GSK3B Recombinant Superclonal Antibody (1HCLC) | Invitrogen 710132 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GSK3B Recombinant Superclonal Antibody (1HCLC)

catalog :

710132

quantity :

100 ug

price :

US 496.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

1HCLC

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 1

Reference
Wang R, Zhang Z, Kumar M, Xu G, Zhang M. Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K/AKT/GSK-3β pathway. Drug Des Devel Ther. 2019;13:501-512 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GSK3B Recombinant Superclonal Antibody (1HCLC)

Catalog # :

710132

Quantity :

100 ug

Price :

US 496.00

Clonality :

Recombinant Superclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate

Applications :

Immunocytochemistry: 5 ug/mL, Western Blot: 0.5-1 ug/mL

Species :

Human, Mouse, Non-human primate

Clone :

1HCLC

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.

Immunogen :

Recombinant protein corresponding to amino acids 317–433 of human GSK3 beta

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Western Blot: 0.5-1 ug/mL

Aliases :

7330414F15Rik; 8430431H08Rik; C86142; EC 2.7.11.26; FA; Factor A; fb68h05; fk80d11; glycogen synthase kinase 3; glycogen synthase kinase 3 beta; glycogen synthase kinase 3 beta L homeolog; glycogen synthase kinase 3 beta variant 1; glycogen synthase kinase 3 beta variant 2; glycogen synthase kinase 3 beta variant 3; glycogen synthase kinase 3 beta variant 4; glycogen synthase kinase 3 beta variant 5; glycogen synthase kinase 3 beta, genome duplicate a; glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta splice variant X1; glycogen synthase kinase-3 beta splice variant X2; glycogen synthase kinase-3 beta splice variant X3; GSK 3 beta; GSK 3B; gsk3; GSK-3; GSK3 beta; GSK-3 beta; GSK-3 beta GSK3B; GSK-3[b]; Gsk3b; GSK-3b; gsk3b.L; gsk3ba; gsk3beta; GSK-3beta; gsk3-beta; GSK3beta isoform; intracellular kinase; pp37; serine/threonine-protein kinase GSK3B; wu:fb68h05; wu:fk80d11; XELAEV_180112401mg; xgsk-3; Xgsk-3 protein