APOE Recombinant Rabbit Monoclonal Antibody (16H22L18) | Invitrogen 701241 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

APOE Recombinant Rabbit Monoclonal Antibody (16H22L18)

catalog :

701241

quantity :

100 µg

price :

US 425.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

16H22L18

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig ex8a	Culemann S, Grüneboom A, Nicolás Ávila J, Weidner D, Lämmle K, Rothe T, et al. Locally renewing resident synovial macrophages provide a protective barrier for the joint. Nature. 2019;572:670-675 pubmed publisher
immunocytochemistry; human; loading ...; fig s6a	Huang Y, Zhou B, Wernig M, Sudhof T. ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and A? Secretion. Cell. 2017;168:427-441.e21 pubmed publisher
	Zhang Z, Na H, Gan Q, Tao Q, Alekseyev Y, Hu J, et al. Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?. Aging Cell. 2021;20:e13501 pubmed publisher
	Kang S, Ahn E, Liu X, Bryson M, Miller G, Weinshenker D, et al. ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer's disease. Acta Neuropathol. 2021;142:139-158 pubmed publisher
	Cui H, Jiang D, Banerjee S, Xie N, Kulkarni T, Liu R, et al. Monocyte-derived alveolar macrophage apolipoprotein E participates in pulmonary fibrosis resolution. JCI Insight. 2020;5: pubmed publisher
	Huang Y, Zhou B, Nabet A, Wernig M, Sudhof T. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk. J Neurosci. 2019;39:7408-7427 pubmed publisher
	Wang W, Hou T, Jia L, Wu Q, Quan M, Jia J. Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury. EBioMedicine. 2019;42:174-187 pubmed publisher

product information

Product Type :

Antibody

Product Name :

APOE Recombinant Rabbit Monoclonal Antibody (16H22L18)

Catalog # :

701241

Quantity :

100 µg

Price :

US 425.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1-3 µg/mL, Western Blot: 2-4 µg/mL

Species :

Human, Mouse, Rat

Clone :

16H22L18

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Apo E (Apolipoprotein E) plays an important role in the metabolism of lipids in the plasma, and is also is a constituent of various plasma lipoprotein-lipid particles. The protein is synthesized in liver, brain, spleen, and the kidney, and concentrations are high in interstitial fluids, where it plays a role in distributing cholesterol from cells where cholesterol is in excess to cells which require cholesterol. Apo E also plays an important role in the formation of very low density lipoprotein and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13. 2.

Immunogen :

Peptide corresponding to amino acids 240–251 of human ApoE

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1-3 µg/mL, Western Blot: 2-4 µg/mL

Aliases :

AD2; AI255918; APOE; apo-E; ApoE4; APOEA; Apolipoprotein; apolipoprotein E; apolipoprotein E3; apolipoprotein E4; Apoprotein; B2G1; BG; LDLCQ5; LPG; MGC1571

more info or order :

Invitrogen product webpage