This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IL-31 Recombinant Superclonal Antibody (15HCLC)
catalog :
710107
quantity :
100 ug
price :
US 414.00
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
15HCLC
reactivity :
human
application :
western blot
product information
Product Type :
Antibody
Product Name :
IL-31 Recombinant Superclonal Antibody (15HCLC)
Catalog # :
710107
Quantity :
100 ug
Price :
US 414.00
Clonality :
Recombinant Superclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Western Blot: 0.5-2 ug/mL
Species :
Human
Clone :
15HCLC
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.
Immunogen :
Recombinant protein corresponding to amino acids 24–164 of human Interleukin 31
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.5-2 ug/mL
Aliases :
1700013B14Rik; IL31; IL-31; ILN; Interleukin; interleukin 31; interleukin-31
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA