Phospho-4EBP1 (Thr46) Recombinant Superclonal Antibody (19HCLC)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-4EBP1 (Thr46) Recombinant Superclonal Antibody (19HCLC)

catalog :

710323

quantity :

100 ug

price :

US 520.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

19HCLC

reactivity :

human

application :

western blot, immunocytochemistry

citations: 1

Reference
Moro A, Driscoll T, Boraas L, Armero W, Kasper D, Baeyens N, et al. MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis. Nat Cell Biol. 2019;21:348-358 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-4EBP1 (Thr46) Recombinant Superclonal Antibody (19HCLC)

Catalog # :

710323

Quantity :

100 ug

Price :

US 520.00

Clonality :

Recombinant Superclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human

Clone :

19HCLC

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Immunogen :

Phosopeptide corresponding to amino acids 41-50 of human 4EBP1 [pT46]

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1