STAT6 Recombinant Rabbit Monoclonal Antibody (21HCLC) | Invitrogen 701110 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

STAT6 Recombinant Rabbit Monoclonal Antibody (21HCLC)

catalog :

701110

quantity :

100 ug

price :

US 572.00

clonality :

recombinant

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

21HCLC

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Yu W, Singh R, Wang Z, O Malley B, Yi P. The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1. J Biol Chem. 2021;296:100739 pubmed publisher

product information

Product Type :

Antibody

Product Name :

STAT6 Recombinant Rabbit Monoclonal Antibody (21HCLC)

Catalog # :

701110

Quantity :

100 ug

Price :

US 572.00

Clonality :

Recombinant Monoclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ChIP Assay: 3 ug, Immunocytochemistry: 1-3 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1-3 ug/mL

Species :

Human, Mouse

Clone :

21HCLC

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

Immunogen :

Peptide corresponding to amino acids 630–638 of human singal transducer and activator of transcription 6

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 3 ug, Immunocytochemistry: 1-3 ug/mL, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1-3 ug/mL

Aliases :

12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT