BRD4 Recombinant Rabbit Monoclonal Antibody (14H4L4) | Invitrogen 702448 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BRD4 Recombinant Rabbit Monoclonal Antibody (14H4L4)

catalog :

702448

quantity :

100 ug

price :

US 450.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

14H4L4

reactivity :

human

application :

western blot, immunocytochemistry

citations: 2

Reference
Li Z, Deeks S, Ott M, Greene W. Comprehensive synergy mapping links a BAF- and NSL-containing "supercomplex" to the transcriptional silencing of HIV-1. Cell Rep. 2023;42:113055 pubmed publisher
Yigitliler A, Renner J, Simon C, Schneider M, Stubenrauch F, Iftner T. BRD4S interacts with viral E2 protein to limit human papillomavirus late transcription. J Virol. 2021;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

BRD4 Recombinant Rabbit Monoclonal Antibody (14H4L4)

Catalog # :

702448

Quantity :

100 ug

Price :

US 450.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

ChIP Assay: 2.5 ug/1x10^6 cells, Immunocytochemistry: 2 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human

Clone :

14H4L4

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.

Immunogen :

Protein corresponding to human BRD4 (aa154-aa284)

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 2.5 ug/1x10^6 cells, Immunocytochemistry: 2 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; bromodomain-containing protein 4; bromodomain-containing protein 4; LOW QUALITY PROTEIN: bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; mitotic chromosome-associated protein; Protein HUNK1; WI-11513