Pannexin 1 Recombinant Polyclonal Antibody (11HCLC) | Invitrogen 710184 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Pannexin 1 Recombinant Polyclonal Antibody (11HCLC)

catalog :

710184

quantity :

100 µg

price :

US 430.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

11HCLC

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 5	Thuringer D, Berthenet K, Cronier L, Solary E, Garrido C. Primary tumor- and metastasis-derived colon cancer cells differently modulate connexin expression and function in human capillary endothelial cells. Oncotarget. 2015;6:28800-15 pubmed publisher
	Jalaleddine N, El Hajjar L, Dakik H, Shaito A, Saliba J, Safi R, et al. Pannexin1 Is Associated with Enhanced Epithelial-To-Mesenchymal Transition in Human Patient Breast Cancer Tissues and in Breast Cancer Cell Lines. Cancers (Basel). 2019;11: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Pannexin 1 Recombinant Polyclonal Antibody (11HCLC)

Catalog # :

710184

Quantity :

100 µg

Price :

US 430.00

Clonality :

Recombinant Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1-3 µg/mL, Western Blot: 1-3 µg/mL

Species :

Human

Clone :

11HCLC

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Immunogen :

Peptide corresponding to amino acids 347–360 of human pannexin 1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-3 µg/mL, Western Blot: 1-3 µg/mL

Aliases :

AI847747; innexin; MRS1; Pannexin 1; pannexin-1; Panx1; px1; UNQ2529; UNQ2529/PRO6028

more info or order :

Invitrogen product webpage