product summary
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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Glutamine Synthetase Recombinant Rabbit Monoclonal Antibody (7H9L16)
catalog :
701989
quantity :
100 ug
price :
US 450.00
clonality :
recombinant
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
7H9L16
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...
Brown M, Gibson K, Schmidt M, Walters D, Arning E, Bottiglieri T, et al. Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase-deficient mice. JIMD Rep. 2020;56:58-69 pubmed publisher
Henao Restrepo J, L xf3 pez Murillo C, Valderrama Carmona P, Orozco Santa N, Gomez J, Guti xe9 rrez Vargas J, et al. Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection. Brain Pathol. 2023;33:e13119 pubmed publisher
González Molina L, Villar Vesga J, Henao Restrepo J, Villegas A, Lopera F, Cardona Gómez G, et al. Extracellular Vesicles From 3xTg-AD Mouse and Alzheimer's Disease Patient Astrocytes Impair Neuroglial and Vascular Components. Front Aging Neurosci. 2021;13:593927 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Glutamine Synthetase Recombinant Rabbit Monoclonal Antibody (7H9L16)
Catalog # :
701989
Quantity :
100 ug
Price :
US 450.00
Clonality :
Recombinant Monoclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: 1-2 ug/mL
Species :
Human, Mouse, Rat
Clone :
7H9L16
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
Immunogen :
Protein corresponding to Human GLUL (aa 2-373)
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 2 ug/mL, Immunohistochemistry (Frozen): Assay-dependent, Western Blot: 1-2 ug/mL
Aliases :
cell proliferation-inducing protein 59; GLNA; GLNS; Glul; GLUL protein; Glutamate ammonia ligase; glutamate decarboxylase; glutamate-ammonia ligase; glutamate--ammonia ligase; glutamate-ammonia ligase (glutamine synthase); glutamate-ammonia ligase (glutamine synthetase); glutamine synthase; glutamine synthetase; Glutamine synthetase (glutamate-ammonia ligase); glutamine synthetase 1; glutamine synthetase I; GS; Palmitoyltransferase GLUL; PIG43; PIG59; Proliferation inducing protein 43; proliferation-inducing protein 43
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA