product summary
Loading...
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Annexin A1 Polyclonal Antibody
catalog :
71-3400
quantity :
100 µL
price :
US 500.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation, immunocytochemistry knockout validation
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; human; 1:100; fig 2
  • western blot knockout validation; human; 1:10,000; fig 1
Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100; fig s3a
de Jong R, Paulin N, Lemnitzer P, Viola J, Winter C, Ferraro B, et al. Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37:312-315 pubmed publisher
  • western blot; human; loading ...
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  • western blot; human; 1:10,000; loading ...; fig 2
Bizzarro V, Belvedere R, Migliaro V, Romano E, Parente L, Petrella A. Hypoxia regulates ANXA1 expression to support prostate cancer cell invasion and aggressiveness. Cell Adh Migr. 2017;11:247-260 pubmed publisher
  • immunocytochemistry; mouse
  • western blot; mouse; loading ...; fig 2a
de Torre Minguela C, Barberà Cremades M, Gómez A, Martín Sánchez F, Pelegrín P. Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep. 2016;6:22586 pubmed publisher
  • western blot; human; fig 2g
Colangelo T, Polcaro G, Ziccardi P, Pucci B, Muccillo L, Galgani M, et al. Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer. Cell Death Dis. 2016;7:e2120 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
  • western blot; human; 1:1000; fig 3
Fournier N, Tardivel S, Benoist J, Vedie B, Rousseau Ralliard D, Nowak M, et al. Eicosapentaenoic acid membrane incorporation impairs ABCA1-dependent cholesterol efflux via a protein kinase A signaling pathway in primary human macrophages. Biochim Biophys Acta. 2016;1861:331-41 pubmed publisher
de Klerk E, Xiao Y, Emfinger C, Keller M, Berrios D, Loconte V, et al. Loss of ZNF148 enhances insulin secretion in human pancreatic β cells. JCI Insight. 2023;8: pubmed publisher
Sandri S, Hebeda C, Broering M, de Paula Silva M, Moredo L, de Barros E Silva M, et al. Role of Annexin A1 Secreted by Neutrophils in Melanoma Metastasis. Cells. 2023;12: pubmed publisher
Galv xe3 o I, Mastrippolito D, Talamini L, Aganetti M, ROCHA V, Verdot C, et al. The Therapeutic Effect of Phosphopeptide P140 Attenuates Inflammation Induced by Uric Acid Crystals in Gout Arthritis Mouse Model. Cells. 2022;11: pubmed publisher
Fungbun N, Sasaki H, Terashima R, Murata T, Chiba S, Kurusu S, et al. Changes in the expression of annexin A1 in the anterior pituitary gland after ovariectomy in rats. J Vet Med Sci. 2022;84:1288-1291 pubmed publisher
Vecchi L, Mota S, Z xf3 ia M, Martins I, de Souza J, Santos T, et al. Interleukin-6 Signaling in Triple Negative Breast Cancer Cells Elicits the Annexin A1/Formyl Peptide Receptor 1 Axis and Affects the Tumor Microenvironment. Cells. 2022;11: pubmed publisher
Zhang Z, Ma Q, Velagapudi R, Barclay W, Rodriguiz R, Wetsel W, et al. Annexin-A1 Tripeptide Attenuates Surgery-Induced Neuroinflammation and Memory Deficits Through Regulation the NLRP3 Inflammasome. Front Immunol. 2022;13:856254 pubmed publisher
Delorme S, Privat M, Sonnier N, Rouanet J, Witkowski T, Kossai M, et al. New insight into the role of ANXA1 in melanoma progression: involvement of stromal expression in dissemination. Am J Cancer Res. 2021;11:1600-1615 pubmed
Giese I, Schilloks M, Degroote R, Weigand M, Renner S, Wolf E, et al. Chronic Hyperglycemia Drives Functional Impairment of Lymphocytes in Diabetic INS C94Y Transgenic Pigs. Front Immunol. 2020;11:607473 pubmed publisher
Silva Oliveira R, Pereira F, Petronilho S, Martins A, Lameirinhas A, Constâncio V, et al. Clinical Significance of ARID1A and ANXA1 in HER-2 Positive Breast Cancer. J Clin Med. 2020;9: pubmed publisher
Vallecillo Zúniga M, Rathgeber M, Poulson P, Hayes S, Luddington J, Gill H, et al. Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models. PLoS ONE. 2020;15:e0238441 pubmed publisher
Hebeda C, Sandri S, Benis C, Paula Silva M, Loiola R, Reutelingsperger C, et al. Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst. Cells. 2020;9: pubmed publisher
McArthur S, Juban G, Gobbetti T, Desgeorges T, Theret M, Gondin J, et al. Annexin A1 drives macrophage skewing to accelerate muscle regeneration through AMPK activation. J Clin Invest. 2020;130:1156-1167 pubmed publisher
Zub E, Canet G, Garbelli R, Blaquière M, Rossini L, Pastori C, et al. The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy. FASEB J. 2019;33:13998-14009 pubmed publisher
Colamatteo A, Maggioli E, Azevedo Loiola R, Hamid Sheikh M, Cali G, Bruzzese D, et al. Reduced Annexin A1 Expression Associates with Disease Severity and Inflammation in Multiple Sclerosis Patients. J Immunol. 2019;203:1753-1765 pubmed publisher
Ding Y, Flores J, Klebe D, Li P, McBride D, Tang J, et al. Annexin A1 attenuates neuroinflammation through FPR2/p38/COX-2 pathway after intracerebral hemorrhage in male mice. J Neurosci Res. 2020;98:168-178 pubmed publisher
Rubinstein M, Baik J, Lagana S, Han R, Raab W, Sahoo D, et al. Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β-catenin modulator Annexin A1. EMBO Rep. 2019;20: pubmed publisher
Shrestha A, Bettini M, Menon R, Gopal V, Huang S, Edwards D, et al. Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice. Am J Physiol Lung Cell Mol Physiol. 2019;316:L229-L244 pubmed publisher
Vidotto A, Polachini G, de Paula Silva M, Oliani S, Henrique T, López R, et al. Differentially expressed proteins in positive versus negative HNSCC lymph nodes. BMC Med Genomics. 2018;11:73 pubmed publisher
Lima K, Vago J, Caux T, Negreiros Lima G, Sugimoto M, Tavares L, et al. The resolution of acute inflammation induced by cyclic AMP is dependent on annexin A1. J Biol Chem. 2017;292:13758-13773 pubmed publisher
Berns K, Sonnenblick A, Gennissen A, Brohée S, Hijmans E, Evers B, et al. Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance. Clin Cancer Res. 2016;22:5238-5248 pubmed
Leoni G, Neumann P, Kamaly N, Quirós M, Nishio H, Jones H, et al. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest. 2015;125:1215-27 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Annexin A1 Polyclonal Antibody
Catalog # :
71-3400
Quantity :
100 µL
Price :
US 500.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: 1:500-1:50,000, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:100-1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20°C
Description :
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
Immunogen :
Full-length human recombinant Annexin I protein purified from yeast.
Format :
Liquid
Applications w/Dilutions :
ELISA: 1:500-1:50,000, Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:100-1:1,000
Aliases :
ANAX1; Annexin 1 (p35) (Lipocortin 1); annexin A1; Annexin I; annexin I (lipocortin I); annexin-1; ANX1; Anx-1; Anxa1; Anx-A1; C430014K04Rik; Calpactin II; calpactin-2; Chromobindin-9; lipocortin 1; lipocortin I; LPC1; Lpc-1; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA