Phospho-EIF2S1 (Ser51) Recombinant Rabbit Monoclonal Antibody (10H21L20)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-EIF2S1 (Ser51) Recombinant Rabbit Monoclonal Antibody (10H21L20)

catalog :

701268

quantity :

100 ug

price :

US 520.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

10H21L20

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
van Galen P, Mbong N, Kreso A, Schoof E, Wagenblast E, Ng S, et al. Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. Cell Rep. 2018;25:1109-1117.e5 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-EIF2S1 (Ser51) Recombinant Rabbit Monoclonal Antibody (10H21L20)

Catalog # :

701268

Quantity :

100 ug

Price :

US 520.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1-2 ug/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 2-3 ug/mL

Species :

Human

Clone :

10H21L20

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

EIF2a (Eukaryotic translation initiation factor 2A) is a heterotrimer composed of three subunits (alpha, beta, and gamma). This translation initiation factor drives binding of initiator methionyl-tRNA to the 40S ribosome in an AUG-dependent manner to form the 43S pre-initiation complex. The polypeptide can be phosphorylated by related protein kinases activated in response to stress. Phosphorylated EIF2A inhibits EIF2B activity and prevents guanine nucleotide exchange.

Immunogen :

Phosphopeptide corresponding to amino acids 48–57 of human Eukaryotic translation initiation factor 2A [pS51]

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-2 ug/mL, Immunohistochemistry (Paraffin): 1:20, Western Blot: 2-3 ug/mL

Aliases :

0910001O23Rik; 2410026C18Rik; 35kDa; EIF2; EIF-2; eIF2 alpha; eIF2 alpha subunit; EIF2A; eIF-2A; eIF2alpha; EIF-2alpha; eIF-2-alpha; EIF2S1; eif2s1b; Eukaryotic translation initiation factor 2 subunit 1; eukaryotic translation initiation factor 2 subunit 1b; eukaryotic translation initiation factor 2 subunit alpha; eukaryotic translation initiation factor 2, subunit 1 alpha; eukaryotic translation initiation factor 2, subunit 1 alpha b; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 2A; fb19d01; translation initiation factor subunit; wu:fb19d01