Phospho-INSR (Tyr1158) Recombinant Superclonal Antibody (8HCLC)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-INSR (Tyr1158) Recombinant Superclonal Antibody (8HCLC)

catalog :

710101

quantity :

100 ug

price :

US 500.00

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

8HCLC

The same clone is also sold as:

Abcam: ab277763

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Peng Y, Tran N, Krishnaswamy A, Kostadinov D, Martersteck E, Sanes J. Satb1 Regulates Contactin 5 to Pattern Dendrites of a Mammalian Retinal Ganglion Cell. Neuron. 2017;95:869-883.e6 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-INSR (Tyr1158) Recombinant Superclonal Antibody (8HCLC)

Catalog # :

710101

Quantity :

100 ug

Price :

US 500.00

Clonality :

Recombinant Superclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 2-3 ug/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1-5 ug/mL

Species :

Human

Clone :

8HCLC

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.

Immunogen :

Phosphopeptide corresponding to amino acids 1153–1162 of human Insulin receptor

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2-3 ug/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 1-5 ug/mL

Aliases :

4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B