MMP13 Recombinant Rabbit Monoclonal Antibody (3H13L17) | Invitrogen 701287 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MMP13 Recombinant Rabbit Monoclonal Antibody (3H13L17)

catalog :

701287

quantity :

100 µg

price :

US 375.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

3H13L17

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s1b	Solomonov I, Zehorai E, Talmi Frank D, Wolf S, Shainskaya A, Zhuravlev A, et al. Distinct biological events generated by ECM proteolysis by two homologous collagenases. Proc Natl Acad Sci U S A. 2016;113:10884-9 pubmed publisher
	Juin S, Pushpakumar S, Sen U. GYY4137 Regulates Extracellular Matrix Turnover in the Diabetic Kidney by Modulating Retinoid X Receptor Signaling. Biomolecules. 2021;11: pubmed publisher
	Zhang M, Zhang R, Zheng T, Chen Z, Ji G, Peng F, et al. Xanthohumol Attenuated Inflammation and ECM Degradation by Mediating HO-1/C/EBPβ Pathway in Osteoarthritis Chondrocytes. Front Pharmacol. 2021;12:680585 pubmed publisher
	Zimmerli D, Cecconi V, Valenta T, Hausmann G, Cantù C, Restivo G, et al. WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma. Oncogene. 2018;37:3753-3762 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MMP13 Recombinant Rabbit Monoclonal Antibody (3H13L17)

Catalog # :

701287

Quantity :

100 µg

Price :

US 375.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1-3 µg/mL

Species :

Human

Clone :

3H13L17

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.

Immunogen :

Recombinant protein corresponding to amino acids 221–471 of human MMP-13

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1 µg/mL, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1-3 µg/mL

Aliases :

cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13

more info or order :

Invitrogen product webpage