This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
alpha Catenin Polyclonal Antibody
catalog :
71-1200
quantity :
100 ug
price :
US 520.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, chicken
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 11
Reference
Knop J, Burkard N, Danesh M, Kintrup S, Dandekar T, Srivastava M, et al. Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling. iScience. 2023;26:108049 pubmed publisher
Jiang C, Javed A, Kaiser L, Nava M, Xu R, Brandt D, et al. Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021;12:1308 pubmed publisher
Otsu K, Ida Yonemochi H, Ikezaki S, Ema M, Hitomi J, Ohshima H, et al. Oxygen regulates epithelial stem cell proliferation via RhoA-actomyosin-YAP/TAZ signal in mouse incisor. Development. 2021;148: pubmed publisher
Duncan Lowey J, Wiscovitch A, Wood T, Goldberg M, Russo B. Shigella flexneri Disruption of Cellular Tension Promotes Intercellular Spread. Cell Rep. 2020;33:108409 pubmed publisher
Teo J, Tomatis V, Coburn L, Lagendijk A, Schouwenaar I, Budnar S, et al. Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion. Mol Biol Cell. 2020;31:2557-2569 pubmed publisher
Ding Y, Yang J, Chen P, Lu T, Jiao K, Tester D, et al. Knockout of SORBS2 Protein Disrupts the Structural Integrity of Intercalated Disc and Manifests Features of Arrhythmogenic Cardiomyopathy. J Am Heart Assoc. 2020;9:e017055 pubmed publisher
Wee K, Hediyeh Zadeh S, Duszyc K, Verma S, N Nanavati B, Khare S, et al. Snail induces epithelial cell extrusion by regulating RhoA contractile signalling and cell-matrix adhesion. J Cell Sci. 2020;133: pubmed publisher
Lough K, Byrd K, Descovich C, Spitzer D, Bergman A, BEAUDOIN G, et al. Telophase correction refines division orientation in stratified epithelia. elife. 2019;8: pubmed publisher
Acharya B, Nestor Bergmann A, Liang X, Gupta S, Duszyc K, Gauquelin E, et al. A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress. Dev Cell. 2018;47:439-452.e6 pubmed publisher
Vite A, Zhang C, Yi R, Emms S, Radice G. α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart. Development. 2018;145: pubmed publisher
Liang X, Budnar S, Gupta S, Verma S, Han S, Hill M, et al. Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nat Commun. 2017;8:790 pubmed publisher
product information
Product Type :
Antibody
Product Name :
alpha Catenin Polyclonal Antibody
Catalog # :
71-1200
Quantity :
100 ug
Price :
US 520.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Chicken, Human, Mouse, Rat, Xenopus laevis
Applications :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1-2 ug/mL
Species :
Chicken, Human, Mouse, Rat, Xenopus laevis
Isotype :
IgG
Storage :
-20 C
Description :
Alpha catenin is a member of the b-catenin family of cytosolic proteins. Alpha catenin interacts with N-cadherin and b-catenin on the cytosolic side of adherins junctions to mediate the interaction with the actin cytoskeleton. Alpha catenin is a homodimer in solution, but dissociates to form a 1:1 heterodimer with b-catenin in order to interact with cadherins. It also regulates morphological plasticity of synapses and cerebellar and hippocampal lamination during development. Alpha catenin also functions in the control of the startle modulation.
Immunogen :
Human alpha Catenin
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1-2 ug/mL
Aliases :
102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI481747; AI988031; alpha E catenin; alpha E-catenin; Alpha N-catenin; alpha(E)-catenin; alpha(N)-catenin; alpha-catenin; alpha-catenin-related protein; alpha-E-catenin; alphaE-catenin; alpha-N-catenin; alphaN-catenin; cadherin associated protein; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; CAP102; CAPR; CAP-R; catenin; catenin (cadherin associated protein), alpha 1; catenin (cadherin associated protein), alpha 2; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; catenin alpha 1; catenin alpha 2; Catenin alpha1; catenin alpha-1; Catenin alpha2; Catenin alpha-2; catenin, alpha 1; Catenin-alpha1; Catenin-alpha2; Catna; Catna1; Catna2; cdf; cerebellar deficient folia; chp; CT114; CTNNA1; Ctnna2; CTNR; FLJ36832; FLJ52416; HGNC:2509; MDPT2; Neural alpha-catenin; NY-REN-13 antigen; renal carcinoma antigen NY-REN-13
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA