PIP5K1C Recombinant Rabbit Monoclonal Antibody (16H4L5) | Invitrogen 702444 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PIP5K1C Recombinant Rabbit Monoclonal Antibody (16H4L5)

catalog :

702444

quantity :

100 ug

price :

US 471.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

16H4L5

reactivity :

human

application :

western blot, immunocytochemistry

citations: 1

Reference
Cizkova K, Koubová K, Tauber Z. Lipid Messenger Phosphatidylinositol-4,5-Bisphosphate Is Increased by Both PPARα Activators and Inhibitors: Relevance for Intestinal Cell Differentiation. Biology (Basel). 2022;11: pubmed publisher

product information

Product Type :

Antibody

Product Name :

PIP5K1C Recombinant Rabbit Monoclonal Antibody (16H4L5)

Catalog # :

702444

Quantity :

100 ug

Price :

US 471.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 5 ug/mL, Western Blot: 2.5 ug/mL

Species :

Human

Clone :

16H4L5

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

PIP5K1C lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with -beta-catenin and increases -beta-catenin activity downstream of growth factor stimulation. PIP5K1C expression and kinase activity enhance -beta-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitation of RhoA GTPase and integrin activation by chemo attractants.

Immunogen :

Peptides corresponding to human Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma [1) aa537-aa551 2) aa330-aa347]

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Western Blot: 2.5 ug/mL

Aliases :

AI115456; AI835305; diphosphoinositide kinase; Kiaa0589; LCCS3; phosphatidylinositol 4-phosphate 5-kinase type I gamma; Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; Pip5k1c; PIP5K1-gamma; PIP5Kgamma; PIP5K-GAMMA; PIP5KI gamma; Pip5kIgamma; PIP5KI-gamma; PIPKIg_v4; ptdIns(4)P-5-kinase 1 gamma; ptdIns(4)P-5-kinase gamma; ptdInsPKIgamma; type I PIP kinase