 pubmed publisher
Steed E, Faggianelli N, Roth S, Ramspacher C, Concordet J, Vermot J. klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nat Commun. 2016;7:11646 pubmed publisher
Di Pietro N, Giardinelli A, Sirolli V, Riganti C, Di Tomo P, Gazzano E, et al. Nitric oxide synthetic pathway and cGMP levels are altered in red blood cells from end-stage renal disease patients. Mol Cell Biochem. 2016;417:155-67 pubmed publisher
He F, Wei L, Luo W, Liao Z, Li B, Zhou X, et al. Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS. Oncotarget. 2016;7:37000-37012 pubmed publisher
Turner K, Hawkins T, Yáñez J, Anadón R, Wilson S, Folgueira M. Afferent Connectivity of the Zebrafish Habenulae. Front Neural Circuits. 2016;10:30 pubmed publisher
Komatsu Y, Ibi M, Chosa N, Kyakumoto S, Kamo M, Shibata T, et al. Zoledronic acid suppresses transforming growth factor-?-induced fibrogenesis by human gingival fibroblasts. Int J Mol Med. 2016;38:139-47 pubmed publisher
Humoud M, Doyle N, Royall E, Willcocks M, Sorgeloos F, van Kuppeveld F, et al. Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage. J Virol. 2016;90:6489-6501 pubmed publisher
Di Lascio S, Belperio D, Benfante R, Fornasari D. Alanine Expansions Associated with Congenital Central Hypoventilation Syndrome Impair PHOX2B Homeodomain-mediated Dimerization and Nuclear Import. J Biol Chem. 2016;291:13375-93 pubmed publisher
Fullenkamp C, Hall S, Jaber O, Pakalniskis B, Savage E, Savage J, et al. TAZ and YAP are frequently activated oncoproteins in sarcomas. Oncotarget. 2016;7:30094-108 pubmed publisher
Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, et al. IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections. Sci Transl Med. 2016;8:336ra59 pubmed publisher
Jeanson L, Thomas L, Copin B, Coste A, Sermet Gaudelus I, Dastot Le Moal F, et al. Mutations in GAS8, a Gene Encoding a Nexin-Dynein Regulatory Complex Subunit, Cause Primary Ciliary Dyskinesia with Axonemal Disorganization. Hum Mutat. 2016;37:776-85 pubmed publisher
Pionnier N, Brotin E, Karadjian G, Hemon P, Gaudin Nomé F, Vallarino Lhermitte N, et al. Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae. PLoS Negl Trop Dis. 2016;10:e0004605 pubmed publisher
Balcova M, Faltusova B, Gergelits V, Bhattacharyya T, Mihola O, Trachtulec Z, et al. Hybrid Sterility Locus on Chromosome X Controls Meiotic Recombination Rate in Mouse. PLoS Genet. 2016;12:e1005906 pubmed publisher
Cortés C, McInerney Leo A, Vogel I, Rondón Galeano M, Leo P, Harris J, et al. Mutations in human C2CD3 cause skeletal dysplasia and provide new insights into phenotypic and cellular consequences of altered C2CD3 function. Sci Rep. 2016;6:24083 pubmed publisher
Ono W, Sakagami N, Nishimori S, Ono N, Kronenberg H. Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation. Nat Commun. 2016;7:11277 pubmed publisher
Ufimtseva E. Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro. J Immunol Res. 2016;2016:4325646 pubmed publisher
Bubenheimer R, Brown I, Fried D, McClain J, Gulbransen B. Sirtuin-3 Is Expressed by Enteric Neurons but It Does not Play a Major Role in Their Regulation of Oxidative Stress. Front Cell Neurosci. 2016;10:73 pubmed publisher
Jo S, Lee Y, Kim S, Lee H, Chung H. PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells. Biochim Biophys Acta. 2016;1863:1499-509 pubmed publisher
Polanco J, Scicluna B, Hill A, Götz J. Extracellular Vesicles Isolated from the Brains of rTg4510 Mice Seed Tau Protein Aggregation in a Threshold-dependent Manner. J Biol Chem. 2016;291:12445-66 pubmed publisher
Bodenstine T, Chandler G, Reed D, Margaryan N, Gilgur A, Atkinson J, et al. Nodal expression in triple-negative breast cancer: Cellular effects of its inhibition following doxorubicin treatment. Cell Cycle. 2016;15:1295-302 pubmed publisher
Mutschelknaus L, Peters C, Winkler K, Yentrapalli R, Heider T, Atkinson M, et al. Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation. PLoS ONE. 2016;11:e0152213 pubmed publisher
Destouches D, Sader M, Terry S, Marchand C, Maillé P, Soyeux P, et al. Implication of NPM1 phosphorylation and preclinical evaluation of the nucleoprotein antagonist N6L in prostate cancer. Oncotarget. 2016;7:69397-69411 pubmed publisher
Katoh Y, Terada M, Nishijima Y, Takei R, Nozaki S, Hamada H, et al. Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex. J Biol Chem. 2016;291:10962-75 pubmed publisher
Cheng Y, Chikwava K, Wu C, Zhang H, Bhagat A, Pei D, et al. LNK/SH2B3 regulates IL-7 receptor signaling in normal and malignant B-progenitors. J Clin Invest. 2016;126:1267-81 pubmed publisher
Liao H, Ren X, Peterson B, Marshak D, Yau K, Gamlin P, et al. Melanopsin-expressing ganglion cells on macaque and human retinas form two morphologically distinct populations. J Comp Neurol. 2016;524:2845-72 pubmed publisher
Gu Y, Li G, Chen Y, Huang L. Epac-protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation. Pain. 2016;157:1541-50 pubmed publisher
Stempel H, Jung M, Pérez Gómez A, Leinders Zufall T, Zufall F, Bufe B. Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems. J Biol Chem. 2016;291:9762-75 pubmed publisher
Thibaudin M, Chaix M, Boidot R, Végran F, Derangère V, Limagne E, et al. Human ectonucleotidase-expressing CD25high Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions. Oncoimmunology. 2016;5:e1055444 pubmed
Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed publisher
Saygideğer Kont Y, Minas T, Jones H, Hour S, Çelik H, Temel I, et al. Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non-Small Cell Lung Cancer Cells. Neoplasia. 2016;18:111-20 pubmed publisher
Matsumoto M, Nakamachi T, Watanabe J, Sugiyama K, Ohtaki H, Murai N, et al. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke. J Mol Neurosci. 2016;59:270-9 pubmed publisher
Sheng L, Ruan C, Ma Y, Chen D, Kong L, Zhu D, et al. Beta3 adrenergic receptor is involved in vascular injury in deoxycorticosterone acetate-salt hypertensive mice. FEBS Lett. 2016;590:769-78 pubmed publisher
Laird A, Mackovski N, Rinkwitz S, Becker T, Giacomotto J. Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages. Hum Mol Genet. 2016;25:1728-38 pubmed publisher
McNally A, Poplawski S, Mayweather B, White K, Abel T. Characterization of a Novel Chromatin Sorting Tool Reveals Importance of Histone Variant H3.3 in Contextual Fear Memory and Motor Learning. Front Mol Neurosci. 2016;9:11 pubmed publisher
Juárez Morales J, Schulte C, Pezoa S, Vallejo G, Hilinski W, England S, et al. Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Dev. 2016;11:5 pubmed publisher
Liang W, Li X, Gao B, Gan H, Lin X, Liao L, et al. Observing the development of the temporomandibular joint in embryonic and post-natal mice using various staining methods. Exp Ther Med. 2016;11:481-489 pubmed
Fushiki A, Zwart M, Kohsaka H, Fetter R, Cardona A, Nose A. A circuit mechanism for the propagation of waves of muscle contraction in Drosophila. elife. 2016;5: pubmed publisher
Wike C, Graves H, Hawkins R, Gibson M, Ferdinand M, Zhang T, et al. Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis. elife. 2016;5:e11402 pubmed publisher
Schneider R, Schenone M, Ferreira M, Kramann R, Joyce C, Hartigan C, et al. Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9. Nat Med. 2016;22:288-97 pubmed publisher
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, et al. ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun. 2016;7:10498 pubmed publisher
Bachstetter A, Zhou Z, Rowe R, Xing B, Goulding D, Conley A, et al. MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses. PLoS ONE. 2016;11:e0149451 pubmed publisher
Grocott T, Thomas P, Münsterberg A. Atlas Toolkit: Fast registration of 3D morphological datasets in the absence of landmarks. Sci Rep. 2016;6:20732 pubmed publisher
Johnson D, Hooker E, Luong R, Yu E, He Y, Gonzalgo M, et al. Conditional Expression of the Androgen Receptor Increases Susceptibility of Bladder Cancer in Mice. PLoS ONE. 2016;11:e0148851 pubmed publisher
Furuyama W, Marzi A, Nanbo A, Haddock E, Maruyama J, Miyamoto H, et al. Discovery of an antibody for pan-ebolavirus therapy. Sci Rep. 2016;6:20514 pubmed publisher
Dupouy D, Ciftlik A, Fiche M, Heintze D, Bisig B, de Leval L, et al. Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer. Sci Rep. 2016;6:20277 pubmed publisher
Hernández Ochoa E, Vanegas C, Iyer S, Lovering R, Schneider M. Alternating bipolar field stimulation identifies muscle fibers with defective excitability but maintained local Ca(2+) signals and contraction. Skelet Muscle. 2016;6:6 pubmed publisher
Menon R, Behnia F, Polettini J, Saade G, Campisi J, Velarde M. Placental membrane aging and HMGB1 signaling associated with human parturition. Aging (Albany NY). 2016;8:216-30 pubmed
Hsu C, Bhandawat V. Organization of descending neurons in Drosophila melanogaster. Sci Rep. 2016;6:20259 pubmed publisher
Lazarevic I, Engelhardt B. Modeling immune functions of the mouse blood-cerebrospinal fluid barrier in vitro: primary rather than immortalized mouse choroid plexus epithelial cells are suited to study immune cell migration across this brain barrier. Fluids Barriers CNS. 2016;13:2 pubmed publisher
Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher
De Stasi A, Farisello P, Marcon I, Cavallari S, Forli A, Vecchia D, et al. Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy. Cereb Cortex. 2016;26:1778-94 pubmed publisher
Toyama E, Herzig S, Courchet J, Lewis T, Losón O, Hellberg K, et al. Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress. Science. 2016;351:275-281 pubmed publisher
Arentson Lantz E, English K, Paddon Jones D, Fry C. Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults. J Appl Physiol (1985). 2016;120:965-75 pubmed publisher
Najafi E, Stoodley M, Bilston L, Hemley S. Inwardly rectifying potassium channel 4.1 expression in post-traumatic syringomyelia. Neuroscience. 2016;317:23-35 pubmed publisher
Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, et al. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016;7:10332 pubmed publisher
Bavetsias V, Lanigan R, Ruda G, Atrash B, McLaughlin M, Tumber A, et al. 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J Med Chem. 2016;59:1388-409 pubmed publisher
Srinivasan R, Henley B, Henderson B, Indersmitten T, Cohen B, Kim C, et al. Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. J Neurosci. 2016;36:65-79 pubmed publisher
Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, et al. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells. Oncogene. 2016;35:4256-68 pubmed publisher
Tan J, Pieper K, Piccoli L, Abdi A, Perez M, Geiger R, et al. A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens. Nature. 2016;529:105-109 pubmed publisher
Ko J, Lee H, Jeong H, Kim M, Wee W, Yoon S, et al. Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye. Proc Natl Acad Sci U S A. 2016;113:158-63 pubmed publisher
Sharpe M, Baskin D. Monoamine oxidase B levels are highly expressed in human gliomas and are correlated with the expression of HiF-1α and with transcription factors Sp1 and Sp3. Oncotarget. 2016;7:3379-93 pubmed publisher
Soendergaard C, Kvist P, Seidelin J, Pelzer H, Nielsen O. Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes. J Gastroenterol. 2016;51:796-807 pubmed publisher
Iaci J, Parry T, Huang Z, Pavlopoulos E, Finklestein S, Ren J, et al. An optimized dosing regimen of cimaglermin (neuregulin 1β3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats. J Neurosci Res. 2016;94:253-65 pubmed publisher
Pinho B, Reis S, Guedes Dias P, Leitão Rocha A, Quintas C, Valentão P, et al. Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson's disease. Pharmacol Res. 2016;103:328-39 pubmed publisher
Nakamura Y, Kitada M, Satoh F, Maekawa T, Morimoto R, Yamazaki Y, et al. Intratumoral heterogeneity of steroidogenesis in aldosterone-producing adenoma revealed by intensive double- and triple-immunostaining for CYP11B2/B1 and CYP17. Mol Cell Endocrinol. 2016;422:57-63 pubmed publisher
Sin J, Andres A, Taylor D, Weston T, Hiraumi Y, Stotland A, et al. Mitophagy is required for mitochondrial biogenesis and myogenic differentiation of C2C12 myoblasts. Autophagy. 2016;12:369-80 pubmed publisher
Garbincius J, Michele D. Dystrophin-glycoprotein complex regulates muscle nitric oxide production through mechanoregulation of AMPK signaling. Proc Natl Acad Sci U S A. 2015;112:13663-8 pubmed publisher
van Geldermalsen M, Wang Q, Nagarajah R, Marshall A, Thoeng A, Gao D, et al. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene. 2016;35:3201-8 pubmed publisher
Murayama M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun. 2015;6:8483 pubmed publisher
Pooryasin A, Fiala A. Identified Serotonin-Releasing Neurons Induce Behavioral Quiescence and Suppress Mating in Drosophila. J Neurosci. 2015;35:12792-812 pubmed publisher
Homa L, Burger L, Cuttitta A, Michele D, Moenter S. Voluntary Exercise Improves Estrous Cyclicity in Prenatally Androgenized Female Mice Despite Programming Decreased Voluntary Exercise: Implications for Polycystic Ovary Syndrome (PCOS). Endocrinology. 2015;156:4618-28 pubmed publisher
Ádám C, Fekete A, Bőgel G, Németh Z, Tőkési N, Ovádi J, et al. Accumulation of the PX domain mutant Frank-ter Haar syndrome protein Tks4 in aggresomes. Cell Commun Signal. 2015;13:33 pubmed publisher
Otaka K, Hiradate Y, Kobayashi N, Shirakata Y, Tanemura K. Distribution of the sex chromosome during mouse spermatogenesis in testis tissue sections. J Reprod Dev. 2015;61:375-81 pubmed publisher
Ufimtseva E. Mycobacterium-Host Cell Relationships in Granulomatous Lesions in a Mouse Model of Latent Tuberculous Infection. Biomed Res Int. 2015;2015:948131 pubmed publisher
Choi S, Gonen A, Diehl C, Kim J, Almazan F, Witztum J, et al. SYK regulates macrophage MHC-II expression via activation of autophagy in response to oxidized LDL. Autophagy. 2015;11:785-95 pubmed publisher
Dorgau B, Herrling R, Schultz K, Greb H, Segelken J, Ströh S, et al. Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions. J Comp Neurol. 2015;523:2062-81 pubmed publisher
Gómez Sánchez R, Pizarro Estrella E, Yakhine Diop S, Rodríguez Arribas M, Bravo San Pedro J, Fuentes J, et al. Routine Western blot to check autophagic flux: cautions and recommendations. Anal Biochem. 2015;477:13-20 pubmed publisher
Riabinina O, Luginbuhl D, Marr E, Liu S, Wu M, Luo L, et al. Improved and expanded Q-system reagents for genetic manipulations. Nat Methods. 2015;12:219-22, 5 p following 222 pubmed publisher
Matusek T, Wendler F, Polès S, Pizette S, D Angelo G, Fürthauer M, et al. The ESCRT machinery regulates the secretion and long-range activity of Hedgehog. Nature. 2014;516:99-103 pubmed publisher
Petridou N, Skourides P. FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis. Nat Commun. 2014;5:5240 pubmed publisher
Di Prisco G, Huang W, Buffington S, Hsu C, Bonnen P, Placzek A, et al. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2?. Nat Neurosci. 2014;17:1073-82 pubmed publisher
Pratt S, Shah S, Ward C, Kerr J, Stains J, Lovering R. Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury. Cell Mol Life Sci. 2015;72:153-64 pubmed publisher
Blom C, Mårtensson L, Dahlin L. Nerve injury-induced c-Jun activation in Schwann cells is JNK independent. Biomed Res Int. 2014;2014:392971 pubmed publisher
Nishimoto Y, Nakagawa S, Hirose T, Okano H, Takao M, Shibata S, et al. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain. 2013;6:31 pubmed publisher
Roher A, Cribbs D, Kim R, Maarouf C, Whiteside C, Kokjohn T, et al. Bapineuzumab alters a? composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy. PLoS ONE. 2013;8:e59735 pubmed publisher
Kang J, Lee B, Kim J, Yoo D, Cho W, Kim S, et al. Granulocyte colony-stimulating factor minimizes negative remodeling of decellularized small diameter vascular graft conduits but not medial degeneration. Ann Vasc Surg. 2013;27:487-96 pubmed publisher
Brus M, Meurisse M, Gheusi G, Keller M, Lledo P, Levy F. Dynamics of olfactory and hippocampal neurogenesis in adult sheep. J Comp Neurol. 2013;521:169-88 pubmed publisher
Lee J, Cummings B, Martin E, Sharp J, Graham J, Stanhope K, et al. Glucose sensing by gut endocrine cells and activation of the vagal afferent pathway is impaired in a rodent model of type 2 diabetes mellitus. Am J Physiol Regul Integr Comp Physiol. 2012;302:R657-66 pubmed publisher
Seiler D, Rouquette J, Schmid V, Strickfaden H, Ottmann C, Drexler G, et al. Double-strand break-induced transcriptional silencing is associated with loss of tri-methylation at H3K4. Chromosome Res. 2011;19:883-99 pubmed publisher
Orsburn B, Escudero B, Prakash M, Gesheva S, Liu G, Huso D, et al. Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1. Mol Cell Biol. 2010;30:2341-52 pubmed publisher
Hol J, Wilhelmsen L, Haraldsen G. The murine IL-8 homologues KC, MIP-2, and LIX are found in endothelial cytoplasmic granules but not in Weibel-Palade bodies. J Leukoc Biol. 2010;87:501-8 pubmed publisher
Mezaki Y, Yamaguchi N, Yoshikawa K, Miura M, Imai K, Itoh H, et al. Insoluble, speckled cytosolic distribution of retinoic acid receptor alpha protein as a marker of hepatic stellate cell activation in vitro. J Histochem Cytochem. 2009;57:687-99 pubmed publisher
Varayoud J, Ramos J, Bosquiazzo V, Muñoz de Toro M, Luque E. Developmental exposure to Bisphenol a impairs the uterine response to ovarian steroids in the adult. Endocrinology. 2008;149:5848-60 pubmed publisher
Svensson A, Norrby M, Libelius R, Tagerud S. Secreted frizzled related protein 1 (Sfrp1) and Wnt signaling in innervated and denervated skeletal muscle. J Mol Histol. 2008;39:329-37 pubmed publisher
Hamazaki Y, Fujita H, Kobayashi T, Choi Y, Scott H, Matsumoto M, et al. Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Nat Immunol. 2007;8:304-11 pubmed
product information
Product Type :
Secondary Antibody
Product Name :
Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
Catalog # :
A-11034
Quantity :
1 mg
Price :
US 239
Clonality :
Polyclonal
Purity :
purified
Host :
Goat
Reactivity :
Rabbit
Applications :
Flow Cytometry: 1-10 µg/mL, Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL
Species :
Rabbit
Isotype :
IgG
Storage :
4° C, store in dark
Description :
Anti-Rabbit secondary antibodies are affinity-purified antibodies with well-characterized specificity for rabbit immunoglobulins and are useful in the detection, sorting or purification of its specified target. Secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody. Most commonly, secondary antibodies are generated by immunizing the host animal with a pooled population of immunoglobulins from the target species and can be further purified and modified (i.e. immunoaffinity chromatography, antibody fragmentation, label conjugation, etc.) to generate highly specific reagents.
Immunogen :
Gamma Immunoglobins Heavy and Light chains
Format :
liquid
Applications w/Dilutions :
Flow Cytometry: 1-10 µg/mL, Immunocytochemistry: 1-10 µg/mL, Immunofluorescence: 1-10 µg/mL
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA