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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
N-Ras Recombinant Rabbit Monoclonal Antibody (10H6L11)
catalog :
703435
quantity :
100 µg
price :
US 500.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
10H6L11
reactivity :
human, mouse
application :
western blot, immunocytochemistry
more info or order :
Invitrogen product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 1e
Chen S, Vedula R, Cuevas Navarro A, Lu B, Hogg S, Wang E, et al. Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation. Cancer Discov. 2022;12:2434-2453 pubmed publisher
product information
Product Type :
Antibody
Product Name :
N-Ras Recombinant Rabbit Monoclonal Antibody (10H6L11)
Catalog # :
703435
Quantity :
100 µg
Price :
US 500.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 1:100, Western Blot: 1:5,000
Species :
Human
Clone :
10H6L11
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
NRAS (GTPase NRas) is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML) and Noonan syndrome 6.
Immunogen :
Peptides corresponding to human N-Ras [1) aa83-aa98 2) aa166-aa180]
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100, Western Blot: 1:5,000
Aliases :
ALPS4; AV095280; CMNS; GTPase NRas; HRAS1; NCMS; Neuroblastoma RAS; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; Nras; N-ras; N-ras protein part 4; NRAS1; NS6; RAS; RASN; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA