Reference |
---|
Deutsch M, Gunther A, Lerchundi R, Rose C, Balfanz S, Baumann A. AAV-Mediated CRISPRi and RNAi Based Gene Silencing in Mouse Hippocampal Neurons. Cells. 2021;10: pubmed publisher
|
Shorrocks A, Jones S, Tsukada K, Morrow C, Belblidia Z, Shen J, et al. The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks. Nat Commun. 2021;12:585 pubmed publisher
|
Kanoldt V, Kluger C, Barz C, Schweizer A, Ramanujam D, Windgasse L, et al. Metavinculin modulates force transduction in cell adhesion sites. Nat Commun. 2020;11:6403 pubmed publisher
|
Somayaji M, Cataldi S, Choi S, Edwards R, Mosharov E, Sulzer D. A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo. Proc Natl Acad Sci U S A. 2020;117:32701-32710 pubmed publisher
|
Girardi E, Agrimi G, Goldmann U, Fiume G, Lindinger S, Sedlyarov V, et al. Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import. Nat Commun. 2020;11:6145 pubmed publisher
|
Zhou X, Zhong Y, Molinar Inglis O, Kunkel M, Chen M, Sun T, et al. Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Nat Commun. 2020;11:6088 pubmed publisher
|
Hultgren N, Fang J, Ziegler M, Ramirez R, Phan D, Hatch M, et al. Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis. Nat Commun. 2020;11:5400 pubmed publisher
|
Parry D, Tamayo Orrego L, Carroll P, Marsh J, Greene P, Murina O, et al. PRIM1 deficiency causes a distinctive primordial dwarfism syndrome. Genes Dev. 2020;: pubmed publisher
|
Escalona R, Bilandzic M, Western P, Kadife E, Kannourakis G, Findlay J, et al. TIMP-2 regulates proliferation, invasion and STAT3-mediated cancer stem cell-dependent chemoresistance in ovarian cancer cells. BMC Cancer. 2020;20:960 pubmed publisher
|
Lindhout F, Kooistra R, Portegies S, Herstel L, Stucchi R, Snoek B, et al. Quantitative mapping of transcriptome and proteome dynamics during polarization of human iPSC-derived neurons. elife. 2020;9: pubmed publisher
|
Yamulla R, Nalubola S, Flesken Nikitin A, Nikitin A, Schimenti J. Most Commonly Mutated Genes in High-Grade Serous Ovarian Carcinoma Are Nonessential for Ovarian Surface Epithelial Stem Cell Transformation. Cell Rep. 2020;32:108086 pubmed publisher
|
Bondarieva A, Raveendran K, Telychko V, Rao H, Ravindranathan R, Zorzompokou C, et al. Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Nat Commun. 2020;11:3101 pubmed publisher
|
Bobkov G, Huang A, van den Berg S, Mitra S, Anselm E, Lazou V, et al. Spt6 is a maintenance factor for centromeric CENP-A. Nat Commun. 2020;11:2919 pubmed publisher
|
Bikbaev A, Ciuraszkiewicz Wojciech A, Heck J, Klatt O, Freund R, Mitlöhner J, et al. Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development. J Neurosci. 2020;40:4824-4841 pubmed publisher
|
Noda T, Lu Y, Fujihara Y, Oura S, Koyano T, Kobayashi S, et al. Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice. Proc Natl Acad Sci U S A. 2020;117:11493-11502 pubmed publisher
|
Bensimon A, Pizzagalli M, Kartnig F, Dvorak V, Essletzbichler P, Winter G, et al. Targeted Degradation of SLC Transporters Reveals Amenability of Multi-Pass Transmembrane Proteins to Ligand-Induced Proteolysis. Cell Chem Biol. 2020;27:728-739.e9 pubmed publisher
|
Kojima Y, Machida Y, Palani S, Caulfield T, Radisky E, Kaufmann S, et al. FAM111A protects replication forks from protein obstacles via its trypsin-like domain. Nat Commun. 2020;11:1318 pubmed publisher
|
Miyawaki T, Morikawa S, Susaki E, Nakashima A, Takeuchi H, Yamaguchi S, et al. Visualization and molecular characterization of whole-brain vascular networks with capillary resolution. Nat Commun. 2020;11:1104 pubmed publisher
|
Mizunoe Y, Kobayashi M, Hoshino S, Tagawa R, Itagawa R, Hoshino A, et al. Cathepsin B overexpression induces degradation of perilipin 1 to cause lipid metabolism dysfunction in adipocytes. Sci Rep. 2020;10:634 pubmed publisher
|
Shibata Germanos S, Goodman J, Grieg A, Trivedi C, Benson B, Foti S, et al. Structural and functional conservation of non-lumenized lymphatic endothelial cells in the mammalian leptomeninges. Acta Neuropathol. 2020;139:383-401 pubmed publisher
|
Liu P, Shuaib M, Zhang H, Nadeef S, Orlando V. Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1α/β-mediated adaptive stress response pathway in skeletal muscle cells. Epigenetics Chromatin. 2019;12:78 pubmed publisher
|
Travisano S, Oliveira V, Prados B, Grego Bessa J, Piñeiro Sabarís R, Bou V, et al. Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. elife. 2019;8: pubmed publisher
|
Yuva Aydemir Y, Almeida S, Krishnan G, Gendron T, Gao F. Transcription elongation factor AFF2/FMR2 regulates expression of expanded GGGGCC repeat-containing C9ORF72 allele in ALS/FTD. Nat Commun. 2019;10:5466 pubmed publisher
|
Odle R, Walker S, Oxley D, Kidger A, Balmanno K, Gilley R, et al. An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis. Mol Cell. 2019;: pubmed publisher
|
Randzavola L, Strege K, Juzans M, Asano Y, Stinchcombe J, Gawden Bone C, et al. Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity. J Clin Invest. 2019;129:5600-5614 pubmed publisher
|
Palanisamy N, Degen A, Morath A, Ballestin Ballestin J, Juraske C, Ozturk M, et al. Split intein-mediated selection of cells containing two plasmids using a single antibiotic. Nat Commun. 2019;10:4967 pubmed publisher
|
Allen S, Hall B, Woof R, Francis L, Gatto N, Shaw A, et al. C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis. Brain. 2019;142:3771-3790 pubmed publisher
|
Malaise O, Tachikart Y, Constantinides M, Mumme M, Ferreira Lopez R, Noack S, et al. Mesenchymal stem cell senescence alleviates their intrinsic and seno-suppressive paracrine properties contributing to osteoarthritis development. Aging (Albany NY). 2019;11:9128-9146 pubmed publisher
|
Antinucci P, Folgueira M, Bianco I. Pretectal neurons control hunting behaviour. elife. 2019;8: pubmed publisher
|
Gooding S, Olechnowicz S, Morris E, Armitage A, Arezes J, Frost J, et al. Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease. Nat Commun. 2019;10:4533 pubmed publisher
|
Okuno K, Naito Y, Yasumura S, Sawada H, Asakura M, Masuyama T, et al. Haploinsufficiency of Transferrin Receptor 1 Impairs Angiogenesis with Reduced Mitochondrial Complex I in Mice with Limb Ischemia. Sci Rep. 2019;9:13658 pubmed publisher
|
Morris J, Yashinskie J, Koche R, Chandwani R, Tian S, Chen C, et al. α-Ketoglutarate links p53 to cell fate during tumour suppression. Nature. 2019;573:595-599 pubmed publisher
|
van Senten J, Bebelman M, Fan T, Heukers R, Bergkamp N, van Gasselt P, et al. The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties. J Biol Chem. 2019;294:16297-16308 pubmed publisher
|
Fang P, De Souza C, Minn K, Chien J. Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity. Commun Biol. 2019;2:335 pubmed publisher
|
Liu W, Ganguly A, Huang J, Wang Y, Ni J, Gurav A, et al. Neuropeptide F regulates courtship in Drosophila through a male-specific neuronal circuit. elife. 2019;8: pubmed publisher
|
Yeoh L, Goodman C, Mollard V, McHugh E, Lee V, Sturm A, et al. Alternative splicing is required for stage differentiation in malaria parasites. Genome Biol. 2019;20:151 pubmed publisher
|
Lang J, Toulmin S, Brida K, Eisenlohr L, Davidson B. Standard screening methods underreport AAV-mediated transduction and gene editing. Nat Commun. 2019;10:3415 pubmed publisher
|
Faraj T, Stover C, Erridge C. Dietary Toll-Like Receptor Stimulants Promote Hepatic Inflammation and Impair Reverse Cholesterol Transport in Mice via Macrophage-Dependent Interleukin-1 Production. Front Immunol. 2019;10:1404 pubmed publisher
|
Bullock B, Kimball A, Poczobutt J, Neuwelt A, Li H, Johnson A, et al. Tumor-intrinsic response to IFNγ shapes the tumor microenvironment and anti-PD-1 response in NSCLC. Life Sci Alliance. 2019;2: pubmed publisher
|
Skedsmo F, Tranulis M, Espenes A, Prydz K, Matiasek K, Gunnes G, et al. Cell and context-dependent sorting of neuropathy-associated protein NDRG1 - insights from canine tissues and primary Schwann cell cultures. BMC Vet Res. 2019;15:121 pubmed publisher
|
Ho P, Leung C, Liu H, Pang S, Lam C, Xian J, et al. Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). Autophagy. 2019;:1-24 pubmed publisher
|
Yang Y, Vassilakos G, Hammers D, Yang Z, Barton E, SWEENEY H. Smooth muscle atrophy and colon pathology in SMN deficient mice. Am J Transl Res. 2019;11:1789-1799 pubmed
|
Koster K, Francesconi W, Berton F, Alahmadi S, Srinivas R, Yoshii A. Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model. elife. 2019;8: pubmed publisher
|
Kumar R, Duhamel M, Coutant E, Ben Nahia E, Mercier R. Antagonism between BRCA2 and FIGL1 regulates homologous recombination. Nucleic Acids Res. 2019;47:5170-5180 pubmed publisher
|
Shoemaker C, Huang T, Weir N, Polyakov N, Schultz S, Denic V. CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor. PLoS Biol. 2019;17:e2007044 pubmed publisher
|
Lacin H, Chen H, Long X, Singer R, Lee T, Truman J. Neurotransmitter identity is acquired in a lineage-restricted manner in the Drosophila CNS. elife. 2019;8: pubmed publisher
|
Yamawaki N, Li X, Lambot L, Ren L, Radulovic J, Shepherd G. Long-range inhibitory intersection of a retrosplenial thalamocortical circuit by apical tuft-targeting CA1 neurons. Nat Neurosci. 2019;22:618-626 pubmed publisher
|
Tradtrantip L, Duan T, Yeaman M, Verkman A. CD55 upregulation in astrocytes by statins as potential therapy for AQP4-IgG seropositive neuromyelitis optica. J Neuroinflammation. 2019;16:57 pubmed publisher
|
Sainz de Aja J, Menchero S, Rollán I, Barral A, Tiana M, Jawaid W, et al. The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1. EMBO J. 2019;38: pubmed publisher
|
Bianco J, Bergoglio V, Lin Y, Pillaire M, Schmitz A, Gilhodes J, et al. Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner. Nat Commun. 2019;10:910 pubmed publisher
|
Pan X, Cao Y, Stucchi R, Hooikaas P, Portegies S, Will L, et al. MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon. Cell Rep. 2019;26:1988-1999.e6 pubmed publisher
|
Monroe T, Hill M, Morikawa Y, Leach J, Heallen T, Cao S, et al. YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. Dev Cell. 2019;48:765-779.e7 pubmed publisher
|
Tobita T, Kiyozumi D, Muto M, Noda T, Ikawa M. Lvrn expression is not critical for mouse placentation. J Reprod Dev. 2019;65:239-244 pubmed publisher
|
Lehane A, Dennis A, Bray K, Li D, Rajendran E, McCoy J, et al. Characterization of the ATP4 ion pump in Toxoplasma gondii. J Biol Chem. 2019;294:5720-5734 pubmed publisher
|
Giannios I, Serafimidis I, Anastasiou V, Pezzolla D, Lesche M, Andree C, et al. Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression. Stem Cells. 2019;37:640-651 pubmed publisher
|
Spence E, Dube S, Uezu A, Locke M, Soderblom E, Soderling S. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun. 2019;10:386 pubmed publisher
|
Spitzer S, Sitnikov S, Kamen Y, Evans K, Kronenberg Versteeg D, Dietmann S, et al. Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age. Neuron. 2019;101:459-471.e5 pubmed publisher
|
Weckbach L, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, et al. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med. 2019;216:350-368 pubmed publisher
|
Schilling T, Ali A, Leonhardt A, Borst A, Pujol Martí J. Transcriptional control of morphological properties of direction-selective T4/T5 neurons in Drosophila. Development. 2019;146: pubmed publisher
|
Byrum A, Carvajal Maldonado D, Mudge M, Valle García D, Majid M, Patel R, et al. Mitotic regulators TPX2 and Aurora A protect DNA forks during replication stress by counteracting 53BP1 function. J Cell Biol. 2019;218:422-432 pubmed publisher
|
Cortés E, Lachowski D, Robinson B, Sarper M, Teppo J, Thorpe S, et al. Tamoxifen mechanically reprograms the tumor microenvironment via HIF-1A and reduces cancer cell survival. EMBO Rep. 2019;20: pubmed publisher
|
Bancells C, Llorà Batlle O, Poran A, Nötzel C, Rovira Graells N, Elemento O, et al. Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum. Nat Microbiol. 2019;4:144-154 pubmed publisher
|
Walter S, Jumpertz T, Hüttenrauch M, Ogorek I, Gerber H, Storck S, et al. The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's disease. Acta Neuropathol. 2019;137:239-257 pubmed publisher
|
Dias M, Fonseca C, Zeidler J, Albuquerque L, Da Silva M, Cararo Lopes E, et al. Fibroblast Growth Factor 2 lethally sensitizes cancer cells to stress-targeted therapeutic inhibitors. Mol Oncol. 2019;13:290-306 pubmed publisher
|
Motterlini R, Nikam A, Manin S, Ollivier A, Wilson J, Djouadi S, et al. HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide. Redox Biol. 2019;20:334-348 pubmed publisher
|
Tornillo G, Knowlson C, Kendrick H, Cooke J, Mirza H, Aurrekoetxea Rodríguez I, et al. Dual Mechanisms of LYN Kinase Dysregulation Drive Aggressive Behavior in Breast Cancer Cells. Cell Rep. 2018;25:3674-3692.e10 pubmed publisher
|
Lambert L, Dubayle D, Fafouri A, Herzog E, Csaba Z, Dournaud P, et al. Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway. Front Cell Neurosci. 2018;12:450 pubmed publisher
|
Rosenberg L, Cattin A, Fontana X, Harford Wright E, Burden J, White I, et al. HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. Cell Rep. 2018;25:2755-2765.e5 pubmed publisher
|
Olthoff J, Lindsay A, Abo Zahrah R, Baltgalvis K, Patrinostro X, Belanto J, et al. Loss of peroxiredoxin-2 exacerbates eccentric contraction-induced force loss in dystrophin-deficient muscle. Nat Commun. 2018;9:5104 pubmed publisher
|
Plesch E, Chen C, Butz E, Scotto Rosato A, Krogsaeter E, Yinan H, et al. Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells. elife. 2018;7: pubmed publisher
|
Zhuang L, Lawlor K, Schlueter H, Pieterse Z, Yu Y, Kaur P. Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions. Life Sci Alliance. 2018;1:e201700009 pubmed publisher
|
Paul E, Kalk E, Tossell K, Irvine E, Franks N, Wisden W, et al. nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta. Eneuro. 2018;5: pubmed publisher
|
Oh J, Lee S, Rothstein R, Symington L. Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability. Cell Rep. 2018;25:1681-1692.e4 pubmed publisher
|
Billin A, Honeycutt S, McDougal A, Kerr J, Chen Z, Freudenberg J, et al. HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury. Skelet Muscle. 2018;8:35 pubmed publisher
|
Dahimene S, Page K, Kadurin I, Ferron L, Ho D, Powell G, et al. The α2δ-like Protein Cachd1 Increases N-type Calcium Currents and Cell Surface Expression and Competes with α2δ-1. Cell Rep. 2018;25:1610-1621.e5 pubmed publisher
|
Gonzalez L, Macdonald M, Deng Y, Trigatti B. Hyperglycemia Aggravates Diet-Induced Coronary Artery Disease and Myocardial Infarction in SR-B1-Knockout/ApoE-Hypomorphic Mice. Front Physiol. 2018;9:1398 pubmed publisher
|
Lee C, Kim H, Lee Y, Kang G, Lim H, Lee S, et al. Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation. Cell Rep. 2018;25:934-946.e5 pubmed publisher
|
Fang H, Gomes A, Klages N, Pino P, Maco B, Walker E, et al. Epistasis studies reveal redundancy among calcium-dependent protein kinases in motility and invasion of malaria parasites. Nat Commun. 2018;9:4248 pubmed publisher
|
Abreu C, Prakash R, Romanienko P, Roig I, Keeney S, Jasin M. Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination. Nat Commun. 2018;9:3961 pubmed publisher
|
Oladipupo S, Kabir A, Smith C, Choi K, Ornitz D. Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1). Sci Rep. 2018;8:14724 pubmed publisher
|
Balcerek J, Jiang J, Li Y, Jiang Q, Holdreith N, Singh B, et al. Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia. Nat Commun. 2018;9:3915 pubmed publisher
|
Gammage P, Viscomi C, Simard M, Costa A, Gaude E, Powell C, et al. Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nat Med. 2018;24:1691-1695 pubmed publisher
|
Chan C, Gulati G, Sinha R, Tompkins J, Lopez M, Carter A, et al. Identification of the Human Skeletal Stem Cell. Cell. 2018;175:43-56.e21 pubmed publisher
|
Köppert S, Büscher A, Babler A, Ghallab A, Buhl E, Latz E, et al. Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity. Front Immunol. 2018;9:1991 pubmed publisher
|
Galagovsky D, Depetris Chauvin A, Manière G, Geillon F, Berthelot Grosjean M, Noirot E, et al. Sobremesa L-type Amino Acid Transporter Expressed in Glia Is Essential for Proper Timing of Development and Brain Growth. Cell Rep. 2018;24:3156-3166.e4 pubmed publisher
|
Boucher M, Ghosh S, Zhang L, Lal A, Jang S, Ju A, et al. Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites. PLoS Biol. 2018;16:e2005895 pubmed publisher
|
Fabbiano S, Suárez Zamorano N, Chevalier C, Lazarevic V, Kieser S, Rigo D, et al. Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements. Cell Metab. 2018;28:907-921.e7 pubmed publisher
|
Alpar L, Bergantiños C, Johnston L. Spatially Restricted Regulation of Spätzle/Toll Signaling during Cell Competition. Dev Cell. 2018;46:706-719.e5 pubmed publisher
|
Singh K, Camera E, Krug L, Basu A, Pandey R, Munir S, et al. JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin. Nat Commun. 2018;9:3425 pubmed publisher
|
Colecchia D, Dapporto F, Tronnolone S, Salvini L, Chiariello M. MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process. J Biol Chem. 2018;293:15962-15976 pubmed publisher
|
Vay S, Flitsch L, Rabenstein M, Rogall R, Blaschke S, Kleinhaus J, et al. The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo. J Neuroinflammation. 2018;15:226 pubmed publisher
|
Dergilev K, Tsokolaeva Z, Makarevich P, Beloglazova I, Zubkova E, Boldyreva M, et al. C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats. Biomed Res Int. 2018;2018:3536854 pubmed publisher
|
Windler F, Bönigk W, Körschen H, Grahn E, Strünker T, Seifert R, et al. The solute carrier SLC9C1 is a Na+/H+-exchanger gated by an S4-type voltage-sensor and cyclic-nucleotide binding. Nat Commun. 2018;9:2809 pubmed publisher
|
Sun J, Liu Y, Jia Y, Hao X, Lin W, Tran J, et al. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. elife. 2018;7: pubmed publisher
|
Kahn O, Schätzle P, van de Willige D, Tas R, Lindhout F, Portegies S, et al. APC2 controls dendrite development by promoting microtubule dynamics. Nat Commun. 2018;9:2773 pubmed publisher
|
Singh B, Weaver C, Garry M, Garry D. Hedgehog and Wnt Signaling Pathways Regulate Tail Regeneration. Stem Cells Dev. 2018;27:1426-1437 pubmed publisher
|
Park S, Lee C, Lee J, Park J, Roshandell M, Brennan C, et al. Requirement for and polarized localization of integrin proteins during Drosophila wound closure. Mol Biol Cell. 2018;29:2137-2147 pubmed publisher
|
Georgilis A, Klotz S, Hanley C, Herranz N, Weirich B, Morancho B, et al. PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. Cancer Cell. 2018;34:85-102.e9 pubmed publisher
|
Fielding J, Hodson E, Cheng X, Ferguson D, Eckardt L, Adam J, et al. PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies. J Physiol. 2018;: pubmed publisher
|
Dong C, Helton E, Zhou P, Ouyang X, d Anglemont de Tassigny X, Pascual A, et al. Glial-derived neurotrophic factor is essential for blood-nerve barrier functional recovery in an experimental murine model of traumatic peripheral neuropathy. Tissue Barriers. 2018;6:1-22 pubmed publisher
|
Rowland M, Jiang Y, Beier F, Berube N. Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. Aging (Albany NY). 2018;10:1223-1238 pubmed publisher
|
Girnius N, Edwards Y, Garlick D, Davis R. The cJUN NH2-terminal kinase (JNK) signaling pathway promotes genome stability and prevents tumor initiation. elife. 2018;7: pubmed publisher
|
Niland S, Komljenovic D, Macas J, Bracht T, Bauerle T, Liebner S, et al. Rhodocetin-αβ selectively breaks the endothelial barrier of the tumor vasculature in HT1080 fibrosarcoma and A431 epidermoid carcinoma tumor models. Oncotarget. 2018;9:22406-22422 pubmed publisher
|
Li H, McSharry M, Walker D, Johnson A, Kwak J, Bullock B, et al. Targeted overexpression of prostacyclin synthase inhibits lung tumor progression by recruiting CD4+ T lymphocytes in tumors that express MHC class II. Oncoimmunology. 2018;7:e1423182 pubmed publisher
|
Aziz N, Guedj F, Pennings J, Olmos Serrano J, Siegel A, Haydar T, et al. Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome. Dis Model Mech. 2018;11: pubmed publisher
|
Corominas J, Colijn J, Geerlings M, Pauper M, Bakker B, Amin N, et al. Whole-Exome Sequencing in Age-Related Macular Degeneration Identifies Rare Variants in COL8A1, a Component of Bruch's Membrane. Ophthalmology. 2018;125:1433-1443 pubmed publisher
|
Igarashi H, Ikeda K, Onimaru H, Kaneko R, Koizumi K, Beppu K, et al. Targeted expression of step-function opsins in transgenic rats for optogenetic studies. Sci Rep. 2018;8:5435 pubmed publisher
|
Aleksandrov R, Dotchev A, Poser I, Krastev D, Georgiev G, Panova G, et al. Protein Dynamics in Complex DNA Lesions. Mol Cell. 2018;69:1046-1061.e5 pubmed publisher
|
Botusan I, Zheng X, Narayanan S, Grunler J, Sunkari V, Calissendorff F, et al. Deficiency of liver-derived insulin-like growth factor-I (IGF-I) does not interfere with the skin wound healing rate. PLoS ONE. 2018;13:e0193084 pubmed publisher
|
Kuwahara H, Song J, Shimoura T, Yoshida Tanaka K, Mizuno T, Mochizuki T, et al. Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo. Sci Rep. 2018;8:4377 pubmed publisher
|
Nascimento M, Sorokin L, Coelho Sampaio T. Fractone Bulbs Derive from Ependymal Cells and Their Laminin Composition Influence the Stem Cell Niche in the Subventricular Zone. J Neurosci. 2018;38:3880-3889 pubmed publisher
|
Girnius N, Edwards Y, Davis R. The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution. Cell Death Differ. 2018;25:1702-1715 pubmed publisher
|
Wasén C, Ekstrand M, Levin M, Giglio D. Epidermal growth factor receptor function in the human urothelium. Int Urol Nephrol. 2018;50:647-656 pubmed publisher
|
Dawes J, Weir G, Middleton S, Patel R, Chisholm K, Pettingill P, et al. Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability. Neuron. 2018;97:806-822.e10 pubmed publisher
|
Ebner P, Poetsch I, Deszcz L, Hoffmann T, Zuber J, Ikeda F. The IAP family member BRUCE regulates autophagosome-lysosome fusion. Nat Commun. 2018;9:599 pubmed publisher
|
Mrdjen D, Pavlovic A, Hartmann F, Schreiner B, Utz S, Leung B, et al. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity. 2018;48:380-395.e6 pubmed publisher
|
Dyer M, Chen Q, Haldeman S, Yazdani H, Hoffman R, Loughran P, et al. Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA. Sci Rep. 2018;8:2068 pubmed publisher
|
Jutten B, Keulers T, Peeters H, Schaaf M, Savelkouls K, Compter I, et al. EGFRvIII expression triggers a metabolic dependency and therapeutic vulnerability sensitive to autophagy inhibition. Autophagy. 2018;14:283-295 pubmed publisher
|
Stewart D, Marada S, Bodeen W, Truong A, Sakurada S, Pandit T, et al. Cleavage activates dispatched for Sonic Hedgehog ligand release. elife. 2018;7: pubmed publisher
|
Watanabe M, Narita M, Hamada Y, Yamashita A, Tamura H, Ikegami D, et al. Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer. Mol Pain. 2018;14:1744806918756406 pubmed publisher
|
Chang W, Lajko M, Fawzi A. Endothelin-1 is associated with fibrosis in proliferative diabetic retinopathy membranes. PLoS ONE. 2018;13:e0191285 pubmed publisher
|
Draper J, Sroczynska P, Fadlullah M, Patel R, Newton G, Breitwieser W, et al. A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects. PLoS Genet. 2018;14:e1007127 pubmed publisher
|
Nüchel J, Ghatak S, Zuk A, Illerhaus A, Morgelin M, Schönborn K, et al. TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators. Autophagy. 2018;14:465-486 pubmed publisher
|
Padgett L, Lentini J, Holmes M, Stilger K, Fu D, Sullivan W. Elp3 and RlmN: A tale of two mitochondrial tail-anchored radical SAM enzymes in Toxoplasma gondii. PLoS ONE. 2018;13:e0189688 pubmed publisher
|
Smith M, Harley M, Kemp A, Wills J, Lee M, Arends M, et al. CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis. Dev Cell. 2018;44:217-232.e11 pubmed publisher
|
Essig K, Hu D, Guimaraes J, Alterauge D, Edelmann S, Raj T, et al. Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells. Immunity. 2017;47:1067-1082.e12 pubmed publisher
|
Scherer P, Zaccor N, Neumann N, Vasavda C, Barrow R, Ewald A, et al. TRPV1 is a physiological regulator of μ-opioid receptors. Proc Natl Acad Sci U S A. 2017;114:13561-13566 pubmed publisher
|
Tas R, Chazeau A, Cloin B, Lambers M, Hoogenraad C, Kapitein L. Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport. Neuron. 2017;96:1264-1271.e5 pubmed publisher
|
Chamberlin T, D Amato J, Arendt L. Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res. 2017;19:128 pubmed publisher
|
Xian X, Ding Y, Dieckmann M, Zhou L, Plattner F, Liu M, et al. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. elife. 2017;6: pubmed publisher
|
Julio Kalajzić F, Villanueva S, Burgos J, Ojeda M, Cid L, Jentsch T, et al. K2P TASK-2 and KCNQ1/KCNE3 K+ channels are major players contributing to intestinal anion and fluid secretion. J Physiol. 2017;: pubmed publisher
|
Tamura N, Nishimura T, Sakamaki Y, Koyama Honda I, Yamamoto H, Mizushima N. Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets. FEBS Lett. 2017;591:3819-3830 pubmed publisher
|
Clark A, Leroy F, Martyniuk K, Feng W, McManus E, Bailey M, et al. Dopamine D2 Receptors in the Paraventricular Thalamus Attenuate Cocaine Locomotor Sensitization. Eneuro. 2017;4: pubmed publisher
|
Farhy Tselnicker I, van Casteren A, Lee A, Chang V, Aricescu A, Allen N. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Neuron. 2017;96:428-445.e13 pubmed publisher
|
Venkatachalam G, Surana U, Clement M. Replication stress-induced endogenous DNA damage drives cellular senescence induced by a sub-lethal oxidative stress. Nucleic Acids Res. 2017;45:10564-10582 pubmed publisher
|
Patel D, Misenko S, Her J, Bunting S. BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites. J Cell Biol. 2017;216:3521-3534 pubmed publisher
|
Böttcher R, Veelders M, Rombaut P, Faix J, Theodosiou M, Stradal T, et al. Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. J Cell Biol. 2017;216:3785-3798 pubmed publisher
|
Hope K, Ledoux M, Reiter L. Glial overexpression of Dube3a causes seizures and synaptic impairments in Drosophila concomitant with down regulation of the Na+/K+ pump ATP?. Neurobiol Dis. 2017;108:238-248 pubmed publisher
|
Shao L, Saver M, Chung P, Ren Q, Lee T, Kent C, et al. Dissection of the Drosophila neuropeptide F circuit using a high-throughput two-choice assay. Proc Natl Acad Sci U S A. 2017;114:E8091-E8099 pubmed publisher
|
Tsunematsu H, Uyeda A, Yamamoto N, Sugo N. Immunocytochemistry and fluorescence imaging efficiently identify individual neurons with CRISPR/Cas9-mediated gene disruption in primary cortical cultures. BMC Neurosci. 2017;18:55 pubmed publisher
|
Castillo Azofeifa D, Losacco J, Salcedo E, Golden E, Finger T, Barlow L. Sonic hedgehog from both nerves and epithelium is a key trophic factor for taste bud maintenance. Development. 2017;144:3054-3065 pubmed publisher
|
Li L, Zviti R, Ha C, Wang Z, Hill J, Lin F. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem. 2017;292:13774-13783 pubmed publisher
|
Yoon S, Kawasaki I, Shim Y. The B-type cyclin CYB-1 maintains the proper position and number of centrosomes during spermatogenesis in Caenorhabditis elegans. J Cell Sci. 2017;130:2722-2735 pubmed publisher
|
van Nierop G, van Luijn M, Michels S, Melief M, Janssen M, Langerak A, et al. Phenotypic and functional characterization of T cells in white matter lesions of multiple sclerosis patients. Acta Neuropathol. 2017;134:383-401 pubmed publisher
|
Hatakeyama J, Sato H, Shimamura K. Developing guinea pig brain as a model for cortical folding. Dev Growth Differ. 2017;59:286-301 pubmed publisher
|
Tai Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, et al. Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling. Development. 2017;144:2392-2401 pubmed publisher
|
Marino G, Santhiago M, Santhanam A, Lassance L, Thangavadivel S, Medeiros C, et al. Epithelial basement membrane injury and regeneration modulates corneal fibrosis after pseudomonas corneal ulcers in rabbits. Exp Eye Res. 2017;161:101-105 pubmed publisher
|
Natsume T, Nishimura K, Minocherhomji S, Bhowmick R, Hickson I, Kanemaki M. Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis. Genes Dev. 2017;31:816-829 pubmed publisher
|
Quadrato G, Nguyen T, Macosko E, Sherwood J, Min Yang S, Berger D, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53 pubmed publisher
|
Winder M, Vesela R, Aronsson P, Patel B, Carlsson T. Autonomic Receptor-mediated Regulation of Production and Release of Nitric Oxide in Normal and Malignant Human Urothelial Cells. Basic Clin Pharmacol Toxicol. 2017;121:257-265 pubmed publisher
|
Ge Y, Gomez N, Adam R, Nikolova M, Yang H, Verma A, et al. Stem Cell Lineage Infidelity Drives Wound Repair and Cancer. Cell. 2017;169:636-650.e14 pubmed publisher
|
Schludi M, Becker L, Garrett L, Gendron T, Zhou Q, Schreiber F, et al. Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss. Acta Neuropathol. 2017;134:241-254 pubmed publisher
|
Moshiri A, Humpal D, Leonard B, Imai D, Tham A, Bower L, et al. Arap1 Deficiency Causes Photoreceptor Degeneration in Mice. Invest Ophthalmol Vis Sci. 2017;58:1709-1718 pubmed publisher
|
Laporte M, Chatellard C, Vauchez V, Hemming F, Deloulme J, Vossier F, et al. Alix is required during development for normal growth of the mouse brain. Sci Rep. 2017;7:44767 pubmed publisher
|
Bohnacker T, Prota A, Beaufils F, Burke J, Melone A, Inglis A, et al. Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun. 2017;8:14683 pubmed publisher
|
Caberlotto E, Ruiz L, Miller Z, Poletti M, Tadlock L. Effects of a skin-massaging device on the ex-vivo expression of human dermis proteins and in-vivo facial wrinkles. PLoS ONE. 2017;12:e0172624 pubmed publisher
|
Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O Neil N, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017;8:14432 pubmed publisher
|
Rajendran E, Hapuarachchi S, Miller C, Fairweather S, Cai Y, Smith N, et al. Cationic amino acid transporters play key roles in the survival and transmission of apicomplexan parasites. Nat Commun. 2017;8:14455 pubmed publisher
|
Wang J, Lee J, Christian S, Dang Lawson M, Pritchard C, Freeman S, et al. The Rap1-cofilin-1 pathway coordinates actin reorganization and MTOC polarization at the B cell immune synapse. J Cell Sci. 2017;130:1094-1109 pubmed publisher
|
Dadson K, Hauck L, Hao Z, Grothe D, Rao V, Mak T, et al. The E3 ligase Mule protects the heart against oxidative stress and mitochondrial dysfunction through Myc-dependent inactivation of Pgc-1α and Pink1. Sci Rep. 2017;7:41490 pubmed publisher
|
Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher
|
Bharadwaj M, Strohmeyer N, Colo G, Helenius J, Beerenwinkel N, Schiller H, et al. αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin. Nat Commun. 2017;8:14348 pubmed publisher
|
Chen Z, Givens C, Reader J, Tzima E. Haemodynamics Regulate Fibronectin Assembly via PECAM. Sci Rep. 2017;7:41223 pubmed publisher
|
Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, et al. Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction. PLoS Genet. 2017;13:e1006578 pubmed publisher
|
Phillips A, Millet A, Tigano M, Dubois S, Crimmins H, Babin L, et al. Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion. Mol Cell. 2017;65:527-538.e6 pubmed publisher
|
González González M, Gómez González G, Becerra González M, Martinez Torres A. Identification of novel cellular clusters define a specialized area in the cerebellar periventricular zone. Sci Rep. 2017;7:40768 pubmed publisher
|
Tagal V, Wei S, Zhang W, Brekken R, Posner B, Peyton M, et al. SMARCA4-inactivating mutations increase sensitivity to Aurora kinase A inhibitor VX-680 in non-small cell lung cancers. Nat Commun. 2017;8:14098 pubmed publisher
|
Zhang J, Chen S, Cai J, Hou Z, Wang X, Kachelmeier A, et al. Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system. Hear Res. 2017;345:10-22 pubmed publisher
|
Zazo Seco C, Castells Nobau A, Joo S, Schraders M, Foo J, van der Voet M, et al. A homozygous FITM2 mutation causes a deafness-dystonia syndrome with motor regression and signs of ichthyosis and sensory neuropathy. Dis Model Mech. 2017;10:105-118 pubmed publisher
|
Guillot Sestier M, Weitz T, Town T. Quantitative 3D In Silico Modeling (q3DISM) of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease. J Vis Exp. 2016;: pubmed publisher
|
Lundell A, Nordström I, Andersson K, Lundqvist C, Telemo E, Nava S, et al. IFN type I and II induce BAFF secretion from human decidual stromal cells. Sci Rep. 2017;7:39904 pubmed publisher
|
Mórocz M, Zsigmond E, Toth R, Enyedi M, Pintér L, Haracska L. DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA. Nucleic Acids Res. 2017;45:3172-3188 pubmed publisher
|
Pascual G, Avgustinova A, Mejetta S, Martin M, Castellanos A, Attolini C, et al. Targeting metastasis-initiating cells through the fatty acid receptor CD36. Nature. 2017;541:41-45 pubmed publisher
|
Ganta V, Choi M, Kutateladze A, Annex B. VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease. Circ Res. 2017;120:282-295 pubmed publisher
|
Wang A, Jensen E, Rexach J, Vinters H, Hsieh Wilson L. Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration. Proc Natl Acad Sci U S A. 2016;113:15120-15125 pubmed publisher
|
Yamamoto K, Sato K, Yukita M, Yasuda M, Omodaka K, Ryu M, et al. The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection. J Neurochem. 2017;140:495-508 pubmed publisher
|
Mouillesseaux K, Wiley D, Saunders L, Wylie L, Kushner E, Chong D, et al. Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6. Nat Commun. 2016;7:13247 pubmed publisher
|
Shatirishvili M, Burk A, Franz C, Pace G, Kastilan T, Breuhahn K, et al. Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress. Cell Death Dis. 2016;7:e2461 pubmed publisher
|
Fröhlich D, Suchowerska A, Spencer Z, von Jonquieres G, Klugmann C, Bongers A, et al. In vivocharacterization of the aspartyl-tRNA synthetase DARS: Homing in on the leukodystrophy HBSL. Neurobiol Dis. 2017;97:24-35 pubmed publisher
|
Fujimura K, Mitsuhashi T, Shibata S, Shimozato S, Takahashi T. In Utero Exposure to Valproic Acid Induces Neocortical Dysgenesis via Dysregulation of Neural Progenitor Cell Proliferation/Differentiation. J Neurosci. 2016;36:10908-10919 pubmed
|
Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed
|
Davis F, Lloyd Lewis B, Harris O, Kozar S, Winton D, Muresan L, et al. Single-cell lineage tracing in the mammary gland reveals stochastic clonal dispersion of stem/progenitor cell progeny. Nat Commun. 2016;7:13053 pubmed publisher
|
Zheng X, Yang P, Lackford B, Bennett B, Wang L, Li H, et al. CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State. Stem Cell Reports. 2016;7:897-910 pubmed publisher
|
Rabbani M, Ribaudo M, Guo J, Barik S. Identification of Interferon-Stimulated Gene Proteins That Inhibit Human Parainfluenza Virus Type 3. J Virol. 2016;90:11145-11156 pubmed
|
Powis R, Karyka E, Boyd P, Côme J, Jones R, Zheng Y, et al. Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy. JCI Insight. 2016;1:e87908 pubmed publisher
|
Szunyogova E, Zhou H, Maxwell G, Powis R, Muntoni F, Gillingwater T, et al. Survival Motor Neuron (SMN) protein is required for normal mouse liver development. Sci Rep. 2016;6:34635 pubmed publisher
|
Okata S, Yuasa S, Suzuki T, Ito S, Makita N, Yoshida T, et al. Embryonic type Na+ channel ?-subunit, SCN3B masks the disease phenotype of Brugada syndrome. Sci Rep. 2016;6:34198 pubmed publisher
|
Li L, Chen J, Xiong G, St Clair D, Xu W, Xu R. Increased ROS production in non-polarized mammary epithelial cells induces monocyte infiltration in 3D culture. J Cell Sci. 2017;130:190-202 pubmed publisher
|
Foerster F, Bamberger D, Schupp J, Weilbächer M, Kaps L, Strobl S, et al. Dextran-based therapeutic nanoparticles for hepatic drug delivery. Nanomedicine (Lond). 2016;11:2663-2677 pubmed
|
Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Biol Open. 2016;5:1516-1529 pubmed publisher
|
Ren Q, Awasaki T, Huang Y, Liu Z, Lee T. Cell Class-Lineage Analysis Reveals Sexually Dimorphic Lineage Compositions in the Drosophila Brain. Curr Biol. 2016;26:2583-2593 pubmed publisher
|
Lim J, van der Pol S, Baron W, McCord J, de Vries H, van Horssen J. Protandim Protects Oligodendrocytes against an Oxidative Insult. Antioxidants (Basel). 2016;5: pubmed publisher
|
Ortuño M, Robinson S, Subramanyam P, Paone R, Huang Y, Guo X, et al. Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect. Nat Med. 2016;22:1170-1179 pubmed publisher
|
Xu H, Gelyana E, Rajsombath M, Yang T, Li S, Selkoe D. Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid ?-Protein Oligomers. J Neurosci. 2016;36:9041-56 pubmed publisher
|
Zhang X, Gaudry Q. Functional integration of a serotonergic neuron in the Drosophila antennal lobe. elife. 2016;5: pubmed publisher
|
Miranda M, Nascimento H, Costa M, Costa N, Brito K, Lopes C, et al. Increasing of blastocyst rate and gene expression in co-culture of bovine embryos with adult adipose tissue-derived mesenchymal stem cells. J Assist Reprod Genet. 2016;33:1395-1403 pubmed
|
Gammage P, Gaude E, Van Haute L, Rebelo Guiomar P, Jackson C, Rorbach J, et al. Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs. Nucleic Acids Res. 2016;44:7804-16 pubmed publisher
|
Santeford A, Wiley L, Park S, Bamba S, Nakamura R, Gdoura A, et al. Impaired autophagy in macrophages promotes inflammatory eye disease. Autophagy. 2016;12:1876-1885 pubmed
|
Thomsen M, Birkelund S, Burkhart A, Stensballe A, Moos T. Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood-brain barrier. J Neurochem. 2017;140:741-754 pubmed publisher
|
Micheva K, Wolman D, Mensh B, Pax E, Buchanan J, Smith S, et al. A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons. elife. 2016;5: pubmed publisher
|
Eminaga S, Teekakirikul P, Seidman C, Seidman J. Detection of Cell Proliferation Markers by Immunofluorescence Staining and Microscopy Imaging in Paraffin-Embedded Tissue Sections. Curr Protoc Mol Biol. 2016;115:14.25.1-14.25.14 pubmed publisher
|
Takanari H, Bourgonje V, Fontes M, Raaijmakers A, Driessen H, Jansen J, et al. Calmodulin/CaMKII inhibition improves intercellular communication and impulse propagation in the heart and is antiarrhythmic under conditions when fibrosis is absent. Cardiovasc Res. 2016;111:410-21 pubmed publisher
|
Park K, Luo X, Mooney S, Yungher B, Belin S, Wang C, et al. Retinal ganglion cell survival and axon regeneration after optic nerve injury in naked mole-rats. J Comp Neurol. 2017;525:380-388 pubmed publisher
|
Lin C, Potter C. Editing Transgenic DNA Components by Inducible Gene Replacement in Drosophila melanogaster. Genetics. 2016;203:1613-28 pubmed publisher
|
Farkas J, Freitas P, Bryant D, Whited J, Monaghan J. Neuregulin-1 signaling is essential for nerve-dependent axolotl limb regeneration. Development. 2016;143:2724-31 pubmed publisher
|
Arbore G, West E, Spolski R, Robertson A, Klos A, Rheinheimer C, et al. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⺠T cells. Science. 2016;352:aad1210 pubmed publisher
|
Stiff M, Haigler C. Cotton fiber tips have diverse morphologies and show evidence of apical cell wall synthesis. Sci Rep. 2016;6:27883 pubmed publisher
|
Priego N, Arechederra M, Sequera C, Bragado P, Vázquez Carballo A, Gutierrez Uzquiza A, et al. C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38? activation, while it impairs tumor growth through p38?-independent mechanisms. Oncotarget. 2016;7:45060-45078 pubmed publisher
|
Ryan T, Schmidt C, Green T, Spangenburg E, Neufer P, McClung J. Targeted Expression of Catalase to Mitochondria Protects Against Ischemic Myopathy in High-Fat Diet-Fed Mice. Diabetes. 2016;65:2553-68 pubmed publisher
|
Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher
|
Ryan T, Schmidt C, Alleman R, Tsang A, Green T, Neufer P, et al. Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol. 2016;97:191-6 pubmed publisher
|
Penterling C, Drexler G, Böhland C, Stamp R, Wilke C, Braselmann H, et al. Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair. PLoS ONE. 2016;11:e0156599 pubmed publisher
|
Bai H, Zhu Q, Surcel A, Luo T, Ren Y, Guan B, et al. Yes-associated protein impacts adherens junction assembly through regulating actin cytoskeleton organization. Am J Physiol Gastrointest Liver Physiol. 2016;311:G396-411 pubmed publisher
|
Turner K, Hawkins T, Yáñez J, Anadón R, Wilson S, Folgueira M. Afferent Connectivity of the Zebrafish Habenulae. Front Neural Circuits. 2016;10:30 pubmed publisher
|
Igarashi H, Koizumi K, Kaneko R, Ikeda K, Egawa R, Yanagawa Y, et al. A Novel Reporter Rat Strain That Conditionally Expresses the Bright Red Fluorescent Protein tdTomato. PLoS ONE. 2016;11:e0155687 pubmed publisher
|
Kobayashi Y, Yoshida S, Zhou Y, Nakama T, Ishikawa K, Arima M, et al. Tenascin-C promotes angiogenesis in fibrovascular membranes in eyes with proliferative diabetic retinopathy. Mol Vis. 2016;22:436-45 pubmed
|
Wei Z, Yuan Y, Jaouen F, Ma M, Hao C, Zhang Z, et al. SLC35D3 increases autophagic activity in midbrain dopaminergic neurons by enhancing BECN1-ATG14-PIK3C3 complex formation. Autophagy. 2016;12:1168-79 pubmed publisher
|
Shi H, Drummond C, Fan X, Haller S, Liu J, Malhotra D, et al. Hiding inside? Intracellular expression of non-glycosylated c-kit protein in cardiac progenitor cells. Stem Cell Res. 2016;16:795-806 pubmed publisher
|
Varela C, Weiss S, Meyer R, Halassa M, Biedenkapp J, Wilson M, et al. Tracking the Time-Dependent Role of the Hippocampus in Memory Recall Using DREADDs. PLoS ONE. 2016;11:e0154374 pubmed publisher
|
Mohr M, Garcia F, Doncarlos L, Sisk C. Neurons and Glial Cells Are Added to the Female Rat Anteroventral Periventricular Nucleus During Puberty. Endocrinology. 2016;157:2393-402 pubmed publisher
|
Du L, Liu P. CXCL12/CXCR4 axis regulates neovascularization and lymphangiogenesis in sutured corneas in mice. Mol Med Rep. 2016;13:4987-94 pubmed publisher
|
Yamashita D, Moriuchi T, Osumi T, Hirose F. Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α. J Biol Chem. 2016;291:11619-34 pubmed publisher
|
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
|
Vandenplas S, Willems M, Witten P, Hansen T, Fjelldal P, Huysseune A. Epithelial Label-Retaining Cells Are Absent during Tooth Cycling in Salmo salar and Polypterus senegalus. PLoS ONE. 2016;11:e0152870 pubmed publisher
|
Su K, Cao J, Tang Z, Dai S, He Y, Sampson S, et al. HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth. Nat Cell Biol. 2016;18:527-39 pubmed publisher
|
Ojeda Fernandez L, Recio Poveda L, Aristorena M, Lastres P, Blanco F, Sanz Rodriguez F, et al. Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response. PLoS Genet. 2016;12:e1005935 pubmed publisher
|
Schaufler V, Czichos Medda H, Hirschfeld Warnecken V, Neubauer S, Rechenmacher F, Medda R, et al. Selective binding and lateral clustering of ?5?1 and ?v?3 integrins: Unraveling the spatial requirements for cell spreading and focal adhesion assembly. Cell Adh Migr. 2016;10:505-515 pubmed
|
O Rourke J, Bogdanik L, Yáñez A, Lall D, Wolf A, Muhammad A, et al. C9orf72 is required for proper macrophage and microglial function in mice. Science. 2016;351:1324-9 pubmed publisher
|
Goode D, Obier N, Vijayabaskar M, Lie A Ling M, Lilly A, Hannah R, et al. Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation. Dev Cell. 2016;36:572-87 pubmed publisher
|
Moriuchi T, Kuroda M, Kusumoto F, Osumi T, Hirose F. Lamin A reassembly at the end of mitosis is regulated by its SUMO-interacting motif. Exp Cell Res. 2016;342:83-94 pubmed publisher
|
Matsumoto M, Nakamachi T, Watanabe J, Sugiyama K, Ohtaki H, Murai N, et al. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke. J Mol Neurosci. 2016;59:270-9 pubmed publisher
|
Vance M, Llanga T, Bennett W, Woodard K, Murlidharan G, Chungfat N, et al. AAV Gene Therapy for MPS1-associated Corneal Blindness. Sci Rep. 2016;6:22131 pubmed publisher
|
Gonçalves A, Thorsteinsdóttir S, Deries M. Rapid and simple method for in vivo ex utero development of mouse embryo explants. Differentiation. 2016;91:57-67 pubmed publisher
|
Chatterjee G, Sankaranarayanan S, Guin K, Thattikota Y, Padmanabhan S, Siddharthan R, et al. Repeat-Associated Fission Yeast-Like Regional Centromeres in the Ascomycetous Budding Yeast Candida tropicalis. PLoS Genet. 2016;12:e1005839 pubmed publisher
|
Hsu C, Bhandawat V. Organization of descending neurons in Drosophila melanogaster. Sci Rep. 2016;6:20259 pubmed publisher
|
Morganti J, Riparip L, Rosi S. Call Off the Dog(ma): M1/M2 Polarization Is Concurrent following Traumatic Brain Injury. PLoS ONE. 2016;11:e0148001 pubmed publisher
|
Minoura I, Takazaki H, Ayukawa R, Saruta C, Hachikubo Y, Uchimura S, et al. Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin-microtubule interface. Nat Commun. 2016;7:10058 pubmed publisher
|
Loebel D, Plageman T, Tang T, Jones V, Muccioli M, Tam P. Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5:130-9 pubmed publisher
|
Ge Y, Zhang L, Nikolova M, Reva B, Fuchs E. Strand-specific in vivo screen of cancer-associated miRNAs unveils a role for miR-21(∗) in SCC progression. Nat Cell Biol. 2016;18:111-21 pubmed publisher
|
Zhong C, Cui K, Wilhelm C, Hu G, Mao K, Belkaid Y, et al. Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment. Nat Immunol. 2016;17:169-78 pubmed publisher
|
Clark H, Jhingran A, Sun Y, Vareechon C, de Jesus Carrion S, Skaar E, et al. Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection. J Immunol. 2016;196:336-44 pubmed publisher
|
Podlasz P, Jakimiuk A, Chmielewska Krzesinska M, Kasica N, Nowik N, Kaleczyc J. Galanin regulates blood glucose level in the zebrafish: a morphological and functional study. Histochem Cell Biol. 2016;145:105-17 pubmed publisher
|
Murayama M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun. 2015;6:8483 pubmed publisher
|
Pooryasin A, Fiala A. Identified Serotonin-Releasing Neurons Induce Behavioral Quiescence and Suppress Mating in Drosophila. J Neurosci. 2015;35:12792-812 pubmed publisher
|
Taketa D, Nydam M, Langenbacher A, Rodriguez D, Sanders E, De Tomaso A. Molecular evolution and in vitro characterization of Botryllus histocompatibility factor. Immunogenetics. 2015;67:605-23 pubmed publisher
|
Imamura O, Arai M, Dateki M, Ogata T, Uchida R, Tomoda H, et al. Nicotinic acetylcholine receptors mediate donepezil-induced oligodendrocyte differentiation. J Neurochem. 2015;135:1086-98 pubmed publisher
|
Liu W, Wei LaPierre L, Klose A, Dirksen R, Chakkalakal J. Inducible depletion of adult skeletal muscle stem cells impairs the regeneration of neuromuscular junctions. elife. 2015;4: pubmed publisher
|
Moyat M, Mack M, Bouzourene H, Velin D. Role of Inflammatory Monocytes in Vaccine-Induced Reduction of Helicobacter felis Infection. Infect Immun. 2015;83:4217-28 pubmed publisher
|
Hieke N, Löffler A, Kaizuka T, Berleth N, Böhler P, Drießen S, et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy. 2015;11:1471-83 pubmed publisher
|
Engel B, Constantinou P, Sablatura L, Doty N, Carson D, Farach Carson M, et al. Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures. Adv Healthc Mater. 2015;4:1664-74 pubmed publisher
|
Römer C, Engel O, Winek K, Hochmeister S, Zhang T, Royl G, et al. Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke. J Neurosci. 2015;35:7777-94 pubmed publisher
|
Viswanathan S, Williams M, Bloss E, Stasevich T, Speer C, Nern A, et al. High-performance probes for light and electron microscopy. Nat Methods. 2015;12:568-76 pubmed publisher
|
Wan W, Liu Q, Lionakis M, Marino A, Anderson S, Swamydas M, et al. Atypical chemokine receptor 1 deficiency reduces atherogenesis in ApoE-knockout mice. Cardiovasc Res. 2015;106:478-87 pubmed publisher
|
Bennett R, Brody D. Array tomography for the detection of non-dilated, injured axons in traumatic brain injury. J Neurosci Methods. 2015;245:25-36 pubmed publisher
|
Freeman S, Jaumouillé V, Choi K, Hsu B, Wong H, Abraham L, et al. Toll-like receptor ligands sensitize B-cell receptor signalling by reducing actin-dependent spatial confinement of the receptor. Nat Commun. 2015;6:6168 pubmed publisher
|
Nakagawa A, Sullivan K, Xue D. Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway. Nat Struct Mol Biol. 2014;21:1082-90 pubmed publisher
|
Fonseca Pereira D, Arroz Madeira S, Rodrigues Campos M, Barbosa I, Domingues R, Bento T, et al. The neurotrophic factor receptor RET drives haematopoietic stem cell survival and function. Nature. 2014;514:98-101 pubmed publisher
|
Gautron L, Rutkowski J, Burton M, Wei W, Wan Y, Elmquist J. Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen. J Comp Neurol. 2013;521:3741-67 pubmed publisher
|
Nagao K, Kobayashi T, Moro K, Ohyama M, Adachi T, Kitashima D, et al. Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin. Nat Immunol. 2012;13:744-52 pubmed publisher
|
Beutner C, Roy K, Linnartz B, Napoli I, Neumann H. Generation of microglial cells from mouse embryonic stem cells. Nat Protoc. 2010;5:1481-94 pubmed publisher
|
Hsu J, McKeon R, Goussev S, Werb Z, Lee J, Trivedi A, et al. Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury. J Neurosci. 2006;26:9841-50 pubmed
|