IgM Monoclonal Antibody (II/41), Super Bright 780, eBioscience™ | Invitrogen 78-5790-82 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IgM Monoclonal Antibody (II/41), Super Bright 780, eBioscience™

catalog :

78-5790-82

quantity :

100 µg

price :

US 329.00

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

II/41

reactivity :

mouse

application :

flow cytometry

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:200; loading ...; fig 5b	Xu A, Barbosa R, Calado D. Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover. elife. 2020;9: pubmed publisher
flow cytometry; mouse; 1:120; loading ...; fig 1a	Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed publisher
flow cytometry; mouse; loading ...; fig 5i	Moffett H, Harms C, Fitzpatrick K, Tooley M, Boonyaratanakornkit J, Taylor J. B cells engineered to express pathogen-specific antibodies protect against infection. Sci Immunol. 2019;4: pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig s4b	Yeh C, Nojima T, Kuraoka M, Kelsoe G. Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density. Nat Commun. 2018;9:928 pubmed publisher

product information

Product Type :

Antibody

Product Name :

IgM Monoclonal Antibody (II/41), Super Bright 780, eBioscience™

Catalog # :

78-5790-82

Quantity :

100 µg

Price :

US 329.00

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rat

Reactivity :

Mouse

Applications :

Flow Cytometry: 1.0 µg/test

Species :

Mouse

Clone :

II/41

Isotype :

IgG2a, kappa

Storage :

4° C, store in dark, DO NOT FREEZE!

Description :

IgM (Immunoglobulin M) is expressed intracellularly during the early stages of B lymphopoiesis, and then on the surface of more mature B cells in the bone marrow and peripheral B cells. The isotype of a primary antibody and its application can result in background staining. Primary antibody background noise can be caused by binding to Fc receptors on target cells; by non-specific interactions with cellular proteins, carbohydrates, and lipids; or by cell autofluorescence. Isotype control antibodies can act as negative controls to help differentiate non-specific background signal from specific antibody signal because they have no relevant specificity to a target antigen. While isotype controls are most commonly used in flow cytometry, they are also useful in other applications such as chromatin immunoprecipitation (ChIP), immunohistochemistry, and gel shifts. Isotype controls should match with the primary antibody species and isotype so that the level of specific staining by the primary antibody may be accurately determined. If using directly labeled primary antibodies, the isotype control works best if conjugated with the same label as the test antibody.

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1.0 µg/test

Aliases :

AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH

more info or order :

Invitrogen product webpage