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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
secondary antibody
product name :
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
catalog :
A-11008
quantity :
1 mg
price :
US 196
more info or order :
citations: 734
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; malaria parasite P. falciparum; fig 2d
Galaway F, Drought L, Fala M, Cross N, Kemp A, Rayner J, et al. P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5. Nat Commun. 2017;8:14333 pubmed publisher
Strah N, Romano G, Introna C, Klima R, Marzullo M, Ciapponi L, et al. TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles. BMC Biol. 2020;18:34 pubmed publisher
Winter R, Tian Y, Caldwell F, Seeto W, Koehler J, Pascoe D, et al. Cell engraftment, vascularization, and inflammation after treatment of equine distal limb wounds with endothelial colony forming cells encapsulated within hydrogel microspheres. BMC Vet Res. 2020;16:43 pubmed publisher
Alexandrova J, Piñeiro D, Jukes Jones R, Mordue R, Stoneley M, Willis A. Full-length NF-κB repressing factor contains an XRN2 binding domain. Biochem J. 2020;477:773-786 pubmed publisher
Abdelmoez A, Sardón Puig L, Smith J, Gabriel B, Savikj M, Dollet L, et al. Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism. Am J Physiol Cell Physiol. 2020;318:C615-C626 pubmed publisher
Alshafie W, Francis V, Bednarz K, Pan Y, Stroh T, McPherson P. Regulated resurfacing of a somatostatin receptor storage compartment fine-tunes pituitary secretion. J Cell Biol. 2020;219: pubmed publisher
Avila J, Kiprowska M, Jean Louis T, Rockwell P, Figueiredo Pereira M, Serrano P. PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice. Brain Behav. 2020;10:e01465 pubmed publisher
Klein S, Hesselmann F, Djeljadini S, Berger T, Thiebes A, Schmitz Rode T, et al. EndOxy: Dynamic Long-Term Evaluation of Endothelialized Gas Exchange Membranes for a Biohybrid Lung. Ann Biomed Eng. 2020;48:747-756 pubmed publisher
Shin J, Kong C, Lee J, Choi B, Sim J, Koh C, et al. Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model. Alzheimers Res Ther. 2019;11:110 pubmed publisher
Campbell J, Habibalahi A, Mahbub S, Gosnell M, Anwer A, Paton S, et al. Non-destructive, label free identification of cell cycle phase in cancer cells by multispectral microscopy of autofluorescence. BMC Cancer. 2019;19:1242 pubmed publisher
Jeon S, Ahn J, Halder D, Cho H, Lim J, Jun S, et al. TIPRL potentiates survival of lung cancer by inducing autophagy through the eIF2α-ATF4 pathway. Cell Death Dis. 2019;10:959 pubmed publisher
Stoyas C, Bushart D, Switonski P, Ward J, Alaghatta A, Tang M, et al. Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7. Neuron. 2019;: pubmed publisher
Cárdenas H, Jiang G, Thomes Pepin J, Parker J, Condello S, Nephew K, et al. Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer. NPJ Precis Oncol. 2019;3:32 pubmed publisher
Long M, Zhao Y, Aye Y. Clofarabine Commandeers the RNR-α-ZRANB3 Nuclear Signaling Axis. Cell Chem Biol. 2019;: pubmed publisher
Foxall E, Staszowska A, Hirvonen L, Georgouli M, Ciccioli M, Rimmer A, et al. PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Rep. 2019;29:3385-3393.e6 pubmed publisher
Perri A, Agosti V, Olivo E, Concolino A, Angelis M, Tammè L, et al. Histone proteomics reveals novel post-translational modifications in breast cancer. Aging (Albany NY). 2019;11:11722-11755 pubmed publisher
Woo Y, Kim S, Suh B, Kwak Y, Jung H, Nhung T, et al. Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis. elife. 2019;8: pubmed publisher
Jung Y, Kennedy A, Chiu H, Mohammad F, Claridge Chang A, Anderson D. Neurons that Function within an Integrator to Promote a Persistent Behavioral State in Drosophila. Neuron. 2019;: pubmed publisher
Ferreira Fernandes E, Pinto Correia B, Quintino C, Remondes M. A Gradient of Hippocampal Inputs to the Medial Mesocortex. Cell Rep. 2019;29:3266-3279.e3 pubmed publisher
DeOcesano Pereira C, Machado R, De Jesus Ferreira H, Marchini T, Pereira T, Carreira A, et al. Functional impact of the long non-coding RNA MEG3 deletion by CRISPR/Cas9 in the human triple negative metastatic Hs578T cancer cell line. Oncol Lett. 2019;18:5941-5951 pubmed publisher
Davaadelger B, Choi M, Singhal H, Clare S, Khan S, Kim J. BRCA1 mutation influences progesterone response in human benign mammary organoids. Breast Cancer Res. 2019;21:124 pubmed publisher
Wang L, Shen E, Luo L, Rabe H, Wang Q, Yin J, et al. Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor. Cell Rep. 2019;29:1848-1861.e6 pubmed publisher
Abaffy P, Tomankova S, Naraine R, Kubista M, Sindelka R. The role of nitric oxide during embryonic wound healing. BMC Genomics. 2019;20:815 pubmed publisher
Wang S, Han L, Han J, Li P, Ding Q, Zhang Q, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019;15:1223-1231 pubmed publisher
Higuchi C, Yamamoto M, Shin S, Miyamoto K, Matsumoto K. Perturbation of maternal PIASy abundance disrupts zygotic genome activation and embryonic development via SUMOylation pathway. Biol Open. 2019;8: pubmed publisher
Olivier S, Leclerc J, Grenier A, Foretz M, Tamburini J, Viollet B. AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells. Int J Mol Sci. 2019;20: pubmed publisher
Lin S, Huang C, Sun J, Bollt O, Wang X, Martine E, et al. The mitochondrial deoxyguanosine kinase is required for cancer cell stemness in lung adenocarcinoma. EMBO Mol Med. 2019;11:e10849 pubmed publisher
Joshi D, Zhang C, Babujee L, Vevea J, August B, Sheng Z, et al. Inappropriate Intrusion of an Axonal Mitochondrial Anchor into Dendrites Causes Neurodegeneration. Cell Rep. 2019;29:685-696.e5 pubmed publisher
Conejeros I, Velasquez Z, Grob D, Zhou E, Salecker H, Hermosilla C, et al. Histone H2A and Bovine Neutrophil Extracellular Traps Induce Damage of Besnoitia besnoiti-Infected Host Endothelial Cells but Fail to Affect Total Parasite Proliferation. Biology (Basel). 2019;8: pubmed publisher
Faust J, Millis B, Tyska M. Profilin-Mediated Actin Allocation Regulates the Growth of Epithelial Microvilli. Curr Biol. 2019;29:3457-3465.e3 pubmed publisher
Ramon Mateu J, Ellison S, Angelini T, Martindale M. Regeneration in the ctenophore Mnemiopsis leidyi occurs in the absence of a blastema, requires cell division, and is temporally separable from wound healing. BMC Biol. 2019;17:80 pubmed publisher
Zhu L, Liu H, Lu F, Yang J, Byzova T, Qin J. Structural Basis of Paxillin Recruitment by Kindlin-2 in Regulating Cell Adhesion. Structure. 2019;27:1686-1697.e5 pubmed publisher
Billmyre K, Cahoon C, Heenan G, Wesley E, Yu Z, Unruh J, et al. X chromosome and autosomal recombination are differentially sensitive to disruptions in SC maintenance. Proc Natl Acad Sci U S A. 2019;116:21641-21650 pubmed publisher
Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, et al. A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome. elife. 2019;8: pubmed publisher
Mohammad G, Radhakrishnan R, Kowluru R. Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2019;60:3943-3951 pubmed publisher
Morishita H, Zhao Y, Tamura N, Nishimura T, Kanda Y, Sakamaki Y, et al. A critical role of VMP1 in lipoprotein secretion. elife. 2019;8: pubmed publisher
van Senten J, Bebelman M, Fan T, Heukers R, Bergkamp N, van Gasselt P, et al. The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties. J Biol Chem. 2019;294:16297-16308 pubmed publisher
Fillatre J, Fauny J, Fels J, Li C, Goll M, Thisse C, et al. TEADs, Yap, Taz, Vgll4s transcription factors control the establishment of Left-Right asymmetry in zebrafish. elife. 2019;8: pubmed publisher
Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
Selvaraj S, Dhoke N, Kiley J, Mateos Aierdi A, Tungtur S, Mondragón González R, et al. Gene Correction of LGMD2A Patient-Specific iPSCs for the Development of Targeted Autologous Cell Therapy. Mol Ther. 2019;27:2147-2157 pubmed publisher
Bayles I, Krajewska M, Pontius W, Saiakhova A, Morrow J, Bartels C, et al. Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma. J Clin Invest. 2019;129:4377-4392 pubmed publisher
Corkins M, Krneta Stankic V, Kloc M, McCrea P, Gladden A, Miller R. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14:e0221698 pubmed publisher
Levy D, de Melo T, Oliveira B, Paz J, de Freitas F, Reichert C, et al. 7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line. Biochem Biophys Rep. 2019;19:100604 pubmed publisher
Heijink A, Everts M, Honeywell M, Richards R, Kok Y, de Vries E, et al. Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity. Cell Rep. 2019;28:2345-2357.e5 pubmed publisher
Panier S, Maric M, Hewitt G, Mason Osann E, Gali H, Dai A, et al. SLX4IP Antagonizes Promiscuous BLM Activity during ALT Maintenance. Mol Cell. 2019;76:27-43.e11 pubmed publisher
Ramaekers A, Claeys A, Kapun M, Mouchel Vielh E, Potier D, Weinberger S, et al. Altering the Temporal Regulation of One Transcription Factor Drives Evolutionary Trade-Offs between Head Sensory Organs. Dev Cell. 2019;50:780-792.e7 pubmed publisher
Saenz F, Ory V, Schmidt M, Kallakury B, Mueller S, Furth P, et al. Depletion of the Transcriptional Coactivator Amplified in Breast Cancer 1 (AIB1) Uncovers Functionally Distinct Subpopulations in Triple-Negative Breast Cancer. Neoplasia. 2019;21:963-973 pubmed publisher
Rockfield S, Kee Y, Nanjundan M. Chronic iron exposure and c-Myc/H-ras-mediated transformation in fallopian tube cells alter the expression of EVI1, amplified at 3q26.2 in ovarian cancer. Oncogenesis. 2019;8:46 pubmed publisher
Holt L, Hernandez R, Pacheco N, Torres Ceja B, Hossain M, Olsen M. Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1. elife. 2019;8: pubmed publisher
Rutowicz K, Lirski M, Mermaz B, Teano G, Schubert J, Mestiri I, et al. Linker histones are fine-scale chromatin architects modulating developmental decisions in Arabidopsis. Genome Biol. 2019;20:157 pubmed publisher
Ming Yan Y, Jing Z, Shu Qin G, Xiao Liang B, Zhi Hong L, Xue Z. Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway. Biosci Rep. 2019;39: pubmed publisher
Joyce M, Berry Wynne K, Dos Santos T, Addison W, McFarlane N, Hobman T, et al. HCV and flaviviruses hijack cellular mechanisms for nuclear STAT2 degradation: Up-regulation of PDLIM2 suppresses the innate immune response. PLoS Pathog. 2019;15:e1007949 pubmed publisher
Lee J, Kang H. Hypoxia Promotes Vascular Smooth Muscle Cell Proliferation through microRNA-Mediated Suppression of Cyclin-Dependent Kinase Inhibitors. Cells. 2019;8: pubmed publisher
Pajak A, Laine I, Clemente P, El Fissi N, Schober F, Maffezzini C, et al. Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo. PLoS Genet. 2019;15:e1008240 pubmed publisher
Tsujioka H, Yamashita T. Comparison of gene expression profile of the spinal cord of sprouting-capable neonatal and sprouting-incapable adult mice. BMC Genomics. 2019;20:619 pubmed publisher
Ou H, Kim C, Uszkoreit S, Wickström S, Schumacher B. Somatic Niche Cells Regulate the CEP-1/p53-Mediated DNA Damage Response in Primordial Germ Cells. Dev Cell. 2019;50:167-183.e8 pubmed publisher
Laird J, Gardner S, Kopel A, Kerov V, Lee A, Baker S. Rescue of Rod Synapses by Induction of Cav Alpha 1F in the Mature Cav1.4 Knock-Out Mouse Retina. Invest Ophthalmol Vis Sci. 2019;60:3150-3161 pubmed publisher
Vo D, Karanam N, Ding L, Saha D, Yordy J, Giri U, et al. miR-125a-5p Functions as Tumor Suppressor microRNA And Is a Marker of Locoregional Recurrence And Poor prognosis in Head And Neck Cancer. Neoplasia. 2019;21:849-862 pubmed publisher
Tocci P, Cianfrocca R, Di Castro V, Rosanò L, Sacconi A, Donzelli S, et al. β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer. Nat Commun. 2019;10:3196 pubmed publisher
Park S, Kim R, Park B, Lee S, Choi S, Park J, et al. Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction. Nat Commun. 2019;10:3123 pubmed publisher
Lee S, Kim J. Basal Forebrain Cholinergic-induced Activation of Cholecystokinin Inhibitory Neurons in the Basolateral Amygdala. Exp Neurobiol. 2019;28:320-328 pubmed publisher
Shinoda S, Kitagawa S, Nakagawa S, Wei F, Tomizawa K, Araki K, et al. Mammalian NSUN2 introduces 5-methylcytidines into mitochondrial tRNAs. Nucleic Acids Res. 2019;47:8734-8745 pubmed publisher
Evans H, Benetatos J, van Roijen M, Bodea L, Götz J. Decreased synthesis of ribosomal proteins in tauopathy revealed by non-canonical amino acid labelling. EMBO J. 2019;38:e101174 pubmed publisher
McLaughlin R, He J, van der Noord V, Redel J, Foekens J, Martens J, et al. A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy. Breast Cancer Res. 2019;21:77 pubmed publisher
Wang H, Xiang D, Liu B, He A, Randle H, Zhang K, et al. Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer. Cell. 2019;178:135-151.e19 pubmed publisher
Ding K, Han Y, Seid T, Buser C, Karigo T, Zhang S, et al. Imaging neuropeptide release at synapses with a genetically engineered reporter. elife. 2019;8: pubmed publisher
Katsuno T, Belyantseva I, Cartagena Rivera A, Ohta K, Crump S, Petralia R, et al. TRIOBP-5 sculpts stereocilia rootlets and stiffens supporting cells enabling hearing. JCI Insight. 2019;4: pubmed publisher
Shah B, Shimell J, Bamji S. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J Cell Sci. 2019;: pubmed publisher
Bolger Munro M, Choi K, Scurll J, Abraham L, Chappell R, Sheen D, et al. Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation. elife. 2019;8: pubmed publisher
Hammerschmidt P, Ostkotte D, Nolte H, Gerl M, Jais A, Brunner H, et al. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019;177:1536-1552.e23 pubmed publisher
Gambarotto D, Pennetier C, Ryniawec J, Buster D, Gogendeau D, Goupil A, et al. Plk4 Regulates Centriole Asymmetry and Spindle Orientation in Neural Stem Cells. Dev Cell. 2019;: pubmed publisher
Octeau J, Gangwani M, Allam S, Tran D, Huang S, Hoang Trong T, et al. Transient, Consequential Increases in Extracellular Potassium Ions Accompany Channelrhodopsin2 Excitation. Cell Rep. 2019;27:2249-2261.e7 pubmed publisher
Fiorucci A, Bourbousse C, Concia L, Rougée M, Deton Cabanillas A, Zabulon G, et al. Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in H3K4me3 independently from histone H2B monoubiquitination. Genome Biol. 2019;20:100 pubmed publisher
Menzorov A, Orishchenko K, Fishman V, Shevtsova A, Mungalov R, Pristyazhnyuk I, et al. Targeted genomic integration of EGFP under tubulin beta 3 class III promoter and mEos2 under tryptophan hydroxylase 2 promoter does not produce sufficient levels of reporter gene expression. J Cell Biochem. 2019;: pubmed publisher
Geister K, López Jiménez A, Houghtaling S, Ho T, Vanacore R, Beier D. Loss of function of Colgalt1 disrupts collagen post-translational modification and causes musculoskeletal defects. Dis Model Mech. 2019;: pubmed publisher
Dabral S, Muecke C, Valasarajan C, Schmoranzer M, Wietelmann A, Semenza G, et al. A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension. Nat Commun. 2019;10:2130 pubmed publisher
Hashimoto H, Wang Z, Garry G, Malladi V, Botten G, Ye W, et al. Cardiac Reprogramming Factors Synergistically Activate Genome-wide Cardiogenic Stage-Specific Enhancers. Cell Stem Cell. 2019;: pubmed publisher
Yan Y, Yu H, Sun L, Liu H, Wang C, Wei X, et al. Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract. Aging (Albany NY). 2019;11:2699-2723 pubmed publisher
Cho C, Wang Y, Smallwood P, Williams J, Nathans J. Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers. elife. 2019;8: pubmed publisher
Allden S, Ogger P, Ghai P, McErlean P, Hewitt R, Toshner R, et al. The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019;: pubmed publisher
Walker M, Lindner S. Ribozyme-mediated, multiplex CRISPR gene editing and CRISPR interference (CRISPRi) in rodent-infectious Plasmodium yoelii. J Biol Chem. 2019;294:9555-9566 pubmed publisher
Reis L, Adamoski D, Ornitz Oliveira Souza R, Rodrigues Ascenção C, Sousa de Oliveira K, Correa da Silva F, et al. Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells. J Biol Chem. 2019;294:9342-9357 pubmed publisher
Cook B, Rafiq R, Lee H, Banks K, El Debs M, Chiaravalli J, et al. Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell Chem Biol. 2019;: pubmed publisher
Chino H, Hatta T, Natsume T, Mizushima N. Intrinsically Disordered Protein TEX264 Mediates ER-phagy. Mol Cell. 2019;74:909-921.e6 pubmed publisher
Yamamoto S, Kitagawa D. Self-organization of Plk4 regulates symmetry breaking in centriole duplication. Nat Commun. 2019;10:1810 pubmed publisher
Connahs H, Tlili S, van Creij J, Loo T, Banerjee T, Saunders T, et al. Distal-less activates butterfly eyespots consistent with a reaction diffusion process. Development. 2019;: pubmed publisher
Chan E, Shibue T, McFarland J, Gaeta B, Ghandi M, Dumont N, et al. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019;568:551-556 pubmed publisher
Ding X, Jiang X, Tian R, Zhao P, Li L, Wang X, et al. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;:1-13 pubmed publisher
Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, et al. Autophagy regulates lipid metabolism through selective turnover of NCoR1. Nat Commun. 2019;10:1567 pubmed publisher
Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher
Lim S, Hermance N, Mudianto T, Mustaly H, Mauricio I, Vittoria M, et al. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nat Commun. 2019;10:1547 pubmed publisher
Sivandzade F, Cucullo L. Assessing the protective effect of rosiglitazone against electronic cigarette/tobacco smoke-induced blood-brain barrier impairment. BMC Neurosci. 2019;20:15 pubmed publisher
Siddharth S, Muniraj N, Saxena N, Sharma D. Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of Withaferin A in Hepatocellular Carcinoma. Cancers (Basel). 2019;11: pubmed publisher
Edfawy M, Guedes J, Pereira M, Laranjo M, Carvalho M, Gao X, et al. Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice. Nat Commun. 2019;10:1431 pubmed publisher
Qian Q, Zhang Z, Li M, Savage K, Cheng D, Rauckhorst A, et al. Hepatic Lysosomal iNOS Activity Impairs Autophagy in Obesity. Cell Mol Gastroenterol Hepatol. 2019;8:95-110 pubmed publisher
Goldstein R, Barkai O, Íñigo Portugués A, Katz B, Lev S, Binshtok A. Location and Plasticity of the Sodium Spike Initiation Zone in Nociceptive Terminals In Vivo. Neuron. 2019;102:801-812.e5 pubmed publisher
Liao W, Overman M, Boutin A, Shang X, Zhao D, Dey P, et al. KRAS-IRF2 Axis Drives Immune Suppression and Immune Therapy Resistance in Colorectal Cancer. Cancer Cell. 2019;35:559-572.e7 pubmed publisher
Astvaldsson A, Hultenby K, Svard S, Jerlström Hultqvist J. Proximity Staining Using Enzymatic Protein Tagging in Diplomonads. mSphere. 2019;4: pubmed publisher
Li X, Deng M, Petrucelli A, Zhu C, Mo J, Zhang L, et al. Viral DNA Binding to NLRC3, an Inhibitory Nucleic Acid Sensor, Unleashes STING, a Cyclic Dinucleotide Receptor that Activates Type I Interferon. Immunity. 2019;50:591-599.e6 pubmed publisher
Vargas J, Wang C, Bunker E, Hao L, Maric D, Schiavo G, et al. Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy. Mol Cell. 2019;74:347-362.e6 pubmed publisher
Turco E, Witt M, Abert C, Bock Bierbaum T, Su M, Trapannone R, et al. FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates. Mol Cell. 2019;74:330-346.e11 pubmed publisher
Crerar H, Scott Solomon E, Bodkin Clarke C, Andreassi C, Hazbon M, Logie E, et al. Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019;102:553-563.e8 pubmed publisher
Guillon J, Petit C, Moreau M, Toutain B, Henry C, Roche H, et al. Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment. Cell Death Dis. 2019;10:199 pubmed publisher
Carim S, Ben El Kadhi K, Yan G, Sweeney S, Hickson G, Carreno S, et al. IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis. Curr Biol. 2019;: pubmed publisher
McDermott L, Weir G, Themistocleous A, Segerdahl A, Blesneac I, Baskozos G, et al. Defining the Functional Role of NaV1.7 in Human Nociception. Neuron. 2019;101:905-919.e8 pubmed publisher
D Aiuto L, Bloom D, Naciri J, Smith A, Edwards T, McClain L, et al. Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells. J Virol. 2019;93: pubmed publisher
Nestor Bergmann A, Stooke Vaughan G, Goddard G, Starborg T, Jensen O, Woolner S. Decoupling the Roles of Cell Shape and Mechanical Stress in Orienting and Cueing Epithelial Mitosis. Cell Rep. 2019;26:2088-2100.e4 pubmed publisher
Felipe Abrio B, Verdugo Sivianes E, Saez C, Carnero A. Loss of MYBBP1A Induces Cancer Stem Cell Activity in Renal Cancer. Cancers (Basel). 2019;11: pubmed publisher
Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed publisher
Roux C, Jafari S, Shinde R, Duncan G, Cescon D, Silvester J, et al. Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
Novielli Kuntz N, Jelen M, Barr K, DeLalio L, Feng Q, Isakson B, et al. Ablation of both Cx40 and Panx1 results in similar cardiovascular phenotypes exhibited in Cx40 knockout mice. Biosci Rep. 2019;39: pubmed publisher
Parker K, Fairweather S, Rajendran E, Blume M, McConville M, Broer S, et al. The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family. PLoS Pathog. 2019;15:e1007577 pubmed publisher
Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, et al. Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019;146: pubmed publisher
Kim M, Son D, Shin S, Park D, Byun S, Jung E. Protective effects of Camellia japonica flower extract against urban air pollutants. BMC Complement Altern Med. 2019;19:30 pubmed publisher
Tovini L, McClelland S. Impaired CENP-E Function Renders Large Chromosomes More Vulnerable to Congression Failure. Biomolecules. 2019;9: pubmed publisher
Mengwasser K, Adeyemi R, Leng Y, Choi M, Clairmont C, D Andrea A, et al. Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets. Mol Cell. 2019;73:885-899.e6 pubmed publisher
Patron L, Nagatomo K, Eves D, Imad M, Young K, Torvund M, et al. Cul4 ubiquitin ligase cofactor DCAF12 promotes neurotransmitter release and homeostatic plasticity. J Cell Biol. 2019;218:993-1010 pubmed publisher
Martin J, Muccioli M, Herman K, Finnell R, Plageman T. Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism. Biol Open. 2019;8: pubmed publisher
Agrotis A, Pengo N, Burden J, Ketteler R. Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells. Autophagy. 2019;15:976-997 pubmed publisher
Sellnow R, Newman J, Chambers N, West A, Steece Collier K, Sandoval I, et al. Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia. Acta Neuropathol Commun. 2019;7:8 pubmed publisher
Schips T, Vanhoutte D, Vo A, Correll R, Brody M, Khalil H, et al. Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Nat Commun. 2019;10:76 pubmed publisher
Noseda R, Melo Carrillo A, Nir R, Strassman A, Burstein R. Non-Trigeminal Nociceptive Innervation of the Posterior Dura: Implications to Occipital Headache. J Neurosci. 2019;39:1867-1880 pubmed publisher
Xu X, Chini M, Bitzenhofer S, Hanganu Opatz I. Transient Knock-Down of Prefrontal DISC1 in Immune-Challenged Mice Causes Abnormal Long-Range Coupling and Cognitive Dysfunction throughout Development. J Neurosci. 2019;39:1222-1235 pubmed publisher
Cioni J, Lin J, Holtermann A, Koppers M, Jakobs M, Azizi A, et al. Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons. Cell. 2019;176:56-72.e15 pubmed publisher
Rangaraju V, Lauterbach M, Schuman E. Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity. Cell. 2019;176:73-84.e15 pubmed publisher
Hassan A, Bagu E, Lévesque M, Patten S, Benhadjeba S, Edjekouane L, et al. The 17β-estradiol induced upregulation of the adhesion G-protein coupled receptor (ADGRG7) is modulated by ESRα and SP1 complex. Biol Open. 2019;8: pubmed publisher
Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher
Engel M, Gee Y, Cross D, Maccarone A, Heng B, Hulme A, et al. Novel dual-action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine-specific histone demethylase 1A inhibitor. J Neurochem. 2019;149:535-550 pubmed publisher
Stojic A, Bojcevski J, Williams S, Bas Orth C, Nessler S, Linington C, et al. Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis. Glia. 2019;67:512-524 pubmed publisher
Volkmar N, Thezenas M, Louie S, Juszkiewicz S, Nomura D, Hegde R, et al. The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis. J Cell Sci. 2019;132: pubmed publisher
Smyrek I, Mathew B, Fischer S, Lissek S, Becker S, Stelzer E. E-cadherin, actin, microtubules and FAK dominate different spheroid formation phases and important elements of tissue integrity. Biol Open. 2019;8: pubmed publisher
Lambert J, Picaud S, Fujisawa T, Hou H, Savitsky P, Uusküla Reimand L, et al. Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol Cell. 2019;73:621-638.e17 pubmed publisher
Kim Y, Furman C, Manhart C, Alani E, Finkelstein I. Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex. Nucleic Acids Res. 2019;47:1823-1835 pubmed publisher
Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, et al. Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells. EMBO J. 2019;38: pubmed publisher
Rai S, Arasteh M, Jefferson M, Pearson T, Wang Y, Zhang W, et al. The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis. Autophagy. 2019;15:599-612 pubmed publisher
Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
van Duinen V, Zhu D, Ramakers C, van Zonneveld A, Vulto P, Hankemeier T. Perfused 3D angiogenic sprouting in a high-throughput in vitro platform. Angiogenesis. 2019;22:157-165 pubmed publisher
Ardelt M, Frohlich T, Martini E, Muller M, Kanitz V, Atzberger C, et al. Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy. Hepatology. 2019;69:376-393 pubmed publisher
Raikwar S, Thangavel R, Dubova I, Selvakumar G, Ahmed M, Kempuraj D, et al. Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer's Disease Therapeutic Target. Mol Neurobiol. 2019;56:378-393 pubmed publisher
Liu Z, Zheng Z, Qi J, Wang J, Zhou Q, Hu F, et al. CD24 identifies nucleus pulposus progenitors/notochordal cells for disc regeneration. J Biol Eng. 2018;12:35 pubmed publisher
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nat Commun. 2018;9:5193 pubmed publisher
Lee J, Heo J, Kang H. miR-92b-3p-TSC1 axis is critical for mTOR signaling-mediated vascular smooth muscle cell proliferation induced by hypoxia. Cell Death Differ. 2018;: pubmed publisher
Ventimiglia L, Cuesta Geijo M, Martinelli N, Caballe A, Macheboeuf P, Miguet N, et al. CC2D1B Coordinates ESCRT-III Activity during the Mitotic Reformation of the Nuclear Envelope. Dev Cell. 2018;47:547-563.e6 pubmed publisher
Svancarova P, Betakova T. Conserved methionine 165 of matrix protein contributes to the nuclear import and is essential for influenza A virus replication. Virol J. 2018;15:187 pubmed publisher
Lee C, Cheng Y, Chang C, Lin C, Chang J. Alpha-tubulin acetyltransferase/MEC-17 regulates cancer cell migration and invasion through epithelial-mesenchymal transition suppression and cell polarity disruption. Sci Rep. 2018;8:17477 pubmed publisher
Danesi C, Achuta V, Corcoran P, Peteri U, Turconi G, Matsui N, et al. Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein. Stem Cell Reports. 2018;11:1449-1461 pubmed publisher
Pfaller C, Donohue R, Nersisyan S, Brodsky L, Cattaneo R. Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1p150. PLoS Biol. 2018;16:e2006577 pubmed publisher
Abdullah A, Zhang M, Frugier T, Bedoui S, Taylor J, Crack P. STING-mediated type-I interferons contribute to the neuroinflammatory process and detrimental effects following traumatic brain injury. J Neuroinflammation. 2018;15:323 pubmed publisher
Griffiths P, Lolait S, Pearce L, McBryde F, Paton J, O Carroll A. Blockade of Rostral Ventrolateral Medulla Apelin Receptors Does Not Attenuate Arterial Pressure in SHR and L-NAME-Induced Hypertensive Rats. Front Physiol. 2018;9:1488 pubmed publisher
Zhang S, Shrestha C, Kopp B. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function. Sci Rep. 2018;8:17066 pubmed publisher
Arnandis T, Monteiro P, Adams S, Bridgeman V, Rajeeve V, Gadaleta E, et al. Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion. Dev Cell. 2018;47:409-424.e9 pubmed publisher
Khan M, Pace Asciak C, Al Hassan J, Afzal M, Liu Y, Oommen S, et al. Furanoid F-Acid F6 Uniquely Induces NETosis Compared to C16 and C18 Fatty Acids in Human Neutrophils. Biomolecules. 2018;8: pubmed publisher
Zimmerman S, Besio R, Heard Lipsmeyer M, Dimori M, Castagnola P, Swain F, et al. Expression characterization and functional implication of the collagen-modifying Leprecan proteins in mouse gonadal tissue and mature sperm. AIMS Genet. 2018;5:24-40 pubmed publisher
Rodriguez Gutierrez D, Eid W, Biason Lauber A. A Human Gonadal Cell Model From Induced Pluripotent Stem Cells. Front Genet. 2018;9:498 pubmed publisher
Betten R, Scharner B, Probst S, Edemir B, Wolff N, Langelueddecke C, et al. Tonicity inversely modulates lipocalin-2 (Lcn2/24p3/NGAL) receptor (SLC22A17) and Lcn2 expression via Wnt/β-catenin signaling in renal inner medullary collecting duct cells: implications for cell fate and bacterial infection. Cell Commun Signal. 2018;16:74 pubmed publisher
McNair K, Forrest C, Vincenten M, Darlington L, Stone T. Serine protease modulation of Dependence Receptors and EMT protein expression. Cancer Biol Ther. 2018;:1-19 pubmed publisher
Beckwitt C, Clark A, Ma B, Whaley D, OLTVAI Z, Wells A. Statins attenuate outgrowth of breast cancer metastases. Br J Cancer. 2018;119:1094-1105 pubmed publisher
Malcov Brog H, Alpert A, Golan T, Parikh S, Nordlinger A, Netti F, et al. UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Mol Cell. 2018;72:444-456.e7 pubmed publisher
Barikbin R, Berkhout L, Bolik J, Schmidt Arras D, Ernst T, Ittrich H, et al. Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2-/- mice. Sci Rep. 2018;8:16238 pubmed publisher
Fukunaga T, Fujita Y, Kishima H, Yamashita T. Methylation dependent down-regulation of G0S2 leads to suppression of invasion and improved prognosis of IDH1-mutant glioma. PLoS ONE. 2018;13:e0206552 pubmed publisher
Lagalice L, Pichon J, Gougeon E, Soussi S, Deniaud J, Ledevin M, et al. Satellite cells fail to contribute to muscle repair but are functional in Pompe disease (glycogenosis type II). Acta Neuropathol Commun. 2018;6:116 pubmed publisher
Gonzalez L, Macdonald M, Deng Y, Trigatti B. Hyperglycemia Aggravates Diet-Induced Coronary Artery Disease and Myocardial Infarction in SR-B1-Knockout/ApoE-Hypomorphic Mice. Front Physiol. 2018;9:1398 pubmed publisher
Gasperini L, Rossi A, Cornella N, Peroni D, Zuccotti P, Potrich V, et al. The hnRNP raly regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization. Mol Biol Cell. 2018;:mbcE18020108 pubmed publisher
Guo Y, Yuan Y, Wu L, Ho T, Jing J, Sugii H, et al. BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair. Bone Res. 2018;6:30 pubmed publisher
Kim H, Kim D, Bae S, Gwak H, Jeon J, Kim J, et al. Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness. Exp Mol Med. 2018;50:137 pubmed publisher
Gordon H, Lusk S, Carney K, Wirick E, Murray B, Kwan K. Hedgehog signaling regulates cell motility and optic fissure and stalk formation during vertebrate eye morphogenesis. Development. 2018;145: pubmed publisher
Mayoral S, Etxeberria A, Shen Y, Chan J. Initiation of CNS Myelination in the Optic Nerve Is Dependent on Axon Caliber. Cell Rep. 2018;25:544-550.e3 pubmed publisher
Li M, Cao L, Xiao N, Tang M, Deng B, Yang T, et al. Hub-organized parallel circuits of central circadian pacemaker neurons for visual photoentrainment in Drosophila. Nat Commun. 2018;9:4247 pubmed publisher
Isakson S, Rizzardi A, Coutts A, Carlson D, Kirstein M, Fisher J, et al. Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Commun Biol. 2018;1:158 pubmed publisher
Martins G, Paredes B, Azevedo C, Sampaio G, Nonaka C, Cavalcante B, et al. Generation of integration-free iPS cell lines from three sickle cell disease patients from the state of Bahia, Brazil. Stem Cell Res. 2018;33:10-14 pubmed publisher
Cheruiyot A, Li S, Nickless A, Roth R, Fitzpatrick J, You Z. Compound C inhibits nonsense-mediated RNA decay independently of AMPK. PLoS ONE. 2018;13:e0204978 pubmed publisher
Bhagwat S, Gigliotti F, Wang J, Wang Z, Notter R, Murphy P, et al. Intrinsic Programming of Alveolar Macrophages for Protective Antifungal Innate Immunity Against Pneumocystis Infection. Front Immunol. 2018;9:2131 pubmed publisher
Tanaka H, Kondo K, Chen X, Homma H, Tagawa K, Kerever A, et al. The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology. Mol Psychiatry. 2018;23:2090-2110 pubmed publisher
Fort L, Batista J, Thomason P, Spence H, Whitelaw J, Tweedy L, et al. Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nat Cell Biol. 2018;20:1159-1171 pubmed publisher
Galagovsky D, Depetris Chauvin A, Manière G, Geillon F, Berthelot Grosjean M, Noirot E, et al. Sobremesa L-type Amino Acid Transporter Expressed in Glia Is Essential for Proper Timing of Development and Brain Growth. Cell Rep. 2018;24:3156-3166.e4 pubmed publisher
Sangalli J, Sampaio R, Del Collado M, da Silveira J, De Bem T, Perecin F, et al. Metabolic gene expression and epigenetic effects of the ketone body β-hydroxybutyrate on H3K9ac in bovine cells, oocytes and embryos. Sci Rep. 2018;8:13766 pubmed publisher
Cooper C, Dutta N, Martin C, Piscione T, Thorner P, Jones N. Characterization of a novel disease-associated mutation within NPHS1 and its effects on nephrin phosphorylation and signaling. PLoS ONE. 2018;13:e0203905 pubmed publisher
Luong B, Schwenk R, Bräutigam J, Muller R, Menche D, Bischoff I, et al. The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen. PLoS ONE. 2018;13:e0203053 pubmed publisher
Nassrallah A, Rougée M, Bourbousse C, Drevensek S, Fonseca S, Iniesto E, et al. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis. elife. 2018;7: pubmed publisher
Baker S, Ledwith M, Mehle A. Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza Polymerase. Cell Rep. 2018;24:2581-2588.e4 pubmed publisher
Wang X, Li Q, Liu C, Hall P, Jiang J, Katchis C, et al. Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration. Cell Rep. 2018;24:2540-2552.e6 pubmed publisher
van den Berg J, G Manjón A, Kielbassa K, Feringa F, Freire R, Medema R. A limited number of double-strand DNA breaks is sufficient to delay cell cycle progression. Nucleic Acids Res. 2018;46:10132-10144 pubmed publisher
Lenos K, Miedema D, Lodestijn S, Nijman L, van den Bosch T, Romero Ros X, et al. Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer. Nat Cell Biol. 2018;20:1193-1202 pubmed publisher
Tekin C, Shi K, Daalhuisen J, Ten Brink M, Bijlsma M, Spek C. PAR1 signaling on tumor cells limits tumor growth by maintaining a mesenchymal phenotype in pancreatic cancer. Oncotarget. 2018;9:32010-32023 pubmed publisher
Zhu B, Rippe C, Holmberg J, Zeng S, Perisic L, Albinsson S, et al. Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP. Sci Rep. 2018;8:13025 pubmed publisher
Chakrabarty P, Li A, Ladd T, Strickland M, Koller E, Burgess J, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. J Exp Med. 2018;215:2247-2264 pubmed publisher
Thomas H, Zhang Y, Stefely J, Veiga S, Thomas G, Kozma S, et al. Mitochondrial Complex I Activity Is Required for Maximal Autophagy. Cell Rep. 2018;24:2404-2417.e8 pubmed publisher
Chow H, Dong B, Valencia C, Zeng C, Koch J, Prudnikova T, et al. Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer. Nat Commun. 2018;9:3473 pubmed publisher
Singh K, Camera E, Krug L, Basu A, Pandey R, Munir S, et al. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin. Nat Commun. 2018;9:3425 pubmed publisher
Walcher J, Ojeda Alonso J, Haseleu J, Oosthuizen M, Rowe A, Bennett N, et al. Specialized mechanoreceptor systems in rodent glabrous skin. J Physiol. 2018;596:4995-5016 pubmed publisher
Arbach H, Harland Dunaway M, Chang J, Wills A. Extreme nuclear branching in healthy epidermal cells of the Xenopus tail fin. J Cell Sci. 2018;131: pubmed publisher
Kwapis J, Alaghband Y, Kramar E, Lopez A, Vogel Ciernia A, White A, et al. Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. Nat Commun. 2018;9:3323 pubmed publisher
Daniel K, Icha J, Horenburg C, Müller D, Norden C, Mansfeld J. Conditional control of fluorescent protein degradation by an auxin-dependent nanobody. Nat Commun. 2018;9:3297 pubmed publisher
Shen C, Li L, Zhao K, Bai L, Wang A, Shu X, et al. Motoneuron Wnts regulate neuromuscular junction development. elife. 2018;7: pubmed publisher
Ravi P, Trivedi D, Hasan G. FMRFa receptor stimulated Ca2+ signals alter the activity of flight modulating central dopaminergic neurons in Drosophila melanogaster. PLoS Genet. 2018;14:e1007459 pubmed publisher
Kim J, Ko M, Gonzales E, Kang R, Kim D, Kim Y, et al. Social support rescues acute stress-induced cognitive impairments by modulating ERK1/2 phosphorylation in adolescent mice. Sci Rep. 2018;8:12003 pubmed publisher
Clarke D, Pearse Y, Kan S, Le S, Sanghez V, Cooper J, et al. Genetically Corrected iPSC-Derived Neural Stem Cell Grafts Deliver Enzyme Replacement to Affect CNS Disease in Sanfilippo B Mice. Mol Ther Methods Clin Dev. 2018;10:113-127 pubmed publisher
Quintana M, Ch ng J, Zandian A, Imam M, Hultenby K, Theisen M, et al. SURGE complex of Plasmodium falciparum in the rhoptry-neck (SURFIN4.2-RON4-GLURP) contributes to merozoite invasion. PLoS ONE. 2018;13:e0201669 pubmed publisher
Schlueter J, Mikawa T. Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers. Cell Rep. 2018;24:1456-1463 pubmed publisher
Lei J, Shao J, Zhang J, IGLESIA M, Chan D, Cao J, et al. Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer. Cell Rep. 2018;24:1434-1444.e7 pubmed publisher
Tseligka E, Sobo K, Stoppini L, Cagno V, Abdul F, Piuz I, et al. A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism. PLoS Pathog. 2018;14:e1007190 pubmed publisher
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
Guner Ataman B, González Rosa J, Shah H, Butty V, Jeffrey S, Abrial M, et al. Failed Progenitor Specification Underlies the Cardiopharyngeal Phenotypes in a Zebrafish Model of 22q11.2 Deletion Syndrome. Cell Rep. 2018;24:1342-1354.e5 pubmed publisher
Viola H, Johnstone V, Adams A, Fletcher S, Hool L. A Morpholino Oligomer Therapy Regime That Restores Mitochondrial Function and Prevents mdx Cardiomyopathy. JACC Basic Transl Sci. 2018;3:391-402 pubmed publisher
Zhang X, Mao G, van den Pol A. Chikungunya-vesicular stomatitis chimeric virus targets and eliminates brain tumors. Virology. 2018;522:244-259 pubmed publisher
Fujiwara Y, Saito M, Robles A, Nishida M, Takeshita F, Watanabe M, et al. A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network. EBioMedicine. 2018;33:33-48 pubmed publisher
Dergilev K, Tsokolaeva Z, Makarevich P, Beloglazova I, Zubkova E, Boldyreva M, et al. C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats. Biomed Res Int. 2018;2018:3536854 pubmed publisher
Li Z, Jella K, Jaafar L, Li S, Park S, Story M, et al. Exposure to galactic cosmic radiation compromises DNA repair and increases the potential for oncogenic chromosomal rearrangement in bronchial epithelial cells. Sci Rep. 2018;8:11038 pubmed publisher
Del Rio C, Cantarero I, Palomares B, Gómez Cañas M, Fernandez Ruiz J, Pavicic C, et al. VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways. Br J Pharmacol. 2018;175:3813-3831 pubmed publisher
Tebaldi T, Zuccotti P, Peroni D, Köhn M, Gasperini L, Potrich V, et al. HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA. Mol Cell. 2018;71:256-270.e10 pubmed publisher
Wickert M, Hildick K, Baillie G, Jelinek R, Aparisi Rey A, Monory K, et al. The F238L Point Mutation in the Cannabinoid Type 1 Receptor Enhances Basal Endocytosis via Lipid Rafts. Front Mol Neurosci. 2018;11:230 pubmed publisher
Sun J, Liu Y, Jia Y, Hao X, Lin W, Tran J, et al. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. elife. 2018;7: pubmed publisher
Malik A, Miguez R, Li X, Ho Y, Feldman E, Barmada S. Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization. elife. 2018;7: pubmed publisher
Shen M, Cao Y, Jiang Y, Wei Y, Liu H. Melatonin protects mouse granulosa cells against oxidative damage by inhibiting FOXO1-mediated autophagy: Implication of an antioxidation-independent mechanism. Redox Biol. 2018;18:138-157 pubmed publisher
Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, et al. Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis. Stem Cell Reports. 2018;11:228-241 pubmed publisher
Lemmens B, Hegarat N, Akopyan K, Sala Gaston J, Bartek J, Hochegger H, et al. DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation. Mol Cell. 2018;71:117-128.e3 pubmed publisher
McCormick C, Waters H, Bezrukov L, Taginya R, Parikh V, Onyekaba G, et al. Subcutaneous adipose tissue imaging of human obesity reveals two types of adipocyte membranes: Insulin-responsive and -nonresponsive. J Biol Chem. 2018;293:14249-14259 pubmed publisher
Rao A, LaBonne C. Histone deacetylase activity has an essential role in establishing and maintaining the vertebrate neural crest. Development. 2018;145: pubmed publisher
Park S, Lee C, Lee J, Park J, Roshandell M, Brennan C, et al. Requirement for and polarized localization of integrin proteins during Drosophila wound closure. Mol Biol Cell. 2018;29:2137-2147 pubmed publisher
Rader E, Naimo M, Ensey J, Baker B. VCAM-1 upregulation accompanies muscle remodeling following resistance-type exercise in Snell dwarf (Pit1dw/dw ) mice. Aging Cell. 2018;17:e12816 pubmed publisher
Warecki B, Sullivan W. Micronuclei Formation Is Prevented by Aurora B-Mediated Exclusion of HP1a from Late-Segregating Chromatin in Drosophila. Genetics. 2018;210:171-187 pubmed publisher
Latomanski E, Newton H. Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain). Autophagy. 2018;14:1710-1725 pubmed publisher
Ridinger J, Koeneke E, Kolbinger F, Koerholz K, Mahboobi S, Hellweg L, et al. Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance. Sci Rep. 2018;8:10039 pubmed publisher
Tamai M, Inukai T, Kojika S, Abe M, Kagami K, Harama D, et al. T315I mutation of BCR-ABL1 into human Philadelphia chromosome-positive leukemia cell lines by homologous recombination using the CRISPR/Cas9 system. Sci Rep. 2018;8:9966 pubmed publisher
Yu Z, Ma J, Li X, Liu Y, Li M, Wang L, et al. Autophagy defects and related genetic variations in renal cell carcinoma with eosinophilic cytoplasmic inclusions. Sci Rep. 2018;8:9972 pubmed publisher
Thangaraj A, Periyasamy P, Liao K, Bendi V, Callen S, Pendyala G, et al. HIV-1 TAT-mediated microglial activation: role of mitochondrial dysfunction and defective mitophagy. Autophagy. 2018;14:1596-1619 pubmed publisher
Chou S, Ko Y, Yang Y, Yarmishyn A, Wu Y, Chen C, et al. Generation of two isogenic human induced pluripotent stem cell lines from a 15 year-old female patient with MERRF syndrome and A8344G mutation of mitochondrial DNA. Stem Cell Res. 2018;30:201-205 pubmed publisher
Martina J, Puertollano R. Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress. J Biol Chem. 2018;293:12525-12534 pubmed publisher
Li R, Johnson L, Kohen C, Tablin F. A novel approach to identifying and quantifying neutrophil extracellular trap formation in septic dogs using immunofluorescence microscopy. BMC Vet Res. 2018;14:210 pubmed publisher
Cai Y, Wang W, Paulucci Holthauzen A, Pan Z. Brain Circuits Mediating Opposing Effects on Emotion and Pain. J Neurosci. 2018;38:6340-6349 pubmed publisher
Park S, Lim J, Ramakrishina S, Kim S, Kim W, Lee J, et al. Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination. Neuron. 2018;99:83-97.e7 pubmed publisher
Zhao D, Feng P, Sun Y, Qin Z, Zhang Z, Tan Y, et al. Cardiac-derived CTRP9 protects against myocardial ischemia/reperfusion injury via calreticulin-dependent inhibition of apoptosis. Cell Death Dis. 2018;9:723 pubmed publisher
Harrison H, Pegg H, Thompson J, Bates C, Shore P. HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells. BMC Cancer. 2018;18:674 pubmed publisher
Schultz L, Haltom J, Almeida M, Wierson W, Solin S, Weiss T, et al. Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation. Dis Model Mech. 2018;11: pubmed publisher
Cruz J, Hupper N, Wilson L, Concannon J, Wang Y, Oberhauser B, et al. Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy. J Biol Chem. 2018;293:11837-11849 pubmed publisher
Worrall J, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, et al. Non-random Mis-segregation of Human Chromosomes. Cell Rep. 2018;23:3366-3380 pubmed publisher
Ihry R, Worringer K, Salick M, Frias E, Ho D, Theriault K, et al. p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells. Nat Med. 2018;24:939-946 pubmed publisher
Zhi H, Gong F, Cheng W, Zhu K, Chen L, Yao Y, et al. Tollip Negatively Regulates Vascular Smooth Muscle Cell-Mediated Neointima Formation by Suppressing Akt-Dependent Signaling. J Am Heart Assoc. 2018;7: pubmed publisher
Liu T, Kong W, Tang X, Xu M, Wang Q, Zhang B, et al. The transcription factor Zfp90 regulates the self-renewal and differentiation of hematopoietic stem cells. Cell Death Dis. 2018;9:677 pubmed publisher
Muta Y, Fujita Y, Sumiyama K, Sakurai A, Taketo M, Chiba T, et al. Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine. Nat Commun. 2018;9:2174 pubmed publisher
Hill M, Alexander W, Guo B, Kato Y, Patra K, O Dell M, et al. Kras and Tp53 Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma. Cancer Res. 2018;78:4445-4451 pubmed publisher
Chen J, Zhou J, Gao Z, Li X, Wang F, Duan X, et al. Multiplexed Targeting of Barrett's Neoplasia with a Heterobivalent Ligand: Imaging Study on Mouse Xenograft in Vivo and Human Specimens ex Vivo. J Med Chem. 2018;61:5323-5331 pubmed publisher
Back M, Ha H, Fu Z, Choi J, Piao Y, Won J, et al. Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. Cell Death Dis. 2018;9:670 pubmed publisher
Lee J, Kim E, Kong H, Youm H, Kim S, Lee J, et al. Comparison of the Oocyte Quality Derived from Two-Dimensional Follicle Culture Methods and Developmental Competence of In Vitro Grown and Matured Oocytes. Biomed Res Int. 2018;2018:7907092 pubmed publisher
Tatavosian R, Duc H, Huynh T, Fang D, Schmitt B, Shi X, et al. Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation. Nat Commun. 2018;9:2080 pubmed publisher
Tomida J, Takata K, Bhetawal S, Person M, Chao H, Tang D, et al. FAM35A associates with REV7 and modulates DNA damage responses of normal and BRCA1-defective cells. EMBO J. 2018;37: pubmed publisher
Shindo A, Audrey A, Takagishi M, Takahashi M, Wallingford J, Kinoshita M. Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing. J Cell Sci. 2018;131: pubmed publisher
Agbani E, Williams C, Li Y, van den Bosch M, Moore S, Mauroux A, et al. Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis. JCI Insight. 2018;3: pubmed publisher
Muslimov I, Eom T, Iacoangeli A, Chuang S, Hukema R, Willemsen R, et al. BC RNA Mislocalization in the Fragile X Premutation. Eneuro. 2018;5: pubmed publisher
Bailey R, Armao D, Nagabhushan Kalburgi S, Gray S. Development of Intrathecal AAV9 Gene Therapy for Giant Axonal Neuropathy. Mol Ther Methods Clin Dev. 2018;9:160-171 pubmed publisher
Bunnik E, Cook K, Varoquaux N, Batugedara G, Prudhomme J, Cort A, et al. Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages. Nat Commun. 2018;9:1910 pubmed publisher
You J, Dooley M, Kim C, Kim E, Xu W, Goodman C, et al. A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling. Sci Signal. 2018;11: pubmed publisher
Alimonti J, Ribecco Lutkiewicz M, Sodja C, Jezierski A, Stanimirovic D, Liu Q, et al. Zika virus crosses an in vitro human blood brain barrier model. Fluids Barriers CNS. 2018;15:15 pubmed publisher
Voss J, Stermer A, Ghaffari R, Tiwary R, Richburg J. MEHP-induced rat testicular inflammation does not exacerbate germ cell apoptosis. Reproduction. 2018;156:35-46 pubmed publisher
Zur Lage P, Stefanopoulou P, Styczynska Soczka K, Quinn N, Mali G, von Kriegsheim A, et al. Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP. J Cell Biol. 2018;217:2583-2598 pubmed publisher
Hawkshaw N, Hardman J, Haslam I, Shahmalak A, Gilhar A, Lim X, et al. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles. PLoS Biol. 2018;16:e2003705 pubmed publisher
Luo F, Zhang J, Burke K, Romito Digiacomo R, Miller R, Yang Y. Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Exp Neurol. 2018;306:92-104 pubmed publisher
Pinarbasi E, Cagatay T, Fung H, Li Y, Chook Y, Thomas P. Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization. Sci Rep. 2018;8:7083 pubmed publisher
Aziz N, Guedj F, Pennings J, Olmos Serrano J, Siegel A, Haydar T, et al. Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome. Dis Model Mech. 2018;11: pubmed publisher
Toledo A, Grieger E, Karram K, Morrison H, Baader S. Neurofibromatosis type 2 tumor suppressor protein is expressed in oligodendrocytes and regulates cell proliferation and process formation. PLoS ONE. 2018;13:e0196726 pubmed publisher
Yuan X, Klein D, Kerscher S, West B, Weis J, Katona I, et al. Macrophage Depletion Ameliorates Peripheral Neuropathy in Aging Mice. J Neurosci. 2018;38:4610-4620 pubmed publisher
GALLOWAY A, Adeluyi A, O Donovan B, Fisher M, Rao C, Critchfield P, et al. Dopamine Triggers CTCF-Dependent Morphological and Genomic Remodeling of Astrocytes. J Neurosci. 2018;38:4846-4858 pubmed publisher
Kim H, Lee K, Kim S, Cho S, Shin H, Kim C, et al. Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection. Genome Res. 2018;28:859-868 pubmed publisher
Fernández Díez C, González Rojo S, Lombó M, Herráez M. Tolerance to paternal genotoxic damage promotes survival during embryo development in zebrafish (Danio rerio). Biol Open. 2018;7: pubmed publisher
Heukers R, Fan T, de Wit R, van Senten J, De Groof T, Bebelman M, et al. The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth. Oncogene. 2018;37:4110-4121 pubmed publisher
Lal P, Tanabe H, Suster M, Ailani D, Kotani Y, Muto A, et al. Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish. BMC Biol. 2018;16:45 pubmed publisher
Robins M, Chiang T, Mores K, Alongkronrusmee D, van Rijn R. Critical Role for Gi/o-Protein Activity in the Dorsal Striatum in the Reduction of Voluntary Alcohol Intake in C57Bl/6 Mice. Front Psychiatry. 2018;9:112 pubmed publisher
Anker J, Naseem A, Mok H, Schaeffer A, Abdulkadir S, Thumbikat P. Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy. Nat Commun. 2018;9:1591 pubmed publisher
Gouspillou G, Godin R, Piquereau J, Picard M, Mofarrahi M, Mathew J, et al. Protective role of Parkin in skeletal muscle contractile and mitochondrial function. J Physiol. 2018;596:2565-2579 pubmed publisher
Jia J, Conlon T, Sarker R, Taşdemir D, Smirnova N, Srivastava B, et al. Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease. EMBO Mol Med. 2018;10: pubmed publisher
Wang X, Bi X, Zhang G, Deng Y, Luo X, Xu L, et al. Glucose-regulated protein 78 is essential for cardiac myocyte survival. Cell Death Differ. 2018;25:2181-2194 pubmed publisher
Fu X, Khalil H, Kanisicak O, Boyer J, Vagnozzi R, Maliken B, et al. Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart. J Clin Invest. 2018;128:2127-2143 pubmed publisher
Beeharry Y, Goodrum G, Imperiale C, Pelchat M. The Hepatitis Delta Virus accumulation requires paraspeckle components and affects NEAT1 level and PSP1 localization. Sci Rep. 2018;8:6031 pubmed publisher
Itsara L, Zhou Y, Do J, Dungel S, Fishbaugher M, Betz W, et al. PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro. Malar J. 2018;17:135 pubmed publisher
Li P, Feng C, Chen H, Jiang Y, Cao F, Liu J, et al. Elevated CRB3 expression suppresses breast cancer stemness by inhibiting ?-catenin signalling to restore tamoxifen sensitivity. J Cell Mol Med. 2018;22:3423-3433 pubmed publisher
Bai L, Lee Y, Hsu C, Williams J, Cavanaugh D, Zheng X, et al. A Conserved Circadian Function for the Neurofibromatosis 1 Gene. Cell Rep. 2018;22:3416-3426 pubmed publisher
Haahr P, Borgermann N, Guo X, Typas D, Achuthankutty D, Hoffmann S, et al. ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability. Mol Cell. 2018;70:165-174.e6 pubmed publisher
Hsu P, Miao J, Huang Z, Yang Y, Xu Z, You J, et al. Inhibition of yes-associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model. J Cell Mol Med. 2018;22:3073-3085 pubmed publisher
Gong Z, Zhou Q. Dnmt3a in the dorsal dentate gyrus is a key regulator of fear renewal. Sci Rep. 2018;8:5093 pubmed publisher
Kim H, Koo Y, Shin M, Kim S, Shin Y, Choi B, et al. Combination of Constraint-Induced Movement Therapy with Electroacupuncture Improves Functional Recovery following Neonatal Hypoxic-Ischemic Brain Injury in Rats. Biomed Res Int. 2018;2018:8638294 pubmed publisher
Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, et al. Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3. J Lipid Res. 2018;59:805-819 pubmed publisher
Lee J, Shanina I, Chu Y, Horwitz M, Johnson J. Carbamazepine, a beta-cell protecting drug, reduces type 1 diabetes incidence in NOD mice. Sci Rep. 2018;8:4588 pubmed publisher
Bonfim Melo A, Ferreira d, Mortara R. Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi. Front Microbiol. 2018;9:360 pubmed publisher
Kuwahara H, Song J, Shimoura T, Yoshida Tanaka K, Mizuno T, Mochizuki T, et al. Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Sci Rep. 2018;8:4377 pubmed publisher
Hill P, Leitch H, Requena C, Sun Z, Amouroux R, Román Trufero M, et al. Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte. Nature. 2018;555:392-396 pubmed publisher
Lyukmanova E, Bychkov M, Sharonov G, Efremenko A, Shulepko M, Kulbatskii D, et al. Human secreted proteins SLURP-1 and SLURP-2 control the growth of epithelial cancer cells via interactions with nicotinic acetylcholine receptors. Br J Pharmacol. 2018;175:1973-1986 pubmed publisher
Fraschka S, Filarsky M, Hoo R, Niederwieser I, Yam X, Brancucci N, et al. Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites. Cell Host Microbe. 2018;23:407-420.e8 pubmed publisher
Mitok K, Freiberger E, Schueler K, Rabaglia M, Stapleton D, Kwiecien N, et al. Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion. J Biol Chem. 2018;293:5860-5877 pubmed publisher
Liu W, Molnár M, Garnham C, Benav H, Rask Andersen H. Macrophages in the Human Cochlea: Saviors or Predators-A Study Using Super-Resolution Immunohistochemistry. Front Immunol. 2018;9:223 pubmed publisher
Wu Y, Feng D, Lin J, Qu Y, He S, Wang Y, et al. Downregulation of G‑protein‑coupled receptor 30 in the hippocampus attenuates the neuroprotection of estrogen in the critical period hypothesis. Mol Med Rep. 2018;17:5716-5725 pubmed publisher
Tremblay C, Huang F, Levesque G, Carreau M. Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity. BMC Res Notes. 2018;11:138 pubmed publisher
Singh N, Kansal P, Ahmad Z, Baid N, Kushwaha H, Khatri N, et al. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis. Autophagy. 2018;14:972-991 pubmed publisher
Gao X, Yuan Y, Lin Q, Xu J, Wang W, Qiao Y, et al. Mutation of IFNLR1, an interferon lambda receptor 1, is associated with autosomal-dominant non-syndromic hearing loss. J Med Genet. 2018;55:298-306 pubmed publisher
Yurchenko M, Skjesol A, Ryan L, Richard G, Kandasamy R, Wang N, et al. SLAMF1 is required for TLR4-mediated TRAM-TRIF-dependent signaling in human macrophages. J Cell Biol. 2018;217:1411-1429 pubmed publisher
Das S, Yuan Y, Li M. Specific PKC βII inhibitor: one stone two birds in the treatment of diabetic foot ulcers. Biosci Rep. 2018;38: pubmed publisher
Zhou Z, Li M, Zhang L, Zhao H, Sahin O, Chen J, et al. Oncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells. Cancer Res. 2018;78:2248-2261 pubmed publisher
Pfuhlmann K, Schriever S, Legutko B, Baumann P, Harrison L, Kabra D, et al. Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice. J Neuroinflammation. 2018;15:35 pubmed publisher
Gustafson C, Mamo T, Maran A, Yaszemski M. Efflux inhibition by IWR-1-endo confers sensitivity to doxorubicin effects in osteosarcoma cells. Biochem Pharmacol. 2018;150:141-149 pubmed publisher
Ladanyi A, Mukherjee A, Kenny H, Johnson A, Mitra A, Sundaresan S, et al. Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis. Oncogene. 2018;37:2285-2301 pubmed publisher
Rosengren T, Larsen L, Pedersen L, Christensen S, Møller L. TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms. Cell Mol Life Sci. 2018;75:2663-2680 pubmed publisher
Stoll L, Sobel J, Rodríguez Trejo A, Guay C, Lee K, Venø M, et al. Circular RNAs as novel regulators of β-cell functions in normal and disease conditions. Mol Metab. 2018;9:69-83 pubmed publisher
Youn J, Dunham W, Hong S, Knight J, Bashkurov M, Chen G, et al. High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Mol Cell. 2018;69:517-532.e11 pubmed publisher
Chen B, Liu G. WWC3 inhibits intimal proliferation following vascular injury via the Hippo signaling pathway. Mol Med Rep. 2018;17:5175-5183 pubmed publisher
Weber F, Hoang Do J, Chung S, BEIER K, Bikov M, Saffari Doost M, et al. Regulation of REM and Non-REM Sleep by Periaqueductal GABAergic Neurons. Nat Commun. 2018;9:354 pubmed publisher
Yuan J, Liu Y, Wang J, Zhao Y, Li K, Jing Y, et al. Long-term Persistent Organic Pollutants Exposure Induced Telomere Dysfunction and Senescence-Associated Secretary Phenotype. J Gerontol A Biol Sci Med Sci. 2018;73:1027-1035 pubmed publisher
McCarthy C, Wenceslau C, Ogbi S, Szasz T, Webb R. Toll-Like Receptor 9-Dependent AMPKα Activation Occurs via TAK1 and Contributes to RhoA/ROCK Signaling and Actin Polymerization in Vascular Smooth Muscle Cells. J Pharmacol Exp Ther. 2018;365:60-71 pubmed publisher
Lloyd Lewis B, Krueger C, Sargeant T, D Angelo M, Deery M, Feret R, et al. Stat3-mediated alterations in lysosomal membrane protein composition. J Biol Chem. 2018;293:4244-4261 pubmed publisher
Aktas Z, Rao H, Slauson S, Gabelt B, Larsen I, Sheridan R, et al. Proteasome Inhibition Increases the Efficiency of Lentiviral Vector-Mediated Transduction of Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2018;59:298-310 pubmed publisher
Li X, Zhang Y, Jin Q, Xia K, Jiang M, Cui B, et al. Liver kinase B1/AMP-activated protein kinase-mediated regulation by gentiopicroside ameliorates P2X7 receptor-dependent alcoholic hepatosteatosis. Br J Pharmacol. 2018;175:1451-1470 pubmed publisher
Schnaitmann C, Haikala V, Abraham E, Oberhauser V, Thestrup T, Griesbeck O, et al. Color Processing in the Early Visual System of Drosophila. Cell. 2018;172:318-330.e18 pubmed publisher
Jean P, Lopez de la Morena D, Michanski S, Jaime Tobón L, Chakrabarti R, Picher M, et al. The synaptic ribbon is critical for sound encoding at high rates and with temporal precision. elife. 2018;7: pubmed publisher
Workman A, Zhu L, Keel B, Smith T, Jones C. The Wnt Signaling Pathway Is Differentially Expressed during the Bovine Herpesvirus 1 Latency-Reactivation Cycle: Evidence That Two Protein Kinases Associated with Neuronal Survival, Akt3 and BMPR2, Are Expressed at Higher Levels during Latency. J Virol. 2018;92: pubmed publisher
Fellows R, Denizot J, Stellato C, Cuomo A, Jain P, Stoyanova E, et al. Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases. Nat Commun. 2018;9:105 pubmed publisher
Iwasaki Y, Sendo M, Dezaki K, Hira T, Sato T, Nakata M, et al. GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose. Nat Commun. 2018;9:113 pubmed publisher
De Angelis M, Parrotta E, Santamaria G, Cuda G. Short-term retinoic acid treatment sustains pluripotency and suppresses differentiation of human induced pluripotent stem cells. Cell Death Dis. 2018;9:6 pubmed publisher
Kim H, McKnite A, Xie Y, Christian J. Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling. Mol Biol Cell. 2018;29:523-531 pubmed publisher
Milanovic M, Fan D, Belenki D, Däbritz J, Zhao Z, Yu Y, et al. Senescence-associated reprogramming promotes cancer stemness. Nature. 2018;553:96-100 pubmed publisher
Jeschke A, Haas A. Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion. Mol Biol Cell. 2018;29:452-465 pubmed publisher
Cieri D, Vicario M, Giacomello M, Vallese F, Filadi R, Wagner T, et al. SPLICS: a split green fluorescent protein-based contact site sensor for narrow and wide heterotypic organelle juxtaposition. Cell Death Differ. 2018;25:1131-1145 pubmed publisher
Yen J, Wei L, Chen L, Chen L, Hung C, Wang S, et al. Subcellular Localization and Functional Characterization of GII.4 Norovirus-Encoded NTPase. J Virol. 2018;92: pubmed publisher
Yamamura H, Nishimura K, Hagihara Y, Suzuki Y, Imaizumi Y. TMEM16A and TMEM16B channel proteins generate Ca2+-activated Cl- current and regulate melatonin secretion in rat pineal glands. J Biol Chem. 2018;293:995-1006 pubmed publisher
Cox N, Unlu G, Bisnett B, Meister T, Condon B, Luo P, et al. Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway. Biochemistry. 2018;57:91-107 pubmed publisher
Romano V, Parekh M, Ruzza A, Willoughby C, Ferrari S, Ponzin D, et al. Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty. Br J Ophthalmol. 2018;102:549-555 pubmed publisher
Arcego D, Toniazzo A, Krolow R, Lampert C, Berlitz C, Dos Santos Garcia E, et al. Impact of High-Fat Diet and Early Stress on Depressive-Like Behavior and Hippocampal Plasticity in Adult Male Rats. Mol Neurobiol. 2018;55:2740-2753 pubmed publisher
Jeong W, Bae H, Lim W, Bazer F, Lee H, Song G. The functional effects and mechanisms by which fibroblast growth factor 2 (FGF2) controls bovine mammary epithelial cells: Implications for the development and functionality of the bovine mammary gland. J Anim Sci. 2017;95:5365-5377 pubmed publisher
Jeong W, Bae H, Lim W, Bazer F, Song G. Adiponectin: A prosurvival and proproliferation signal that increases bovine mammary epithelial cell numbers and protects them from endoplasmic reticulum stress responses. J Anim Sci. 2017;95:5278-5289 pubmed publisher
Guo W, Liu W, Chen Z, Gu Y, Peng S, Shen L, et al. Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis. Nat Commun. 2017;8:2168 pubmed publisher
Tucker N, McLellan M, Hu D, Ye J, Parsons V, Mills R, et al. Novel Mutation in FLNC (Filamin C) Causes Familial Restrictive Cardiomyopathy. Circ Cardiovasc Genet. 2017;10: pubmed publisher
Arakaki Y, Fujiwara T, Kawai Toyooka H, Kawafune K, Featherston J, Durand P, et al. Evolution of cytokinesis-related protein localization during the emergence of multicellularity in volvocine green algae. BMC Evol Biol. 2017;17:243 pubmed publisher
Scherer P, Zaccor N, Neumann N, Vasavda C, Barrow R, Ewald A, et al. TRPV1 is a physiological regulator of μ-opioid receptors. Proc Natl Acad Sci U S A. 2017;114:13561-13566 pubmed publisher
Leonel L, Miranda C, Coelho T, Ferreira G, Caãada R, Miglino M, et al. Decellularization of placentas: establishing a protocol. Braz J Med Biol Res. 2017;51:e6382 pubmed publisher
Nallasamy S, Akins M, Tetreault B, Luby Phelps K, Mahendroo M. Distinct reorganization of collagen architecture in lipopolysaccharide - mediated premature cervical remodeling. Biol Reprod. 2017;: pubmed publisher
Tamura N, Nishimura T, Sakamaki Y, Koyama Honda I, Yamamoto H, Mizushima N. Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets. FEBS Lett. 2017;591:3819-3830 pubmed publisher
Dicks N, Bohrer R, Gutierrez K, Michalak M, Agellon L, Bordignon V. Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos. PLoS ONE. 2017;12:e0187717 pubmed publisher
Murao N, Yokoi N, Honda K, Han G, Hayami T, Gheni G, et al. Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion. PLoS ONE. 2017;12:e0187213 pubmed publisher
Nakamuta S, Yang Y, Wang C, Gallo N, Yu J, Tai Y, et al. Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. J Cell Biol. 2017;216:4313-4330 pubmed publisher
Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, et al. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. Proc Natl Acad Sci U S A. 2017;114:E9579-E9588 pubmed publisher
Voisin M, de Medina P, Mallinger A, Dalenc F, Huc Claustre E, Leignadier J, et al. Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor. Proc Natl Acad Sci U S A. 2017;114:E9346-E9355 pubmed publisher
Liang C, Kerr A, Qiu Y, Cristofoli F, Van Esch H, Fox M, et al. Optic Nerve Hypoplasia Is a Pervasive Subcortical Pathology of Visual System in Neonates. Invest Ophthalmol Vis Sci. 2017;58:5485-5496 pubmed publisher
Hos N, Ganesan R, Gutierrez S, Hos D, Klimek J, Abdullah Z, et al. Type I interferon enhances necroptosis of Salmonella Typhimurium-infected macrophages by impairing antioxidative stress responses. J Cell Biol. 2017;216:4107-4121 pubmed publisher
Gibson B, Conrad L, Huang D, Kraus W. Generation and Characterization of Recombinant Antibody-like ADP-Ribose Binding Proteins. Biochemistry. 2017;: pubmed publisher
Verma M, Callio J, Otero P, Sekler I, Wills Z, Chu C. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants. J Neurosci. 2017;37:11151-11165 pubmed publisher
Moriel Carretero M, Ovejero S, Gérus Durand M, Vryzas D, Constantinou A. Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors. J Cell Biol. 2017;216:4007-4026 pubmed publisher
Thévenin A, Margraf R, Fisher C, Kells Andrews R, Falk M. Phosphorylation regulates connexin43/ZO-1 binding and release, an important step in gap junction turnover. Mol Biol Cell. 2017;28:3595-3608 pubmed publisher
Yuan H, Deng R, Zhao X, Chen R, Hou G, Zhang H, et al. SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis. Mol Cancer. 2017;16:157 pubmed publisher
Filipek P, de Araujo M, Vogel G, De Smet C, Eberharter D, Rebsamen M, et al. LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning. J Cell Biol. 2017;216:4199-4215 pubmed publisher
Qian Y, Cao Y, Deng B, Yang G, Li J, Xu R, et al. Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila. elife. 2017;6: pubmed publisher
Zhou H, Morales M, Hashimoto H, Dickson M, Song K, Ye W, et al. ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression. Genes Dev. 2017;31:1770-1783 pubmed publisher
Ghosh E, Srivastava A, Baidya M, Kumari P, Dwivedi H, Nidhi K, et al. A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis. Nat Nanotechnol. 2017;12:1190-1198 pubmed publisher
Camell C, Sander J, Spadaro O, Lee A, Nguyen K, Wing A, et al. Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. Nature. 2017;550:119-123 pubmed publisher
Kurzhals R, Fanti L, Ebsen A, Rong Y, Pimpinelli S, Golic K. Chromosome Healing Is Promoted by the Telomere Cap Component Hiphop in Drosophila. Genetics. 2017;207:949-959 pubmed publisher
Reithmeier A, Panizza E, Krumpel M, Orre L, Branca R, Lehtiö J, et al. Tartrate-resistant acid phosphatase (TRAP/ACP5) promotes metastasis-related properties via TGF?2/T?R and CD44 in MDA-MB-231 breast cancer cells. BMC Cancer. 2017;17:650 pubmed publisher
Poillet Perez L, Jacquet M, Hervouet E, Gauthier T, Fraichard A, Borg C, et al. GABARAPL1 tumor suppressive function is independent of its conjugation to autophagosomes in MCF-7 breast cancer cells. Oncotarget. 2017;8:55998-56020 pubmed publisher
Menzel S, Finocchiaro N, Donay C, Thiebes A, Hesselmann F, Arens J, et al. Towards a Biohybrid Lung: Endothelial Cells Promote Oxygen Transfer through Gas Permeable Membranes. Biomed Res Int. 2017;2017:5258196 pubmed publisher
Böttcher R, Veelders M, Rombaut P, Faix J, Theodosiou M, Stradal T, et al. Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. J Cell Biol. 2017;216:3785-3798 pubmed publisher
Moruno Manchon J, Koellhoffer E, Gopakumar J, Hambarde S, Kim N, McCullough L, et al. The G-quadruplex DNA stabilizing drug pyridostatin promotes DNA damage and downregulates transcription of Brca1 in neurons. Aging (Albany NY). 2017;9:1957-1970 pubmed publisher
Okumura M, Wilecki M, Sommer R. Serotonin Drives Predatory Feeding Behavior via Synchronous Feeding Rhythms in the Nematode Pristionchus pacificus. G3 (Bethesda). 2017;7:3745-3755 pubmed publisher
Lee S, Han S, Kim M, Shim S, Shin H, Lee S, et al. Post-irradiation promotes susceptibility to reprogramming to pluripotent state in human fibroblasts. Cell Cycle. 2017;16:2119-2127 pubmed publisher
Sasaki T, Sato Y, Higashiyama T, Sasaki N. Live imaging reveals the dynamics and regulation of mitochondrial nucleoids during the cell cycle in Fucci2-HeLa cells. Sci Rep. 2017;7:11257 pubmed publisher
Cuellar T, Herzner A, Zhang X, Goyal Y, Watanabe C, Friedman B, et al. Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia. J Cell Biol. 2017;216:3535-3549 pubmed publisher
Li C, Götz J. Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation. EMBO J. 2017;36:3120-3138 pubmed publisher
Watanabe K, Chiu H, Pfeiffer B, Wong A, Hoopfer E, Rubin G, et al. A Circuit Node that Integrates Convergent Input from Neuromodulatory and Social Behavior-Promoting Neurons to Control Aggression in Drosophila. Neuron. 2017;95:1112-1128.e7 pubmed publisher
Lu J, Hsieh M, Hou H, Chen C, Tien H, Lin L. Overexpression of SOX4 correlates with poor prognosis of acute myeloid leukemia and is leukemogenic in zebrafish. Blood Cancer J. 2017;7:e593 pubmed publisher
Macchiarulo S, Morrow B. Tbx1 and Jag1 act in concert to modulate the fate of neurosensory cells of the mouse otic vesicle. Biol Open. 2017;6:1472-1482 pubmed publisher
Scott M, Kammermeier P. CaV2 channel subtype expression in rat sympathetic neurons is selectively regulated by ?2? subunits. Channels (Austin). 2017;11:555-573 pubmed publisher
Leroy F, Brann D, Meira T, Siegelbaum S. Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory. Neuron. 2017;95:1089-1102.e5 pubmed publisher
Chen Y, Wang D, Wu Y, Su D, Zhou T, Gai R, et al. MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. Br J Cancer. 2017;117:1192-1201 pubmed publisher
Tran L, Kichenadasse G, Butler L, Centenera M, Morel K, Ormsby R, et al. The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer. Mol Cancer Ther. 2017;16:2689-2700 pubmed publisher
Luo W, Tan P, Rodriguez M, He L, Tan K, Zeng L, et al. Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition. J Biol Chem. 2017;292:15525-15537 pubmed publisher
Cahoon C, Yu Z, Wang Y, Guo F, Unruh J, Slaughter B, et al. Superresolution expansion microscopy reveals the three-dimensional organization of the Drosophila synaptonemal complex. Proc Natl Acad Sci U S A. 2017;114:E6857-E6866 pubmed publisher
Guo R, Tang W, Yuan Q, Hui L, Wang X, Xie X. Chemical Cocktails Enable Hepatic Reprogramming of Mouse Fibroblasts with a Single Transcription Factor. Stem Cell Reports. 2017;9:499-512 pubmed publisher
Kenyon A, Gavriouchkina D, Zorman J, Napolitani G, Cerundolo V, Sauka Spengler T. Active nuclear transcriptome analysis reveals inflammasome-dependent mechanism for early neutrophil response to Mycobacterium marinum. Sci Rep. 2017;7:6505 pubmed publisher
Jin M, Fuller G, Han T, Yao Y, Alessi A, Freeberg M, et al. Glycolytic Enzymes Coalesce in G Bodies under Hypoxic Stress. Cell Rep. 2017;20:895-908 pubmed publisher
Mackenzie K, Carroll P, Martin C, Murina O, Fluteau A, Simpson D, et al. cGAS surveillance of micronuclei links genome instability to innate immunity. Nature. 2017;548:461-465 pubmed publisher
Webber M, Thomson J, Buckland Nicks J, Croll R, Wyeth R. GABA-, histamine-, and FMRFamide-immunoreactivity in the visual, vestibular and central nervous systems of Hermissenda crassicornis. J Comp Neurol. 2017;525:3514-3528 pubmed publisher
Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, et al. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLoS Genet. 2017;13:e1006892 pubmed publisher
Stefansson O, Hermanowicz S, van der Horst J, Hilmarsdottir H, Staszczak Z, Jonasson J, et al. CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer. BMC Cancer. 2017;17:469 pubmed publisher
Paolicelli R, Jawaid A, Henstridge C, Valeri A, Merlini M, Robinson J, et al. TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss. Neuron. 2017;95:297-308.e6 pubmed publisher
Li X, Yao B, Chen L, Kang Y, Li Y, Cheng Y, et al. Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis. Nat Commun. 2017;8:15903 pubmed publisher
Laviolette L, Mermoud J, Calvo I, Olson N, Boukhali M, Steinlein O, et al. Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein. Nat Commun. 2017;8:15866 pubmed publisher
Smith T, Li J, Dores M, Trejo J. Protease-activated receptor-4 and purinergic receptor P2Y12 dimerize, co-internalize, and activate Akt signaling via endosomal recruitment of β-arrestin. J Biol Chem. 2017;292:13867-13878 pubmed publisher
Clark A, Nogales A, Martinez Sobrido L, Topham D, DeDiego M. Functional Evolution of Influenza Virus NS1 Protein in Currently Circulating Human 2009 Pandemic H1N1 Viruses. J Virol. 2017;91: pubmed publisher
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, et al. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017;546:549-553 pubmed publisher
Shen M, Jiang Y, Guan Z, Cao Y, Li L, Liu H, et al. Protective mechanism of FSH against oxidative damage in mouse ovarian granulosa cells by repressing autophagy. Autophagy. 2017;13:1364-1385 pubmed publisher
Han C, Zeng X, Yao S, Gao L, Zhang L, Qi X, et al. Voltage-Dependent Anion Channel 1 Interacts with Ribonucleoprotein Complexes To Enhance Infectious Bursal Disease Virus Polymerase Activity. J Virol. 2017;91: pubmed publisher
Shahi P, Wang C, Chou J, Hagerling C, Gonzalez Velozo H, Ruderisch A, et al. GATA3 targets semaphorin 3B in mammary epithelial cells to suppress breast cancer progression and metastasis. Oncogene. 2017;36:5567-5575 pubmed publisher
Grossman N, Bono D, Dedic N, Kodandaramaiah S, Rudenko A, Suk H, et al. Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields. Cell. 2017;169:1029-1041.e16 pubmed publisher
Bourgeois C, Satou R, Prieto M. HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference. Biol Sex Differ. 2017;8:18 pubmed publisher
Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed publisher
Sullivan S, Farrant M, Cull Candy S. TARP ?-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn. J Neurosci. 2017;37:6007-6020 pubmed publisher
Wang L, Yu C, Wang J, Leung P, Ma D, Zhao H, et al. Nogo-B is the major form of Nogo at the floor plate and likely mediates crossing of commissural axons in the mouse spinal cord. J Comp Neurol. 2017;525:2915-2928 pubmed publisher
Antfolk D, Sjöqvist M, Cheng F, Isoniemi K, Duran C, Rivero Muller A, et al. Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proc Natl Acad Sci U S A. 2017;114:E4574-E4581 pubmed publisher
Paci P, Gabriele S, Ris L. A new method allowing long-term potentiation recordings in hippocampal organotypic slices. Brain Behav. 2017;7:e00692 pubmed publisher
Eskova A, Chauvigné F, Maischein H, Ammelburg M, Cerdà J, NUSSLEIN VOLHARD C, et al. Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment. Development. 2017;144:2059-2069 pubmed publisher
Pappas K, Xu J, Zairis S, Resnick Silverman L, Abate F, Steinbach N, et al. p53 Maintains Baseline Expression of Multiple Tumor Suppressor Genes. Mol Cancer Res. 2017;15:1051-1062 pubmed publisher
Solek C, Feng S, Perin S, Weinschutz Mendes H, Ekker M. Lineage tracing of dlx1a/2a and dlx5a/6a expressing cells in the developing zebrafish brain. Dev Biol. 2017;427:131-147 pubmed publisher
Chu D, Gromova T, Newman T, Burgess S. The Nucleoporin Nup2 Contains a Meiotic-Autonomous Region that Promotes the Dynamic Chromosome Events of Meiosis. Genetics. 2017;206:1319-1337 pubmed publisher
Kim H, Lee K, Bae S, Park J, Lee C, Kim M, et al. CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection. J Biol Chem. 2017;292:10664-10671 pubmed publisher
Wang S, Ehrlich D. Image-Based Phenotypic Screening with Human Primary T Cells Using One-Dimensional Imaging Cytometry with Self-Tuning Statistical-Gating Algorithms. SLAS Discov. 2017;22:985-994 pubmed publisher
Riemer P, Rydenfelt M, Marks M, van Eunen K, Thedieck K, Herrmann B, et al. Oncogenic β-catenin and PIK3CA instruct network states and cancer phenotypes in intestinal organoids. J Cell Biol. 2017;216:1567-1577 pubmed publisher
Bastos R, Howard Z, Hiroyasu A, Goodman A. Host and Bacterial Factors Control Susceptibility of Drosophila melanogaster to Coxiella burnetii Infection. Infect Immun. 2017;85: pubmed publisher
Severson K, Xu D, Van de Loo M, Bai L, Ginty D, O Connor D. Active Touch and Self-Motion Encoding by Merkel Cell-Associated Afferents. Neuron. 2017;94:666-676.e9 pubmed publisher
Fu H, Zhang T, Huang R, Yang Z, Liu C, Li M, et al. Calcitonin gene-related peptide protects type II alveolar epithelial cells from hyperoxia-induced DNA damage and cell death. Exp Ther Med. 2017;13:1279-1284 pubmed publisher
Bhujabal Z, Birgisdottir A, Sjøttem E, Brenne H, Øvervatn A, Habisov S, et al. FKBP8 recruits LC3A to mediate Parkin-independent mitophagy. EMBO Rep. 2017;18:947-961 pubmed publisher
Hanssen A, Kindlund B, Stenklev N, Furberg A, Fismen S, Olsen R, et al. Localization of Staphylococcus aureus in tissue from the nasal vestibule in healthy carriers. BMC Microbiol. 2017;17:89 pubmed publisher
Perrott K, Wiley C, Desprez P, Campisi J. Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells. GeroScience. 2017;39:161-173 pubmed publisher
Yang S, Pei Y, Zhao A. iTRAQ-based Proteomic Analysis of Porcine Kidney Epithelial PK15 cells Infected with Pseudorabies virus. Sci Rep. 2017;7:45922 pubmed publisher
He L, Luo L, Zhu H, Yang H, Zhang Y, Wu H, et al. FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer. Mol Oncol. 2017;11:640-654 pubmed publisher
Bouhours B, Gjoni E, Kochubey O, Schneggenburger R. Synaptotagmin2 (Syt2) Drives Fast Release Redundantly with Syt1 at the Output Synapses of Parvalbumin-Expressing Inhibitory Neurons. J Neurosci. 2017;37:4604-4617 pubmed publisher
Okazaki A, Gameiro P, Christodoulou D, Laviollette L, Schneider M, Chaves F, et al. Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers. J Clin Invest. 2017;127:1631-1645 pubmed publisher
Dong E, Bachleda A, Xiong Y, Osawa S, Weiss E. Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice. Mol Vis. 2017;23:90-102 pubmed
Leung J, He Y, Zhang F, Hwang Y, Nagayasu E, Liu J, et al. Stability and function of a putative microtubule-organizing center in the human parasite Toxoplasma gondii. Mol Biol Cell. 2017;28:1361-1378 pubmed publisher
Sarper M, Allen M, Gomm J, Haywood L, Decock J, Thirkettle S, et al. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res. 2017;19:33 pubmed publisher
Chauvigné F, Ollé J, Gonzalez W, Duncan N, Gimenez I, Cerdà J. Toward developing recombinant gonadotropin-based hormone therapies for increasing fertility in the flatfish Senegalese sole. PLoS ONE. 2017;12:e0174387 pubmed publisher
Thomas J, Eric Dollins D, Andrykovich K, Chu T, Stultz B, Hursh D, et al. SMOC can act as both an antagonist and an expander of BMP signaling. elife. 2017;6: pubmed publisher
Padró M, Louie R, Lananna B, Krieg A, Timmerman L, Chan D. Genome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells. BMC Cancer. 2017;17:203 pubmed publisher
Yudasaka M, Yomogida Y, Zhang M, Tanaka T, Nakahara M, Kobayashi N, et al. Near-Infrared Photoluminescent Carbon Nanotubes for Imaging of Brown Fat. Sci Rep. 2017;7:44760 pubmed publisher
Cheng X, Ma X, Ding X, Li L, Jiang X, Shen Z, et al. Pacer Mediates the Function of Class III PI3K and HOPS Complexes in Autophagosome Maturation by Engaging Stx17. Mol Cell. 2017;65:1029-1043.e5 pubmed publisher
Mamo T, Mladek A, Shogren K, Gustafson C, Gupta S, Riester S, et al. Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells. Biochem Biophys Res Commun. 2017;486:307-313 pubmed publisher
Hodson C, Hamilton P, Dilworth D, Nelson C, Curtis C, Perlman S. Paternal Genome Elimination in Liposcelis Booklice (Insecta: Psocodea). Genetics. 2017;206:1091-1100 pubmed publisher
Halim D, Wilson M, Oliver D, Brosens E, Verheij J, Han Y, et al. Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice. Proc Natl Acad Sci U S A. 2017;114:E2739-E2747 pubmed publisher
Pievani A, Sacchetti B, Corsi A, Rambaldi B, Donsante S, Scagliotti V, et al. Human umbilical cord blood-borne fibroblasts contain marrow niche precursors that form a bone/marrow organoid in vivo. Development. 2017;144:1035-1044 pubmed publisher
Briz C, Navarrete M, Esteban J, Nieto M. In Utero Electroporation Approaches to Study the Excitability of Neuronal Subpopulations and Single-cell Connectivity. J Vis Exp. 2017;: pubmed publisher
Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed publisher
Brancaccio M, Patton A, Chesham J, Maywood E, Hastings M. Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling. Neuron. 2017;93:1420-1435.e5 pubmed publisher
Kim J, Choi S, Kwack K, Kim S, Lee H, Park K. G protein-coupled calcium-sensing receptor is a crucial mediator of MTA-induced biological activities. Biomaterials. 2017;127:107-116 pubmed publisher
Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed publisher
Trussart M, Yus E, Martínez S, Baù D, Tahara Y, Pengo T, et al. Defined chromosome structure in the genome-reduced bacterium Mycoplasma pneumoniae. Nat Commun. 2017;8:14665 pubmed publisher
Jeong J, Lee D, Jo Y. Cholinergic neurons in the dorsomedial hypothalamus regulate food intake. Mol Metab. 2017;6:306-312 pubmed publisher
He W, Wang X, Shi H, Bai W, Cheng B, Su Y, et al. Cutaneous neurogenic inflammation in the sensitized acupoints induced by gastric mucosal injury in rats. BMC Complement Altern Med. 2017;17:141 pubmed publisher
Tekari A, May R, Frauchiger D, Chan S, Benneker L, Gantenbein B. The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells. Eur Cell Mater. 2017;33:197-210 pubmed publisher
Park S, Choi Y, Jung N, Kim J, Oh S, Yu Y, et al. Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells. Int J Mol Med. 2017;39:831-840 pubmed publisher
Truong A, Hong Y, Hoang C, Lee J, Hong Y. Chicken IL-26 regulates immune responses through the JAK/STAT and NF-κB signaling pathways. Dev Comp Immunol. 2017;73:10-20 pubmed publisher
Han X, Li P, Yang Z, Huang X, Wei G, Sun Y, et al. Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules. Nat Commun. 2017;8:14639 pubmed publisher
Song Y, Jang J, Shin T, Bae S, Kim J, Kim K, et al. Sulfasalazine attenuates evading anticancer response of CD133-positive hepatocellular carcinoma cells. J Exp Clin Cancer Res. 2017;36:38 pubmed publisher
Mishra V, Subramaniam M, Kari V, Pitel K, Baumgart S, Naylor R, et al. Krüppel-like Transcription Factor KLF10 Suppresses TGFβ-Induced Epithelial-to-Mesenchymal Transition via a Negative Feedback Mechanism. Cancer Res. 2017;77:2387-2400 pubmed publisher
Caberlotto E, Ruiz L, Miller Z, Poletti M, Tadlock L. Effects of a skin-massaging device on the ex-vivo expression of human dermis proteins and in-vivo facial wrinkles. PLoS ONE. 2017;12:e0172624 pubmed publisher
Scekic Zahirovic J, Oussini H, Mersmann S, Drenner K, Wagner M, Sun Y, et al. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. Acta Neuropathol. 2017;133:887-906 pubmed publisher
Brown D, Filiz G, Daniel P, Hollande F, Dworkin S, Amiridis S, et al. Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity. PLoS ONE. 2017;12:e0172791 pubmed publisher
Sun S, Xu Q, Guo C, Guan Y, Liu Q, Dong X. Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord. Neuron. 2017;93:840-853.e5 pubmed publisher
Morrow R, Picard M, Derbeneva O, Leipzig J, McManus M, Gouspillou G, et al. Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity. Proc Natl Acad Sci U S A. 2017;114:2705-2710 pubmed publisher
Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher
Saarela U, Akram S, Desgrange A, Rak Raszewska A, Shan J, Cereghini S, et al. Novel fixed z-direction (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging. Development. 2017;144:1113-1117 pubmed publisher
Prasad S, Sajja R, Kaisar M, Park J, Villalba H, Liles T, et al. Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity. Redox Biol. 2017;12:58-69 pubmed publisher
Higaki S, Shimada M, Kawamoto K, Todo T, Kawasaki T, Tooyama I, et al. In vitro differentiation of fertile sperm from cryopreserved spermatogonia of the endangered endemic cyprinid honmoroko (Gnathopogon caerulescens). Sci Rep. 2017;7:42852 pubmed publisher
Gao S, Li C, Zhu Y, Wang Y, Sui A, Zhong Y, et al. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy. Sci Rep. 2017;7:42846 pubmed publisher
Kovacs T, Billes V, Komlos M, Hotzi B, Manzéger A, Tarnóci A, et al. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci Rep. 2017;7:42014 pubmed publisher
Subashini C, Dhanesh S, Chen C, Riya P, Meera V, Divya T, et al. Wnt5a is a crucial regulator of neurogenesis during cerebellum development. Sci Rep. 2017;7:42523 pubmed publisher
Erdogan B, Cammarata G, Lee E, Pratt B, Francl A, Rutherford E, et al. The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development. Neural Dev. 2017;12:3 pubmed publisher
Fremont R, Tewari A, Angueyra C, Khodakhah K. A role for cerebellum in the hereditary dystonia DYT1. elife. 2017;6: pubmed publisher
Herrfurth L, Theis V, Matschke V, May C, Marcus K, Theiss C. Morphological Plasticity of Emerging Purkinje Cells in Response to Exogenous VEGF. Front Mol Neurosci. 2017;10:2 pubmed publisher
Tao L, Xiang D, Xie Y, Bronson R, Li Z. Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours. Nat Commun. 2017;8:14431 pubmed publisher
Ripa R, Dolfi L, Terrigno M, Pandolfini L, Savino A, Arcucci V, et al. MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging. BMC Biol. 2017;15:9 pubmed publisher
Shumilov A, Tsai M, Schlosser Y, Kratz A, Bernhardt K, Fink S, et al. Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat Commun. 2017;8:14257 pubmed publisher
Ercan E, Han J, Di Nardo A, Winden K, Han M, Hoyo L, et al. Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex. J Exp Med. 2017;214:681-697 pubmed publisher
Korotkevich E, Niwayama R, Courtois A, Friese S, Berger N, Buchholz F, et al. The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Dev Cell. 2017;40:235-247.e7 pubmed publisher
Drannik A, MARTIN J, Peterson R, Ma X, Jiang F, Turnbull J. Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function. PLoS ONE. 2017;12:e0171668 pubmed publisher
Pankova K, Borst A. Transgenic line for the identification of cholinergic release sites in Drosophila melanogaster. J Exp Biol. 2017;220:1405-1410 pubmed publisher
Holmes D, Heine V. Simplified 3D protocol capable of generating early cortical neuroepithelium. Biol Open. 2017;6:402-406 pubmed publisher
Dumont N, Rudnicki M. Characterizing Satellite Cells and Myogenic Progenitors During Skeletal Muscle Regeneration. Methods Mol Biol. 2017;1560:179-188 pubmed publisher
Wilde J, Siegenthaler J, Dent S, Niswander L. Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling. J Neurosci. 2017;37:2565-2579 pubmed publisher
García Heredia J, Lucena Cacace A, Verdugo Sivianes E, Pérez M, Carnero A. The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB. Clin Cancer Res. 2017;23:3871-3883 pubmed publisher
Loomis Z, Eigenberger P, Redinius K, Lisk C, Karoor V, Nozik Grayck E, et al. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS ONE. 2017;12:e0171219 pubmed publisher
Zalis M, Johansson S, Englund Johansson U. Immunocytochemical Profiling of Cultured Mouse Primary Retinal Cells. J Histochem Cytochem. 2017;65:223-239 pubmed publisher
Liang Z, Li W, Liu J, Li J, He F, Jiang Y, et al. Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells. Sci Rep. 2017;7:41776 pubmed publisher
Rader E, Naimo M, Ensey J, Baker B. Agonist muscle adaptation accompanied by antagonist muscle atrophy in the hindlimb of mice following stretch-shortening contraction training. BMC Musculoskelet Disord. 2017;18:60 pubmed publisher
Hogarth M, Houweling P, Thomas K, Gordish Dressman H, Bello L, Pegoraro E, et al. Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy. Nat Commun. 2017;8:14143 pubmed publisher
Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed publisher
González Rodríguez S, Álvarez M, Garcia Dominguez M, Lastra A, Cernuda Cernuda R, Folgueras A, et al. Hyperalgesic and hypoalgesic mechanisms evoked by the acute administration of CCL5 in mice. Brain Behav Immun. 2017;62:151-161 pubmed publisher
Milioto C, Malena A, Maino E, Polanco M, Marchioretti C, Borgia D, et al. Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes. Sci Rep. 2017;7:41046 pubmed publisher
Cao Z, Hong R, Ding B, Zuo X, Li H, Ding J, et al. TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos. PLoS ONE. 2017;12:e0169092 pubmed publisher
Erudaitius D, Huang A, Kazmi S, Buettner G, Rodgers V. Peroxiporin Expression Is an Important Factor for Cancer Cell Susceptibility to Therapeutic H2O2: Implications for Pharmacological Ascorbate Therapy. PLoS ONE. 2017;12:e0170442 pubmed publisher
Igarashi K, Kobayashi J, Katsumura T, Urushihara Y, Hida K, Watanabe Asaka T, et al. An Approach to Elucidate NBS1 Function in DNA Repair Using Frequent Nonsynonymous Polymorphism in Wild Medaka (Oryzias latipes) Populations. PLoS ONE. 2017;12:e0170006 pubmed publisher
Varadi J, Harazin A, Fenyvesi F, Réti Nagy K, Gogolak P, Vámosi G, et al. Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers. PLoS ONE. 2017;12:e0170537 pubmed publisher
Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed publisher
Ertsås H, Nolan G, Labarge M, Lorens J. Microsphere cytometry to interrogate microenvironment-dependent cell signaling. Integr Biol (Camb). 2017;9:123-134 pubmed publisher
Lee H, Diaz M, Price K, Ozuna J, Zhang S, Sevick Muraca E, et al. Fluid shear stress activates YAP1 to promote cancer cell motility. Nat Commun. 2017;8:14122 pubmed publisher
Benito Jardón M, Klapproth S, Gimeno LLuch I, Petzold T, Bharadwaj M, Müller D, et al. The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. elife. 2017;6: pubmed publisher
Borgia D, Malena A, Spinazzi M, Desbats M, Salviati L, Russell A, et al. Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum Mol Genet. 2017;26:1087-1103 pubmed publisher
Redmann M, Wani W, Volpicelli Daley L, Darley Usmar V, Zhang J. Trehalose does not improve neuronal survival on exposure to alpha-synuclein pre-formed fibrils. Redox Biol. 2017;11:429-437 pubmed publisher
Pietrocola F, Demont Y, Castoldi F, Enot D, Durand S, Semeraro M, et al. Metabolic effects of fasting on human and mouse blood in vivo. Autophagy. 2017;13:567-578 pubmed publisher
Sørensen K, Meldgaard T, Melchjorsen C, Fridriksdottir A, Pedersen H, Petersen O, et al. Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections. BMC Cancer. 2017;17:19 pubmed publisher
Muralidharan B, Khatri Z, Maheshwari U, Gupta R, Roy B, Pradhan S, et al. LHX2 Interacts with the NuRD Complex and Regulates Cortical Neuron Subtype Determinants Fezf2 and Sox11. J Neurosci. 2017;37:194-203 pubmed publisher
Masurkar A, Srinivas K, Brann D, Warren R, Lowes D, Siegelbaum S. Medial and Lateral Entorhinal Cortex Differentially Excite Deep versus Superficial CA1 Pyramidal Neurons. Cell Rep. 2017;18:148-160 pubmed publisher
Dergilev K, Makarevich P, Tsokolaeva Z, Boldyreva M, Beloglazova I, Zubkova E, et al. Comparison of cardiac stem cell sheets detached by Versene solution and from thermoresponsive dishes reveals similar properties of constructs. Tissue Cell. 2017;49:64-71 pubmed publisher
Erekat N. Cerebellar Purkinje cells die by apoptosis in the shaker mutant rat. Brain Res. 2017;1657:323-332 pubmed publisher
Horvath P, Kavalali E, Monteggia L. CRISPR/Cas9 system-mediated impairment of synaptobrevin/VAMP function in postmitotic hippocampal neurons. J Neurosci Methods. 2017;278:57-64 pubmed publisher
Takeshita Y, Obermeier B, Cotleur A, Spampinato S, Shimizu F, Yamamoto E, et al. Effects of neuromyelitis optica-IgG at the blood-brain barrier in vitro. Neurol Neuroimmunol Neuroinflamm. 2017;4:e311 pubmed publisher
Plugis N, Palanski B, Weng C, Albertelli M, Khosla C. Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: IMPLICATIONS FOR CELIAC DISEASE. J Biol Chem. 2017;292:2000-2008 pubmed publisher
Di Russo J, Luik A, Yousif L, Budny S, Oberleithner H, Hofschröer V, et al. Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J. 2017;36:183-201 pubmed publisher
Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, et al. Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis. Biochim Biophys Acta Mol Basis Dis. 2017;1863:560-568 pubmed publisher
Hayashi Y, Nemoto Sasaki Y, Matsumoto N, Tanikawa T, Oka S, Tanaka Y, et al. Carboxyl-terminal Tail-mediated Homodimerizations of Sphingomyelin Synthases Are Responsible for Efficient Export from the Endoplasmic Reticulum. J Biol Chem. 2017;292:1122-1141 pubmed publisher
D Lima N, Ma J, Winkler L, Chu Q, Loh K, Corpuz E, et al. A human microprotein that interacts with the mRNA decapping complex. Nat Chem Biol. 2017;13:174-180 pubmed publisher
Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed publisher
Kung Y, Hung C, Chien K, Shih S. Control of the negative IRES trans-acting factor KHSRP by ubiquitination. Nucleic Acids Res. 2017;45:271-287 pubmed publisher
St Jean Pelletier F, Pion C, Leduc Gaudet J, Sgarioto N, Zovilé I, Barbat Artigas S, et al. The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men. J Cachexia Sarcopenia Muscle. 2017;8:213-228 pubmed publisher
Coster A, Thorne C, Wu L, Altschuler S. Examining Crosstalk among Transforming Growth Factor β, Bone Morphogenetic Protein, and Wnt Pathways. J Biol Chem. 2017;292:244-250 pubmed publisher
Noor S, Pouyssegur J, Deitmer J, Becker H. Integration of a 'proton antenna' facilitates transport activity of the monocarboxylate transporter MCT4. FEBS J. 2017;284:149-162 pubmed publisher
Akbalik G, Langebeck Jensen K, Tushev G, Sambandan S, Rinne J, Epstein I, et al. Visualization of newly synthesized neuronal RNA in vitro and in vivo using click-chemistry. RNA Biol. 2017;14:20-28 pubmed publisher
Li Jessen N, Powell M, Choi A, Lee B, Thibeault S. Cellular source and proinflammatory roles of high-mobility group box 1 in surgically injured rat vocal folds. Laryngoscope. 2017;127:E193-E200 pubmed publisher
Kunzler A, Zeidán Chuliá F, Gasparotto J, Girardi C, Klafke K, Petiz L, et al. Changes in Cell Cycle and Up-Regulation of Neuronal Markers During SH-SY5Y Neurodifferentiation by Retinoic Acid are Mediated by Reactive Species Production and Oxidative Stress. Mol Neurobiol. 2017;54:6903-6916 pubmed publisher
Unruhe Knauf B, Knauer S. Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization. Methods Mol Biol. 2017;1510:47-59 pubmed
Achuta V, Grym H, Putkonen N, Louhivuori V, Kärkkäinen V, Koistinaho J, et al. Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome. Dev Neurobiol. 2017;77:438-453 pubmed publisher
Czulkies B, Mastroianni J, Lutz L, Lang S, Schwan C, Schmidt G, et al. Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells. Oncotarget. 2017;8:37009-37022 pubmed publisher
Park K, Luo X, Mooney S, Yungher B, Belin S, Wang C, et al. Retinal ganglion cell survival and axon regeneration after optic nerve injury in naked mole-rats. J Comp Neurol. 2017;525:380-388 pubmed publisher
Zheng Q, Zheng X, Zhang L, Luo H, Qian L, Fu X, et al. The Neuron-Specific Protein TMEM59L Mediates Oxidative Stress-Induced Cell Death. Mol Neurobiol. 2017;54:4189-4200 pubmed publisher
Mangiamele L, Gomez J, Curtis N, Thompson R. GPER/GPR30, a membrane estrogen receptor, is expressed in the brain and retina of a social fish (Carassius auratus) and colocalizes with isotocin. J Comp Neurol. 2017;525:252-270 pubmed publisher
Wierzbicka J, Zmijewski M, Antoniewicz J, Sobjanek M, Slominski A. Differentiation of Keratinocytes Modulates Skin HPA Analog. J Cell Physiol. 2017;232:154-66 pubmed publisher
Gouron R, Petit L, Boudot C, Six I, Brazier M, Kamel S, et al. Osteoclasts and their precursors are present in the induced-membrane during bone reconstruction using the Masquelet technique. J Tissue Eng Regen Med. 2017;11:382-389 pubmed publisher
Kudryavtseva A, Fedorova M, Zhavoronkov A, Moskalev A, Zasedatelev A, Dmitriev A, et al. Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells. BMC Genet. 2016;17:156 pubmed publisher
Neubauer H, Pitson S. Validation of commercially available sphingosine kinase 2 antibodies for use in immunoblotting, immunoprecipitation and immunofluorescence. F1000Res. 2016;5:2825 pubmed publisher
Wang P, Cui J, Wen J, Guo Y, Zhang L, Chen X. Cisplatin induces HepG2 cell cycle arrest through targeting specific long noncoding RNAs and the p53 signaling pathway. Oncol Lett. 2016;12:4605-4612 pubmed publisher
Ye Y, Zhao Z, Xu H, Zhang X, Su X, Yang Y, et al. Activation of Sphingosine 1-Phosphate Receptor 1 Enhances Hippocampus Neurogenesis in a Rat Model of Traumatic Brain Injury: An Involvement of MEK/Erk Signaling Pathway. Neural Plast. 2016;2016:8072156 pubmed publisher
Fall B, Scott C, Mauer M, Shankland S, Pippin J, Jefferson J, et al. Urinary Podocyte Loss Is Increased in Patients with Fabry Disease and Correlates with Clinical Severity of Fabry Nephropathy. PLoS ONE. 2016;11:e0168346 pubmed publisher
Yi Z, Ma X, Liang Q, Zhang T, Xu Z, Meng T, et al. Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes. Sci Rep. 2016;6:38574 pubmed publisher
Wang A, Jensen E, Rexach J, Vinters H, Hsieh Wilson L. Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration. Proc Natl Acad Sci U S A. 2016;113:15120-15125 pubmed publisher
Dinulovic I, Furrer R, Beer M, Ferry A, Cardel B, Handschin C. Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche. Skelet Muscle. 2016;6:39 pubmed
Shen M, Jiang Y, Guan Z, Cao Y, Sun S, Liu H. FSH protects mouse granulosa cells from oxidative damage by repressing mitophagy. Sci Rep. 2016;6:38090 pubmed publisher
Schober A, Gagarkin D, Chen Y, Gao G, Jacobson L, Mongin A. Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo. Front Cell Neurosci. 2016;10:262 pubmed
Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher
Formica F, Öztürk E, Hess S, Stark W, Maniura Weber K, Rottmar M, et al. A Bioinspired Ultraporous Nanofiber-Hydrogel Mimic of the Cartilage Extracellular Matrix. Adv Healthc Mater. 2016;5:3129-3138 pubmed publisher
Yuan H, Sehgal P. MxA Is a Novel Regulator of Endosome-Associated Transcriptional Signaling by Bone Morphogenetic Proteins 4 and 9 (BMP4 and BMP9). PLoS ONE. 2016;11:e0166382 pubmed publisher
Childs A, Vesely C, Ensell L, Lowe H, Luong T, Caplin M, et al. Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours. Br J Cancer. 2016;115:1540-1547 pubmed publisher
Scharaw S, Iskar M, Ori A, Boncompain G, Laketa V, Poser I, et al. The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR. J Cell Biol. 2016;215:543-558 pubmed
Hu Y, Zou Y, Huang Y, Zhang Y, Lourenco G, Chen S, et al. ROCK1 Is Associated with Alzheimer's Disease-Specific Plaques, as well as Enhances Autophagosome Formation But not Autophagic A? Clearance. Front Cell Neurosci. 2016;10:253 pubmed
Wu X, Wu X, Ma Y, Shao F, Tan Y, Tan T, et al. CUG-binding protein 1 regulates HSC activation and liver fibrogenesis. Nat Commun. 2016;7:13498 pubmed publisher
Sizemore T, Dacks A. Serotonergic Modulation Differentially Targets Distinct Network Elements within the Antennal Lobe of Drosophila melanogaster. Sci Rep. 2016;6:37119 pubmed publisher
Poncelet L, Garigliany M, Ando K, Franssen M, Desmecht D, Brion J. Cell cycle S phase markers are expressed in cerebral neuron nuclei of cats infected by the Feline Panleukopenia Virus. Cell Cycle. 2016;15:3482-3489 pubmed publisher
Berryer M, Chattopadhyaya B, Xing P, Riebe I, Bosoi C, Sanon N, et al. Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function. Nat Commun. 2016;7:13340 pubmed publisher
Ulmschneider B, Grillo Hill B, Benitez M, Azimova D, Barber D, Nystul T. Increased intracellular pH is necessary for adult epithelial and embryonic stem cell differentiation. J Cell Biol. 2016;215:345-355 pubmed
Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed
Pamarthy S, Mao L, Katara G, Fleetwood S, Kulshreshta A, Gilman Sachs A, et al. The V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling. Cell Death Dis. 2016;7:e2443 pubmed publisher
Lee J, Cho H, Lee J, Jun S, Ahn J, Min J, et al. Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis. Oncotarget. 2016;7:79774-79786 pubmed publisher
Newton A, Schnittker R, Yu Z, Munday S, Baumann D, Neaves W, et al. Widespread failure to complete meiosis does not impair fecundity in parthenogenetic whiptail lizards. Development. 2016;143:4486-4494 pubmed
Govero J, Esakky P, Scheaffer S, Fernandez E, Drury A, Platt D, et al. Zika virus infection damages the testes in mice. Nature. 2016;540:438-442 pubmed publisher
Lim J, Kim H, Nguyen K, Cho K. The role of TLR9 in stress-dependent autophagy formation. Biochem Biophys Res Commun. 2016;481:219-226 pubmed publisher
von Döhren J. Development of the Nervous System of Carinina ochracea (Palaeonemer-tea, Nemertea). PLoS ONE. 2016;11:e0165649 pubmed publisher
Stepien B, Oppitz C, Gerlach D, Dag U, Novatchkova M, Krüttner S, et al. RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2. Proc Natl Acad Sci U S A. 2016;113:E7030-E7038 pubmed publisher
Ujihara Y, Mohri S, Katanosaka Y. Effects of induced Na+/Ca2+ exchanger overexpression on the spatial distribution of L-type Ca2+ channels and junctophilin-2 in pressure-overloaded hearts. Biochem Biophys Res Commun. 2016;480:564-569 pubmed publisher
Dey N, Ramesh P, Chugh M, Mandal S, Mandal L. Dpp dependent Hematopoietic stem cells give rise to Hh dependent blood progenitors in larval lymph gland of Drosophila. elife. 2016;5: pubmed publisher
Davis F, Lloyd Lewis B, Harris O, Kozar S, Winton D, Muresan L, et al. Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny. Nat Commun. 2016;7:13053 pubmed publisher
Fisher J, Horst A, WAN T, Kim M, Auchampach J, Lough J. Depletion of Tip60 from In Vivo Cardiomyocytes Increases Myocyte Density, Followed by Cardiac Dysfunction, Myocyte Fallout and Lethality. PLoS ONE. 2016;11:e0164855 pubmed publisher
Bryukhovetskiy I, Dyuizen I, Shevchenko V, Bryukhovetskiy A, Mischenko P, Milkina E, et al. Hematopoietic stem cells as a tool for the treatment of glioblastoma multiforme. Mol Med Rep. 2016;14:4511-4520 pubmed publisher
Zheng X, Yang P, Lackford B, Bennett B, Wang L, Li H, et al. CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State. Stem Cell Reports. 2016;7:897-910 pubmed publisher
Li Y, Shen Y, Hohensinner P, Ju J, Wen Z, Goodman S, et al. Deficient Activity of the Nuclease MRE11A Induces T Cell Aging and Promotes Arthritogenic Effector Functions in Patients with Rheumatoid Arthritis. Immunity. 2016;45:903-916 pubmed publisher
Adotevi N, Leitch B. Alterations in AMPA receptor subunit expression in cortical inhibitory interneurons in the epileptic stargazer mutant mouse. Neuroscience. 2016;339:124-138 pubmed publisher
Forrest C, McNair K, Vincenten M, Darlington L, Stone T. Selective depletion of tumour suppressors Deleted in Colorectal Cancer (DCC) and neogenin by environmental and endogenous serine proteases: linking diet and cancer. BMC Cancer. 2016;16:772 pubmed
Phillips N, Manning C, Pettini T, Biga V, Marinopoulou E, Stanley P, et al. Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation. elife. 2016;5: pubmed publisher
Muraro M, Dharmadhikari G, Grün D, Groen N, Dielen T, Jansen E, et al. A Single-Cell Transcriptome Atlas of the Human Pancreas. Cell Syst. 2016;3:385-394.e3 pubmed publisher
Alexander M, Gasperini M, Tsai P, Gibbs D, Spinazzola J, Marshall J, et al. Reversal of neurobehavioral social deficits in dystrophic mice using inhibitors of phosphodiesterases PDE5A and PDE9A. Transl Psychiatry. 2016;6:e901 pubmed publisher
Mahgoub M, Adachi M, Suzuki K, Liu X, Kavalali E, Chahrour M, et al. MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviors. Nat Neurosci. 2016;19:1506-1512 pubmed publisher
Sadick J, Boutin M, Hoffman Kim D, Darling E. Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations. Sci Rep. 2016;6:33999 pubmed publisher
Bestard Escalas J, Garate J, Maimó Barceló A, Fernandez R, Lopez D, Lage S, et al. Lipid fingerprint image accurately conveys human colon cell pathophysiologic state: A solid candidate as biomarker. Biochim Biophys Acta. 2016;1861:1942-1950 pubmed publisher
Lin C, Huang S, Tung C, Chou C, Gau S, Huang H. Analysis of Genome-Wide Monoallelic Expression Patterns in Three Major Cell Types of Mouse Visual Cortex Using Laser Capture Microdissection. PLoS ONE. 2016;11:e0163663 pubmed publisher
Barik A, Li L, Sathyamurthy A, Xiong W, Mei L. Schwann Cells in Neuromuscular Junction Formation and Maintenance. J Neurosci. 2016;36:9770-81 pubmed publisher
Lund P, Elias J, Davis M. Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells. J Immunol. 2016;197:3086-3098 pubmed
Webb B, White K, Grillo Hill B, Schönichen A, Choi C, Barber D. A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity. J Biol Chem. 2016;291:24096-24104 pubmed
Lauritzen K, Hasan Olive M, Regnell C, Kleppa L, Scheibye Knudsen M, Gjedde A, et al. A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. Neurobiol Aging. 2016;48:34-47 pubmed publisher
Neggers J, Vanstreels E, Baloglu E, Shacham S, Landesman Y, Daelemans D. Heterozygous mutation of cysteine528 in XPO1 is sufficient for resistance to selective inhibitors of nuclear export. Oncotarget. 2016;7:68842-68850 pubmed publisher
Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher
Kim J, Chae J, Cheon Y, Kim C. Reciprocal localization of transcription factors YY1 and CP2c in spermatogonial stem cells and their putative roles during spermatogenesis. Acta Histochem. 2016;118:685-692 pubmed publisher
Aare S, Spendiff S, Vuda M, Elkrief D, Pérez A, Wu Q, et al. Failed reinnervation in aging skeletal muscle. Skelet Muscle. 2016;6:29 pubmed publisher
Jaako K, Waniek A, Parik K, Klimaviciusa L, Aonurm Helm A, Noortoots A, et al. Prolyl endopeptidase is involved in the degradation of neural cell adhesion molecules in vitro. J Cell Sci. 2016;129:3792-3802 pubmed
Loh K, Stawski P, Draycott A, Udeshi N, Lehrman E, Wilton D, et al. Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts. Cell. 2016;166:1295-1307.e21 pubmed publisher
Feringa F, Krenning L, Koch A, van den Berg J, van den Broek B, Jalink K, et al. Hypersensitivity to DNA damage in antephase as a safeguard for genome stability. Nat Commun. 2016;7:12618 pubmed publisher
Gnazzo M, Uhlemann E, Villarreal A, Shirayama M, Dominguez E, Skop A. The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4. Mol Biol Cell. 2016;27:3052-3064 pubmed
Larrayoz I, Rey Funes M, Contartese D, Rolón F, Sarotto A, Dorfman V, et al. Cold Shock Proteins Are Expressed in the Retina Following Exposure to Low Temperatures. PLoS ONE. 2016;11:e0161458 pubmed publisher
Soeda S, Yamada Nomoto K, Ohsugi M. The microtubule-binding and coiled-coil domains of Kid are required to turn off the polar ejection force at anaphase. J Cell Sci. 2016;129:3609-3619 pubmed
Lin M, Liu H, Xiong Q, Niu H, Cheng Z, Yamamoto A, et al. Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase. Autophagy. 2016;12:2145-2166 pubmed
Tazi M, Dakhlallah D, Caution K, Gerber M, Chang S, Khalil H, et al. Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages. Autophagy. 2016;12:2026-2037 pubmed
Cheng C, Nowak R, Biswas S, Lo W, FitzGerald P, Fowler V. Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells. Invest Ophthalmol Vis Sci. 2016;57:4084-99 pubmed publisher
Gaudet A, Mandrekar Colucci S, Hall J, Sweet D, Schmitt P, Xu X, et al. miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair. J Neurosci. 2016;36:8516-32 pubmed publisher
Song S, Kim K, Jo E, Kim Y, Kwon J, Bae S, et al. Fibroblast Growth Factor 12 Is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate. Arterioscler Thromb Vasc Biol. 2016;36:1928-36 pubmed publisher
Tome M, Herndon J, Schaefer C, Jacobs L, Zhang Y, Jarvis C, et al. P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain. J Cereb Blood Flow Metab. 2016;36:1913-1928 pubmed
Camacho E, Mesa Pereira B, Medina C, Flores A, Santero E. Engineering Salmonella as intracellular factory for effective killing of tumour cells. Sci Rep. 2016;6:30591 pubmed publisher
Yim N, Ryu S, Choi K, Lee K, Lee S, Choi H, et al. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun. 2016;7:12277 pubmed publisher
Snapkov I, Oqvist C, Figenschau Y, Kogner P, Johnsen J, Sveinbjørnsson B. The role of formyl peptide receptor 1 (FPR1) in neuroblastoma tumorigenesis. BMC Cancer. 2016;16:490 pubmed publisher
Dauleh S, Santeramo I, Fielding C, Ward K, Herrmann A, Murray P, et al. Characterisation of Cultured Mesothelial Cells Derived from the Murine Adult Omentum. PLoS ONE. 2016;11:e0158997 pubmed publisher
Minter M, Moore Z, Zhang M, Brody K, Jones N, Shultz S, et al. Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype. Acta Neuropathol Commun. 2016;4:72 pubmed publisher
Planaguma J, Haselmann H, Mannara F, Petit Pedrol M, Grünewald B, Aguilar E, et al. Ephrin-B2 prevents N-methyl-D-aspartate receptor antibody effects on memory and neuroplasticity. Ann Neurol. 2016;80:388-400 pubmed publisher
Torres Vega E, Duran Moreno M, Sánchez del Pino M, Yañez Y, Canete A, Castel V, et al. Immunoproteomic studies on paediatric opsoclonus-myoclonus associated with neuroblastoma. J Neuroimmunol. 2016;297:98-102 pubmed publisher
Di Liberto D, Mansueto P, D Alcamo A, Lo Pizzo M, Lo Presti E, Geraci G, et al. Predominance of Type 1 Innate Lymphoid Cells in the Rectal Mucosa of Patients With Non-Celiac Wheat Sensitivity: Reversal After a Wheat-Free Diet. Clin Transl Gastroenterol. 2016;7:e178 pubmed publisher
Marceau C, Puschnik A, Majzoub K, Ooi Y, Brewer S, Fuchs G, et al. Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens. Nature. 2016;535:159-63 pubmed
Leclercq S, Sullivan M, Ipe D, Smith J, Cripps A, Ulett G. Pathogenesis of Streptococcus urinary tract infection depends on bacterial strain and ?-hemolysin/cytolysin that mediates cytotoxicity, cytokine synthesis, inflammation and virulence. Sci Rep. 2016;6:29000 pubmed publisher
Hornstein N, Torres D, Das Sharma S, Tang G, Canoll P, Sims P. Ligation-free ribosome profiling of cell type-specific translation in the brain. Genome Biol. 2016;17:149 pubmed publisher
Sakano D, Choi S, Kataoka M, Shiraki N, Uesugi M, Kume K, et al. Dopamine D2 Receptor-Mediated Regulation of Pancreatic ? Cell Mass. Stem Cell Reports. 2016;7:95-109 pubmed publisher
Seo H, Jeong H, Joo H, Choi S, Park C, Kim J, et al. Intrinsic FGF2 and FGF5 promotes angiogenesis of human aortic endothelial cells in 3D microfluidic angiogenesis system. Sci Rep. 2016;6:28832 pubmed publisher
Chaubey P, Hofstetter L, Roschitzki B, Stieger B. Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver. PLoS ONE. 2016;11:e0158033 pubmed publisher
Grün D, Muraro M, Boisset J, Wiebrands K, Lyubimova A, Dharmadhikari G, et al. De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data. Cell Stem Cell. 2016;19:266-277 pubmed publisher
Dutta A, Le Magnen C, Mitrofanova A, Ouyang X, Califano A, Abate Shen C. Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation. Science. 2016;352:1576-80 pubmed publisher
Sanongkiet S, Ponnikorn S, Udomsangpetch R, Tungpradabkul S. Burkholderia pseudomallei rpoS mediates iNOS suppression in human hepatocyte (HC04) cells. FEMS Microbiol Lett. 2016;363: pubmed publisher
Yang Z, Xiong F, Wang Y, Gong W, Huang J, Chen C, et al. TGR5 activation suppressed S1P/S1P2 signaling and resisted high glucose-induced fibrosis in glomerular mesangial cells. Pharmacol Res. 2016;111:226-236 pubmed publisher
Viana da Silva S, Haberl M, Zhang P, Bethge P, Lemos C, Gonçalves N, et al. Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors. Nat Commun. 2016;7:11915 pubmed publisher
Pierron M, Pinan Lucarré B, Bessereau J. Preventing Illegitimate Extrasynaptic Acetylcholine Receptor Clustering Requires the RSU-1 Protein. J Neurosci. 2016;36:6525-37 pubmed publisher
Li Q, Karim A, Ding X, Das B, Dobrowolski C, Gibson R, et al. Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis. Sci Rep. 2016;6:27566 pubmed publisher
Dugmonits K, Ferencz A, Zahorán S, Lázár R, Talapka P, Orvos H, et al. Elevated levels of macromolecular damage are correlated with increased nitric oxide synthase expression in erythrocytes isolated from twin neonates. Br J Haematol. 2016;174:932-41 pubmed publisher
Dedkov E, Bogatyryov Y, Pavliak K, Santos A, Chen Y, Zhang Y, et al. Sex-related differences in intrinsic myocardial properties influence cardiac function in middle-aged rats during infarction-induced left ventricular remodeling. Physiol Rep. 2016;4: pubmed publisher
Liao H, Lee H, Chang Y, Lin C, Liu T, Chen Y, et al. Down-regulated and Commonly mutated ALPK1 in Lung and Colorectal Cancers. Sci Rep. 2016;6:27350 pubmed publisher
Bento C, Ashkenazi A, Jimenez Sanchez M, Rubinsztein D. The Parkinson's disease-associated genes ATP13A2 and SYT11 regulate autophagy via a common pathway. Nat Commun. 2016;7:11803 pubmed publisher
Marin Zapata P, Beese C, Jünger A, Dalmasso G, Brady N, Hamacher Brady A. Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation. BMC Cancer. 2016;16:355 pubmed publisher
Krey J, Drummond M, Foster S, Porsov E, Vijayakumar S, Choi D, et al. Annexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function. Sci Rep. 2016;6:27221 pubmed publisher
Wisnovsky S, Jean S, Kelley S. Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes. Nat Chem Biol. 2016;12:567-73 pubmed publisher
Nwadozi E, Roudier E, Rullman E, Tharmalingam S, Liu H, Gustafsson T, et al. Endothelial FoxO proteins impair insulin sensitivity and restrain muscle angiogenesis in response to a high-fat diet. FASEB J. 2016;30:3039-52 pubmed publisher
Kelly J, Esseltine J, Shao Q, Jabs E, SAMPSON J, Auranen M, et al. Specific functional pathologies of Cx43 mutations associated with oculodentodigital dysplasia. Mol Biol Cell. 2016;27:2172-85 pubmed publisher
Shu L, Sun W, Li L, Xu Z, Lin L, Xie P, et al. Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease. BMC Genomics. 2016;17:381 pubmed publisher
Condro M, Matynia A, Foster N, Ago Y, Rajbhandari A, Van C, et al. High-resolution characterization of a PACAP-EGFP transgenic mouse model for mapping PACAP-expressing neurons. J Comp Neurol. 2016;524:3827-3848 pubmed publisher
Ma S, Fang Z, Luo W, Yang Y, Wang C, Zhang Q, et al. The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity. Oxid Med Cell Longev. 2016;2016:4693703 pubmed publisher
Wharton K, Quigley C, Themeles M, Dunstan R, Doyle K, Cahir McFarland E, et al. JC Polyomavirus Abundance and Distribution in Progressive Multifocal Leukoencephalopathy (PML) Brain Tissue Implicates Myelin Sheath in Intracerebral Dissemination of Infection. PLoS ONE. 2016;11:e0155897 pubmed publisher
Zhang L, Cui Z, Zhou L, Kang Y, Li L, Li J, et al. Developing a Triple Transgenic Cell Line for High-Efficiency Porcine Reproductive and Respiratory Syndrome Virus Infection. PLoS ONE. 2016;11:e0154238 pubmed publisher
Ting W, Yang J, Kuo C, Xiao Z, Lu X, Yeh Y, et al. Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts. Oncotarget. 2016;7:39017-39025 pubmed publisher
Chauvigné F, Fjelldal P, Cerdà J, Finn R. Auto-Adhesion Potential of Extraocular Aqp0 during Teleost Development. PLoS ONE. 2016;11:e0154592 pubmed publisher
Li J, Hardy K, Phetsouphanh C, Tu W, Sutcliffe E, McCuaig R, et al. Nuclear PKC-? facilitates rapid transcriptional responses in human memory CD4+ T cells through p65 and H2B phosphorylation. J Cell Sci. 2016;129:2448-61 pubmed publisher
Blech Hermoni Y, Sullivan C, Jenkins M, Wessely O, Ladd A. CUG-BP, Elav-like family member 1 (CELF1) is required for normal myofibrillogenesis, morphogenesis, and contractile function in the embryonic heart. Dev Dyn. 2016;245:854-73 pubmed publisher
Yang E, Tacchelly Benites O, Wang Z, Randall M, Tian A, Benchabane H, et al. Wnt pathway activation by ADP-ribosylation. Nat Commun. 2016;7:11430 pubmed publisher
Li X, Wang Y, Wang H, Liu T, Guo J, Yi W, et al. Epithelia-derived wingless regulates dendrite directional growth of drosophila ddaE neuron through the Fz-Fmi-Dsh-Rac1 pathway. Mol Brain. 2016;9:46 pubmed publisher
Kang Y, Roife D, Lee Y, Lv H, Suzuki R, Ling J, et al. Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors. Clin Cancer Res. 2016;22:4934-4946 pubmed
Kayamori K, Katsube K, Sakamoto K, Ohyama Y, Hirai H, Yukimori A, et al. NOTCH3 Is Induced in Cancer-Associated Fibroblasts and Promotes Angiogenesis in Oral Squamous Cell Carcinoma. PLoS ONE. 2016;11:e0154112 pubmed publisher
Buren C, Tu G, Parsons M, Sepers M, Raymond L. Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture. J Neurophysiol. 2016;116:380-90 pubmed publisher
Bolt C, Negi S, Guimarães Camboa N, Zhang H, Troy J, Lu X, et al. Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS ONE. 2016;11:e0154413 pubmed publisher
Ren M, Du C, Herrero Acero E, Tang Schomer M, Ozkucur N. A biofidelic 3D culture model to study the development of brain cellular systems. Sci Rep. 2016;6:24953 pubmed publisher
Stewart M, Plante I, Penuela S, Laird D. Loss of Panx1 Impairs Mammary Gland Development at Lactation: Implications for Breast Tumorigenesis. PLoS ONE. 2016;11:e0154162 pubmed publisher
Lee Y, De Vadder F, Tremaroli V, Wichmann A, Mithieux G, Backhed F. Insulin-like peptide 5 is a microbially regulated peptide that promotes hepatic glucose production. Mol Metab. 2016;5:263-270 pubmed publisher
Grachev P, Porter K, Coolen L, McCosh R, Connors J, Hileman S, et al. Surge-Like Luteinising Hormone Secretion Induced by Retrochiasmatic Area NK3R Activation is Mediated Primarily by Arcuate Kisspeptin Neurones in the Ewe. J Neuroendocrinol. 2016;28: pubmed publisher
Kumar R, Narasimhan M, Shanmugam G, Hong J, Devarajan A, Palaniappan S, et al. Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress. J Transl Med. 2016;14:86 pubmed publisher
Tkachenko L, Zykin P, Nasyrov R, Krasnoshchekova E. Distinctive Features of the Human Marginal Zone and Cajal-Retzius Cells: Comparison of Morphological and Immunocytochemical Features at Midgestation. Front Neuroanat. 2016;10:26 pubmed publisher
Huang J, Chen M, Du J, Liu H, He Y, Li G, et al. Differential Expression of Adenosine P1 Receptor ADORA1 and ADORA2A Associated with Glioma Development and Tumor-Associated Epilepsy. Neurochem Res. 2016;41:1774-83 pubmed publisher
Kommagani R, Szwarc M, Vasquez Y, Peavey M, Mazur E, Gibbons W, et al. The Promyelocytic Leukemia Zinc Finger Transcription Factor Is Critical for Human Endometrial Stromal Cell Decidualization. PLoS Genet. 2016;12:e1005937 pubmed publisher
Estomba H, Muñoa Hoyos I, Gianzo M, Urizar Arenaza I, Casis L, Irazusta J, et al. Expression and Localization of Opioid Receptors in Male Germ Cells and the Implication for Mouse Spermatogenesis. PLoS ONE. 2016;11:e0152162 pubmed publisher
Urrego D, Movsisyan N, Ufartes R, Pardo L. Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells. Cell Cycle. 2016;15:799-811 pubmed publisher
Binder Z, Wilson K, Salmasi V, Orr B, Eberhart C, Siu I, et al. Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines. PLoS ONE. 2016;11:e0150271 pubmed publisher
Chatelle C, Hövermann D, Muller A, Wagner H, Weber W, Radziwill G. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep. 2016;6:23713 pubmed publisher
Trembley M, Velasquez L, Small E. Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration. J Vis Exp. 2016;: pubmed publisher
Lavrov I, Fox L, Shen J, Han Y, Cheng J. Gap Junctions Contribute to the Regulation of Walking-Like Activity in the Adult Mudpuppy (Necturus Maculatus). PLoS ONE. 2016;11:e0152650 pubmed publisher
Domínguez Calderón A, Ávila Flores A, Ponce A, López Bayghen E, Calderón Salinas J, Luis Reyes J, et al. ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway. Mol Biol Cell. 2016;27:1581-95 pubmed publisher
Stanley S, Kelly L, Latcha K, Schmidt S, Yu X, Nectow A, et al. Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism. Nature. 2016;531:647-50 pubmed publisher
Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed publisher
Abbassi L, Malki S, Cockburn K, Macaulay A, Robert C, Rossant J, et al. Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis. Biol Reprod. 2016;94:102 pubmed publisher
Zou L, Chen Q, Quanbeck Z, Bechtold J, Kaufman D. Angiogenic activity mediates bone repair from human pluripotent stem cell-derived osteogenic cells. Sci Rep. 2016;6:22868 pubmed publisher
Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher
Gao Y, Heldt S. Enrichment of GABAA Receptor α-Subunits on the Axonal Initial Segment Shows Regional Differences. Front Cell Neurosci. 2016;10:39 pubmed publisher
Wang Q, Fan A, Yuan Y, Chen L, Guo X, Huang X, et al. Role of Moesin in Advanced Glycation End Products-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells. Sci Rep. 2016;6:22749 pubmed publisher
Jin H, Ji M, Chen L, Liu Q, Che S, Xu M, et al. The clinicopathological significance of Mortalin overexpression in invasive ductal carcinoma of breast. J Exp Clin Cancer Res. 2016;35:42 pubmed publisher
McClatchey P, Keller A, Bouchard R, Knaub L, Reusch J. Raw and processed microscope images of fixed cells at baseline and following various experimental perturbations. Data Brief. 2016;6:998-1006 pubmed publisher
Ouimet M, Hennessy E, van Solingen C, Koelwyn G, Hussein M, Ramkhelawon B, et al. miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux. Arterioscler Thromb Vasc Biol. 2016;36:942-951 pubmed publisher
Datan E, Roy S, Germain G, Zali N, McLean J, Golshan G, et al. Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation. Cell Death Dis. 2016;7:e2127 pubmed publisher
Piras A, Collin L, Grüninger F, Graff C, Rönnbäck A. Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathol Commun. 2016;4:22 pubmed publisher
Wu J, Chi L, Chen Z, Lu X, Xiao S, Zhang G, et al. Functional analysis of the TMPRSS2:ERG fusion gene in cisplatin‑induced cell death. Mol Med Rep. 2016;13:3173-80 pubmed publisher
Leonhardt A, Ammer G, Meier M, Serbe E, Bahl A, Borst A. Asymmetry of Drosophila ON and OFF motion detectors enhances real-world velocity estimation. Nat Neurosci. 2016;19:706-15 pubmed publisher
Crisan M, Solaimani Kartalaei P, Neagu A, Karkanpouna S, Yamada Inagawa T, Purini C, et al. BMP and Hedgehog Regulate Distinct AGM Hematopoietic Stem Cells Ex Vivo. Stem Cell Reports. 2016;6:383-95 pubmed publisher
Zondler L, Müller K, Khalaji S, Bliederhäuser C, Ruf W, Grozdanov V, et al. Peripheral monocytes are functionally altered and invade the CNS in ALS patients. Acta Neuropathol. 2016;132:391-411 pubmed publisher
Tobita T, Guzman Lepe J, Takeishi K, Nakao T, Wang Y, Meng F, et al. SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. PLoS ONE. 2016;11:e0149344 pubmed publisher
D Amato Brito C, Cipriano D, Colin D, Germain S, Seimbille Y, Robert J, et al. Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma. Oncotarget. 2016;7:11512-25 pubmed publisher
Buniello A, Ingham N, Lewis M, Huma A, Martinez Vega R, Varela Nieto I, et al. Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing. EMBO Mol Med. 2016;8:191-207 pubmed publisher
Rohwedder A, Wenz N, Stehle B, Huser A, Yamagata N, Zlatic M, et al. Four Individually Identified Paired Dopamine Neurons Signal Reward in Larval Drosophila. Curr Biol. 2016;26:661-9 pubmed publisher
Wu T, Li Y, Liu B, Zhang S, Wu L, Zhu X, et al. Expression of Ferritin Light Chain (FTL) Is Elevated in Glioblastoma, and FTL Silencing Inhibits Glioblastoma Cell Proliferation via the GADD45/JNK Pathway. PLoS ONE. 2016;11:e0149361 pubmed publisher
Gumireddy K, Li A, Kossenkov A, Sakurai M, Yan J, Li Y, et al. The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis. Nat Commun. 2016;7:10715 pubmed publisher
Park J, Park J, Park D, Kim D, Kim H. Stem Cells Antigen-1 Enriches for a Cancer Stem Cell-Like Subpopulation in Mouse Gastric Cancer. Stem Cells. 2016;34:1177-87 pubmed publisher
Rácz Ã, Gaál B, Matesz C. Heterogeneous expression of extracellular matrix molecules in the red nucleus of the rat. Neuroscience. 2016;322:1-17 pubmed publisher
Kellner N, Schwarz J, Sturm M, Fernandez Martinez J, Griesel S, Zhang W, et al. Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies. Sci Rep. 2016;6:20937 pubmed publisher
Liao K, Guo M, Niu F, Yang L, Callen S, Buch S. Cocaine-mediated induction of microglial activation involves the ER stress-TLR2 axis. J Neuroinflammation. 2016;13:33 pubmed publisher
O Sullivan C, Schubart A, Mir A, Dev K. The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures. J Neuroinflammation. 2016;13:31 pubmed publisher
Gallardo Vara E, Blanco F, Roqué M, Friedman S, Suzuki T, Botella L, et al. Transcription factor KLF6 upregulates expression of metalloprotease MMP14 and subsequent release of soluble endoglin during vascular injury. Angiogenesis. 2016;19:155-71 pubmed publisher
Vincent K, Cornea V, Jong Y, Laferriere A, Kumar N, Mickeviciute A, et al. Intracellular mGluR5 plays a critical role in neuropathic pain. Nat Commun. 2016;7:10604 pubmed publisher
Zuccala E, Satchwell T, Angrisano F, Tan Y, Wilson M, Heesom K, et al. Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton. Sci Rep. 2016;6:19766 pubmed publisher
Dorris E, Blackshields G, Sommerville G, Alhashemi M, Dias A, McEneaney V, et al. Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines. Cancer Biol Ther. 2016;17:526-42 pubmed publisher
Liu X, Berry C, Ruthel G, Madara J, MacGillivray K, Gray C, et al. T Cell Receptor-induced Nuclear Factor κB (NF-κB) Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-mediated Calcium Entry. J Biol Chem. 2016;291:8440-52 pubmed publisher
Yan M, Zhu W, Zheng X, Li Y, Tang L, Lu B, et al. Effect of glutamate on lysosomal membrane permeabilization in primary cultured cortical neurons. Mol Med Rep. 2016;13:2499-505 pubmed publisher
Zhang Q, Dan J, Wang H, Guo R, Mao J, Fu H, et al. Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells. Sci Rep. 2016;6:19852 pubmed publisher
Jayachandran P, Olmo V, Sanchez S, McFarland R, Vital E, Werner J, et al. Microtubule-associated protein 1b is required for shaping the neural tube. Neural Dev. 2016;11:1 pubmed publisher
Grohar P, Kim S, Rangel Rivera G, Sen N, Haddock S, Harlow M, et al. Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma. Cell Rep. 2016;14:598-610 pubmed publisher
Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed publisher
Ito N, Hendriks W, Dhakal J, Vaine C, Liu C, Shin D, et al. Decreased N-TAF1 expression in X-linked dystonia-parkinsonism patient-specific neural stem cells. Dis Model Mech. 2016;9:451-62 pubmed publisher
Ma X, Lin F, Wang Z, Hu M, Huang L, Meng T, et al. Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility. Mol Biol Cell. 2016;27:768-75 pubmed publisher
Kono M, Heincke D, Wilcke L, Wong T, Bruns C, Herrmann S, et al. Pellicle formation in the malaria parasite. J Cell Sci. 2016;129:673-80 pubmed publisher
Samura M, Morikage N, Suehiro K, Tanaka Y, Nakamura T, Nishimoto A, et al. Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia. Sci Rep. 2016;6:19379 pubmed publisher
Jia L, Li J, He B, Jia Y, Niu Y, Wang C, et al. Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries. Sci Rep. 2016;6:19436 pubmed publisher
Li J, Chatzeli L, Panousopoulou E, Tucker A, Green J. Epithelial stratification and placode invagination are separable functions in early morphogenesis of the molar tooth. Development. 2016;143:670-81 pubmed publisher
Roth J, Köhler D, Schneider M, Granja T, Rosenberger P. Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury. PLoS ONE. 2016;11:e0146930 pubmed publisher
Maculins T, Carter N, Dorval T, Hudson K, Nissink J, Hay R, et al. A Generic Platform for Cellular Screening Against Ubiquitin Ligases. Sci Rep. 2016;6:18940 pubmed publisher
Forster J, Köglsberger S, Trefois C, Boyd O, Baumuratov A, Buck L, et al. Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability. J Biomol Screen. 2016;21:496-509 pubmed publisher
Maimets M, Rocchi C, Bron R, Pringle S, Kuipers J, Giepmans B, et al. Long-Term In Vitro Expansion of Salivary Gland Stem Cells Driven by Wnt Signals. Stem Cell Reports. 2016;6:150-62 pubmed publisher
Shopsowitz K, Wu C, Liu G, Dreaden E, Hammond P. Periodic-shRNA molecules are capable of gene silencing, cytotoxicity and innate immune activation in cancer cells. Nucleic Acids Res. 2016;44:545-57 pubmed publisher
Liu M, Yang H. WNT4-like protein is a cortical granule component in mouse oocytes and functions in regulating preimplantation embryogenesis. Syst Biol Reprod Med. 2016;62:49-56 pubmed publisher
Cisternas P, Louveau A, Bueno S, Kalergis A, Boudin H, Riedel C. Gestational Hypothyroxinemia Affects Glutamatergic Synaptic Protein Distribution and Neuronal Plasticity Through Neuron-Astrocyte Interplay. Mol Neurobiol. 2016;53:7158-7169 pubmed
Marquès Bueno M, Morao A, Cayrel A, Platre M, Barberon M, Caillieux E, et al. A versatile Multisite Gateway-compatible promoter and transgenic line collection for cell type-specific functional genomics in Arabidopsis. Plant J. 2016;85:320-333 pubmed publisher
Jiménez Pérez L, Cidad P, Álvarez Miguel I, Santos Hipólito A, Torres Merino R, Alonso E, et al. Molecular Determinants of Kv1.3 Potassium Channels-induced Proliferation. J Biol Chem. 2016;291:3569-80 pubmed publisher
Power G, Minozzo F, Spendiff S, Filion M, Konokhova Y, Purves Smith M, et al. Reduction in single muscle fiber rate of force development with aging is not attenuated in world class older masters athletes. Am J Physiol Cell Physiol. 2016;310:C318-27 pubmed publisher
Hellwig S, Brioschi S, Dieni S, Frings L, Masuch A, Blank T, et al. Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice. Brain Behav Immun. 2016;55:126-137 pubmed publisher
Lalanne T, Oyrer J, Mancino A, Gregor E, Chung A, Huynh L, et al. Synapse-specific expression of calcium-permeable AMPA receptors in neocortical layer 5. J Physiol. 2016;594:837-61 pubmed publisher
Horie R, Nakamura O, Yamagami Y, Mori M, Nishimura H, Fukuoka N, et al. Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells. Int J Oncol. 2016;48:37-44 pubmed publisher
Chatterjee S, Saj A, Gocha T, Murphy M, Gonsalves F, Zhang X, et al. Inhibition of β-catenin-TCF1 interaction delays differentiation of mouse embryonic stem cells. J Cell Biol. 2015;211:39-51 pubmed publisher
Xu M, Chung S, Zhang S, Zhong P, Ma C, Chang W, et al. Basal forebrain circuit for sleep-wake control. Nat Neurosci. 2015;18:1641-7 pubmed publisher
Chaudhary P, Marshall T, Currell F, Kacperek A, Schettino G, Prise K. Variations in the Processing of DNA Double-Strand Breaks Along 60-MeV Therapeutic Proton Beams. Int J Radiat Oncol Biol Phys. 2016;95:86-94 pubmed publisher
Taketa D, Nydam M, Langenbacher A, Rodriguez D, Sanders E, De Tomaso A. Molecular evolution and in vitro characterization of Botryllus histocompatibility factor. Immunogenetics. 2015;67:605-23 pubmed publisher
Chrysostomou A, Grady J, Laude A, Taylor R, Turnbull D, Lax N. Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease. Neuropathol Appl Neurobiol. 2016;42:477-92 pubmed publisher
Chance R, Bashaw G. Slit-Dependent Endocytic Trafficking of the Robo Receptor Is Required for Son of Sevenless Recruitment and Midline Axon Repulsion. PLoS Genet. 2015;11:e1005402 pubmed publisher
Bøje S, Olsen A, Erneholm K, Agerholm J, Jungersen G, Andersen P, et al. A multi-subunit Chlamydia vaccine inducing neutralizing antibodies and strong IFN-?? CMI responses protects against a genital infection in minipigs. Immunol Cell Biol. 2016;94:185-95 pubmed publisher
Ishiuchi T, Enriquez Gasca R, Mizutani E, Bošković A, Ziegler Birling C, Rodriguez Terrones D, et al. Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly. Nat Struct Mol Biol. 2015;22:662-71 pubmed publisher
Rohwedder A, Selcho M, Chassot B, Thum A. Neuropeptide F neurons modulate sugar reward during associative olfactory learning of Drosophila larvae. J Comp Neurol. 2015;523:2637-64 pubmed publisher
Gingras S, Earls L, Howell S, Smeyne R, Zakharenko S, Pelletier S. SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus. J Neurosci. 2015;35:10510-22 pubmed publisher
Evans T, Santiago C, Arbeille E, Bashaw G. Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons. elife. 2015;4:e08407 pubmed publisher
Jung E, Sim Y, Jeong H, Kim S, Yun Y, Song J, et al. Jmjd2C increases MyoD transcriptional activity through inhibiting G9a-dependent MyoD degradation. Biochim Biophys Acta. 2015;1849:1081-94 pubmed publisher
Kapuralin K, Ćurlin M, Mitrečić D, Kosi N, Schwarzer C, Glavan G, et al. STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons. Mol Cell Neurosci. 2015;67:104-15 pubmed publisher
Kaur G, Pinggera A, Ortner N, Lieb A, Sinnegger Brauns M, Yarov Yarovoy V, et al. A Polybasic Plasma Membrane Binding Motif in the I-II Linker Stabilizes Voltage-gated CaV1.2 Calcium Channel Function. J Biol Chem. 2015;290:21086-100 pubmed publisher
Fremont R, Tewari A, Khodakhah K. Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism. Neurobiol Dis. 2015;82:200-212 pubmed publisher
Fulga T, McNeill E, Binari R, Yelick J, Blanche A, Booker M, et al. A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs. Nat Commun. 2015;6:7279 pubmed publisher
Nimlamool W, Andrews R, Falk M. Connexin43 phosphorylation by PKC and MAPK signals VEGF-mediated gap junction internalization. Mol Biol Cell. 2015;26:2755-68 pubmed publisher
Leduc Gaudet J, Picard M, St Jean Pelletier F, Sgarioto N, Auger M, Vallée J, et al. Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice. Oncotarget. 2015;6:17923-37 pubmed
Lenoir O, Jasiek M, Henique C, Guyonnet L, Hartleben B, Bork T, et al. Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis. Autophagy. 2015;11:1130-45 pubmed publisher
van der Voet M, Harich B, Franke B, Schenck A. ADHD-associated dopamine transporter, latrophilin and neurofibromin share a dopamine-related locomotor signature in Drosophila. Mol Psychiatry. 2016;21:565-73 pubmed publisher
Viswanathan S, Williams M, Bloss E, Stasevich T, Speer C, Nern A, et al. High-performance probes for light and electron microscopy. Nat Methods. 2015;12:568-76 pubmed publisher
Briona L, Poulain F, Mosimann C, Dorsky R. Wnt/ß-catenin signaling is required for radial glial neurogenesis following spinal cord injury. Dev Biol. 2015;403:15-21 pubmed publisher
Mak P, Li J, Samanta S, Chang C, Jerry D, Davis R, et al. Prostate tumorigenesis induced by PTEN deletion involves estrogen receptor β repression. Cell Rep. 2015;10:1982-91 pubmed publisher
Severi F, Conticello S. Flow-cytometric visualization of C>U mRNA editing reveals the dynamics of the process in live cells. RNA Biol. 2015;12:389-97 pubmed publisher
Koch M, Varela L, Kim J, Kim J, Hernández Nuño F, Simonds S, et al. Hypothalamic POMC neurons promote cannabinoid-induced feeding. Nature. 2015;519:45-50 pubmed publisher
Gawlik Dziki U, Swieca M, Dziki D, Sęczyk Ł, Złotek U, Różyło R, et al. Anticancer and antioxidant activity of bread enriched with broccoli sprouts. Biomed Res Int. 2014;2014:608053 pubmed publisher
Faroni A, Smith R, Procacci P, Castelnovo L, Puccianti E, Reid A, et al. Purinergic signaling mediated by P2X7 receptors controls myelination in sciatic nerves. J Neurosci Res. 2014;92:1259-69 pubmed publisher
Selcho M, Pauls D, Huser A, Stocker R, Thum A. Characterization of the octopaminergic and tyraminergic neurons in the central brain of Drosophila larvae. J Comp Neurol. 2014;522:3485-500 pubmed publisher
Briona L, Dorsky R. Radial glial progenitors repair the zebrafish spinal cord following transection. Exp Neurol. 2014;256:81-92 pubmed publisher
Yim D, Ghosh S, Guy G, Virshup D. Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling. Oncogene. 2015;34:474-84 pubmed publisher
Peters H, Yan Y, Solheim J. APLP2 regulates the expression of MHC class I molecules on irradiated Ewing's sarcoma cells. Oncoimmunology. 2013;2:e26293 pubmed
Palavicini J, Lloyd B, Hayes C, Bianchi E, Kang D, Dawson Scully K, et al. RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice. PLoS ONE. 2013;8:e66908 pubmed publisher
Lauritzen H, Brandauer J, Schjerling P, Koh H, Treebak J, Hirshman M, et al. Contraction and AICAR stimulate IL-6 vesicle depletion from skeletal muscle fibers in vivo. Diabetes. 2013;62:3081-92 pubmed publisher
Ott C, Elia N, Jeong S, Insinna C, Sengupta P, Lippincott Schwartz J. Primary cilia utilize glycoprotein-dependent adhesion mechanisms to stabilize long-lasting cilia-cilia contacts. Cilia. 2012;1:3 pubmed publisher
Manning C, Bundros A, Trimmer J. Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importance. PLoS ONE. 2012;7:e38313 pubmed publisher
Selcho M, Pauls D, El Jundi B, Stocker R, Thum A. The role of octopamine and tyramine in Drosophila larval locomotion. J Comp Neurol. 2012;520:3764-85 pubmed publisher
Tran H, Sanchez L, Brody D. Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice. J Neuropathol Exp Neurol. 2012;71:116-29 pubmed publisher
Simpson D, Yu M, Zheng S, Zhao Z, Muthuswamy S, Tansey W. Epithelial cell organization suppresses Myc function by attenuating Myc expression. Cancer Res. 2011;71:3822-30 pubmed publisher
Cho J, Chen L, Kim M, Chow R, Hille B, Koh D. Characteristics and functions of {alpha}-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors expressed in mouse pancreatic {alpha}-cells. Endocrinology. 2010;151:1541-50 pubmed publisher
Gendronneau G, Sidhu S, Delacour D, Dang T, Calonne C, Houzelstein D, et al. Galectin-7 in the control of epidermal homeostasis after injury. Mol Biol Cell. 2008;19:5541-9 pubmed publisher
Pittman A, Law M, Chien C. Pathfinding in a large vertebrate axon tract: isotypic interactions guide retinotectal axons at multiple choice points. Development. 2008;135:2865-71 pubmed publisher
Liu Y, Taverna S, Muratore T, Shabanowitz J, Hunt D, Allis C. RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena. Genes Dev. 2007;21:1530-45 pubmed
Weller C, Collington S, Brown J, Miller H, Al Kashi A, Clark P, et al. Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors. J Exp Med. 2005;201:1961-71 pubmed
product information
Product Type :
Secondary Antibody
Product Name :
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
Catalog # :
A-11008
Quantity :
1 mg
Price :
US 196
Clonality :
Polyclonal
Purity :
purified
Host :
Goat
Reactivity :
Rabbit
Applications :
Flow Cytometry: 1-10 µg/mL, Immunocytochemistry: 4 µg/mL, Immunofluorescence: 4 µg/mL, Immunohistochemistry: Assay Dependent
Species :
Rabbit
Isotype :
IgG
Storage :
4° C, store in dark
Description :
Anti-Rabbit secondary antibodies are affinity-purified antibodies with well-characterized specificity for rabbit immunoglobulins and are useful in the detection, sorting or purification of its specified target. Secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody. Most commonly, secondary antibodies are generated by immunizing the host animal with a pooled population of immunoglobulins from the target species and can be further purified and modified (i.e. immunoaffinity chromatography, antibody fragmentation, label conjugation, etc.) to generate highly specific reagents.
Immunogen :
Gamma Immunoglobins Heavy and Light chains
Format :
liquid
Applications w/Dilutions :
Flow Cytometry: 1-10 µg/mL, Immunocytochemistry: 4 µg/mL, Immunofluorescence: 4 µg/mL, Immunohistochemistry: Assay Dependent
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA