| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 9b
- western blot; human; loading ...; fig 9i
| Tang X, Wang W, Hong G, Duan C, Zhu S, Tian Y, et al. Gut microbiota-mediated lysophosphatidylcholine generation promotes colitis in intestinal epithelium-specific Fut2 deficiency. J Biomed Sci. 2021;28:20 pubmed publisher |
- western blot; mouse; fig 4f
| Peroutka R, Buzza M, Mukhopadhyay S, Johnson T, Driesbaugh K, Antalis T. Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis. PLoS ONE. 2020;15:e0234407 pubmed publisher |
- western blot; mouse; 1:2000; loading ...; fig 6d
| Xing T, Benderman L, Sabu S, Parker J, Yang J, Lu Q, et al. Tight Junction Protein Claudin-7 Is Essential for Intestinal Epithelial Stem Cell Self-Renewal and Differentiation. Cell Mol Gastroenterol Hepatol. 2020;9:641-659 pubmed publisher |
- western blot; human; loading ...; fig s2b
| Wang R, Yu R, Zhu C, Lin H, Lu X, Wang H. Tubulin detyrosination promotes human trophoblast syncytium formation. J Mol Cell Biol. 2019;: pubmed publisher |
- western blot; rat; fig 2a
| Rempe R, Hartz A, Soldner E, Sokola B, Alluri S, Abner E, et al. Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy. J Neurosci. 2018;38:4301-4315 pubmed publisher |
- western blot; mouse; loading ...; fig s2g
| Yang A, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, et al. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017;127:2829-2841 pubmed publisher |
- western blot; human; 1:1000; fig 5g
| Benedicto I, Lehmann G, Ginsberg M, Nolan D, Bareja R, Elemento O, et al. Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nat Commun. 2017;8:15374 pubmed publisher |
- immunocytochemistry; dogs; 1:200; loading ...; fig 7d
- western blot; dogs; loading ...; fig 7e
| Lapierre L, Manning E, Mitchell K, Caldwell C, Goldenring J. Interaction of phosphorylated Rab11-FIP2 with Eps15 regulates apical junction composition. Mol Biol Cell. 2017;28:1088-1100 pubmed publisher |
- western blot; mouse; loading ...; fig 4f
| Tung K, Harakal J, Qiao H, Rival C, Li J, Paul A, et al. Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance. J Clin Invest. 2017;127:1046-1060 pubmed publisher |
- immunocytochemistry; dogs; loading ...; fig 5a
| Kraya R, Komin A, Searson P. On Chip Bioelectric Impedance Spectroscopy Reveals the Effect of P-Glycoprotein Efflux Pumps on the Paracellular Impedance of Tight Junctions at the Blood-Brain Barrier. IEEE Trans Nanobioscience. 2016;15:697-703 pubmed publisher |
- immunocytochemistry; dogs; 1:50; loading ...; fig 7a
| Capra J, Eskelinen S. MDCK cells are capable of water secretion and reabsorption in response to changes in the ionic environment. Can J Physiol Pharmacol. 2017;95:72-83 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 7c
| Chehaibi K, le Maire L, Bradoni S, Escolà J, Blanco Vaca F, Slimane M. Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury. Transl Res. 2017;182:27-48 pubmed publisher |
- western blot; rat; 1:1000; loading ...; fig 5a
| Keppner A, Malsure S, Nobile A, Auberson M, Bonny O, Hummler E. Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis. Inflamm Bowel Dis. 2016;22:2824-2839 pubmed |
- immunocytochemistry; rat; 1:100; loading ...; fig 3c
| Mendonça M, Soares E, de Jesus M, Ceragioli H, Batista Ã, Nyúl Tóth Ã, et al. PEGylation of Reduced Graphene Oxide Induces Toxicity in Cells of the Blood-Brain Barrier: An in Vitro and in Vivo Study. Mol Pharm. 2016;13:3913-3924 pubmed |
- immunohistochemistry - paraffin section; dogs; 1:200; loading ...; fig 4a
- western blot; dogs; 1:1000; loading ...; fig 3d
| Ahn C, Shin D, Lee D, Kang S, Seok J, Kang H, et al. Expression of claudins, occludin, junction adhesion molecule A and zona occludens 1 in canine organs. Mol Med Rep. 2016;14:3697-703 pubmed publisher |
- immunohistochemistry; mouse; 7 ug/ml; loading ...; tbl s5
- western blot; mouse; 3 ug/ml; loading ...; tbl s5
| de Sousa Rodrigues M, Bekhbat M, Houser M, Chang J, Walker D, Jones D, et al. Chronic psychological stress and high-fat high-fructose diet disrupt metabolic and inflammatory gene networks in the brain, liver, and gut and promote behavioral deficits in mice. Brain Behav Immun. 2017;59:158-172 pubmed publisher |
- western blot; rat; 1:250; loading ...; tbl 1
| Li N, Lee W, Cheng C. Overexpression of plastin 3 in Sertoli cells disrupts actin microfilament bundle homeostasis and perturbs the tight junction barrier. Spermatogenesis. 2016;6:e1206353 pubmed publisher |
- western blot; mouse; 1:400; loading ...; fig 4l
| Wardill H, Bowen J, Van Sebille Y, Secombe K, Coller J, Ball I, et al. TLR4-Dependent Claudin-1 Internalization and Secretagogue-Mediated Chloride Secretion Regulate Irinotecan-Induced Diarrhea. Mol Cancer Ther. 2016;15:2767-2779 pubmed |
- western blot; rat; 1:1000; fig 1
- western blot; human; 1:1000; fig 1
- western blot; mouse; 1:1000; fig 1
| Stammler A, Lüftner B, Kliesch S, Weidner W, Bergmann M, Middendorff R, et al. Highly Conserved Testicular Localization of Claudin-11 in Normal and Impaired Spermatogenesis. PLoS ONE. 2016;11:e0160349 pubmed publisher |
- western blot; rat; 1:250; fig 2
| Li N, Mruk D, Chen H, Wong C, Lee W, Cheng C. Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43. Sci Rep. 2016;6:29667 pubmed publisher |
- western blot; rat; 1:250; fig 5
| Gao Y, Lui W, Lee W, Cheng C. Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells. Sci Rep. 2016;6:28589 pubmed publisher |
- immunohistochemistry; mouse; fig 4
| Lee S, Kim H, Kim K, Lee H, Lee S, Lee D. Arhgap17, a RhoGTPase activating protein, regulates mucosal and epithelial barrier function in the mouse colon. Sci Rep. 2016;6:26923 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 3
- immunohistochemistry - paraffin section; human; fig 3
| Lehner C, Gehwolf R, Ek J, Korntner S, Bauer H, Bauer H, et al. The blood-tendon barrier: identification and characterisation of a novel tissue barrier in tendon blood vessels. Eur Cell Mater. 2016;31:296-311 pubmed |
- immunocytochemistry; rat; 1:100; fig 4
- western blot; rat; 1:500; fig 2
| Xu S, Xue X, You K, Fu J. Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown. Respir Res. 2016;17:50 pubmed publisher |
- immunocytochemistry; human; fig 2
- western blot; human; fig 2
| Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed publisher |
- immunohistochemistry; mouse; fig s6
| Vorvis C, Hatziapostolou M, Mahurkar Joshi S, Koutsioumpa M, Williams J, Donahue T, et al. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. Am J Physiol Gastrointest Liver Physiol. 2016;310:G1124-37 pubmed publisher |
- western blot; human; 1:1000; fig 3
- western blot; pigs ; 1:1000; fig 3
| Inada M, Izawa G, Kobayashi W, Ozawa M. 293 cells express both epithelial as well as mesenchymal cell adhesion molecules. Int J Mol Med. 2016;37:1521-7 pubmed publisher |
- western blot; rat; 1:1000; fig 2
| Yang C, Demars K, Hawkins K, Candelario Jalil E. Adropin reduces paracellular permeability of rat brain endothelial cells exposed to ischemia-like conditions. Peptides. 2016;81:29-37 pubmed publisher |
- western blot; rat; 1:250; fig 3
| Chen H, Mruk D, Lee W, Cheng C. Planar Cell Polarity (PCP) Protein Vangl2 Regulates Ectoplasmic Specialization Dynamics via Its Effects on Actin Microfilaments in the Testes of Male Rats. Endocrinology. 2016;157:2140-59 pubmed publisher |
- immunohistochemistry - paraffin section; human; fig 2
| Kacem M, Agili F, Tounsi H, Zribi H, Zaraa I, Mokni M, et al. Immunohistological study of tight junction protein expression in mal de Meleda. Ultrastruct Pathol. 2016;40:176-80 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig s2
| Ji X, Liu Y, Hurd R, Wang J, Fitzmaurice B, Nishina P, et al. Retinal Pigment Epithelium Atrophy 1 (rpea1): A New Mouse Model With Retinal Detachment Caused by a Disruption of Protein Kinase C, θ. Invest Ophthalmol Vis Sci. 2016;57:877-88 pubmed publisher |
- immunocytochemistry; mouse; 1:1000; fig 1
| Strazielle N, Creidy R, Malcus C, Boucraut J, Ghersi Egea J. T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium. PLoS ONE. 2016;11:e0150945 pubmed publisher |
- western blot; human; fig 6
| Ibrahim A, Mander S, Hussein K, Elsherbiny N, Smith S, Al Shabrawey M, et al. Hyperhomocysteinemia disrupts retinal pigment epithelial structure and function with features of age-related macular degeneration. Oncotarget. 2016;7:8532-45 pubmed publisher |
- western blot; dogs; fig 3
- western blot; mouse; fig 3
| Villarroel Espíndola F, Tapia C, González Stegmaier R, Concha I, Slebe J. Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells. J Cell Physiol. 2016;231:2142-52 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 3
| Miquel S, MartÃn R, Lashermes A, Gillet M, Meleine M, Gelot A, et al. Anti-nociceptive effect of Faecalibacterium prausnitzii in non-inflammatory IBS-like models. Sci Rep. 2016;6:19399 pubmed publisher |
- immunohistochemistry - frozen section; rat; 1:50; tbl 2
| Li N, Mruk D, Mok K, Li M, Wong C, Lee W, et al. Connexin 43 reboots meiosis and reseals blood-testis barrier following toxicant-mediated aspermatogenesis and barrier disruption. FASEB J. 2016;30:1436-52 pubmed publisher |
- immunohistochemistry - paraffin section; dogs; 1:600; fig 1
| Kim H, Cronin M, Ahrens K, Papastavros V, Santoro D, Marsella R. A comparative study of epidermal tight junction proteins in a dog model of atopic dermatitis. Vet Dermatol. 2016;27:40-e11 pubmed publisher |
- western blot; bovine; fig 3
| Arévalo Turrubiarte M, Perruchot M, Finot L, Mayeur F, Dessauge F. Phenotypic and functional characterization of two bovine mammary epithelial cell lines in 2D and 3D models. Am J Physiol Cell Physiol. 2016;310:C348-56 pubmed publisher |
- immunocytochemistry; rat; 2.5 ug/ml; fig 4
- western blot; rat; 1:125; fig 3
| McCabe M, Foo C, Dinger M, Smooker P, Stanton P. Claudin-11 and occludin are major contributors to Sertoli cell tight junction function, in vitro. Asian J Androl. 2016;18:620-6 pubmed publisher |
- western blot; human; fig 1c
| Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed publisher |
- immunocytochemistry; dogs
| Janosevic D, Axis J, Bacallao R, Amsler K. Occludin Content Modulates Hydrogen Peroxide-Induced Increase in Renal Epithelial Paracellular Permeability. J Cell Biochem. 2016;117:769-79 pubmed publisher |
- western blot; chicken; 1:1000
| Liu S, Zhao J, Fan X, Liu G, Jiao H, Wang X, et al. Rapamycin, a specific inhibitor of the target of rapamycin complex 1, disrupts intestinal barrier integrity in broiler chicks. J Anim Physiol Anim Nutr (Berl). 2016;100:323-30 pubmed publisher |
- immunocytochemistry; mouse; 5 ug/ml
- western blot; mouse; 2 ug/ml
| Fernandes S, Salta S, Bravo J, Silva A, Summavielle T. Acetyl-L-Carnitine Prevents Methamphetamine-Induced Structural Damage on Endothelial Cells via ILK-Related MMP-9 Activity. Mol Neurobiol. 2016;53:408-422 pubmed publisher |
| Prakash A, Paunikar S, Webber M, McDermott E, Vellanki S, Thompson K, et al. Centrosome amplification promotes cell invasion via cell-cell contact disruption and Rap-1 activation. J Cell Sci. 2023;136: pubmed publisher |
| Klus xf3 czki x, Ol xe1 h B, Hossz xfa D, Fenyvesi F, Remenyik J, Homoki J, et al. Effectiveness of Anthocyanin-Rich Sour Cherry Extract on Gliadin-Induced Caco-2 Barrier Damage. Nutrients. 2023;15: pubmed publisher |
| Zhang W, Tian Z, Qi X, Chen P, Yang Q, Guan Q, et al. Switching from high-fat diet to normal diet ameliorate BTB integrity and improve fertility potential in obese male mice. Sci Rep. 2023;13:14152 pubmed publisher |
| Krug S, Gr xfc nhagen C, Allers K, Bojarski C, Seybold J, Schneider T, et al. Macromolecule Translocation across the Intestinal Mucosa of HIV-Infected Patients by Transcytosis and through Apoptotic Leaks. Cells. 2023;12: pubmed publisher |
| Wang L, Lei J, Zhao Z, Jia J, Wang L. Therapeutic effects of paeoniflorin on irritable bowel syndrome in rats. J Vet Sci. 2023;24:e23 pubmed publisher |
| Huang C, Yue Q, Sun L, Di K, Yang D, Hao E, et al. Restorative effects of Lactobacillus rhamnosus LR-32 on the gut microbiota, barrier integrity, and 5-HT metabolism in reducing feather-pecking behavior in laying hens with antibiotic-induced dysbiosis. Front Microbiol. 2023;14:1173804 pubmed publisher |
| Li L, Kreye J, Burek M, Cordero Gomez C, Barthel P, S xe1 nchez Send xed n E, et al. Brain blood vessel autoantibodies in patients with NMDA and GABAA receptor encephalitis: identification of unconventional Myosin-X as target antigen. Front Cell Neurosci. 2023;17:1077204 pubmed publisher |
| Awad K, Barmeyer C, Bojarski C, Nagel O, Lee I, Schweiger M, et al. Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M). Cells. 2023;12: pubmed publisher |
| Xu L, Nirwane A, Xu T, Kang M, Devasani K, Yao Y. Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2. Cell Rep. 2022;41:111709 pubmed publisher |
| Delhove J, Alawami M, Macowan M, Lester S, Nguyen P, Jersmann H, et al. Organotypic sinonasal airway culture systems are predictive of the mucociliary phenotype produced by bronchial airway epithelial cells. Sci Rep. 2022;12:19225 pubmed publisher |
| Gong P, Zhang S, Ren L, Zhang J, Zhao Y, Mao X, et al. Electroacupuncture of the trigeminal nerve causes N-methyl-D-aspartate receptors to mediate blood-brain barrier opening and induces neuronal excitatory changes. Front Cell Neurosci. 2022;16:1020644 pubmed publisher |
| Beanland B, McNeill E, Sequeira D, Xue H, Shroyer N, Speer A. Investigation of murine host sex as a biological variable in epithelial barrier function and muscle contractility in human intestinal organoids. FASEB J. 2022;36:e22613 pubmed publisher |
| Ghiselli F, Giovagnoni G, Felici M, Tugnoli B, Piva A, Grilli E. A mixture of organic acids and thymol protects primary chicken intestinal epithelial cells from Clostridium perfringens infection in vitro. Poult Sci. 2022;101:102101 pubmed publisher |
| Yang Y, Yao M, Zeng J, Zheng D, Li Q, Ni Y, et al. FYN regulates cell adhesion at the blood-testis barrier and the apical ectoplasmic specialization via its effect on Arp3 in the mouse testis. Front Immunol. 2022;13:915274 pubmed publisher |
| Tang E, Cheng C. MARK2 and MARK4 Regulate Sertoli Cell BTB Dynamics Through Microtubule and Actin Cytoskeletons. Endocrinology. 2022;163: pubmed publisher |
| Koumangoye R, Penny P, Delpire E. Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression. Am J Physiol Cell Physiol. 2022;323:C1251-C1263 pubmed publisher |
| Jaykumar A, Plumber S, Barry D, Binns D, Wichaidit C, Grzemska M, et al. WNK1 collaborates with TGF-β in endothelial cell junction turnover and angiogenesis. Proc Natl Acad Sci U S A. 2022;119:e2203743119 pubmed publisher |
| Richards M, Nwadozi E, Pal S, Martinsson P, Kaakinen M, Gloger M, et al. Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner. elife. 2022;11: pubmed publisher |
| Schneider K, Mohs A, Gui W, Gálvez E, Candels L, Hoenicke L, et al. Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment. Nat Commun. 2022;13:3964 pubmed publisher |
| Zinserling V, Semenova N, Bikmurzina A, Kruglova N, Rybalchenko O, Markov A. SARS-CoV-2-Induced Pathology-Relevance to COVID-19 Pathophysiology. Pathophysiology. 2022;29:281-297 pubmed publisher |
| Oost M, Ijaz A, van Haarlem D, van Summeren K, Velkers F, Kraneveld A, et al. Chicken-derived RSPO1 and WNT3 contribute to maintaining longevity of chicken intestinal organoid cultures. Sci Rep. 2022;12:10563 pubmed publisher |
| Kim S, Jeong Y, Lee G, Lee J, Lee J, Kim C, et al. Differential expression and localization of tight junction proteins in the goat epididymis. J Anim Sci Technol. 2022;64:500-514 pubmed publisher |
| Meena A, Shukla P, Bell B, Giorgianni F, Caires R, Fernández Peña C, et al. TRPV6 channel mediates alcohol-induced gut barrier dysfunction and systemic response. Cell Rep. 2022;39:110937 pubmed publisher |
| Murata K, Kaji K, Nishimura N, Enomoto M, Fujimoto Y, Takeda S, et al. Rifaximin enhances the L‑carnitine‑mediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gut‑liver‑muscle axis. Int J Mol Med. 2022;50: pubmed publisher |
| Wei xdf F, Czichos C, Knobe L, Voges L, Bojarski C, Michel G, et al. MarvelD3 Is Upregulated in Ulcerative Colitis and Has Attenuating Effects during Colitis Indirectly Stabilizing the Intestinal Barrier. Cells. 2022;11: pubmed publisher |
| Lanza M, Filippone A, Casili G, Giuffr xe8 L, Scuderi S, Paterniti I, et al. Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine. Int J Mol Sci. 2022;23: pubmed publisher |
| Liang X, Xie J, Liu H, Zhao R, Zhang W, Wang H, et al. STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet Cells. Cell Mol Gastroenterol Hepatol. 2022;14:193-217 pubmed publisher |
| Walter F, Harazin A, T xf3 th A, Veszelka S, Santa Maria A, Barna L, et al. Blood-brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells. Fluids Barriers CNS. 2022;19:16 pubmed publisher |
| Hamilton M, Wall E, Robinson C, Guillemin K, Eisen J. Enteric nervous system modulation of luminal pH modifies the microbial environment to promote intestinal health. PLoS Pathog. 2022;18:e1009989 pubmed publisher |
| Song K, Zeng X, Xie X, Zhu R, Liang J, Chen G, et al. Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance. Stroke Vasc Neurol. 2022;7:222-236 pubmed publisher |
| Wu S, Tsai J, Pan H, Arbiser J, Elia L, Sheu M. Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway. Br J Pharmacol. 2022;179:3430-3451 pubmed publisher |
| Qin X, Wang J, Chen S, Liu G, Wu C, Lv Q, et al. Astrocytic p75NTR expression provoked by ischemic stroke exacerbates the blood-brain barrier disruption. Glia. 2022;70:892-912 pubmed publisher |
| Zhang H, Kim H, Park B, Noh M, Kim Y, Park J, et al. CU06-1004 enhances vascular integrity and improves cardiac remodeling by suppressing edema and inflammation in myocardial ischemia-reperfusion injury. Exp Mol Med. 2022;54:23-34 pubmed publisher |
| Hagiwara Y, Kumagai H, Ouwerkerk N, Gijzen L, Annida R, Bokkers M, et al. A Novel In Vitro Membrane Permeability Methodology Using Three-dimensional Caco-2 Tubules in a Microphysiological System Which Better Mimics In Vivo Physiological Conditions. J Pharm Sci. 2022;111:214-224 pubmed publisher |
| Jiang S, Xu Y, Fan Y, Hu Y, Zhang Q, Su W. Busulfan impairs blood-testis barrier and spermatogenesis by increasing noncollagenous 1 domain peptide via matrix metalloproteinase 9. Andrology. 2022;10:377-391 pubmed publisher |
| Chen S, Sun Y, Li F, Zhang X, Hu X, Zhao X, et al. Modulation of α7nAchR by Melatonin Alleviates Ischemia and Reperfusion-Compromised Integrity of Blood-Brain Barrier Through Inhibiting HMGB1-Mediated Microglia Activation and CRTC1-Mediated Neuronal Loss. Cell Mol Neurobiol. 2022;42:2407-2422 pubmed publisher |
| Yu R, Kim N, Li Y, Jeong J, Park S, Zhou B, et al. Vascular Sema3E-Plexin-D1 Signaling Reactivation Promotes Post-stroke Recovery through VEGF Downregulation in Mice. Transl Stroke Res. 2022;13:142-159 pubmed publisher |
| Yanckello L, Hoffman J, Chang Y, Lin P, Nehra G, Chlipala G, et al. Apolipoprotein E genotype-dependent nutrigenetic effects to prebiotic inulin for modulating systemic metabolism and neuroprotection in mice via gut-brain axis. Nutr Neurosci. 2022;25:1669-1679 pubmed publisher |
| Changlin Z, Ying Z, Shuhua Z, Zeng J, Chi H. Research on the Protective Effect of MiR-185-3p Mediated by Huangqin-Tang Decoction (HQT) on the Epithelial Barrier Function of Ulcerative Colitis. Evid Based Complement Alternat Med. 2021;2021:4775606 pubmed publisher |
| Heng S, Samarajeewa N, Wang Y, Paule S, Breen J, Nie G. Podocalyxin promotes an impermeable epithelium and inhibits pro-implantation factors to negatively regulate endometrial receptivity. Sci Rep. 2021;11:24016 pubmed publisher |
| Rancan F, Guo X, Rajes K, Sidiropoulou P, Zabihi F, Hoffmann L, et al. Topical Delivery of Rapamycin by Means of Microenvironment-Sensitive Core-Multi-Shell Nanocarriers: Assessment of Anti-Inflammatory Activity in an ex vivo Skin/T Cell Co-Culture Model. Int J Nanomedicine. 2021;16:7137-7151 pubmed publisher |
| Wang P, Zhang J, Chen Y, Zhong H, Wang H, Li J, et al. Colibactin in avian pathogenic Escherichia coli contributes to the development of meningitis in a mouse model. Virulence. 2021;12:2382-2399 pubmed publisher |
| Abraham H, Ulintz P, Goo L, Yates J, Little A, Bao L, et al. RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers. Front Oncol. 2021;11:712041 pubmed publisher |
| Wu B, Zhou Q, He Z, Wang X, Sun X, Chen Y. Protective Effect of the Abelmoschus manihot Flower Extract on DSS-Induced Ulcerative Colitis in Mice. Evid Based Complement Alternat Med. 2021;2021:7422792 pubmed publisher |
| Lian P, Braber S, Varasteh S, Wichers H, Folkerts G. Hypoxia and heat stress affect epithelial integrity in a Caco-2/HT-29 co-culture. Sci Rep. 2021;11:13186 pubmed publisher |
| Wang R, Song W, Xie C, Zhong W, Xu H, Zhou Q, et al. Urinary Trypsin Inhibitor Protects Tight Junctions of Septic Pulmonary Capillary Endothelial Cells by Regulating the Functions of Macrophages. J Inflamm Res. 2021;14:1973-1989 pubmed publisher |
| Nanou A, Bourbouli M, Vetrano S, Schaeper U, Ley S, Kollias G. Endothelial Tpl2 regulates vascular barrier function via JNK-mediated degradation of claudin-5 promoting neuroinflammation or tumor metastasis. Cell Rep. 2021;35:109168 pubmed publisher |
| Marques M, Costa A, Os xf3 rio H, Pinto M, Relvas S, Dinis Ribeiro M, et al. Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity. Gut Microbes. 2021;13:1-21 pubmed publisher |
| Uprety T, Sreenivasan C, Bhattarai S, Wang D, Kaushik R, Li F. Isolation and development of bovine primary respiratory cells as model to study influenza D virus infection. Virology. 2021;559:89-99 pubmed publisher |
| Xia F, Ha Y, Shi S, Li Y, Li S, Luisi J, et al. Early alterations of neurovascular unit in the retina in mouse models of tauopathy. Acta Neuropathol Commun. 2021;9:51 pubmed publisher |
| Tratnjek L, Sibinovska N, Kralj S, Makovec D, Kristan K, Kreft M. Standardization of esophageal adenocarcinoma in vitro model and its applicability for model drug testing. Sci Rep. 2021;11:6664 pubmed publisher |
| Hargest V, Davis A, Tan S, Cortez V, Schultz Cherry S. Human Astroviruses: A Tale of Two Strains. Viruses. 2021;13: pubmed publisher |
| Buzhdygan T, Rodrigues C, McGary H, Khan J, Andrews A, Rawls S, et al. The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties. J Neuroinflammation. 2021;18:63 pubmed publisher |
| Ezquer F, Quintanilla M, Moya Flores F, Morales P, Munita J, Olivares B, et al. Innate gut microbiota predisposes to high alcohol consumption. Addict Biol. 2021;26:e13018 pubmed publisher |
| Bai H, Zhou R, Barravecchia M, Norman R, Friedman A, Yu D, et al. The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα. JCI Insight. 2021;6: pubmed publisher |
| Tinh N, Sitolo G, Yamamoto Y, Suzuki T. Citrus limon Peel Powder Reduces Intestinal Barrier Defects and Inflammation in a Colitic Murine Experimental Model. Foods. 2021;10: pubmed publisher |
| Xu J, Kausalya P, Van Hul N, Caldez M, Xu S, Ong A, et al. Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis. Gastroenterology. 2021;160:2103-2118 pubmed publisher |
| Schneider K, Elfers C, Ghallab A, Schneider C, Gálvez E, Mohs A, et al. Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury. Cell Mol Gastroenterol Hepatol. 2021;11:909-933 pubmed publisher |
| Nian S, Kearns V, Wong D, Bachhuka A, Vasilev K, Williams R, et al. Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space. J Tissue Eng Regen Med. 2021;15:49-62 pubmed publisher |
| An G, Lu F, Huang S, Bai J, He L, Liu Y, et al. Effects of miR‑93 on epithelial‑to‑mesenchymal transition and vasculogenic mimicry in triple‑negative breast cancer cells. Mol Med Rep. 2021;23: pubmed publisher |
| Tawfik A, Mohamed R, Kira D, Alhusban S, Al Shabrawey M. N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood-retinal barrier dysfunction. J Mol Med (Berl). 2021;99:119-130 pubmed publisher |
| Villota S, Toledo Rodriguez M, Leach L. Compromised barrier integrity of human feto-placental vessels from gestational diabetic pregnancies is related to downregulation of occludin expression. Diabetologia. 2021;64:195-210 pubmed publisher |
| Kempf N, Moutahir F, Goiffon I, Cantaloube S, Bystricky K, Lavigne A. Analysis of Cellular EMT States Using Molecular Biology and High Resolution FISH Labeling. Methods Mol Biol. 2021;2179:353-383 pubmed publisher |
| El Chami C, Foster A, Johnson C, Clausen R, Cornwell P, Haslam I, et al. Organic osmolytes increase expression of specific tight junction proteins in skin and alter barrier function in keratinocytes. Br J Dermatol. 2021;184:482-494 pubmed publisher |
| Ramuta T, Jerman U, Tratnjek L, Janev A, Magatti M, Vertua E, et al. The Cells and Extracellular Matrix of Human Amniotic Membrane Hinder the Growth and Invasive Potential of Bladder Urothelial Cancer Cells. Front Bioeng Biotechnol. 2020;8:554530 pubmed publisher |
| Scuderi S, Casili G, Lanza M, Filippone A, Paterniti I, Esposito E, et al. Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome. Biomedicines. 2020;8: pubmed publisher |
| Zhang S, Gong P, Zhang J, Mao X, Zhao Y, Wang H, et al. Specific Frequency Electroacupuncture Stimulation Transiently Enhances the Permeability of the Blood-Brain Barrier and Induces Tight Junction Changes. Front Neurosci. 2020;14:582324 pubmed publisher |
| Aguanno D, Coquant G, Postal B, Osinski C, Wieckowski M, Stockholm D, et al. The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption. Tissue Barriers. 2020;8:1832877 pubmed publisher |
| Le Roy L, Amara A, Le Roux C, Bocher O, L xe9 tondor A, Benz N, et al. Principal component analysis, a useful tool to study cyclin-dependent kinase-inhibitor's effect on cerebral ischaemia. Brain Commun. 2020;2:fcaa136 pubmed publisher |
| Yamashita K, Mizuno K, Furukawa K, Hirose H, Sakurai N, Masuda Hirata M, et al. Phosphorylation and dephosphorylation of Ser852 and Ser889 control the clustering, localization and function of PAR3. J Cell Sci. 2020;133: pubmed publisher |
| Torices S, Roberts S, Park M, Malhotra A, Toborek M. Occludin, caveolin-1, and Alix form a multi-protein complex and regulate HIV-1 infection of brain pericytes. FASEB J. 2020;34:16319-16332 pubmed publisher |
| Cui J, Shipley F, Shannon M, Alturkistani O, Dani N, Webb M, et al. Inflammation of the Embryonic Choroid Plexus Barrier following Maternal Immune Activation. Dev Cell. 2020;55:617-628.e6 pubmed publisher |
| Wrenn E, Yamamoto A, Moore B, Huang Y, McBirney M, Thomas A, et al. Regulation of Collective Metastasis by Nanolumenal Signaling. Cell. 2020;183:395-410.e19 pubmed publisher |
| Zhou X, Brown B, Siegel A, El Masry M, Zeng X, Song W, et al. Exosome-Mediated Crosstalk between Keratinocytes and Macrophages in Cutaneous Wound Healing. ACS Nano. 2020;14:12732-12748 pubmed publisher |
| Cobo Calvo A, Ruiz A, Richard C, Blondel S, Cavagna S, Strazielle N, et al. Purified IgG from aquaporin-4 neuromyelitis optica spectrum disorder patients alters blood-brain barrier permeability. PLoS ONE. 2020;15:e0238301 pubmed publisher |
| Duarte Lobo D, Nobre R, Oliveira Miranda C, Pereira D, Castelhano J, Sereno J, et al. The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples. Acta Neuropathol Commun. 2020;8:152 pubmed publisher |
| Trushko A, Di Meglio I, Merzouki A, Blanch Mercader C, Abuhattum S, Guck J, et al. Buckling of an Epithelium Growing under Spherical Confinement. Dev Cell. 2020;54:655-668.e6 pubmed publisher |
| Wang H, Jiang Y, Li H, Wang J, Li C, Zhang D. Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton. Exp Ther Med. 2020;20:2828-2837 pubmed publisher |
| Filippone A, Consoli G, Granata G, Casili G, Lanza M, Ardizzone A, et al. Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model. Int J Mol Sci. 2020;21: pubmed publisher |
| Wei Z, Shen P, Cheng P, Lu Y, Wang A, Sun Z. Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits. Oxid Med Cell Longev. 2020;2020:2375676 pubmed publisher |
| Wang W, Tam K, Ng T, Goit R, Chan K, Lo A. Long-term lutein administration attenuates retinal inflammation and functional deficits in early diabetic retinopathy using the Ins2Akita/+ mice. BMJ Open Diabetes Res Care. 2020;8: pubmed publisher |
| Hung W, Wang C, Lin S, Cheng S, Liao L, Lu L, et al. Leptin protects brain from ischemia/reperfusion-induced infarction by stabilizing the blood-brain barrier to block brain infiltration by the blood-borne neutrophils. Eur J Neurosci. 2020;52:4890-4907 pubmed publisher |
| Onozato D, Akagawa T, Kida Y, Ogawa I, Hashita T, Iwao T, et al. Application of Human Induced Pluripotent Stem Cell-Derived Intestinal Organoids as a Model of Epithelial Damage and Fibrosis in Inflammatory Bowel Disease. Biol Pharm Bull. 2020;43:1088-1095 pubmed publisher |
| Wang Z, Zhen Z, Fan D, Qin C, Han D, Zhou H, et al. Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic Macrophages. J Virol. 2020;94: pubmed publisher |
| Erikson K, Tuominen H, Vakkala M, Liisanantti J, Karttunen T, Syrjala H, et al. Brain tight junction protein expression in sepsis in an autopsy series. Crit Care. 2020;24:385 pubmed publisher |
| Gijzen L, Marescotti D, Raineri E, Nicolas A, Lanz H, Guerrera D, et al. An Intestine-on-a-Chip Model of Plug-and-Play Modularity to Study Inflammatory Processes. SLAS Technol. 2020;25:585-597 pubmed publisher |
| Lio D, Chia R, Kwek M, Wiraja C, Madden L, Chang H, et al. Temporal pressure enhanced topical drug delivery through micropore formation. Sci Adv. 2020;6:eaaz6919 pubmed publisher |
| Marcu I, Eberhard N, Yerly A, Balmer V, Hemphill A, Mogel H, et al. Isolation of Human Small Extracellular Vesicles and Tracking of their Uptake by Retinal Pigment Epithelial Cells In Vitro. Int J Mol Sci. 2020;21: pubmed publisher |
| Pardyak L, Kaminska A, Brzoskwinia M, Hejmej A, Kotula Balak M, Jankowski J, et al. Differential expression of cell-cell junction proteins in the testis, epididymis, and ductus deferens of domestic turkeys (Meleagris gallopavo) with white and yellow semen. Poult Sci. 2020;99:555-566 pubmed publisher |
| Postal B, Ghezzal S, Aguanno D, Andre S, Garbin K, Genser L, et al. AhR activation defends gut barrier integrity against damage occurring in obesity. Mol Metab. 2020;39:101007 pubmed publisher |
| Rom S, Heldt N, Gajghate S, Seliga A, Reichenbach N, Persidsky Y. Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles. Sci Rep. 2020;10:7274 pubmed publisher |
| Wu C, Lu M, Feng X, Nakato G, Udey M. Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins. Cells. 2020;9: pubmed publisher |
| He S, Guo Y, Zhao J, Xu X, Wang N, Liu Q. Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells. Front Pharmacol. 2020;11:376 pubmed publisher |
| Badu Nkansah K, Lechler T. Proteomic analysis of desmosomes reveals novel components required for epidermal integrity. Mol Biol Cell. 2020;31:1140-1153 pubmed publisher |
| Kim B, Im N, Yang T, Kim J, Jung K, Kim T, et al. Enhancement of aberrantly modified integrin‑mediated cell motility in multicellular tumor spheroids. Int J Oncol. 2020;56:1490-1498 pubmed publisher |
| Aoki H, Yamashita M, Hashita T, Iwao T, Matsunaga T. Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity. Fluids Barriers CNS. 2020;17:25 pubmed publisher |
| Kjærgaard S, Damm M, Chang J, Riis L, Rasmussen H, Hytting Andreasen R, et al. Altered Structural Expression and Enzymatic Activity Parameters in Quiescent Ulcerative Colitis: Are These Potential Normalization Criteria?. Int J Mol Sci. 2020;21: pubmed publisher |
| Molloy K, Cagney G, Dillon E, Wynne K, Greene C, McElvaney N. Impaired Airway Epithelial Barrier Integrity in Response to Stenotrophomonas maltophilia Proteases, Novel Insights Using Cystic Fibrosis Bronchial Epithelial Cell Secretomics. Front Immunol. 2020;11:198 pubmed publisher |
| Roudnicky F, Kim B, Lan Y, Schmucki R, Küppers V, Christensen K, et al. Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance. Sci Rep. 2020;10:3886 pubmed publisher |
| Krüger L, Pridgen T, Taylor E, Garman K, Blikslager A. Lubiprostone protects esophageal mucosa from acid injury in porcine esophagus. Am J Physiol Gastrointest Liver Physiol. 2020;318:G613-G623 pubmed publisher |
| Su L, Wang Z, Xie S, Hu D, Cheng Y, Mruk D, et al. Testin regulates the blood-testis barrier via disturbing occludin/ZO-1 association and actin organization. J Cell Physiol. 2020;235:6127-6138 pubmed publisher |
| Kobayashi K, Tsugami Y, Suzuki N, Suzuki T, Nishimura T. Nicotine directly affects milk production in lactating mammary epithelial cells concurrently with inactivation of STAT5 and glucocorticoid receptor in vitro. Toxicol In Vitro. 2020;63:104741 pubmed publisher |
| Rivera J, Isidro R, Loucil Alicea R, Cruz M, Appleyard C, Isidro A, et al. Infusion of HIV-1 Nef-expressing astrocytes into the rat hippocampus induces enteropathy and interstitial pneumonitis and increases blood-brain-barrier permeability. PLoS ONE. 2019;14:e0225760 pubmed publisher |
| Alvarez R, Stork C, Sayoc Becerra A, MARCHELLETTA R, Prisk G, McCole D. A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function. Sci Rep. 2019;9:17531 pubmed publisher |
| Sayoc Becerra A, Krishnan M, Fan S, Jimenez J, HERNANDEZ R, Gibson K, et al. The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction. Inflamm Bowel Dis. 2020;26:407-422 pubmed publisher |
| Valque H, Gouyer V, Duez C, Leboeuf C, Marquillies P, Le Bert M, et al. Muc5b-deficient mice develop early histological lung abnormalities. Biol Open. 2019;8: pubmed publisher |
| Su W, Cheng C. Cdc42 is involved in NC1 peptide-regulated BTB dynamics through actin and microtubule cytoskeletal reorganization. FASEB J. 2019;33:14461-14478 pubmed publisher |
| Bernatz S, Ilina E, Devraj K, Harter P, Mueller K, Kleber S, et al. Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases. J Exp Clin Cancer Res. 2019;38:434 pubmed publisher |
| Ghezzal S, Postal B, Quévrain E, Brot L, Seksik P, Leturque A, et al. Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158530 pubmed publisher |
| Mehdizadeh Gohari I, Li J, Navarro M, Uzal F, McClane B. Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells. Toxins (Basel). 2019;11: pubmed publisher |
| Ye J, Luo D, Xu X, Sun M, Su X, Tian Z, et al. Metformin Improves Fertility in Obese Males by Alleviating Oxidative Stress-Induced Blood-Testis Barrier Damage. Oxid Med Cell Longev. 2019;2019:9151067 pubmed publisher |
| An G, Wu F, Huang S, Feng L, Bai J, Gu S, et al. Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages. Oncol Rep. 2019;42:2499-2511 pubmed publisher |
| Miranda J, Martín Tapia D, Valdespino Vazquez Y, Alarcón L, Espejel Nuñez A, Guzmán Huerta M, et al. Syncytiotrophoblast of Placentae from Women with Zika Virus Infection Has Altered Tight Junction Protein Expression and Increased Paracellular Permeability. Cells. 2019;8: pubmed publisher |
| Castro Dias M, Coisne C, Baden P, Enzmann G, Garrett L, Becker L, et al. Claudin-12 is not required for blood-brain barrier tight junction function. Fluids Barriers CNS. 2019;16:30 pubmed publisher |
| Giménez Gómez P, Pérez Hernández M, O Shea E, Caso J, Martín Hernández D, Cervera L, et al. Changes in brain kynurenine levels via gut microbiota and gut-barrier disruption induced by chronic ethanol exposure in mice. FASEB J. 2019;33:12900-12914 pubmed publisher |
| Halder S, Matsunaga H, Ueda H. Prothymosin alpha and its mimetic hexapeptide improve delayed tissue plasminogen activator-induced brain damage following cerebral ischemia. J Neurochem. 2020;153:772-789 pubmed publisher |
| Luo S, Terciolo C, Bracarense A, Payros D, Pinton P, Oswald I. In vitro and in vivo effects of a mycotoxin, deoxynivalenol, and a trace metal, cadmium, alone or in a mixture on the intestinal barrier. Environ Int. 2019;132:105082 pubmed publisher |
| Smith N, Germundson D, Combs C, Vendsel L, Nagamoto Combs K. Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy. Front Cell Neurosci. 2019;13:320 pubmed publisher |
| Yang R, Hui Q, Jiang Q, Liu S, Zhang H, Wu J, et al. Effect of Manitoba-Grown Red-Osier Dogwood Extracts on Recovering Caco-2 Cells from H2O2-Induced Oxidative Damage. Antioxidants (Basel). 2019;8: pubmed publisher |
| Cremonini E, Daveri E, Mastaloudis A, Adamo A, Mills D, Kalanetra K, et al. Anthocyanins protect the gastrointestinal tract from high fat diet-induced alterations in redox signaling, barrier integrity and dysbiosis. Redox Biol. 2019;26:101269 pubmed publisher |
| Leo L, Familusi B, Hoang M, Smith R, Lindenau K, Sporici K, et al. GPR55-mediated effects on brain microvascular endothelial cells and the blood-brain barrier. Neuroscience. 2019;414:88-98 pubmed publisher |
| Rankin C, Lokhandwala Z, Huang R, Pekow J, Pothoulakis C, Padua D. Linear and circular CDKN2B-AS1 expression is associated with Inflammatory Bowel Disease and participates in intestinal barrier formation. Life Sci. 2019;:116571 pubmed publisher |
| Salas Perdomo A, Miro Mur F, Gallizioli M, Brait V, Justicia C, Meissner A, et al. Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke. Sci Rep. 2019;9:8309 pubmed publisher |
| Boschetti E, Accarino A, Malagelada C, Malagelada J, Cogliandro R, Gori A, et al. Gut epithelial and vascular barrier abnormalities in patients with chronic intestinal pseudo-obstruction. Neurogastroenterol Motil. 2019;31:e13652 pubmed publisher |
| Yan M, Li L, Mao B, Li H, Li S, Mruk D, et al. mTORC1/rpS6 signaling complex modifies BTB transport function: an in vivo study using the adjudin model. Am J Physiol Endocrinol Metab. 2019;317:E121-E138 pubmed publisher |
| Zhao Q, Zhang F, Yu Z, Guo S, Liu N, Jiang Y, et al. HDAC3 inhibition prevents blood-brain barrier permeability through Nrf2 activation in type 2 diabetes male mice. J Neuroinflammation. 2019;16:103 pubmed publisher |
| Leguina Ruzzi A, Ortiz Diban R, Velarde V. The 12-HHT/BLT2/NO Axis Is Associated to the Wound Healing and Skin Condition in Different Glycaemic States. Med Sci (Basel). 2019;7: pubmed publisher |
| Hsieh J, Rathore A, Soundarajan G, St John A. Japanese encephalitis virus neuropenetrance is driven by mast cell chymase. Nat Commun. 2019;10:706 pubmed publisher |
| Tan C, Lu N, Wang C, Chen D, Sun N, Lyu H, et al. Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4. Neuron. 2019;101:920-937.e13 pubmed publisher |
| Hu Y, Do J, Edamakanti C, Kini A, Martina M, Stupp S, et al. Self-assembling vascular endothelial growth factor nanoparticles improve function in spinocerebellar ataxia type 1. Brain. 2019;142:312-321 pubmed publisher |
| Villella V, Venerando A, Cozza G, Esposito S, Ferrari E, Monzani R, et al. A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease. EMBO J. 2019;38: pubmed publisher |
| Marques M, Melo J, Cavadas B, Mendes N, Pereira L, Carneiro F, et al. Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells. Front Microbiol. 2018;9:2712 pubmed publisher |
| Zhao Q, Yu Z, Zhang F, Huang L, Xing C, Liu N, et al. HDAC3 inhibition prevents oxygen glucose deprivation/reoxygenation-induced transendothelial permeability by elevating PPARγ activity in vitro. J Neurochem. 2019;149:298-310 pubmed publisher |
| Fang M, Zhong W, Song W, Deng Y, Yang D, Xiong B, et al. Ulinastatin Ameliorates Pulmonary Capillary Endothelial Permeability Induced by Sepsis Through Protection of Tight Junctions via Inhibition of TNF-α and Related Pathways. Front Pharmacol. 2018;9:823 pubmed publisher |
| Wen Q, Tang E, Lui W, Lee W, Wong C, Silvestrini B, et al. Dynein 1 supports spermatid transport and spermiation during spermatogenesis in the rat testis. Am J Physiol Endocrinol Metab. 2018;315:E924-E948 pubmed publisher |
| He S, Guo Y, Zhao J, Xu X, Song J, Wang N, et al. Ferulic acid protects against heat stress-induced intestinal epithelial barrier dysfunction in IEC-6 cells via the PI3K/Akt-mediated Nrf2/HO-1 signaling pathway. Int J Hyperthermia. 2019;35:112-121 pubmed publisher |
| Genser L, Aguanno D, Soula H, Dong L, Trystram L, Assmann K, et al. Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes. J Pathol. 2018;246:217-230 pubmed publisher |
| Shimojo Y, Ozawa Y, Toda T, Igami K, Shimizu T. Probiotic Lactobacillus paracasei A221 improves the functionality and bioavailability of kaempferol-glucoside in kale by its glucosidase activity. Sci Rep. 2018;8:9239 pubmed publisher |
| Abdul Y, Abdelsaid M, Li W, Webb R, Sullivan J, Dong G, et al. Inhibition of Toll-Like Receptor-4 (TLR-4) Improves Neurobehavioral Outcomes After Acute Ischemic Stroke in Diabetic Rats: Possible Role of Vascular Endothelial TLR-4. Mol Neurobiol. 2019;56:1607-1617 pubmed publisher |
| Ved N, Da Vitoria Lobo M, Bestall S, L Vidueira C, Beazley Long N, Ballmer Hofer K, et al. Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain. J Physiol. 2018;596:3675-3693 pubmed publisher |
| Shigetomi K, Ono Y, Inai T, Ikenouchi J. Adherens junctions influence tight junction formation via changes in membrane lipid composition. J Cell Biol. 2018;217:2373-2381 pubmed publisher |
| Onozato D, Yamashita M, Nakanishi A, Akagawa T, Kida Y, Ogawa I, et al. Generation of Intestinal Organoids Suitable for Pharmacokinetic Studies from Human Induced Pluripotent Stem Cells. Drug Metab Dispos. 2018;46:1572-1580 pubmed publisher |
| Clayton A, Shao Q, Paauw N, Giambrone A, Granger J, Warrington J. Postpartum increases in cerebral edema and inflammation in response to placental ischemia during pregnancy. Brain Behav Immun. 2018;70:376-389 pubmed publisher |
| Wasén C, Ekstrand M, Levin M, Giglio D. Epidermal growth factor receptor function in the human urothelium. Int Urol Nephrol. 2018;50:647-656 pubmed publisher |
| Singh A, Sharma S, Pagarware K, Siraji R, Ansari I, Mandal A, et al. Enteropathogenic E. coli effectors EspF and Map independently disrupt tight junctions through distinct mechanisms involving transcriptional and post-transcriptional regulation. Sci Rep. 2018;8:3719 pubmed publisher |
| Kanda Y, Yamasaki Y, Sasaki Yamaguchi Y, Ida Koga N, Kamisuki S, Sugawara F, et al. TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin. Sci Rep. 2018;8:2251 pubmed publisher |
| Yu J, Li C, Ding Q, Que J, Liu K, Wang H, et al. Netrin-1 Ameliorates Blood-Brain Barrier Impairment Secondary to Ischemic Stroke via the Activation of PI3K Pathway. Front Neurosci. 2017;11:700 pubmed publisher |
| Rijnsburger M, Unmehopa U, Eggels L, Serlie M, La Fleur S. One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats. Nutr Neurosci. 2019;22:541-550 pubmed publisher |
| Jaworska K, Huc T, Samborowska E, Dobrowolski L, Bielinska K, Gawlak M, et al. Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite. PLoS ONE. 2017;12:e0189310 pubmed publisher |
| Zhou S, Gillilland M, Wu X, Leelasinjaroen P, Zhang G, Zhou H, et al. FODMAP diet modulates visceral nociception by lipopolysaccharide-mediated intestinal inflammation and barrier dysfunction. J Clin Invest. 2018;128:267-280 pubmed publisher |
| Wu D, Huang C, Jiao X, Ding Z, Zhang J, Chen F, et al. Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells. Oncotarget. 2017;8:88630-88644 pubmed publisher |
| Sciacca G, Cicchetti F. Mutant huntingtin protein expression and blood-spinal cord barrier dysfunction in huntington disease. Ann Neurol. 2017;82:981-994 pubmed publisher |
| Cremonini E, Wang Z, Bettaieb A, Adamo A, Daveri E, Mills D, et al. (-)-Epicatechin protects the intestinal barrier from high fat diet-induced permeabilization: Implications for steatosis and insulin resistance. Redox Biol. 2018;14:588-599 pubmed publisher |
| Shimada H, Satohisa S, Kohno T, Konno T, Takano K, Takahashi S, et al. Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer. Oncol Lett. 2017;14:6776-6782 pubmed publisher |
| Higuita Castro N, Nelson M, Shukla V, Agudelo Garcia P, Zhang W, Duarte Sanmiguel S, et al. Using a Novel Microfabricated Model of the Alveolar-Capillary Barrier to Investigate the Effect of Matrix Structure on Atelectrauma. Sci Rep. 2017;7:11623 pubmed publisher |
| Brandt A, Jin C, Nolte K, Sellmann C, Engstler A, Bergheim I. Short-Term Intake of a Fructose-, Fat- and Cholesterol-Rich Diet Causes Hepatic Steatosis in Mice: Effect of Antibiotic Treatment. Nutrients. 2017;9: pubmed publisher |
| Dumont A, Cianciotto N. Stenotrophomonas maltophilia Serine Protease StmPr1 Induces Matrilysis, Anoikis, and Protease-Activated Receptor 2 Activation in Human Lung Epithelial Cells. Infect Immun. 2017;85: pubmed publisher |
| Trietsch S, Naumovska E, Kurek D, Setyawati M, Vormann M, Wilschut K, et al. Membrane-free culture and real-time barrier integrity assessment of perfused intestinal epithelium tubes. Nat Commun. 2017;8:262 pubmed publisher |
| Izawa Y, Gu Y, Osada T, Kanazawa M, Hawkins B, Koziol J, et al. β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability. J Cereb Blood Flow Metab. 2018;38:641-658 pubmed publisher |
| Wang C, Ahmed M, Jiang Q, Lu N, Tan C, Gao Y, et al. Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator. J Pineal Res. 2017;63: pubmed publisher |
| Sauer R, Kirchner J, Yang S, Hu L, Leinders M, Sommer C, et al. Blood-spinal cord barrier breakdown and pericyte deficiency in peripheral neuropathy. Ann N Y Acad Sci. 2017;1405:71-88 pubmed publisher |
| Kearns V, Tasker J, Zhuola -, Akhtar R, Bachhuka A, Vasilev K, et al. The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry. J Mater Sci Mater Med. 2017;28:124 pubmed publisher |
| Zhang J, Wang Y, Chen J, Zhang X, Dong J, Tsang L, et al. Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis. Sci Rep. 2017;7:5233 pubmed publisher |
| Ly H, Verma N, Wu F, Liu M, Saatman K, Nelson P, et al. Brain microvascular injury and white matter disease provoked by diabetes-associated hyperamylinemia. Ann Neurol. 2017;82:208-222 pubmed publisher |
| Sheng Z, Gao N, Wang Z, Cui X, Zhou D, Fan D, et al. Sertoli Cells Are Susceptible to ZIKV Infection in Mouse Testis. Front Cell Infect Microbiol. 2017;7:272 pubmed publisher |
| Kern M, Günzel D, Aschenbach J, Tedin K, Bondzio A, Lodemann U. Altered Cytokine Expression and Barrier Properties after In Vitro Infection of Porcine Epithelial Cells with Enterotoxigenic Escherichia coli and Probiotic Enterococcus faecium. Mediators Inflamm. 2017;2017:2748192 pubmed publisher |
| Neuhaus W, Kramer T, Neuhoff A, Gölz C, Thal S, Förster C. Multifaceted Mechanisms of WY-14643 to Stabilize the Blood-Brain Barrier in a Model of Traumatic Brain Injury. Front Mol Neurosci. 2017;10:149 pubmed publisher |
| Chen H, Mruk D, Lee W, Cheng C. Regulation of spermatogenesis by a local functional axis in the testis: role of the basement membrane-derived noncollagenous 1 domain peptide. FASEB J. 2017;31:3587-3607 pubmed publisher |
| Fan H, Qiao L, Kang K, Fan J, Wei W, Luo G. Attachment and Postattachment Receptors Important for Hepatitis C Virus Infection and Cell-to-Cell Transmission. J Virol. 2017;91: pubmed publisher |
| Di Pietro M, Pascuali N, Scotti L, Irusta G, Bas D, May M, et al. In vivo intrabursal administration of bioactive lipid sphingosine-1-phosphate enhances vascular integrity in a rat model of ovarian hyperstimulation syndrome. Mol Hum Reprod. 2017;23:417-427 pubmed publisher |
| Luo H, Zhou D, Chen Z, Zhou Q, Wu K, Tian K, et al. Establishment and evaluation of an experimental rat model for high-altitude intestinal barrier injury. Exp Ther Med. 2017;13:475-482 pubmed publisher |
| Huggins M, Johnson H, Jin F, N Songo A, Hanson L, Lafrance S, et al. Perforin Expression by CD8 T Cells Is Sufficient To Cause Fatal Brain Edema during Experimental Cerebral Malaria. Infect Immun. 2017;85: pubmed publisher |
| Obert E, Strauss R, Brandon C, Grek C, Ghatnekar G, GOURDIE R, et al. Targeting the tight junction protein, zonula occludens-1, with the connexin43 mimetic peptide, αCT1, reduces VEGF-dependent RPE pathophysiology. J Mol Med (Berl). 2017;95:535-552 pubmed publisher |
| Rolland Fourcade C, Denadai Souza A, Cirillo C, Lopez C, Jaramillo J, Desormeaux C, et al. Epithelial expression and function of trypsin-3 in irritable bowel syndrome. Gut. 2017;66:1767-1778 pubmed publisher |
| Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed publisher |
| Mohaddes G, Abdolalizadeh J, Babri S, Hossienzadeh F. Ghrelin ameliorates blood-brain barrier disruption during systemic hypoxia. Exp Physiol. 2017;102:376-382 pubmed publisher |
| Theriault P, ElAli A, Rivest S. High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice. Oncotarget. 2016;7:67808-67827 pubmed publisher |
| Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, et al. Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016;7:11876 pubmed publisher |
| Sántha P, Veszelka S, Hoyk Z, Mészáros M, Walter F, Tóth A, et al. Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats. Front Mol Neurosci. 2015;8:88 pubmed publisher |
| Merino V, Nguyen N, Jin K, Sadik H, Cho S, Korangath P, et al. Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer. Cancer Res. 2016;76:2013-2024 pubmed publisher |
| Rodrigo Albors A, Tazaki A, Rost F, Nowoshilow S, Chara O, Tanaka E. Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration. elife. 2015;4:e10230 pubmed publisher |
| Sang H, Liu L, Wang L, Qiu Z, Li M, Yu L, et al. Opposite roles of bradykinin B1 and B2 receptors during cerebral ischaemia-reperfusion injury in experimental diabetic rats. Eur J Neurosci. 2016;43:53-65 pubmed publisher |
| Vandenhaute E, Stump Guthier C, Losada M, Tenenbaum T, Rudolph H, Ishikawa H, et al. The choroid plexus may be an underestimated site of tumor invasion to the brain: an in vitro study using neuroblastoma cell lines. Cancer Cell Int. 2015;15:102 pubmed publisher |
| Freedman B, Brooks C, Lam A, Fu H, Morizane R, Agrawal V, et al. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nat Commun. 2015;6:8715 pubmed publisher |
| Kim C, Kim J, Jo K, Lee Y, Sohn E, Yoo N, et al. OSSC1E-K19, a novel phytochemical component of Osteomeles schwerinae, prevents glycated albumin-induced retinal vascular injury in rats. Mol Med Rep. 2015;12:7279-84 pubmed publisher |
| MartÃnez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed publisher |
| Tan F, Fu W, Cheng N, Meng D, Gu Y. Ligustrazine reduces blood-brain barrier permeability in a rat model of focal cerebral ischemia and reperfusion. Exp Ther Med. 2015;9:1757-1762 pubmed |
| Goichon A, Bertrand J, Chan P, Lecleire S, Coquard A, Cailleux A, et al. Enteral delivery of proteins enhances the expression of proteins involved in the cytoskeleton and protein biosynthesis in human duodenal mucosa. Am J Clin Nutr. 2015;102:359-67 pubmed publisher |
| Chang C, Lin C, Lu C, Martel J, Ko Y, Ojcius D, et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nat Commun. 2015;6:7489 pubmed publisher |
| Ek C, D Angelo B, Lehner C, Nathanielsz P, Li C, Mallard C. Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas). Reprod Toxicol. 2015;56:32-44 pubmed publisher |
| Li N, Mruk D, Wong C, Lee W, Han D, Cheng C. Actin-bundling protein plastin 3 is a regulator of ectoplasmic specialization dynamics during spermatogenesis in the rat testis. FASEB J. 2015;29:3788-805 pubmed publisher |
| Suárez Causado A, Caballero DÃaz D, Bertrán E, Roncero C, Addante A, GarcÃa Ãlvaro M, et al. HGF/c-Met signaling promotes liver progenitor cell migration and invasion by an epithelial-mesenchymal transition-independent, phosphatidyl inositol-3 kinase-dependent pathway in an in vitro model. Biochim Biophys Acta. 2015;1853:2453-63 pubmed publisher |
| Son Y, Heo K, Bae M, Lee C, Cho W, Kim S, et al. Injury to the blood-testis barrier after low-dose-rate chronic radiation exposure in mice. Radiat Prot Dosimetry. 2015;167:316-20 pubmed publisher |
| Staat C, Coisne C, Dabrowski S, Stamatovic S, Andjelkovic A, Wolburg H, et al. Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers. Biomaterials. 2015;54:9-20 pubmed publisher |
| Pothoven K, Norton J, Hulse K, Suh L, Carter R, Rocci E, et al. Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease. J Allergy Clin Immunol. 2015;136:737-746.e4 pubmed publisher |
| Muramatsu R, Kuroda M, Matoba K, Lin H, Takahashi C, Koyama Y, et al. Prostacyclin prevents pericyte loss and demyelination induced by lysophosphatidylcholine in the central nervous system. J Biol Chem. 2015;290:11515-25 pubmed publisher |
| Furihata T, Kawamatsu S, Ito R, Saito K, Suzuki S, Kishida S, et al. Hydrocortisone enhances the barrier properties of HBMEC/ciβ, a brain microvascular endothelial cell line, through mesenchymal-to-endothelial transition-like effects. Fluids Barriers CNS. 2015;12:7 pubmed publisher |
| Boulay A, Mazeraud A, Cisternino S, Saubaméa B, Mailly P, Jourdren L, et al. Immune quiescence of the brain is set by astroglial connexin 43. J Neurosci. 2015;35:4427-39 pubmed publisher |
| ErLin S, WenJie W, LiNing W, BingXin L, MingDe L, Yan S, et al. Musashi-1 maintains blood-testis barrier structure during spermatogenesis and regulates stress granule formation upon heat stress. Mol Biol Cell. 2015;26:1947-56 pubmed publisher |
| Ek C, D Angelo B, Baburamani A, Lehner C, Leverin A, Smith P, et al. Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia. J Cereb Blood Flow Metab. 2015;35:818-27 pubmed publisher |
| Peng H, Li C, Kadow S, Henry B, Steinmann J, Becker K, et al. Acid sphingomyelinase inhibition protects mice from lung edema and lethal Staphylococcus aureus sepsis. J Mol Med (Berl). 2015;93:675-89 pubmed publisher |
| Chen M, Yang T, Meng X, Sun T. Azithromycin attenuates cigarette smoke extract-induced oxidative stress injury in human alveolar epithelial cells. Mol Med Rep. 2015;11:3414-22 pubmed publisher |
| Li Z, Liu Y, Liu X, Xue Y, Wang P, Liu L. Low-dose endothelial monocyte-activating polypeptide-II increases permeability of blood-tumor barrier via a PKC-ζ/PP2A-dependent signaling mechanism. Exp Cell Res. 2015;331:257-66 pubmed publisher |
| Kreft M, Jerman U, LasiÄ E, Hevir Kene N, Rižner T, Peternel L, et al. The characterization of the human cell line Calu-3 under different culture conditions and its use as an optimized in vitro model to investigate bronchial epithelial function. Eur J Pharm Sci. 2015;69:1-9 pubmed publisher |
| Tang E, Mok K, Lee W, Cheng C. EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. Endocrinology. 2015;156:680-93 pubmed publisher |
| Kreft M, Jerman U, LasiÄ E, LaniÅ¡nik Rižner T, Hevir Kene N, Peternel L, et al. The characterization of the human nasal epithelial cell line RPMI 2650 under different culture conditions and their optimization for an appropriate in vitro nasal model. Pharm Res. 2015;32:665-79 pubmed publisher |
| Crespi A, Bertoni A, Ferrari I, Padovano V, Della Mina P, Berti E, et al. POF1B localizes to desmosomes and regulates cell adhesion in human intestinal and keratinocyte cell lines. J Invest Dermatol. 2015;135:192-201 pubmed publisher |
| Retana C, Sanchez E, Perez Lopez A, Cruz A, Lagunas J, Cruz C, et al. Alterations of intercellular junctions in peritoneal mesothelial cells from patients undergoing dialysis: effect of retinoic Acid. Perit Dial Int. 2015;35:275-87 pubmed publisher |
| Jesus P, Ouelaa W, François M, Riachy L, Guérin C, Aziz M, et al. Alteration of intestinal barrier function during activity-based anorexia in mice. Clin Nutr. 2014;33:1046-53 pubmed publisher |
| Baluk P, Fuxe J, Hashizume H, Romano T, Lashnits E, Butz S, et al. Functionally specialized junctions between endothelial cells of lymphatic vessels. J Exp Med. 2007;204:2349-62 pubmed |
