CD11b Monoclonal Antibody (M1/70), eVolve 605, eBioscience™ | Invitrogen 83-0112-42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CD11b Monoclonal Antibody (M1/70), eVolve 605, eBioscience™

catalog :

83-0112-42

quantity :

100Tests

price :

US 299.00

clonality :

monoclonal

host :

rat

conjugate :

eVolve605

clone name :

M1/70

reactivity :

mouse

application :

flow cytometry

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...	Saha S, Aranda E, Hayakawa Y, Bhanja P, Atay S, Brodin N, et al. Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury. Nat Commun. 2016;7:13096 pubmed publisher
	Zhang Y, McCormick L, Desai S, Wu C, Gilliam A. Murine sclerodermatous graft-versus-host disease, a model for human scleroderma: cutaneous cytokines, chemokines, and immune cell activation. J Immunol. 2002;168:3088-98 pubmed
	Dembic Z, Schenck K, Bogen B. Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells. Proc Natl Acad Sci U S A. 2000;97:2697-702 pubmed
	Ault K, Springer T. Cross-reaction of a rat-anti-mouse phagocyte-specific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J Immunol. 1981;126:359-64 pubmed

product information

Product Type :

Antibody

Product Name :

CD11b Monoclonal Antibody (M1/70), eVolve 605, eBioscience™

Catalog # :

83-0112-42

Quantity :

100Tests

Price :

US 299.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 5 µL/test

Species :

Mouse

Clone :

M1/70

Isotype :

IgG2b, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement coated particles. It is identical to CR3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the RGD peptide in C3b. CD11b is also a receptor for fibrinogen, factor X, and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. The Mac1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, and blood monocytes. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 µL/test

Aliases :

CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A, SLEB6, Integrin alpha M