MECP2 Recombinant Superclonal Antibody (2HCLC) | Invitrogen 711065 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MECP2 Recombinant Superclonal Antibody (2HCLC)

catalog :

711065

quantity :

100 ug

price :

US 414.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

2HCLC

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 1

Reference
Bardóczi Z, Pál B, Koszeghy A, Wilheim T, Watanabe M, Zaborszky L, et al. Glycinergic Input to the Mouse Basal Forebrain Cholinergic Neurons. J Neurosci. 2017;37:9534-9549 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MECP2 Recombinant Superclonal Antibody (2HCLC)

Catalog # :

711065

Quantity :

100 ug

Price :

US 414.00

Clonality :

Recombinant Superclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 2 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse

Clone :

2HCLC

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Immunogen :

Peptides corresponding to Human MECP2 (aa 17-34, 464-475)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10