alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (7H1L69)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (7H1L69)

catalog :

701914

quantity :

100 ug

price :

US 520.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

7H1L69

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

citations: 6

Reference
Wang C, Xie B, Yin S, Cao J, Huang J, Jin L, et al. Induction of filopodia formation by α-Actinin-2 via RelA with a feedforward activation loop promoting overt bone marrow metastasis of gastric cancer. J Transl Med. 2023;21:399 pubmed publisher
Menzele A, Aboalgasm H, Ballo R, Gwanyanya A. Hyperglycaemia-induced impairment of the autorhythmicity and gap junction activity of mouse embryonic stem cell-derived cardiomyocyte-like cells. Histochem Cell Biol. 2023;159:329-337 pubmed publisher
Ilouz N, Harazi A, Guttman M, Daya A, Ruppo S, Yakovlev L, et al. In vivo and in vitro genome editing to explore GNE functions. Front Genome Ed. 2022;4:930110 pubmed publisher
Ronaldson Bouchard K, Teles D, Yeager K, Tavakol D, Zhao Y, Chramiec A, et al. A multi-organ chip with matured tissue niches linked by vascular flow. Nat Biomed Eng. 2022;6:351-371 pubmed publisher
Grafton F, Ho J, Ranjbarvaziri S, Farshidfar F, Budan A, Steltzer S, et al. Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes. elife. 2021;10: pubmed publisher
Shrestha A, Sultana R, Lee C, Ogundele O. SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β Dynamics. Front Synaptic Neurosci. 2019;11:18 pubmed publisher

product information

Product Type :

Antibody

Product Name :

alpha Actinin 2 Recombinant Rabbit Monoclonal Antibody (7H1L69)

Catalog # :

701914

Quantity :

100 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 2 ug/mL, Western Blot: 0.5 ug/mL

Species :

Human, Mouse, Rat

Clone :

7H1L69

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it i involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

Immunogen :

Peptides corresponding to human Sarcomeric alpha actinin/alpha actinin 2 [1) aa834-aa852, 2) aa5-aa24]

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): 2 ug/mL, Western Blot: 0.5 ug/mL

Aliases :

1110008F24Rik; actinin alpha 2; actinin, alpha 2; ACTN2; alpha-actinin skeletal muscle; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin-2; CMD1AA; CMH23; F-actin cross-linking protein