IL-10 Recombinant Superclonal Antibody (1HCLC) | Invitrogen 710170 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IL-10 Recombinant Superclonal Antibody (1HCLC)

catalog :

710170

quantity :

100 ug

price :

US 414.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

1HCLC

reactivity :

mouse

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

IL-10 Recombinant Superclonal Antibody (1HCLC)

Catalog # :

710170

Quantity :

100 ug

Price :

US 414.00

Clonality :

Recombinant Superclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Mouse

Applications :

Immunocytochemistry: 1:100, Western Blot: 2-5 ug/mL

Species :

Mouse

Clone :

1HCLC

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

Immunogen :

Recombinant protein corresponding to amino acids 19–178 of mouse interleukin 10

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Western Blot: 2-5 ug/mL

Aliases :

CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF