Phospho-Rb (Ser780) Recombinant Rabbit Monoclonal Antibody (13H9L5)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-Rb (Ser780) Recombinant Rabbit Monoclonal Antibody (13H9L5)

catalog :

701272

quantity :

100 ug

price :

US 450.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

13H9L5

reactivity :

human

application :

western blot, immunocytochemistry

citations: 1

Reference
Araki K, Kawauchi K, Hirata H, Yamamoto M, Taya Y. Cytoplasmic translocation of the retinoblastoma protein disrupts sarcomeric organization. elife. 2013;2:e01228 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-Rb (Ser780) Recombinant Rabbit Monoclonal Antibody (13H9L5)

Catalog # :

701272

Quantity :

100 ug

Price :

US 450.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1-2 ug/mL, Western Blot: 1-3 ug/mL

Species :

Human

Clone :

13H9L5

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

Immunogen :

Phosphopeptide corresponding to amino acids 775–786 of human Retinoblastoma [pS780]

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-2 ug/mL, Western Blot: 1-3 ug/mL

Aliases :

Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein