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ELISA/assay

Multispecies MAPK Family Activation InstantOne ELISA Kit

85-86195-11

96 Tests

896 USD

85-86195-11

ELISA Kits

JNK1/JNK2/JNK3/ERK1/2/p38 MAPK alpha

Multispecies MAPK Family Activation InstantOne ELISA Kit

MAP kinases play a significant role in many biological processes, including cell adhesion and spreading, cell differentiation and apoptosis. MAPKBP-1 (mitogen-activated protein kinase binding protein 1), also known as JNKBP-1, is a 1,514 amino acid protein that contains twelve WD repeats. Induced by TRAF2 (TNF receptor-associated factor 2) and Tak1 (TGF- -activated kinase 1), MAPKBP-1 is thought to act an adaptor protein for NF B (nuclear factor -B) activation. MAPKBP-1 interacts with JNK3 and may promote TRAF2 polyubiquitination. MAPKBP-1 exists as six alternatively spliced variants and is encoded by a gene located on human chromosome 15. Human chromosome 15 houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

MAPK

896 USD

96 Tests

Human

ELISA

2-8 C

Cell Lysate, 20 µL

1 hr 20 min

This product is for research use only.