Glutaminase Recombinant Rabbit Monoclonal Antibody (6H5L15) | Invitrogen 701965 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Glutaminase Recombinant Rabbit Monoclonal Antibody (6H5L15)

catalog :

701965

quantity :

100 ug

price :

US 520.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

6H5L15

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig s7b	Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
	Liu P, Chen Y, Li X, Hsueh P, Tzeng S, Chen H, et al. CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions. Nat Immunol. 2023;24:452-462 pubmed publisher
	Vacek L, Dvořák A, Bechynska K, Kosek V, Elkalaf M, Trinh M, et al. Hypoxia Induces Saturated Fatty Acids Accumulation and Reduces Unsaturated Fatty Acids Independently of Reverse Tricarboxylic Acid Cycle in L6 Myotubes. Front Endocrinol (Lausanne). 2022;13:663625 pubmed publisher
	Rossiter N, Huggler K, Adelmann C, Keys H, Soens R, Sabatini D, et al. CRISPR screens in physiologic medium reveal conditionally essential genes in human cells. Cell Metab. 2021;33:1248-1263.e9 pubmed publisher
	Kim S, Mehta H, Wan J, Kuehnemann C, Chen J, Hu J, et al. Mitochondrial peptides modulate mitochondrial function during cellular senescence. Aging (Albany NY). 2018;10:1239-1256 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Glutaminase Recombinant Rabbit Monoclonal Antibody (6H5L15)

Catalog # :

701965

Quantity :

100 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 2 ug/mL, Western Blot: 1-2 ug/mL

Species :

Human, Mouse, Rat

Clone :

6H5L15

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Glutaminase is a phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. It is primarily expressed in the brain and kidney and plays an essential role in generating energy for metabolism, synthesizing neurotransmitter glutamate, and maintaing acid-based balance in the kidney. There are alternate splicing results in multiple transcript variants in the Glutaminase gene.

Immunogen :

Protein corresponding to Human GLS (aa 251-533)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 2 ug/mL, Western Blot: 1-2 ug/mL

Aliases :

6330442B14; AAD20; AI314027; B230365M23Rik; DKFZp686O15119; FLJ10358; GA; GAC; GAM; GLS; GLS1; Glut; glutaminase; glutaminase C; glutaminase kidney isoform, mitochondrial; Glutaminase kidney isoform, mitochondrial 65 kDa chain; Glutaminase kidney isoform, mitochondrial 68 kDa chain; glutaminase, phosphate-activated; KGA; K-glutaminase; KIAA0838; L-glutamine amidohydrolase; PAG; phosphate-activated glutaminase; RATGLUT

more info or order :

Invitrogen product webpage